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Volumn 49, Issue 3, 2014, Pages 1212-1244

Systematic review of protein biomarkers of invasive behavior in glioblastoma

Author keywords

Glioblastoma; High grade glioma; Invasion; Invasiveness; Protein biomarkers

Indexed keywords

ANGIOGENIC FACTOR; BIOLOGICAL MARKER; CALPAIN 2; CATHEPSIN B; CATHEPSIN D; CATHEPSIN S; CELL ADHESION MOLECULE; CHEMOKINE; COLLAGENASE 3; CYSTEINE RICH PROTEIN 61; CYTOKINE; EZRIN; FASCIN; GALECTIN 1; GALECTIN 3; GELATINASE A; GELATINASE B; MATRIX METALLOPROTEINASE 14; OSTEONECTIN; OSTEOPONTIN; PLACENTA PROTEIN 5; PLASMINOGEN ACTIVATOR INHIBITOR 1; SCLEROPROTEIN; TEMOZOLOMIDE; TENASCIN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 4; TRANSCRIPTION FACTOR; UNINDEXED DRUG; VASCULOTROPIN; TUMOR MARKER;

EID: 84902553619     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8593-5     Document Type: Review
Times cited : (32)

References (320)
  • 1
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • doi:10.1056/NEJMra0708126
    • Wen PY, Kesari S (2008) Malignant gliomas in adults. N Engl J Med 359:492-507. doi:10.1056/NEJMra0708126
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 2
    • 74049090120 scopus 로고    scopus 로고
    • Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme
    • doi:10.1186/1471-2407-9-444
    • Verhoeff JJC, Van Tellingen O, Claes A et al (2009) Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme. BMC Cancer 9:444. doi:10.1186/1471-2407-9-444
    • (2009) BMC Cancer , vol.9 , pp. 444
    • Verhoeff, J.J.C.1    Van Tellingen, O.2    Claes, A.3
  • 4
    • 49649087701 scopus 로고    scopus 로고
    • Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis
    • doi:10.1158/1078-0432.CCR-07-4821
    • Reddy SP, Britto R, Vinnakota K et al (2008) Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis. Clin Cancer Res An Off J Am Assoc Cancer Res 14:2978-87. doi:10.1158/1078-0432. CCR-07-4821
    • (2008) Clin Cancer Res An off J Am Assoc Cancer Res , vol.14 , pp. 2978-2987
    • Reddy, S.P.1    Britto, R.2    Vinnakota, K.3
  • 5
    • 58949099258 scopus 로고    scopus 로고
    • Prognostic significance of c-Met expression in glioblastomas
    • doi:10.1002/cncr.23972
    • Kong D-S, Song S-Y, Kim D-H et al (2009) Prognostic significance of c-Met expression in glioblastomas. Cancer 115:140-8. doi:10.1002/cncr.23972
    • (2009) Cancer , vol.115 , pp. 140-148
    • Kong, D.-S.1    Song, S.-Y.2    Kim, D.-H.3
  • 7
    • 37549007198 scopus 로고    scopus 로고
    • Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis
    • doi:10.1158/1078-0432.CCR-06-2789
    • Shirahata M, Iwao-Koizumi K, Saito S et al (2007) Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis. Clin Cancer Res 13:7341-7356. doi:10.1158/1078-0432.CCR-06-2789
    • (2007) Clin Cancer Res , vol.13 , pp. 7341-7356
    • Shirahata, M.1    Iwao-Koizumi, K.2    Saito, S.3
  • 8
    • 0033499387 scopus 로고    scopus 로고
    • Brain tumor invasion rate measured in vitro does not correlate with Ki-67 expression
    • DOI 10.1023/A:1006375316331
    • Khoshyomn S, Lew S, DeMattia J et al (1999) Brain tumor invasion rate measured in vitro does not correlate with Ki-67 expression. J Neuro-Oncol 45:111-6 (Pubitemid 30197724)
    • (1999) Journal of Neuro-Oncology , vol.45 , Issue.2 , pp. 111-116
    • Khoshyomn, S.1    Lew, S.2    DeMattia, J.3    Singer, E.B.4    Penar, P.L.5
  • 9
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • doi:10.1016/j.ccr.2009.12.020
    • Verhaak RG, Hoadley KA, Purdom E et al (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98-110. doi:10.1016/j.ccr.2009.12.020
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3
  • 10
    • 41649102043 scopus 로고    scopus 로고
    • The cancer biomarker problem
    • doi:10.1038/nature06913
    • Sawyers CL (2008) The cancer biomarker problem. Nature 452:548-552. doi:10.1038/nature06913
    • (2008) Nature , vol.452 , pp. 548-552
    • Sawyers, C.L.1
  • 11
    • 78449292592 scopus 로고    scopus 로고
    • Calpain 2 is required for glioblastoma cell invasion: Regulation ofmatrixmetalloproteinase 2
    • doi:10.1007/s11064-010-0246-8
    • Jang HS, Lal S, Greenwood JA (2010) Calpain 2 is required for glioblastoma cell invasion: regulation ofmatrixmetalloproteinase 2. Neurochem Res 35:1796-804. doi:10.1007/s11064-010-0246-8
    • (2010) Neurochem Res , vol.35 , pp. 1796-1804
    • Jang, H.S.1    Lal, S.2    Greenwood, J.A.3
  • 12
    • 0242467470 scopus 로고    scopus 로고
    • Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
    • DOI 10.1242/jcs.00712
    • Joy AM, Beaudry CE, Tran NL et al (2003) Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. J Cell Sci 116:4409-4417. doi:10.1242/jcs.00712 (Pubitemid 37369596)
    • (2003) Journal of Cell Science , vol.116 , Issue.21 , pp. 4409-4417
    • Joy, A.M.1    Beaudry, C.E.2    Tran, N.L.3    Ponce, F.A.4    Holz, D.R.5    Demuth, T.6    Berens, M.E.7
  • 13
    • 17144398831 scopus 로고    scopus 로고
    • Possible future issues in the treatment of glioblastomas: Special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis
    • doi:10.1200/JCO. 2005.03.089
    • Lefranc F, Brotchi J, Kiss R (2005) Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol: Off J Am Soc Clin Oncol 23:2411-22. doi:10.1200/JCO. 2005.03.089
    • (2005) J Clin Oncol: Off J Am Soc Clin Oncol , vol.23 , pp. 2411-2422
    • Lefranc, F.1    Brotchi, J.2    Kiss, R.3
  • 14
    • 65549105990 scopus 로고    scopus 로고
    • NHERF-1:Modulator of glioblastoma cellmigration and invasion
    • Kislin KL, McDonough WS, Eschbacher JM et al (2009) NHERF-1:modulator of glioblastoma cellmigration and invasion. Neoplasia 11:377-387
    • (2009) Neoplasia , vol.11 , pp. 377-387
    • Kislin, K.L.1    McDonough, W.S.2    Eschbacher, J.M.3
  • 15
    • 0035866813 scopus 로고    scopus 로고
    • Sublethal irradiation promotes migration and invasiveness of glioma cells: Implications for radiotherapy of human glioblastoma
    • Wild-Bode C, Weller M, Rimner A et al (2001) Sublethal irradiation promotes migration and invasiveness of glioma cells: implications for radiotherapy of human glioblastoma. Cancer Res 61:2744-2750 (Pubitemid 32685864)
    • (2001) Cancer Research , vol.61 , Issue.6 , pp. 2744-2750
    • Wild-Bode, C.1    Weller, M.2    Rimner, A.3    Dichgans, J.4    Wick, W.5
  • 16
    • 41649112610 scopus 로고    scopus 로고
    • Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
    • doi:10.1212/01.wnl.0000304121.57857.38
    • Norden AD, Young GS, Setayesh K et al (2008) Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology 70:779-87. doi:10.1212/01.wnl.0000304121.57857.38
    • (2008) Neurology , vol.70 , pp. 779-787
    • Norden, A.D.1    Young, G.S.2    Setayesh, K.3
  • 17
    • 60649116273 scopus 로고    scopus 로고
    • Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: Impact on local control and patient survival
    • doi:10.3171/2008.4.17492
    • Narayana A, Kelly P, Golfinos J et al (2009) Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J Neurosurg 110:173-80. doi:10.3171/2008.4.17492
    • (2009) J Neurosurg , vol.110 , pp. 173-180
    • Narayana, A.1    Kelly, P.2    Golfinos, J.3
  • 19
    • 84869208017 scopus 로고    scopus 로고
    • Differential effects of low- and high-dose GW2974, a dual epidermal growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion
    • doi:10.1002/jnr.23140
    • Wang L, Liu Q, Zhao H et al (2013) Differential effects of low- and high-dose GW2974, a dual epidermal growth factor receptor and HER2 kinase inhibitor, on glioblastoma multiforme invasion. J Neurosci Res 91:128-37. doi:10.1002/jnr.23140
    • (2013) J Neurosci Res , vol.91 , pp. 128-137
    • Wang, L.1    Liu, Q.2    Zhao, H.3
  • 20
    • 67650648500 scopus 로고    scopus 로고
    • Endogenous tenascin-C enhances glioblastoma invasion with reactive change of surrounding brain tissue
    • doi:10.1111/j.1349-7006.2009.01189.x
    • Hirata E, Arakawa Y, Shirahata M et al (2009) Endogenous tenascin-C enhances glioblastoma invasion with reactive change of surrounding brain tissue. Cancer Sci 100:1451-1459. doi:10.1111/j.1349-7006.2009.01189.x
    • (2009) Cancer Sci , vol.100 , pp. 1451-1459
    • Hirata, E.1    Arakawa, Y.2    Shirahata, M.3
  • 21
    • 79952987082 scopus 로고    scopus 로고
    • miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion
    • doi:10.1016/j.ejca.2010.11.026
    • Fowler A, Thomson D, Giles K et al (2011) miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion. Eur J Cancer 47:953-963. doi:10.1016/j.ejca.2010.11.026
    • (2011) Eur J Cancer , vol.47 , pp. 953-963
    • Fowler, A.1    Thomson, D.2    Giles, K.3
  • 23
    • 33644782522 scopus 로고    scopus 로고
    • Serum YKL-40, a new prognostic biomarker in cancer patients?
