Structure-based virtual screening of chemical libraries for drug discovery

Current Opinion in Chemical Biology

Volumn 10, Issue 3, 2006, Pages 194-202

  Ghosh, Sutapa ^a   Nie, Aihua ^a   An, Jing ^a,b   Huang, Ziwei ^a  

^a BURNHAM INSTITUTE   (United States)

^b Chemokine Pharmaceutical Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 6 BROMO 4 (1 CYANO 2 ETHOXY 2 OXOETHYL) 4H CHROMENE 3 CARBOXYLIC ACID ETHYL ESTER; G PROTEIN COUPLED RECEPTOR; HORMONE RECEPTOR; METALLOPROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE; PROTEINASE;

APOPTOSIS; BINDING AFFINITY; BIOLOGICAL ACTIVITY; BIOLOGY; CHEMICAL ANALYSIS; COMBINATORIAL CHEMISTRY; COMPLEX FORMATION; COMPUTER PROGRAM; COST; DATA BASE; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG RESEARCH; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; HIGH THROUGHPUT SCREENING; LIBRARY; PHYSICAL CHEMISTRY; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; REVIEW; SCORING SYSTEM; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINESTERASE; ALGORITHMS; APOPTOSIS; CHOLINESTERASE INHIBITORS; DATABASE MANAGEMENT SYSTEMS; DRUG DESIGN; MOLECULAR STRUCTURE; RECEPTORS, ESTROGEN; RECEPTORS, G-PROTEIN-COUPLED;

EID: 33744551693     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbpa.2006.04.002     Document Type: Review

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