A small-molecule probe of the histone methyltransferase G9a induces cellular senescence in pancreatic adenocarcinoma

ACS Chemical Biology

Volumn 7, Issue 7, 2012, Pages 1152-1157

  Yuan, Yuan ^a,c   Wang, Qiu ^a,e   Paulk, Joshiawa ^a,d   Kubicek, Stefan ^a,f   Kemp, Melissa M ^a   Adams, Drew J ^a   Shamji, Alykhan F ^a   Wagner, Bridget K ^a   Schreiber, Stuart L ^a,b,c,d  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c HARVARD UNIVERSITY   (United States)

^d HARVARD UNIVERSITY   (United States)

^e DUKE UNIVERSITY   (United States)

^f ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BRD 4770; HISTONE LYSINE METHYLTRANSFERASE INHIBITOR; HISTONE METHYLTRANSFERASE; LYSINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CHROMATIN STRUCTURE; DNA METHYLATION; EUCHROMATIN; HISTONE METHYLATION; HISTONE MODIFICATION; HUMAN; HUMAN CELL; PANCREAS ADENOCARCINOMA; PRIORITY JOURNAL; SENESCENCE;

ADENOCARCINOMA; CELL AGING; CELL LINE, TUMOR; ENZYME INHIBITORS; HELA CELLS; HISTOCOMPATIBILITY ANTIGENS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; MOLECULAR PROBES; PANCREATIC NEOPLASMS;

EID: 84864140929     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300139y     Document Type: Article

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