    • doi:10.1158/1055-9965.EPI-05-0011
    • Johansen JS, Jensen BV, Roslind A et al (2006) Serum YKL-40, a new prognostic biomarker in cancer patients? Cancer Epidemiol Biomarkers Prev 15:194 - 202. doi:10.1158/1055-9965.EPI-05-0011
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 194-202
    • Johansen, J.S.1    Jensen, B.V.2    Roslind, A.3
  • 24
    • 77953374405 scopus 로고    scopus 로고
    • Molecular pathology in adult gliomas: Diagnostic, prognostic, and predictive markers
    • doi:10.1016/S1474-4422(10)70105-8
    • Jansen M, Yip S, Louis DN (2010) Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markers. Lancet Neurol 9:717-726. doi:10.1016/S1474-4422(10)70105-8
    • (2010) Lancet Neurol , vol.9 , pp. 717-726
    • Jansen, M.1    Yip, S.2    Louis, D.N.3
  • 33
    • 0034859529 scopus 로고    scopus 로고
    • Roles of membrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma
    • NakadaM, Kita D, Futami K et al (2001) Roles ofmembrane type 1 matrix metalloproteinase and tissue inhibitor of metalloproteinases 2 in invasion and dissemination of human malignant glioma. J Neurosurg 94:464-73. doi:10.3171/jns.2001.94.3.0464 (Pubitemid 32786027)
    • (2001) Journal of Neurosurgery , vol.94 , Issue.3 , pp. 464-473
    • Nakada, M.1    Kita, D.2    Futami, K.3    Yamashita, J.4    Fujimoto, N.5    Sato, H.6    Okada, Y.7
  • 35
    • 0034232398 scopus 로고    scopus 로고
    • Localization of gelatinase-A and gelatinase-B mRNA and protein in human gliomas
    • Raithatha SA, Muzik H, Rewcastle NB et al (2000) Localization of gelatinase-A and gelatinase-B mRNA and protein in human gliomas. Neuro-Oncology 2:145-50
    • (2000) Neuro-Oncology , vol.2 , pp. 145-150
    • Raithatha, S.A.1    Muzik, H.2    Rewcastle, N.B.3
  • 36
    • 71449101202 scopus 로고    scopus 로고
    • High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas
    • doi:10.1007/s00401-009-0592-2
    • Colin C, Voutsinos-Porche B, Nanni I et al (2009) High expression of cathepsin B and plasminogen activator inhibitor type-1 are strong predictors of survival in glioblastomas. Acta Neuropathol 118:745-754. doi:10.1007/s00401-009- 0592-2
    • (2009) Acta Neuropathol , vol.118 , pp. 745-754
    • Colin, C.1    Voutsinos-Porche, B.2    Nanni, I.3
  • 37
    • 80052030282 scopus 로고    scopus 로고
    • Identification of MMP-9 specific microRNA expression profile as potential targets of antiinvasion therapy in glioblastoma multiforme
    • doi:10.1016/j.brainres.2011.07.002
    • Yan W, Zhang W, Sun L et al (2011) Identification of MMP-9 specific microRNA expression profile as potential targets of antiinvasion therapy in glioblastoma multiforme. Brain Res 1411:108-15. doi:10.1016/j.brainres.2011.07. 002
    • (2011) Brain Res , vol.1411 , pp. 108-115
    • Yan, W.1    Zhang, W.2    Sun, L.3
  • 38
    • 0742270809 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2 and -9 expression in astrocytic tumors
    • DOI 10.1007/BF02483445
    • Kunishio K, Okada M, Matsumoto Y, Nagao S (2003) Matrix metalloproteinase-2 and -9 expression in astrocytic tumors. Brain Tumor Pathol 20:39-45 (Pubitemid 38146269)
    • (2003) Brain Tumor Pathology , vol.20 , Issue.2 , pp. 39-45
    • Kunishio, K.1    Okada, M.2    Matsumoto, Y.3    Nagao, S.4
  • 39
    • 79959187557 scopus 로고    scopus 로고
    • MMP-2 siRNA inhibits radiation-enhanced invasiveness in glioma cells
    • doi:10.1371/journal.pone.0020614
    • Badiga AV, Chetty C, Kesanakurti D et al (2011) MMP-2 siRNA inhibits radiation-enhanced invasiveness in glioma cells. PloS One 6:e20614. doi:10.1371/journal.pone.0020614
    • (2011) PloS One , vol.6
    • Badiga, A.V.1    Chetty, C.2    Kesanakurti, D.3
  • 40
    • 77957884258 scopus 로고    scopus 로고
    • Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity
    • Inoue A, Takahashi H, Harada H et al (2010) Cancer stem-like cells of glioblastoma characteristically express MMP-13 and display highly invasive activity. Int J Oncol 37:1121-31
    • (2010) Int J Oncol , vol.37 , pp. 1121-1131
    • Inoue, A.1    Takahashi, H.2    Harada, H.3
  • 41
    • 0034641107 scopus 로고    scopus 로고
    • Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3
    • DOI 10.1083/jcb.149.6.1309
    • Hotary K, Allen E, Punturieri A et al (2000) Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J Cell Biol 149:1309-23 (Pubitemid 30399683)
    • (2000) Journal of Cell Biology , vol.149 , Issue.6 , pp. 1309-1323
    • Hotary, K.1    Allen, E.2    Punturieri, A.3    Yana, I.4    Weiss, S.J.5
  • 43
    • 68149169092 scopus 로고    scopus 로고
    • Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
    • doi:10.1073/pnas.0804273106
    • Markovic DS, Vinnakota K, Chirasani S et al (2009) Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion. Proc Natl Acad Sci U S A 106:12530-5. doi:10.1073/pnas.0804273106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12530-12535
    • Markovic, D.S.1    Vinnakota, K.2    Chirasani, S.3
  • 44
    • 77953305545 scopus 로고    scopus 로고
    • Identification of potential serum biomarkers of glioblastoma: Serum osteopontin levels correlate with poor prognosis
    • doi:10.1158/1055-9965.EPI-09-1077
    • Sreekanthreddy P, Srinivasan H, Kumar DM et al (2010) Identification of potential serum biomarkers of glioblastoma: serum osteopontin levels correlate with poor prognosis. Cancer Epidemiol Biomarkers Prev 19:1409-1422. doi:10.1158/1055-9965.EPI-09-1077
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 1409-1422
    • Sreekanthreddy, P.1    Srinivasan, H.2    Kumar, D.M.3
  • 45
    • 77957602528 scopus 로고    scopus 로고
    • TIMP-4 and CD63: New prognostic biomarkers in human astrocytomas
    • doi:10.1038/modpathol.2010.136
    • Rorive S, Lopez XM, Maris C et al (2010) TIMP-4 and CD63: new prognostic biomarkers in human astrocytomas. Mod Pathol 23:1418-1428. doi:10.1038/ modpathol.2010.136
    • (2010) Mod Pathol , vol.23 , pp. 1418-1428
    • Rorive, S.1    Lopez, X.M.2    Maris, C.3
  • 46
    • 79951664438 scopus 로고    scopus 로고
    • Serum angiogenic profile of patients with glioblastoma identifies distinct tumor subtypes and shows that TIMP-1 is a prognostic factor
    • doi:10.1093/neuonc/noq170
    • Crocker M, Ashley S, Giddings I et al (2011) Serum angiogenic profile of patients with glioblastoma identifies distinct tumor subtypes and shows that TIMP-1 is a prognostic factor. Neuro-Oncol 13:99-108. doi:10.1093/neuonc/noq170
    • (2011) Neuro-Oncol , vol.13 , pp. 99-108
    • Crocker, M.1    Ashley, S.2    Giddings, I.3
  • 47
    • 70349308642 scopus 로고    scopus 로고
    • Low expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in glioblastoma predicts longer patient survival
    • doi:10.1007/s11060-009-9910-8
    • Aaberg-Jessen C, Christensen K, Offenberg H et al (2009) Low expression of tissue inhibitor of metalloproteinases-1 (TIMP-1) in glioblastoma predicts longer patient survival. J Neuro-Oncol 95:117-28. doi:10.1007/s11060-009-9910-8
    • (2009) J Neuro-Oncol , vol.95 , pp. 117-128
    • Aaberg-Jessen, C.1    Christensen, K.2    Offenberg, H.3
  • 49
    • 33746881103 scopus 로고    scopus 로고
    • Exploring the distinctive biological characteristics of pilocytic and low-grade diffuse astrocytomas using microarray gene expression profiles
    • doi:10.1097/01.jnen.0000228203.12292.a1
    • Rorive S, Maris C, Debeir O et al (2006) Exploring the distinctive biological characteristics of pilocytic and low-grade diffuse astrocytomas using microarray gene expression profiles. J Neuropathol Exp Neurol 65:794 - 807. doi:10.1097/01.jnen.0000228203.12292.a1
    • (2006) J Neuropathol Exp Neurol , vol.65 , pp. 794-807
    • Rorive, S.1    Maris, C.2    Debeir, O.3
  • 51
    • 77951709114 scopus 로고    scopus 로고
    • RECK-mediated inhibition of glioma migration and invasion
    • doi:10.1002/jcb.22472
    • Silveira Correa TC, Massaro RR, Brohem CA et al (2010) RECK-mediated inhibition of glioma migration and invasion. J Cell Biochem 110:52-61. doi:10.1002/jcb.22472
    • (2010) J Cell Biochem , vol.110 , pp. 52-61
    • Silveira Correa, T.C.1    Massaro, R.R.2    Brohem, C.A.3
  • 52
    • 0141841681 scopus 로고    scopus 로고
    • Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis
    • DOI 10.1038/sj.onc.1206535
    • Gondi CS, Lakka SS, Yanamandra N et al (2003) Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis. Oncogene 22:5967-75. doi:10.1038/sj.onc.1206535 (Pubitemid 37175875)
    • (2003) Oncogene , vol.22 , Issue.38 , pp. 5967-5975
    • Gondi, C.S.1    Lakka, S.S.2    Yanamandra, N.3    Siddique, K.4    Dinh, D.H.5    Olivero, W.C.6    Gujrati, M.7    Rao, J.S.8
  • 54
    • 0038181212 scopus 로고    scopus 로고
    • Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth
    • Lakka SS, Gondi CS, Yanamandra N et al (2003) Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth. Cancer Res 63:2454-61 (Pubitemid 36605183)
    • (2003) Cancer Research , vol.63 , Issue.10 , pp. 2454-2461
    • Lakka, S.S.1    Gondi, C.S.2    Yanamandra, N.3    Dinh, D.H.4    Olivero, W.C.5    Gujrati, M.6    Rao, J.S.7
  • 56
    • 20444470108 scopus 로고    scopus 로고
    • Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas
    • doi:10.1074/jbc.M408520200
    • Lakka SS, Gondi CS, Dinh DH et al (2005) Specific interference of urokinase-type plasminogen activator receptor and matrix metalloproteinase-9 gene expression induced by double-stranded RNA results in decreased invasion, tumor growth, and angiogenesis in gliomas. J Biol Chem 280:21882 - 21892. doi:10.1074/jbc.M408520200
    • (2005) J Biol Chem , vol.280 , pp. 21882-21892
    • Lakka, S.S.1    Gondi, C.S.2    Dinh, D.H.3
  • 58
    • 79959823579 scopus 로고    scopus 로고
    • Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells
    • doi:10.1007/s11060-010-0398-z
    • Takahashi S, Yamada-Okabe H, Hamada K et al (2011) Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells. J Neuro-Oncol 103:267-76. doi:10.1007/s11060-010- 0398-z
    • (2011) J Neuro-Oncol , vol.103 , pp. 267-276
    • Takahashi, S.1    Yamada-Okabe, H.2    Hamada, K.3
  • 61
    • 40549094955 scopus 로고    scopus 로고
    • High serum level of plasminogen activator inhibitor-1 predicts histological grade of intracerebral gliomas
