Catalytic roles for carbon-oxygen hydrogen bonding in SET domain lysine methyltransferases

Journal of Biological Chemistry

Volumn 281, Issue 28, 2006, Pages 19280-19287

  Couture, Jean François ^a   Hauk, Glenn ^a,c   Thompson, Mark J ^b   Blackburn, G Michael ^b   Trievel, Raymond C ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINES; BIOCHEMICAL ENGINEERING; CATALYSTS; HYDROGEN BONDS; SUBSTRATES;

AMMONIUM METHYL GROUPS; CARBON-OXYGEN HYDROGEN BONDING; EUKARYOTES; SUBSTRATE RECOGNITION;

ENZYMES;

AMINE; CARBON; HETEROCYCLIC COMPOUND; LYSINE; METHYL GROUP; METHYLTRANSFERASE; OXYGEN; RIBULOSEBISPHOSPHATE CARBOXYLASE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; SET ENZYME; SINEFUNGIN; TRIMETHYLAMMONIUM SALT DERIVATIVE; TRIMETHYLLYSINE; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; CATALYSIS; CHEMICAL ANALYSIS; CRYSTAL STRUCTURE; HYDROGEN BOND; PEA; PRIORITY JOURNAL; STEREOCHEMISTRY;

ARABIDOPSIS; BINDING SITES; CARBON; CATALYSIS; CLONING, MOLECULAR; HISTONE-LYSINE N-METHYLTRANSFERASE; HYDROGEN BONDING; KINETICS; LYSINE; OXYGEN; PROTEIN STRUCTURE, TERTIARY;

EUKARYOTA; PISUM SATIVUM;

EID: 33745842198     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M602257200     Document Type: Article

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