Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1

Journal of Medicinal Chemistry

Volumn 55, Issue 17, 2012, Pages 7378-7391

  Hazeldine, Stuart ^a   Pachaiyappan, Boobalan ^c   Steinbergs, Nora ^b   Nowotarski, Shannon ^b   Hanson, Allison S ^a   Casero, Robert A ^b   Woster, Patrick M ^c  

^a WAYNE STATE UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDOXIME DERIVATIVE; ANTINEOPLASTIC AGENT; CADHERIN; GUANIDINE DERIVATIVE; H CADHERIN; HISTONE 3 LYSINE 4; HISTONE DEMETHYLASE; LYSINE SPECIFIC DEMETHYLASE 1; SECRETED FRIZZLED RELATED PROTEIN 2; THIOUREA DERIVATIVE; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG; UREA;

ARTICLE; CANCER CELL CULTURE; CHROMATIN; CONTROLLED STUDY; GENE SILENCING; HISTONE METHYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG CARCINOMA; TUMOR SUPPRESSOR GENE;

ENZYME INHIBITORS; HISTONE DEMETHYLASES; HUMANS; MODELS, MOLECULAR; MOLECULAR WEIGHT; OXIMES; TUMOR CELLS, CULTURED;

EID: 84866327150     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm3002845     Document Type: Article

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