    • Iwadate Y, Hayama M, Adachi A et al (2008) High serum level of plasminogen activator inhibitor-1 predicts histological grade of intracerebral gliomas. Anticancer Res 28:415-418 (Pubitemid 351362846)
    • (2008) Anticancer Research , vol.28 , Issue.1 B , pp. 415-418
    • Iwadate, Y.1    Hayama, M.2    Adachi, A.3    Matsutani, T.4    Nagai, Y.5    Hiwasa, T.6    Saeki, N.7
  • 62
    • 79956003228 scopus 로고    scopus 로고
    • Knockdown of TFPI-2 promotes migration and invasion of glioma cells
    • Gessler F, Voss V, Seifert V et al (2011) Knockdown of TFPI-2 promotes migration and invasion of glioma cells. Neurosci Let 497:49-54
    • (2011) Neurosci Let , vol.497 , pp. 49-54
    • Gessler, F.1    Voss, V.2    Seifert, V.3
  • 64
    • 75049084598 scopus 로고    scopus 로고
    • Post-translational regulation of cathepsin B, but not of other cysteine cathepsins, contributes to increased glioblastoma cell invasiveness in vitro
    • doi:10.1007/s12253-009-9175-8
    • Gole B, Duran Alonso MB, Dolenc V, Lah T (2009) Post-translational regulation of cathepsin B, but not of other cysteine cathepsins, contributes to increased glioblastoma cell invasiveness in vitro. Pathol Oncol Res 15:711-723. doi:10.1007/s12253-009-9175-8
    • (2009) Pathol Oncol Res , vol.15 , pp. 711-723
    • Gole, B.1    Duran Alonso, M.B.2    Dolenc, V.3    Lah, T.4
  • 65
    • 3042551389 scopus 로고    scopus 로고
    • Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas
    • DOI 10.1158/0008-5472.CAN-04-1243
    • Gondi CS, Lakka SS, Yanamandra N et al (2004) Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res 64:4069-77. doi:10.1158/0008-5472.CAN-04-1243 (Pubitemid 38807311)
    • (2004) Cancer Research , vol.64 , Issue.12 , pp. 4069-4077
    • Gondi, C.S.1    Lakka, S.S.2    Yanamandra, N.3    Olivero, W.C.4    Dinh, D.H.5    Gujrati, M.6    Tung, C.H.7    Weissleder, R.8    Rao, J.S.9
  • 66
    • 2942718949 scopus 로고    scopus 로고
    • Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis
    • doi:10.1038/sj.onc.1207616
    • Lakka SS, Gondi CS, Yanamandra N et al (2004) Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis. Oncogene 23:4681 -9. doi:10.1038/sj.onc.1207616
    • (2004) Oncogene , vol.23 , pp. 4681-4689
    • Lakka, S.S.1    Gondi, C.S.2    Yanamandra, N.3
  • 70
    • 77956025867 scopus 로고    scopus 로고
    • Glioblastoma invasion, cathepsin B, and the potential for both to be inhibited by auranofin, an old anti-rheumatoid arthritis drug
    • doi:10.1055/s-0029-1242756
    • Kast RE (2010) Glioblastoma invasion, cathepsin B, and the potential for both to be inhibited by auranofin, an old anti-rheumatoid arthritis drug. Central Eur Neurosurg 71:139-42. doi:10.1055/s-0029-1242756
    • (2010) Central Eur Neurosurg , vol.71 , pp. 139-142
    • Kast, R.E.1
  • 71
    • 79953045754 scopus 로고    scopus 로고
    • TGF-β1 promotes motility and invasiveness of glioma cells through activation of ADAM17
    • doi:10.3892/or.2011.1195
    • Lu Y, Jiang F, Zheng X et al (2011) TGF-β1 promotes motility and invasiveness of glioma cells through activation of ADAM17. Oncology Reports 25:1329-35. doi:10.3892/or.2011.1195
    • (2011) Oncology Reports , vol.25 , pp. 1329-1335
    • Lu, Y.1    Jiang, F.2    Zheng, X.3
  • 72
    • 33745689524 scopus 로고    scopus 로고
    • Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness
    • DOI 10.1097/01.jnen.0000229240.51490.d3, PII 0000507220060500000010
    • Wildeboer D, Naus S, Amy Sang QX et al (2006) Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness. J Neuropathol Exp Neurol 65:516-527. doi:10.1097/01 (Pubitemid 44297273)
    • (2006) Journal of Neuropathology and Experimental Neurology , vol.65 , Issue.5 , pp. 516-527
    • Wildeboer, D.1    Naus, S.2    Sang, Q.-X.A.3    Bartsch, J.W.4    Pagenstecher, A.5
  • 74
    • 84887185749 scopus 로고    scopus 로고
    • ADAM17 promotes U87 glioblastoma stem cell migration and invasion
    • doi:10.1016/j.brainres.2013.02.025
    • Chen X, Chen L, Chen J et al (2013) ADAM17 promotes U87 glioblastoma stem cell migration and invasion. Brain Res. doi:10.1016/j.brainres.2013.02.025
    • (2013) Brain Res
    • Chen, X.1    Chen, L.2    Chen, J.3
  • 75
    • 84874363020 scopus 로고    scopus 로고
    • ADAM17 regulates self-renewal and differentiation of U87 glioblastoma stem cells
    • doi:10.1016/j.neulet.2013.01.021
    • Chen X, Chen L, Zhang R et al (2013) ADAM17 regulates self-renewal and differentiation of U87 glioblastoma stem cells. Neurosci Lett 537:44-9. doi:10.1016/j.neulet.2013.01.021
    • (2013) Neurosci Lett , vol.537 , pp. 44-49
    • Chen, X.1    Chen, L.2    Zhang, R.3
  • 77
    • 8144222388 scopus 로고    scopus 로고
    • The emerging roles of human tissue kallikreins in cancer
    • DOI 10.1038/nrc1474
    • Borgono CA, Diamandis EP (2004) The emerging roles of human tissue kallikreins in cancer. Nat Rev Cancer 4:876-890 (Pubitemid 39472954)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.11 , pp. 876-890
    • Borgono, C.A.1    Diamandis, E.P.2
  • 80
    • 77951725566 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 upregulates matrix metalloproteinase-9 and induces human glioma invasion
    • doi:10.1158/0008-5472.CAN-09-3838
    • Liu L, Wu J, Ying Z et al (2010) Astrocyte elevated gene-1 upregulates matrix metalloproteinase-9 and induces human glioma invasion. Cancer Res 70:3750-3759. doi:10.1158/0008-5472.CAN-09-3838
    • (2010) Cancer Res , vol.70 , pp. 3750-3759
    • Liu, L.1    Wu, J.2    Ying, Z.3
  • 81
    • 73949102954 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1: A novel target for human glioma therapy
    • doi:10.1158/1535-7163.MCT-09-0752
    • Emdad L, Sarkar D, Lee SG et al (2010) Astrocyte elevated gene-1: a novel target for human glioma therapy.Mol Cancer Ther 9:79-88. doi:10.1158/1535-7163. MCT-09-0752
    • (2010) Mol Cancer Ther , vol.9 , pp. 79-88
    • Emdad, L.1    Sarkar, D.2    Lee, S.G.3
  • 82
    • 40449089338 scopus 로고    scopus 로고
    • Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1
    • DOI 10.1158/0008-5472.CAN-07-6164
    • Sarkar D, Park ES, Emdad L et al (2008) Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1. Cancer Res 68:1478-1484. doi:10.1158/0008-5472.CAN-07-6164 (Pubitemid 351346856)
    • (2008) Cancer Research , vol.68 , Issue.5 , pp. 1478-1484
    • Sarkar, D.1    Eun, S.P.2    Emdad, L.3    Lee, S.-G.4    Su, Z.-Z.5    Fisher, P.B.6
  • 85
    • 0036682413 scopus 로고    scopus 로고
    • Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma
    • Tanwar MK, Gilbert MR, Holland EC (2002) Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma. Cancer Res 62:4364-4368 (Pubitemid 34827294)
    • (2002) Cancer Research , vol.62 , Issue.15 , pp. 4364-4368
    • Tanwar, M.K.1    Gilbert, M.R.2    Holland, E.C.3
  • 88
    • 80755125534 scopus 로고    scopus 로고
    • SerumYKL-40 is a marker of prognosis and disease status in high-grade gliomas
    • Iwamoto FM, Hottinger AF, Karimi S et al (2011) SerumYKL-40 is a marker of prognosis and disease status in high-grade gliomas. Neuro Oncol 13(11):1244-1251
    • (2011) Neuro Oncol , vol.13 , Issue.11 , pp. 1244-1251
    • Iwamoto, F.M.1    Hottinger, A.F.2    Karimi, S.3
  • 89
    • 79551491340 scopus 로고    scopus 로고
    • CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells
    • doi:10.1002/ijc.25466
    • Ku BM, Lee YK, Ryu J et al (2011) CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells. Int J Cancer J Int Cancer 128:1316-26. doi:10.1002/ijc.25466
    • (2011) Int J Cancer J Int Cancer , vol.128 , pp. 1316-1326
    • Ku, B.M.1    Lee, Y.K.2    Ryu, J.3
  • 90
    • 12144286634 scopus 로고    scopus 로고
    • Cyr61 Is Overexpressed in Gliomas and Involved in Integrin-Linked Kinase-Mediated Akt and beta-Catenin-TCF/Lef Signaling Pathways
    • DOI 10.1158/0008-5472.CAN-03-0666
    • Xie D, Yin D, Tong X et al (2004) Cyr61 is overexpressed in gliomas and involved in integrin-linked kinase-mediated Akt and beta-catenin-TCF/Lef signaling pathways. Cancer Res 64:1987-1996 (Pubitemid 38339444)
    • (2004) Cancer Research , vol.64 , Issue.6 , pp. 1987-1996
    • Xie, D.1    Yin, D.2    Tong, X.3    O'Kelly, J.4    Mori, A.5    Miller, C.6    Black, K.7    Gui, D.8    Said, J.W.9    Koeffler, H.P.10
  • 92
    • 0344412950 scopus 로고    scopus 로고
    • Expression of Tenascin-C in Various Human Brain Tumors and its Relevance for Survival in Patients with Astrocytoma
    • DOI 10.1002/cncr.11796
    • Leins A, Riva P, Lindstedt R et al (2003) Expression of tenascin-C in various human brain tumors and its relevance for survival in patients with astrocytoma. Cancer 98:2430-9. doi:10.1002/cncr.11796 (Pubitemid 37466658)
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2430-2439
    • Leins, A.1    Riva, P.2    Lindstedt, R.3    Davidoff, M.S.4    Mehraein, P.5    Weis, S.6
  • 93
    • 0028888390 scopus 로고
    • Tenascin expression in astrocytomas correlates with angiogenesis
    • Zagzag D, Friedlander DR, Miller DC et al (1995) Tenascin expression in astrocytomas correlates with angiogenesis. Cancer Res 55:907-14
    • (1995) Cancer Res , vol.55 , pp. 907-914
    • Zagzag, D.1    Friedlander, D.R.2    Miller, D.C.3
  • 95
    • 0027256757 scopus 로고
    • Expression of tenascin in human gliomas: Its relation to histological malignancy, tumor dedifferentiation and angiogenesis
    • HiguchiM, Ohnishi T, AritaN et al (1993) Expression of tenascin in human gliomas: its relation to histological malignancy, tumor dedifferentiation and angiogenesis. Acta Neuropathologica 85:481-7 (Pubitemid 23180409)
    • (1993) Acta Neuropathologica , vol.85 , Issue.5 , pp. 481-487
    • Higuchi, M.1    Ohnishi, T.2    Arita, N.3    Hiraga, S.4    Hayakawa, T.5
  • 97
    • 33846253207 scopus 로고    scopus 로고
    • Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12
    • DOI 10.1158/0008-5472.CAN-05-0470
    • Sarkar S, Nuttall RK, Liu S et al (2006) Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12. Cancer Res 66:11771-80. doi:10.1158/0008-5472.CAN-05-0470 (Pubitemid 46094189)
    • (2006) Cancer Research , vol.66 , Issue.24 , pp. 11771-11780
    • Sarkar, S.1    Nuttall, R.K.2    Liu, S.3    Edwards, D.R.4    Yong, V.W.5
  • 98
    • 0030007495 scopus 로고    scopus 로고
    • Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin
