A mechanism-based inactivator for histone demethylase LSD1

Journal of the American Chemical Society

Volumn 128, Issue 14, 2006, Pages 4536-4537

  Culhane, Jeffrey C ^a   Szewczuk, Lawrence M ^a   Liu, Xin ^b   Da, Guoping ^b   Marmorstein, Ronen ^b   Cole, Philip A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); ENZYME INHIBITOR; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE INHIBITOR; LYSINE; MONOAMINE OXIDASE INHIBITOR; PARGYLINE; PROTEIN LSD1; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CONCENTRATION RESPONSE; DOSE TIME EFFECT RELATION; DRUG SYNTHESIS; ENZYME INACTIVATION; ENZYME MECHANISM;

AMINO ACID SEQUENCE; ENZYME ACTIVATION; ENZYME INHIBITORS; FLAVIN-ADENINE DINUCLEOTIDE; HISTONE DEACETYLASES; KINETICS; LYSINE; MOLECULAR SEQUENCE DATA; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33646061354     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0602748     Document Type: Article

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