    • Deryugina EI, Bourdon MA (1996) Tenascin mediates human glioma cell migration and modulates cell migration on fibronectin. J Cell Sci 109(Pt 3):643-52 (Pubitemid 26092685)
    • (1996) Journal of Cell Science , vol.109 , Issue.3 , pp. 643-652
    • Deryugina, E.I.1    Bourdon, M.A.2
  • 100
    • 51449095317 scopus 로고    scopus 로고
    • Role of galectin-1 in migration and invasion of human glioblastoma multiforme cell lines
    • doi:10.3171/JNS/2008/109/8/0273
    • Jung TY, Jung S, Ryu HH et al (2008) Role of galectin-1 in migration and invasion of human glioblastoma multiforme cell lines. J Neurosurg 109:273-284. doi:10.3171/JNS/2008/109/8/0273
    • (2008) J Neurosurg , vol.109 , pp. 273-284
    • Jung, T.Y.1    Jung, S.2    Ryu, H.H.3
  • 102
    • 84860801440 scopus 로고    scopus 로고
    • Galectin-1, a gene preferentially expressed at the tumormargin, promotes glioblastoma cell invasion
    • doi:10.1186/1476-4598-11-32
    • Toussaint LG, Nilson AE, Goble JM et al (2012) Galectin-1, a gene preferentially expressed at the tumormargin, promotes glioblastoma cell invasion. Mol Cancer 11:32. doi:10.1186/1476-4598-11-32
    • (2012) Mol Cancer , vol.11 , pp. 32
    • Toussaint, L.G.1    Nilson, A.E.2    Goble, J.M.3
  • 104
    • 0035194504 scopus 로고    scopus 로고
    • Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration
    • Zurich, Switzerland
    • Camby I, Belot N, Rorive S et al (2001) Galectins are differentially expressed in supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas, and significantly modulate tumor astrocyte migration. Brain Pathol (Zurich, Switzerland) 11:12-26
    • (2001) Brain Pathol , vol.11 , pp. 12-26
    • Camby, I.1    Belot, N.2    Rorive, S.3
  • 105
    • 43249107550 scopus 로고    scopus 로고
    • Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses
    • doi:10.1097/NEN.0b013e318170f892
    • Le Mercier M, Mathieu V, Haibe-Kains B et al (2008) Knocking down galectin 1 in human hs683 glioblastoma cells impairs both angiogenesis and endoplasmic reticulum stress responses. J Neuropathol Exp Neurol 67:456 - 69. doi:10.1097/NEN.0b013e318170f892
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 456-469
    • Le Mercier, M.1    Mathieu, V.2    Haibe-Kains, B.3
  • 109
    • 0030872450 scopus 로고    scopus 로고
    • Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system
    • DOI 10.1002/(SICI)1097-0142(19970815)80:4<776
    • Bresalier RS, Yan PS, Byrd JC et al (1997) Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system. Cancer 80:776-87 (Pubitemid 27339834)
    • (1997) Cancer , vol.80 , Issue.4 , pp. 776-787
    • Bresalier, R.S.1    Yan, P.-S.2    Byrd, J.C.3    Lotan, R.4    Raz, A.5
  • 111
    • 1642576134 scopus 로고    scopus 로고
    • Correlation of Osteopontin Protein Expression and Pathological Stage across a Wide Variety of Tumor Histologies
    • DOI 10.1158/1078-0432.CCR-1405-2
    • Coppola D, Szabo M, Boulware D et al (2004) Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies. Clin Cancer Res Off J Am Assoc Cancer Res 10:184-90 (Pubitemid 38114178)
    • (2004) Clinical Cancer Research , vol.10 , Issue.1 I , pp. 184-190
    • Coppola, D.1    Szabo, M.2    Boulware, D.3    Muraca, P.4    Alsarraj, M.5    Chambers, A.F.6    Yeatman, T.J.7
  • 112
    • 0028798116 scopus 로고
    • Expression of osteopontin in human glioma. Its correlation with the malignancy. Laboratory investigation
    • Saitoh Y, Kuratsu J, Takeshima H et al (1995) Expression of osteopontin in human glioma. Its correlation with the malignancy. Laboratory investigation. J Tech Methods Pathol 72:55-63
    • (1995) J Tech Methods Pathol , vol.72 , pp. 55-63
    • Saitoh, Y.1    Kuratsu, J.2    Takeshima, H.3
  • 113
    • 33646594731 scopus 로고    scopus 로고
    • Identification of genes differentially expressed in glioblastoma versus pilocytic astrocytoma using suppression subtractive hybridization
    • doi:10.1038/sj.onc.1209305
    • Colin C, Baeza N, Bartoli C et al (2006) Identification of genes differentially expressed in glioblastoma versus pilocytic astrocytoma using suppression subtractive hybridization. Oncogene 25:2818-26. doi:10.1038/sj.onc. 1209305
    • (2006) Oncogene , vol.25 , pp. 2818-2826
    • Colin, C.1    Baeza, N.2    Bartoli, C.3
  • 114
    • 84868022009 scopus 로고    scopus 로고
    • Osteopontin increases heme oxygenase-1 expression and subsequently induces cell migration and invasion in glioma cells
    • doi:10.1093/neuonc/nos262
    • Lu D-Y, Yeh W-L, Huang S-M et al (2012) Osteopontin increases heme oxygenase-1 expression and subsequently induces cell migration and invasion in glioma cells. Neuro-Oncol 14:1367-78. doi:10.1093/neuonc/nos262
    • (2012) Neuro-Oncol , vol.14 , pp. 1367-1378
    • Lu, D.-Y.1    Yeh, W.-L.2    Huang, S.-M.3
  • 115
    • 75749153239 scopus 로고    scopus 로고
    • Osteopontin regulates human glioma cell invasiveness and tumor growth in mice
    • doi:10.1093/neuonc/nop013
    • Jan HJ, Lee CC, Shih YL et al (2010) Osteopontin regulates human glioma cell invasiveness and tumor growth in mice. Neuro Oncol 12:58-70. doi:10.1093/neuonc/nop013
    • (2010) Neuro Oncol , vol.12 , pp. 58-70
    • Jan, H.J.1    Lee, C.C.2    Shih, Y.L.3
  • 116
    • 0034757822 scopus 로고    scopus 로고
    • SPARC modulates cell growth, attachment and migration of U87 glioma cells on brain extracellular matrix proteins
    • DOI 10.1023/A:1012201300188
    • Rempel SA, Golembieski WA, Fisher JL et al (2001) SPARC modulates cell growth, attachment and migration of U87 glioma cells on brain extracellular matrix proteins. J Neuro-Oncol 53:149-60 (Pubitemid 33034688)
    • (2001) Journal of Neuro-Oncology , vol.53 , Issue.2 , pp. 149-160
    • Rempel, S.A.1    Golembieski, W.A.2    Fisher, J.L.3    Maile, M.4    Nakeff, A.5
  • 117
    • 0036829855 scopus 로고    scopus 로고
    • Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo
    • Schultz C, Lemke N, Ge S et al (2002) Secreted protein acidic and rich in cysteine promotes glioma invasion and delays tumor growth in vivo. Cancer Res 62:6270-7 (Pubitemid 35244481)
    • (2002) Cancer Research , vol.62 , Issue.21 , pp. 6270-6277
    • Schultz, C.1    Lemke, N.2    Ge, S.3    Golembieski, W.A.4    Rempel, S.A.5
  • 118
    • 34948821611 scopus 로고    scopus 로고
    • SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA
    • Kunigal S, Gondi CS, Gujrati M et al (2006) SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA. Int J Oncol 29:1349-57
    • (2006) Int J Oncol , vol.29 , pp. 1349-1357
    • Kunigal, S.1    Gondi, C.S.2    Gujrati, M.3
  • 119
    • 64549154509 scopus 로고    scopus 로고
    • Downregulation of SPARC expression inhibits cell migration and invasion in malignant gliomas
    • Seno T, Harada H, Kohno S et al (2009) Downregulation of SPARC expression inhibits cell migration and invasion in malignant gliomas. Int J Oncol 34:707-15
    • (2009) Int J Oncol , vol.34 , pp. 707-715
    • Seno, T.1    Harada, H.2    Kohno, S.3
  • 120
    • 34248219058 scopus 로고    scopus 로고
    • SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells
    • DOI 10.1016/j.neulet.2007.04.037, PII S030439400700479X
    • McClung HM, Thomas SL, Osenkowski P et al (2007) SPARC upregulates MT1-MMP expression, MMP-2 activation, and the secretion and cleavage of galectin-3 in U87MG glioma cells. Neurosci Lett 419:172-7. doi:10.1016/j.neulet. 2007.04.037 (Pubitemid 46719671)
    • (2007) Neuroscience Letters , vol.419 , Issue.2 , pp. 172-177
    • McClung, H.M.1    Thomas, S.L.2    Osenkowski, P.3    Toth, M.4    Menon, P.5    Raz, A.6    Fridman, R.7    Rempel, S.A.8
  • 122
    • 84876004117 scopus 로고    scopus 로고
    • Stromal protein periostin identified as a progression associated and prognostic biomarker in glioma via inducing an invasive and proliferative phenotype
    • doi:10.3892/ijo.2013.1847
    • Wang H, Wang Y, Jiang C (2013) Stromal protein periostin identified as a progression associated and prognostic biomarker in glioma via inducing an invasive and proliferative phenotype. Int J Oncol 42:1716-1724. doi:10.3892/ijo.2013.1847
    • (2013) Int J Oncol , vol.42 , pp. 1716-1724
    • Wang, H.1    Wang, Y.2    Jiang, C.3
  • 123
    • 17844367105 scopus 로고    scopus 로고
    • Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery
    • discussion 390
    • Bello L, Francolini M, Marthyn P et al (2001) Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery. Neurosurg 49:380-9, discussion 390
    • (2001) Neurosurg , vol.49 , pp. 380-389
    • Bello, L.1    Francolini, M.2    Marthyn, P.3
  • 124
    • 2642533612 scopus 로고    scopus 로고
    • Integrin beta3 Overexpression Suppresses Tumor Growth in a Human Model of Gliomagenesis: Implications for the Role of beta3 Overexpression in Glioblastoma Multiforme
    • DOI 10.1158/0008-5472.CAN-03-3354
    • Kanamori M, Vanden Berg SR, Bergers G et al (2004) Integrin beta3 overexpression suppresses tumor growth in a humanmodel of gliomagenesis: implications for the role of beta3 overexpression in glioblastoma multiforme. Cancer Res 64:2751-2758 (Pubitemid 38500612)
    • (2004) Cancer Research , vol.64 , Issue.8 , pp. 2751-2758
    • Kanamori, M.1    Vanden, B.S.R.2    Bergers, G.3    Berger, M.S.4    Pieper, R.O.5
  • 125
    • 77954924659 scopus 로고    scopus 로고
    • Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma
    • doi:10.1200/JCO.2009.26.6650
    • Stupp R, Hegi ME, Neyns B et al (2010) Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol Off J Am Soc Clin Oncol 28:2712-8. doi:10.1200/JCO.2009.26.6650
    • (2010) J Clin Oncol off J Am Soc Clin Oncol , vol.28 , pp. 2712-2718
    • Stupp, R.1    Hegi, M.E.2    Neyns, B.3
  • 126
    • 84874435875 scopus 로고    scopus 로고
    • αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion
    • doi:10.1091/mbc.E12-07-0521
    • Reyes SB, Narayanan AS, Lee HS et al (2013) αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion. Mol Biol Cell 24:474-82. doi:10.1091/mbc.E12-07-0521
    • (2013) Mol Biol Cell , vol.24 , pp. 474-482
    • Reyes, S.B.1    Narayanan, A.S.2    Lee, H.S.3
  • 127
    • 80054044019 scopus 로고    scopus 로고
    • Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by β8 integrin
    • doi:10.1158/0008-5472.CAN-11-0991
    • Tchaicha JH, Reyes SB, Shin J et al (2011) Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by β8 integrin. Cancer Res 71:6371-81. doi:10.1158/0008-5472.CAN-11-0991
    • (2011) Cancer Res , vol.71 , pp. 6371-6381
    • Tchaicha, J.H.1    Reyes, S.B.2    Shin, J.3
  • 128
    • 84879685041 scopus 로고    scopus 로고
    • Integrin α3 is overexpressed in glioma stem-like cells and promotes invasion
    • doi:10.1038/bjc.2013.218
    • Nakada M, Nambu E, Furuyama N et al (2013) Integrin α3 is overexpressed in glioma stem-like cells and promotes invasion. Br J Cancer. doi:10.1038/bjc.2013.218
    • (2013) Br J Cancer
    • Nakada, M.1    Nambu, E.2    Furuyama, N.3
  • 129
    • 44849109087 scopus 로고    scopus 로고
    • Fascin expresion in glial tumors and its prognostic significance in glioblastomas
    • DOI 10.1111/j.1440-1789.2008.00889.x
    • Gunal A, Onguru O, Safali M, Beyzadeoglu M (2008) Fascin expression [corrected] in glial tumors and its prognostic significance in glioblastomas. Neuropathol 28:382-386. doi:10.1111/j.1440-1789.2008.00889 (Pubitemid 351798976)
    • (2008) Neuropathology , vol.28 , Issue.4 , pp. 382-386
    • Gunal, A.1    Onguru, O.2    Safali, M.3    Beyzadeoglu, M.4
  • 131
    • 27944500223 scopus 로고    scopus 로고
    • Fascin expression in 90 patients with glioblastomamultiforme
    • doi:10.1016/j.anndiagpath.2005.07.005
    • Roma AA, PraysonRA (2005) Fascin expression in 90 patients with glioblastomamultiforme. Ann Diagn Pathol 9:307-11. doi:10.1016/j.anndiagpath. 2005.07.005
    • (2005) Ann Diagn Pathol , vol.9 , pp. 307-311
    • Roma, A.A.1    Prayson, R.A.2
  • 132
    • 39049136505 scopus 로고    scopus 로고
    • The role of fascin in the migration and invasiveness of malignant glioma cells
    • DOI 10.1593/neo.07909
    • Hwang JH, Smith CA, Salhia B, Rutka JT (2008) The role of fascin in the migration and invasiveness of malignant glioma cells. Neoplasia 10:149-159 (Pubitemid 351240881)
    • (2008) Neoplasia , vol.10 , Issue.2 , pp. 149-159
    • Jeong, H.H.1    Smith, C.A.2    Salhia, B.3    Rutka, J.T.4
  • 133
    • 0033638445 scopus 로고    scopus 로고
    • Ezrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas
    • Geiger KD, Stoldt P, Schlote W, Derouiche A (2000) Ezrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas.AmJ Pathol 157:1785-1793
    • (2000) AmJ Pathol , vol.157 , pp. 1785-1793
    • Geiger, K.D.1    Stoldt, P.2    Schlote, W.3    Derouiche, A.4
  • 136
    • 77957787559 scopus 로고    scopus 로고
    • Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase
    • doi:10.1074/jbc.M110.120451
    • Li X, Lee AY (2010) Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase. J Biol Chem 285:32436-32445. doi:10.1074/jbc.M110.120451
    • (2010) J Biol Chem , vol.285 , pp. 32436-32445
    • Li, X.1    Lee, A.Y.2
  • 137
    • 84856529410 scopus 로고    scopus 로고
    • Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton
    • Li X, Law JW, Lee AY (2011) Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton. Oncogene 31(5):595-610
    • (2011) Oncogene , vol.31 , Issue.5 , pp. 595-610
    • Li, X.1    Law, J.W.2    Lee, A.Y.3
  • 138
    • 84861559660 scopus 로고    scopus 로고
    • Effects of SEMA3G on migration and invasion of glioma cells
    • doi:10.3892/or.2012.1796
    • Zhou X, Ma L, Li J et al (2012) Effects of SEMA3G on migration and invasion of glioma cells. Oncol Rep 28:269-75. doi:10.3892/or.2012.1796
    • (2012) Oncol Rep , vol.28 , pp. 269-275
    • Zhou, X.1    Ma, L.2    Li, J.3
  • 139
    • 1342289507 scopus 로고    scopus 로고
    • Increased invasive capacity of connexin43-overexpressing malignant glioma cells
    • Zhang W, Nwagwu C, Le DM et al (2003) Increased invasive capacity of connexin43-overexpressing malignant glioma cells. J Neurosurg 99:1039-1046. doi:10.3171/jns.2003.99.6.1039 (Pubitemid 44717400)
    • (2003) Journal of Neurosurgery , vol.99 , Issue.6 , pp. 1039-1046
    • Zhang, W.1    Nwagwu, C.2    Le, D.M.3    Yong, V.W.4    Song, H.5    Couldwell, W.T.6
  • 140
    • 84867854600 scopus 로고    scopus 로고
    • Down-regulation of connexin43 expression reveals the involvement of caveolin-1 containing lipid rafts in human U251 glioblastoma cell invasion
    • doi:10.1002/mc.20853
    • Strale PO, Clarhaut J, Lamiche C et al (2012) Down-regulation of connexin43 expression reveals the involvement of caveolin-1 containing lipid rafts in human U251 glioblastoma cell invasion. Mol Carcinog 51:845-860. doi:10.1002/mc.20853
    • (2012) Mol Carcinog , vol.51 , pp. 845-860
    • Strale, P.O.1    Clarhaut, J.2    Lamiche, C.3
  • 141
    • 84875521067 scopus 로고    scopus 로고
    • The role of drebrin in glioma migration and invasion
    • doi:10.1016/j.yexcr.2012.11.008
    • Terakawa Y, Agnihotri S, Golbourn B et al (2013) The role of drebrin in glioma migration and invasion. Exp Cell Res 319:517-528. doi:10.1016/j.yexcr. 2012.11.008
    • (2013) Exp Cell Res , vol.319 , pp. 517-528
    • Terakawa, Y.1    Agnihotri, S.2    Golbourn, B.3
  • 142
    • 72449128177 scopus 로고    scopus 로고
    • Fibulin-3 is uniquely upregulated in malignant gliomas and promotes tumor cell motility and invasion
    • doi:10.1158/1541-7786.MCR-09-0207
    • Hu B, Thirtamara-Rajamani KK, Sim H, Viapiano MS (2009) Fibulin-3 is uniquely upregulated in malignant gliomas and promotes tumor cell motility and invasion. Mol Cancer Res 7:1756-1770. doi:10.1158/1541-7786.MCR-09-0207
    • (2009) Mol Cancer Res , vol.7 , pp. 1756-1770
    • Hu, B.1    Thirtamara-Rajamani, K.K.2    Sim, H.3    Viapiano, M.S.4
  • 143
    • 84868613149 scopus 로고    scopus 로고
    • NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma
    • SperanzaMC, Frattini V, Pisati F et al (2012) NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma. Oncotarget 3:723-734
    • (2012) Oncotarget , vol.3 , pp. 723-734
    • Speranza, M.C.1    Frattini, V.2    Pisati, F.3
  • 144
    • 84885446637 scopus 로고    scopus 로고
    • Gab2 expression in glioma and its implications for tumor invasion
    • doi:10.3109/0284186X.2012.750032
    • Shi L, SunX, Zhang J et al (2012) Gab2 expression in glioma and its implications for tumor invasion. Acta Oncol. doi:10.3109/0284186X.2012.750032
    • (2012) Acta Oncol
    • Shi, L.1    Sun, X.2    Zhang, J.3
  • 145
    • 84863783538 scopus 로고    scopus 로고
    • Silencing of Eps8 blocksmigration and invasion in human glioblastoma cell lines
    • doi:10.1016/j.yexcr.2012.05.010
    • Cattaneo MG, Cappellini E, Vicentini LM (2012) Silencing of Eps8 blocksmigration and invasion in human glioblastoma cell lines. Exp Cell Res 318:1901-1912. doi:10.1016/j.yexcr.2012.05.010
    • (2012) Exp Cell Res , vol.318 , pp. 1901-1912
    • Cattaneo, M.G.1    Cappellini, E.2    Vicentini, L.M.3
  • 146
    • 34547138438 scopus 로고    scopus 로고
    • Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24
    • DOI 10.1074/jbc.M609567200
    • Fukushima T, Tezuka T, Shimomura T et al (2007) Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24. J Biol Chem 282:18634-18644. doi:10.1074/jbc.M609567200 (Pubitemid 47100243)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.25 , pp. 18634-18644
    • Fukushima, T.1    Tezuka, T.2    Shimomura, T.3    Nakano, S.4    Kataoka, H.5
  • 147
    • 33744920862 scopus 로고    scopus 로고
    • An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility
    • DOI 10.1074/jbc.M513686200
    • Wang GK, Hu L, Fuller GN, Zhang W (2006) An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility. J Biol Chem 281:14085-91. doi:10.1074/jbc.M513686200 (Pubitemid 43848335)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.20 , pp. 14085-14091
    • Wang, G.K.1    Hu, L.2    Fuller, G.N.3    Zhang, W.4
  • 148
    • 0034544537 scopus 로고    scopus 로고
    • Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques
    • Sallinen SL, Sallinen PK, Haapasalo HK et al (2000) Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques. Cancer Res 60:6617-22
    • (2000) Cancer Res , vol.60 , pp. 6617-6622
    • Sallinen, S.L.1    Sallinen, P.K.2    Haapasalo, H.K.3
  • 149
    • 70349628642 scopus 로고    scopus 로고
    • Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas
    • doi:10.1215/15228517-2008-114
    • Lin Y, Jiang T, Zhou K et al (2009) Plasma IGFBP-2 levels predict clinical outcomes of patients with high-grade gliomas. Neuro Oncol 11:468-476. doi:10.1215/15228517-2008-114
    • (2009) Neuro Oncol , vol.11 , pp. 468-476
    • Lin, Y.1    Jiang, T.2    Zhou, K.3
  • 152
    • 34247866468 scopus 로고    scopus 로고
    • IQGAP1 and IGFBP2: Valuable biomarkers for determining prognosis in glioma patients
    • doi:10.1097/nen.0b013e31804567d7 00005072-200705000-00010
    • McDonald KL, O'Sullivan MG, Parkinson JF et al (2007) IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients. J Neuropathol Exp Neurol 66:405-417. doi:10.1097/nen.0b013e31804567d7 00005072-200705000-00010
    • (2007) J Neuropathol Exp Neurol , vol.66 , pp. 405-417
    • McDonald, K.L.1    O'Sullivan, M.G.2    Parkinson, J.F.3
  • 153
    • 0035046403 scopus 로고    scopus 로고
    • In vivo expression of insulin-like growth factor-binding protein-2 in human gliomas increases with the tumor grade
    • DOI 10.1210/en.142.4.1652
    • Elmlinger MW, Deininger MH, Schuett BS et al (2001) In vivo expression of insulin-like growth factor-binding protein-2 in human gliomas increases with the tumor grade. Endocrinology 142:1652-8 (Pubitemid 32299696)
    • (2001) Endocrinology , vol.142 , Issue.4 , pp. 1652-1658
    • Elmlinger, M.W.1    Deininger, M.H.2    Schuett, B.S.3    Meyermann, R.4    Duffner, F.5    Grote, E.H.6    Ranke, M.B.7
  • 154
    • 0345133277 scopus 로고    scopus 로고
    • IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion
    • doi:10.1073/pnas.2332186100 2332186100 [pii]
    • Song SW, Fuller GN, Khan A et al (2003) IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion. Proc Natl Acad Sci U S A 100:13970 -13975. doi:10.1073/pnas.2332186100 2332186100 [pii]
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13970-13975
    • Song, S.W.1    Fuller, G.N.2    Khan, A.3
  • 155
    • 18144374855 scopus 로고    scopus 로고
    • Inactivation of the invasion inhibitory gene IIp45 by alternative splicing in gliomas
    • DOI 10.1158/0008-5472.CAN-04-3392
    • Song SW, Fuller GN, Zheng H, ZhangW(2005) Inactivation of the invasion inhibitory gene IIp45 by alternative splicing in gliomas. Cancer Res 65:3562-3567. doi:10.1158/0008-5472.CAN-04-3392 (Pubitemid 40616331)
    • (2005) Cancer Research , vol.65 , Issue.9 , pp. 3562-3567
    • Song, S.W.1    Fuller, G.N.2    Zheng, H.3    Zhang, W.4
  • 156
    • 59149105836 scopus 로고    scopus 로고
    • ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway
    • doi:10.1158/0008-5472.CAN-08-2110
    • Hu B, Shi B, Jarzynka MJ et al (2009) ADP-ribosylation factor 6 regulates glioma cell invasion through the IQ-domain GTPase-activating protein 1-Rac1-mediated pathway. Cancer Res 69:794-801. doi:10.1158/0008-5472.CAN-08- 2110
    • (2009) Cancer Res , vol.69 , pp. 794-801
    • Hu, B.1    Shi, B.2    Jarzynka, M.J.3
  • 157
    • 79960433425 scopus 로고    scopus 로고
    • Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2
    • doi:10.1074/jbc.M110.178012
    • Suvasini R, Shruti B, Thota B et al (2011) Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase (PI3K/MAPK) pathways by modulating IGF-2. J Biol Chem 286:25882-25890. doi:10.1074/jbc.M110. 178012
    • (2011) J Biol Chem , vol.286 , pp. 25882-25890
    • Suvasini, R.1    Shruti, B.2    Thota, B.3
  • 158
    • 79952433556 scopus 로고    scopus 로고
    • A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion
    • doi:10.1371/journal.pone.0017649
    • Gopal U, Bohonowych JE, Lema-Tome C et al (2011) A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion. PloS One 6:e17649. doi:10.1371/journal.pone.0017649
    • (2011) PloS One , vol.6
    • Gopal, U.1    Bohonowych, J.E.2    Lema-Tome, C.3
  • 159
    • 84866437189 scopus 로고    scopus 로고
    • 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion
    • doi:10.3892/or.2012.1996
    • Miekus K, Kijowski J, Sekuła M, Majka M (2012) 17AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. Oncol Rep 28:1903-9. doi:10.3892/or.2012.1996
    • (2012) Oncol Rep , vol.28 , pp. 1903-1909
    • Miekus, K.1    Kijowski, J.2    Sekuła, M.3    Majka, M.4
  • 160
    • 70149107047 scopus 로고    scopus 로고
    • A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion
    • doi:10.1158/0008-5472.CAN-09-0886
    • Lo HW, Zhu H, Cao X et al (2009) A novel splice variant of GLI1 that promotes glioblastoma cell migration and invasion. Cancer Res 69:6790-6798. doi:10.1158/0008-5472.CAN-09-0886
    • (2009) Cancer Res , vol.69 , pp. 6790-6798
    • Lo, H.W.1    Zhu, H.2    Cao, X.3
  • 161
    • 82255163003 scopus 로고    scopus 로고
    • Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcome
    • doi:10.1002/ijc.26049
    • Guan H, Cai J, Zhang N et al (2012) Sp1 is upregulated in human glioma, promotes MMP-2-mediated cell invasion and predicts poor clinical outcome. Int J Cancer J Int Cancer 130:593-601. doi:10.1002/ijc.26049
    • (2012) Int J Cancer J Int Cancer , vol.130 , pp. 593-601
    • Guan, H.1    Cai, J.2    Zhang, N.3
  • 162
    • 78650183431 scopus 로고    scopus 로고
    • STAT5 regulates glioma cell invasion by pathways dependent and independent of STAT5 DNA binding
    • doi:10.1016/j.neulet.2010.10.028
    • Cao S, Wang C, Zheng Q et al (2011) STAT5 regulates glioma cell invasion by pathways dependent and independent of STAT5 DNA binding. Neurosci Lett 487:228-33. doi:10.1016/j.neulet.2010.10.028
    • (2011) Neurosci Lett , vol.487 , pp. 228-233
    • Cao, S.1    Wang, C.2    Zheng, Q.3
  • 163
    • 79956227340 scopus 로고    scopus 로고
    • STAT6 expression in glioblastoma promotes invasive growth
    • doi:10.1186/1471-2407-11-184
    • Merk BC, Owens JL, Lopes M-BS et al (2011) STAT6 expression in glioblastoma promotes invasive growth. BMC Cancer 11:184. doi:10.1186/1471-2407- 11-184
    • (2011) BMC Cancer , vol.11 , pp. 184
    • Merk, B.C.1    Owens, J.L.2    Lopes, M.-B.S.3
  • 164
    • 84861405117 scopus 로고    scopus 로고
    • ZFP36 expression impairs glioblastoma cell lines viability and invasiveness by targeting multiple signal transduction pathways
    • doi:10.4161/cc.20309
    • Selmi T, Martello A, Vignudelli T et al (2012) ZFP36 expression impairs glioblastoma cell lines viability and invasiveness by targeting multiple signal transduction pathways. Cell Cycle 11:1977-87. doi:10.4161/cc.20309
    • (2012) Cell Cycle , vol.11 , pp. 1977-1987
    • Selmi, T.1    Martello, A.2    Vignudelli, T.3
  • 165
    • 77954674187 scopus 로고    scopus 로고
    • TWIST1 promotes invasion through mesenchymal change in human glioblastoma
    • doi:10.1186/1476-4598-9-194
    • Mikheeva SA, Mikheev AM, Petit A et al (2010) TWIST1 promotes invasion through mesenchymal change in human glioblastoma. Mol Cancer 9:194. doi:10.1186/1476-4598-9-194
    • (2010) Mol Cancer , vol.9 , pp. 194
    • Mikheeva, S.A.1    Mikheev, A.M.2    Petit, A.3
  • 166
    • 33644873765 scopus 로고    scopus 로고
    • TWIST is expressed in human gliomas and promotes invasion
    • Elias MC, Tozer KR, Silber JR et al (2005) TWIST is expressed in human gliomas and promotes invasion. Neoplasia 7:824-837
    • (2005) Neoplasia , vol.7 , pp. 824-837
    • Elias, M.C.1    Tozer, K.R.2    Silber, J.R.3
  • 167
    • 79954575702 scopus 로고    scopus 로고
    • Frizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial intracranial transplantation
    • doi:10.1158/0008-5472.CAN-10-1495
    • Jin X, Jeon H-Y, Joo KM et al (2011) Frizzled 4 regulates stemness and invasiveness of migrating glioma cells established by serial intracranial transplantation. Cancer Res 71:3066-75. doi:10.1158/0008-5472.CAN-10-1495
    • (2011) Cancer Res , vol.71 , pp. 3066-3075
    • Jin, X.1    Jeon, H.-Y.2    Joo, K.M.3
  • 169
    • 4444257383 scopus 로고    scopus 로고
    • Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas
    • Gutenberg A, Bruck W, Buchfelder M, Ludwig HC (2004) Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas. Acta Neuropathol 108:224-230. doi:10.1007/s00401-004-0886-3 (Pubitemid 39199514)
    • (2004) Acta Neuropathologica , vol.108 , Issue.3 , pp. 224-230
    • Gutenberg, A.1    Bruck, W.2    Buchfelder, M.3    Ludwig, H.C.4
  • 170
    • 53349127325 scopus 로고    scopus 로고
    • Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts
    • doi:10.1007/s11060-008-9656-8
    • Lipinski CA, Tran NL, Viso C et al (2008) Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts. J Neurooncol 90:181-189. doi:10.1007/s11060-008-9656-8
    • (2008) J Neurooncol , vol.90 , pp. 181-189
    • Lipinski, C.A.1    Tran, N.L.2    Viso, C.3
  • 171
    • 84857064430 scopus 로고    scopus 로고
    • Knockdown of cyclin D1 inhibits proliferation, induces apoptosis, and attenuates the invasive capacity of human glioblastoma cells
    • doi:10.1007/s11060-011-0692-4
    • Wang J, Wang Q, Cui Y et al (2012) Knockdown of cyclin D1 inhibits proliferation, induces apoptosis, and attenuates the invasive capacity of human glioblastoma cells. J Neurooncol 106:473-484. doi:10.1007/s11060-011-0692-4
    • (2012) J Neurooncol , vol.106 , pp. 473-484
    • Wang, J.1    Wang, Q.2    Cui, Y.3
  • 172
    • 85027928456 scopus 로고    scopus 로고
    • Overexpression of SASH1 related to the decreased invasion ability of human glioma U251 cells
    • doi:10.1007/s13277-012-0487-z
    • Yang L, LiuM, Gu Z et al (2012) Overexpression of SASH1 related to the decreased invasion ability of human glioma U251 cells. Tumour Biol 33:2255-2263. doi:10.1007/s13277-012-0487-z
    • (2012) Tumour Biol , vol.33 , pp. 2255-2263
    • Yang, L.1    Liu, M.2    Gu, Z.3
  • 173
    • 84864721664 scopus 로고    scopus 로고
    • RNAi-mediated inhibition of presenilin 2 inhibits glioma cell growth and invasion and is involved in the regulation of Nrg1/ErbB signaling
    • doi:10.1093/neuonc/nos138
    • Liu B, Wang L, Shen LL et al (2012) RNAi-mediated inhibition of presenilin 2 inhibits glioma cell growth and invasion and is involved in the regulation of Nrg1/ErbB signaling. Neuro Oncol 14:994-1006. doi:10.1093/neuonc/ nos138
    • (2012) Neuro Oncol , vol.14 , pp. 994-1006
    • Liu, B.1    Wang, L.2    Shen, L.L.3
  • 174
    • 84862744838 scopus 로고    scopus 로고
    • ZEB2mediatesmultiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma
    • doi:10.1371/journal.pone.0038842
    • Qi S, SongY, PengYet al (2012) ZEB2mediatesmultiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma. PLoS One 7:e38842. doi:10.1371/journal.pone.0038842
    • (2012) PLoS One , vol.7
    • Qi, S.1    Song, Y.P.A.2
  • 175
    • 80055106066 scopus 로고    scopus 로고
    • Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
    • doi:10.1371/journal.pone.0026740
    • Alonso MM, Diez-Valle R, Manterola L et al (2011) Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. PLoS One 6:e26740. doi:10.1371/journal.pone.0026740
    • (2011) PLoS One , vol.6
    • Alonso, M.M.1    Diez-Valle, R.2    Manterola, L.3
  • 176
    • 84863317139 scopus 로고    scopus 로고
    • Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling
    • doi:10.1111/j.1349-7006.2012.02291.x
    • Xu L, ZhuY, Xu J et al (2012) Notch1 activation promotes renal cell carcinoma growth via PI3K/Akt signaling. Cancer Sci 103:1253-8. doi:10.1111/j.1349-7006.2012.02291.x
    • (2012) Cancer Sci , vol.103 , pp. 1253-1258
    • Xu, L.1    Zhu, Y.2    Xu, J.3
  • 177
    • 80054089654 scopus 로고    scopus 로고
    • Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch-1 receptor
    • doi:10.1186/1476-4598-10-130
    • Raghu H, Gondi CS, Dinh DH et al (2011) Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch-1 receptor. Mol Cancer 10:130. doi:10.1186/1476-4598-10-130
    • (2011) Mol Cancer , vol.10 , pp. 130
    • Raghu, H.1    Gondi, C.S.2    Dinh, D.H.3
  • 178
    • 84863926995 scopus 로고    scopus 로고
    • Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-kappaB activation
    • doi:10.1091/mbc.E11-09-0805
    • Tao T, Cheng C, Ji Y et al (2012) Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-kappaB activation. Mol Biol Cell 23:2635 -2644. doi:10.1091/mbc.E11-09-0805
    • (2012) Mol Biol Cell , vol.23 , pp. 2635-2644
    • Tao, T.1    Cheng, C.2    Ji, Y.3
  • 179
    • 84885187547 scopus 로고    scopus 로고
    • The role of Nrf2 in migration and invasion of human glioma cell U251
    • doi:10.1016/j.wneu.2011.06.063
    • Pan H, Wang H, Zhu L et al (2011) The role of Nrf2 in migration and invasion of human glioma cell U251.World Neurosurg. doi:10.1016/j.wneu.2011.06. 063
    • (2011) World Neurosurg
    • Pan, H.1    Wang, H.2    Zhu, L.3
  • 180
    • 84864352060 scopus 로고    scopus 로고
    • BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro
    • doi:10.1007/s00432-012-1172-8
    • Bai J, Mei P-J, Liu H et al (2012) BRG1 expression is increased in human glioma and controls glioma cell proliferation, migration and invasion in vitro. J Cancer Res Clin Oncol 138:991-8. doi:10.1007/s00432-012-1172-8
    • (2012) J Cancer Res Clin Oncol , vol.138 , pp. 991-998
    • Bai, J.1    Mei, P.-J.2    Liu, H.3
  • 181
    • 84874112354 scopus 로고    scopus 로고
    • Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme
    • doi:10.1038/onc.2012.104
    • Wang Y, Moncayo G, Morin P Jr et al (2013) Mer receptor tyrosine kinase promotes invasion and survival in glioblastoma multiforme. Oncogene 32:872-882. doi:10.1038/onc.2012.104
    • (2013) Oncogene , vol.32 , pp. 872-882
    • Wang, Y.1    Moncayo, G.2    Morin Jr., P.3
  • 182
    • 84862893179 scopus 로고    scopus 로고
    • Silencing of IKKε using siRNA inhibits proliferation and invasion of glioma cells in vitro and in vivo
    • doi:10.3892/ijo.2012.1452
    • Li H, Chen L, Zhang A et al (2012) Silencing of IKKε using siRNA inhibits proliferation and invasion of glioma cells in vitro and in vivo. Int J Oncol 41:169-78. doi:10.3892/ijo.2012.1452
    • (2012) Int J Oncol , vol.41 , pp. 169-178
    • Li, H.1    Chen, L.2    Zhang, A.3
  • 183
    • 83255193930 scopus 로고    scopus 로고
    • The catalytic phosphoinositol 3-kinase isoform p110δ is required for glioma cell migration and invasion
    • doi:10.1016/j.ejca.2011.09.006
    • Luk SK, Piekorz RP, Nürnberg B, Tony To S-S (2012) The catalytic phosphoinositol 3-kinase isoform p110δ is required for glioma cell migration and invasion. Eur J Cancer 48:149-57. doi:10.1016/j.ejca.2011.09.006
    • (2012) Eur J Cancer , vol.48 , pp. 149-157
    • Luk, S.K.1    Piekorz, R.P.2    Nürnberg, B.3    Tony To, S.-S.4
  • 184
    • 84861523133 scopus 로고    scopus 로고
    • Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion
    • doi:10.1038/onc.2011.436
    • Feng H, Liu KW, Guo P et al (2012) Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion. Oncogene 31:2691-702. doi:10.1038/onc.2011.436
    • (2012) Oncogene , vol.31 , pp. 2691-2702
    • Feng, H.1    Liu, K.W.2    Guo, P.3
  • 185
    • 84865972612 scopus 로고    scopus 로고
    • The small GTPase RhoG mediates glioblastoma cell invasion
    • doi:10.1186/1476-4598-11-65
    • Kwiatkowska A, Didier S, Fortin S et al (2012) The small GTPase RhoG mediates glioblastoma cell invasion. Mol Cancer 11:65. doi:10.1186/1476-4598-11- 65
    • (2012) Mol Cancer , vol.11 , pp. 65
    • Kwiatkowska, A.1    Didier, S.2    Fortin, S.3
  • 186
    • 84857052322 scopus 로고    scopus 로고
    • HMGA1 expression in human gliomas and its correlation with tumor proliferation, invasion and angiogenesis
    • doi:10.1007/s11060-011-0710-6
    • Pang B, Fan H, Zhang IYet al (2012)HMGA1 expression in human gliomas and its correlation with tumor proliferation, invasion and angiogenesis. J Neuro-Oncol 106:543-9. doi:10.1007/s11060-011-0710-6
    • (2012) J Neuro-Oncol , vol.106 , pp. 543-549
    • Pang, B.1    Fan, H.Z.I.A.2
  • 187
    • 84855565289 scopus 로고    scopus 로고
    • Oct-3/4 promotes migration and invasion of glioblastoma cells
    • doi:10.1002/jcb.23374
    • Kobayashi K, Takahashi H, Inoue A et al (2012) Oct-3/4 promotes migration and invasion of glioblastoma cells. J Cell Biochem 113:508-17. doi:10.1002/jcb.23374
    • (2012) J Cell Biochem , vol.113 , pp. 508-517
    • Kobayashi, K.1    Takahashi, H.2    Inoue, A.3
  • 188
    • 70149096641 scopus 로고    scopus 로고
    • Proteolytic cleavage of protein tyrosine phosphatase mu regulates glioblastoma cell migration
    • doi:10.1158/0008-5472.CAN-09-0863
    • Burgoyne AM, Phillips-Mason PJ, Burden-Gulley SM et al (2009) Proteolytic cleavage of protein tyrosine phosphatase mu regulates glioblastoma cell migration. Cancer Res 69:6960-8. doi:10.1158/0008-5472.CAN-09-0863
    • (2009) Cancer Res , vol.69 , pp. 6960-6968
    • Burgoyne, A.M.1    Phillips-Mason, P.J.2    Burden-Gulley, S.M.3
  • 189
    • 70449650636 scopus 로고    scopus 로고
    • PTPmu suppresses glioma cell migration and dispersal
    • doi:10.1215/15228517-2009-019
    • Burgoyne AM, Palomo JM, Phillips-Mason PJ et al (2009) PTPmu suppresses glioma cell migration and dispersal. Neuro-Oncol 11:767-78. doi:10.1215/ 15228517-2009-019
    • (2009) Neuro-Oncol , vol.11 , pp. 767-778
    • Burgoyne, A.M.1    Palomo, J.M.2    Phillips-Mason, P.J.3
  • 190
    • 84857109002 scopus 로고    scopus 로고
    • miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ
    • doi:10.1038/onc.2011.280
    • Quintavalle C, Garofalo M, Zanca C et al (2012) miR-221/222 overexpession in human glioblastoma increases invasiveness by targeting the protein phosphate PTPμ. Oncogene 31:858-68. doi:10.1038/onc.2011.280
    • (2012) Oncogene , vol.31 , pp. 858-868
    • Quintavalle, C.1    Garofalo, M.2    Zanca, C.3
  • 191
    • 78149478057 scopus 로고    scopus 로고
    • MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib
    • doi:10.1093/neuonc/noq017
    • Chahal M, Xu Y, Lesniak D et al (2010) MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. Neuro-Oncol 12:822-33. doi:10.1093/neuonc/noq017
    • (2010) Neuro-Oncol , vol.12 , pp. 822-833
    • Chahal, M.1    Xu, Y.2    Lesniak, D.3
  • 192
    • 80052709229 scopus 로고    scopus 로고
    • Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation
    • doi:10.1093/neuonc/nor084
    • Azoitei N, Kleger A, Schoo N et al (2011) Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation. Neuro-Oncol 13:710-24. doi:10.1093/neuonc/nor084
    • (2011) Neuro-Oncol , vol.13 , pp. 710-724
    • Azoitei, N.1    Kleger, A.2    Schoo, N.3
  • 193
    • 84879883626 scopus 로고    scopus 로고
    • Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro
    • Bernhart E, Damm S, Wintersperger A et al (2013) Protein kinase D2 regulates migration and invasion of U87MG glioblastoma cells in vitro. Exp Cell Res 319(13):2037-2048
    • (2013) Exp Cell Res , vol.319 , Issue.13 , pp. 2037-2048
    • Bernhart, E.1    Damm, S.2    Wintersperger, A.3
  • 194
    • 84876334224 scopus 로고    scopus 로고
    • GOLPH3 regulates the migration and invasion of glioma cells though RhoA
    • doi:10.1016/j.bbrc.2013.03.003
    • Zhou X, Zhan W, Bian W et al (2013) GOLPH3 regulates the migration and invasion of glioma cells though RhoA. Biochem Biophys Res Commun 433:338-44. doi:10.1016/j.bbrc.2013.03.003
    • (2013) Biochem Biophys Res Commun , vol.433 , pp. 338-344
    • Zhou, X.1    Zhan, W.2    Bian, W.3
  • 195
    • 82955167835 scopus 로고    scopus 로고
    • Expression of the Golgi phosphoprotein-3 gene in human gliomas: A pilot study
    • doi:10.1007/s11060-011-0573-x
    • Li X-Y, Liu W, Chen S-F et al (2011) Expression of the Golgi phosphoprotein-3 gene in human gliomas: a pilot study. J Neuro-Oncol 105:159-63. doi:10.1007/s11060-011-0573-x
    • (2011) J Neuro-Oncol , vol.105 , pp. 159-163
    • Li, X.-Y.1    Liu, W.2    Chen, S.-F.3
  • 196
    • 84867885906 scopus 로고    scopus 로고
    • Overexpression of Golgi phosphoprotein-3 (GOLPH3) in glioblastoma multiforme is associated with worse prognosis
    • doi:10.1007/s11060-012-0970-9
    • Zhou J, Xu T, Qin R et al (2012) Overexpression of Golgi phosphoprotein-3 (GOLPH3) in glioblastoma multiforme is associated with worse prognosis. J Neuro-Oncol 110:195-203. doi:10.1007/s11060-012-0970-9
    • (2012) J Neuro-Oncol , vol.110 , pp. 195-203
    • Zhou, J.1    Xu, T.2    Qin, R.3
  • 197
    • 84879083010 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 alters glioma inflammatory and invasive properties
    • doi:10.1007/s11060-013-1109-3
    • Tarassishin L, Lee SC (2013) Interferon regulatory factor 3 alters glioma inflammatory and invasive properties. J Neurooncol. doi:10.1007/s11060-013- 1109-3
    • (2013) J Neurooncol
    • Tarassishin, L.1    Lee, S.C.2
  • 198
    • 84874354425 scopus 로고    scopus 로고
    • Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survival
    • doi:10.1371/journal.pone.0057793
    • Huber RM, Rajski M, Sivasankaran B et al (2013) Deltex-1 activates mitotic signaling and proliferation and increases the clonogenic and invasive potential of U373 and LN18 glioblastoma cells and correlates with patient survival. PloS One 8:e57793. doi:10.1371/journal.pone.0057793
    • (2013) PloS One , vol.8
    • Huber, R.M.1    Rajski, M.2    Sivasankaran, B.3
  • 199
    • 33745071151 scopus 로고    scopus 로고
    • Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma
    • doi:10.1186/1471-2407-6-97
    • Liang Y, Bollen AW, Aldape KD, Gupta N (2006) Nuclear FABP7 immunoreactivity is preferentially expressed in infiltrative glioma and is associated with poor prognosis in EGFR-overexpressing glioblastoma. BMC Cancer 6:97. doi:10.1186/1471-2407-6-97
    • (2006) BMC Cancer , vol.6 , pp. 97
    • Liang, Y.1    Bollen, A.W.2    Aldape, K.D.3    Gupta, N.4
  • 200
    • 84859235771 scopus 로고    scopus 로고
    • Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines
    • doi:10.1371/journal.pone.0033031
    • De Stefano D, Tommonaro G, Malik SA et al (2012) Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines. PloS One 7:e33031. doi:10.1371/journal.pone.0033031
    • (2012) PloS One , vol.7
    • De Stefano, D.1    Tommonaro, G.2    Malik, S.A.3
  • 203
    • 33748997415 scopus 로고    scopus 로고
    • Ephrin-B3 ligand promotes glioma invasion through activation of Rac1
    • DOI 10.1158/0008-5472.CAN-05-4211
    • Nakada M, Drake KL, Nakada S et al (2006) Ephrin-B3 ligand promotes glioma invasion through activation of Rac1. Cancer Res 66:8492-500. doi:10.1158/0008-5472.CAN-05-4211 (Pubitemid 44449162)
    • (2006) Cancer Research , vol.66 , Issue.17 , pp. 8492-8500
    • Nakada, M.1    Drake, K.L.2    Nakada, S.3    Niska, J.A.4    Berens, M.E.5
  • 204
    • 2342577589 scopus 로고    scopus 로고
    • The Phosphorylation of EphB2 Receptor Regulates Migration and Invasion of Human Glioma Cells
    • DOI 10.1158/0008-5472.CAN-03-3667
    • Nakada M, Niska JA, Miyamori H et al (2004) The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells. Cancer Res 64:3179-3185 (Pubitemid 38581420)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3179-3185
    • Nakada, M.1    Niska, J.A.2    Miyamori, H.3    McDonough, W.S.4    Wu, J.5    Sato, H.6    Berens, M.E.7
  • 205
    • 27644466229 scopus 로고    scopus 로고
    • EphA2 as a novel molecular marker and target in glioblastoma multiforme
    • DOI 10.1158/1541-7786.MCR-05-0056
    • Wykosky J, Gibo DM, Stanton C, Debinski W (2005) EphA2 as a novel molecular marker and target in glioblastoma multiforme. Mol Cancer Res 3:541-551. doi:10.1158/1541-7786.MCR-05-0056 (Pubitemid 41567273)
    • (2005) Molecular Cancer Research , vol.3 , Issue.10 , pp. 541-551
    • Wykosky, J.1    Gibo, D.M.2    Stanton, C.3    Debinski, W.4
  • 207
    • 84873813207 scopus 로고    scopus 로고
    • Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMPresponse element-binding protein
    • doi:10.1074/jbc.M112.397398
    • Shimizu A, Nakayama H, Wang P et al (2013) Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMPresponse element-binding protein. J Biol Chem 288:2210-22. doi:10.1074/jbc.M112.397398
    • (2013) J Biol Chem , vol.288 , pp. 2210-2222
    • Shimizu, A.1    Nakayama, H.2    Wang, P.3
  • 208
    • 84879997845 scopus 로고    scopus 로고
    • Netrin-1 induced activation of Notch signaling mediates glioblastoma cell invasion
    • doi:10.1242/jcs.120022
    • Ylivinkka I, Hu Y, Chen P et al (2013) Netrin-1 induced activation of Notch signaling mediates glioblastoma cell invasion. J Cell Sci. doi:10.1242/jcs.120022
    • (2013) J Cell Sci
    • Ylivinkka, I.1    Hu, Y.2    Chen, P.3
  • 209
    • 84876115150 scopus 로고    scopus 로고
    • Bex2 is critical for migration and invasion inmalignant glioma cells
    • doi:10.1007/s12031-012-9864-8
    • Zhou X, Xu X, Meng Q et al (2013) Bex2 is critical for migration and invasion inmalignant glioma cells. JMol Neurosci:MN 50:78-87. doi:10.1007/s12031-012-9864-8
    • (2013) JMol Neurosci:MN , vol.50 , pp. 78-87
    • Zhou, X.1    Xu, X.2    Meng, Q.3
  • 212
    • 84875510616 scopus 로고    scopus 로고
    • Overexpression of CD99 increases the migration and invasiveness of humanmalignant glioma cells
    • doi:10.1177/1947601912473603
    • Seol HJ, Chang JH, Yamamoto J et al (2012) Overexpression of CD99 increases the migration and invasiveness of humanmalignant glioma cells. Genes Cancer 3:535-549. doi:10.1177/1947601912473603
    • (2012) Genes Cancer , vol.3 , pp. 535-549
    • Seol, H.J.1    Chang, J.H.2    Yamamoto, J.3
  • 213
    • 0033851302 scopus 로고    scopus 로고
    • Expression of EMMPRIN (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas
    • doi:10.1002/1097-0215(20001001)88
    • Sameshima T, Nabeshima K, Toole BP et al (2000) Expression of EMMPRIN (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas. Int J Cancer 88:21-27. doi:10.1002/1097-0215(20001001)88
    • (2000) Int J Cancer , vol.88 , pp. 21-27
    • Sameshima, T.1    Nabeshima, K.2    Toole, B.P.3
  • 214
    • 25144509494 scopus 로고    scopus 로고
    • Inhibition of basigin expression in glioblastoma cell line via antisense RNA reduces tumor cell invasion and angiogenesis
    • Liang Q, Xiong H, Gao G et al (2005) Inhibition of basigin expression in glioblastoma cell line via antisense RNA reduces tumor cell invasion and angiogenesis. Cancer Biol Ther 4:759-762 (Pubitemid 41351176)
    • (2005) Cancer Biology and Therapy , vol.4 , Issue.7 , pp. 759-762
    • Liang, Q.1    Xiong, H.2    Gao, G.3    Xiong, K.4    Wang, X.5    Zhao, Z.6    Zhang, H.7    Li, Y.8
  • 215
    • 67349256425 scopus 로고    scopus 로고
    • Clinical implications and prognostic value of EMMPRIN/CD147 and MMP2 expression in pediatric gliomas
    • doi:10.1007/s00431-008-0828-5
    • Gu J, Zhang C, Chen R et al (2009) Clinical implications and prognostic value of EMMPRIN/CD147 and MMP2 expression in pediatric gliomas. Eur J Pediatr 168:705-10. doi:10.1007/s00431-008-0828-5
    • (2009) Eur J Pediatr , vol.168 , pp. 705-710
    • Gu, J.1    Zhang, C.2    Chen, R.3
  • 216
    • 25444448993 scopus 로고    scopus 로고
    • Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
    • DOI 10.1158/0008-5472.CAN-05-1204
    • Bredel M, Bredel C, Juric D et al (2005) Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. Cancer Res 65:8679-8689. doi:10.1158/0008-5472.CAN-05- 1204 (Pubitemid 41377355)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8679-8689
    • Bredel, M.1    Bredel, C.2    Juric, D.3    Harsh, G.R.4    Vogel, H.5    Recht, L.D.6    Sikic, B.I.7
  • 217
    • 0037137847 scopus 로고    scopus 로고
    • CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase
    • DOI 10.1002/ijc.1605
    • Kohno M, Hasegawa H, Miyake M et al (2002) CD151 enhances cell motility and metastasis of cancer cells in the presence of focal adhesion kinase. Int J Cancer 97:336-343. doi:10.1002/ijc.1605 [pii] (Pubitemid 34049024)
    • (2002) International Journal of Cancer , vol.97 , Issue.3 , pp. 336-343
    • Kohno, M.1    Hasegawa, H.2    Miyake, M.3    Yamamoto, T.4    Fujita, S.5
  • 218
    • 79953711715 scopus 로고    scopus 로고
    • Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity
    • doi:10.1007/s11060-010-0323-5
    • Enloe BM, Jay DG (2011) Inhibition of Necl-5 (CD155/PVR) reduces glioblastoma dispersal and decreases MMP-2 expression and activity. J Neurooncol 102:225-235. doi:10.1007/s11060-010-0323-5
    • (2011) J Neurooncol , vol.102 , pp. 225-235
    • Enloe, B.M.1    Jay, D.G.2
  • 219
    • 28244458116 scopus 로고    scopus 로고
    • CD155/PVR enhances glioma cell dispersal by regulating adhesion signaling and focal adhesion dynamics
    • DOI 10.1158/0008-5472.CAN-05-1890
    • Sloan KE, Stewart JK, Treloar AF et al (2005) CD155/PVR enhances glioma cell dispersal by regulating adhesion signaling and focal adhesion dynamics. Cancer Res 65:10930-7. doi:10.1158/0008-5472.CAN-05-1890 (Pubitemid 41713361)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10930-10937
    • Sloan, K.E.1    Stewart, J.K.2    Treloar, A.F.3    Matthews, R.T.4    Jay, D.G.5
  • 220
    • 84857182500 scopus 로고    scopus 로고
    • Receptors for hyaluronic acid and poliovirus: A combinatorial role in glioma invasion?
    • doi:10.1371/journal.pone.0030691
    • Maherally Z, Smith JR, An Q, Pilkington GJ (2012) Receptors for hyaluronic acid and poliovirus: a combinatorial role in glioma invasion? PloS One 7:e30691. doi:10.1371/journal.pone.0030691
    • (2012) PloS One , vol.7
    • Maherally, Z.1    Smith, J.R.2    An, Q.3    Pilkington, G.J.4
  • 221
    • 84866946180 scopus 로고    scopus 로고
    • CD166/activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion
    • doi:10.1093/neuonc/nor202
    • Kijima N, Hosen N, Kagawa N et al (2012) CD166/activated leukocyte cell adhesion molecule is expressed on glioblastoma progenitor cells and involved in the regulation of tumor cell invasion. Neuro Oncol 14:1254-1264. doi:10.1093/neuonc/nor202
    • (2012) Neuro Oncol , vol.14 , pp. 1254-1264
    • Kijima, N.1    Hosen, N.2    Kagawa, N.3
  • 222
    • 0032456173 scopus 로고    scopus 로고
    • Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors
    • Tews DS, Nissen A (1998-1999) Expression of adhesion factors and degrading proteins in primary and secondary glioblastomas and their precursor tumors. Invasion Metastasis 18(5-6):271-284 (Pubitemid 30223703)
    • (1998) Invasion and Metastasis , vol.18 , Issue.5-6 , pp. 271-284
    • Tews, D.S.1    Nissen, A.2
  • 223
    • 0032525219 scopus 로고    scopus 로고
    • Expression of the neural cell adhesion molecule in astrocytic tumors: An inverse correlation with malignancy
    • DOI 10.1002/(SICI)1097-0142(19980515)82:10<1921
    • Sasaki H, Yoshida K, Ikeda E et al (1998) Expression of the neural cell adhesion molecule in astrocytic tumors: an inverse correlation with malignancy. Cancer 82:1921-31 (Pubitemid 28208649)
    • (1998) Cancer , vol.82 , Issue.10 , pp. 1921-1931
    • Sasaki, H.1    Yoshida, K.2    Ikeda, E.3    Asou, H.4    Inaba, M.5    Otani, M.6    Kawase, T.7
  • 224
    • 79954437964 scopus 로고    scopus 로고
    • Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases
    • doi:10.1007/s00432-010-0888-6
    • Duenisch P, Reichart R, Mueller U et al (2011) Neural cell adhesion molecule isoform 140 declines with rise of WHO grade in human gliomas and serves as indicator for the invasion zone of multiform glioblastomas and brain metastases. J Cancer Res Clin Oncol 137:399-414. doi:10.1007/s00432-010-0888-6
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 399-414
    • Duenisch, P.1    Reichart, R.2    Mueller, U.3
  • 230
    • 77949453545 scopus 로고    scopus 로고
    • Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines
    • doi:10.1186/1471-2407-10-91
    • Amoureux M-C, Coulibaly B, Chinot O et al (2010) Polysialic acid neural cell adhesion molecule (PSA-NCAM) is an adverse prognosis factor in glioblastoma, and regulates olig2 expression in glioma cell lines. BMC Cancer 10:91. doi:10.1186/1471-2407-10-91
    • (2010) BMC Cancer , vol.10 , pp. 91
    • Amoureux, M.-C.1    Coulibaly, B.2    Chinot, O.3
  • 231
    • 34447625239 scopus 로고    scopus 로고
    • Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: Correlation of nestin with prognosis of patient survival
    • doi:10.1016/j.surneu.2006.10.050, discussion 143-4
    • Strojnik T, Røsland GV, Sakariassen PO et al (2007) Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival. Surg Neurol 68:133-43. doi:10.1016/j.surneu.2006.10.050, discussion 143-4
    • (2007) Surg Neurol , vol.68 , pp. 133-143
    • Strojnik, T.1    Røsland, G.V.2    Sakariassen, P.O.3
  • 232
    • 60149107175 scopus 로고    scopus 로고
    • Nestin and CD133: Valuable stem cell-specific markers for determining clinical outcome of glioma patients
    • doi:10.1186/1756-9966-27-85
    • ZhangM, Song T, Yang L et al (2008) Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients. J Exp Clin Cancer Res: CR 27:85. doi:10.1186/1756-9966-27-85
    • (2008) J Exp Clin Cancer Res: CR , vol.27 , pp. 85
    • Zhang, M.1    Song, T.2    Yang, L.3
  • 233
    • 79955813838 scopus 로고    scopus 로고
    • Neuroepithelial stemcellmarker nestin regulates themigration, invasion and growth of human gliomas
    • doi:10.3892/or.2011.1267
    • Ishiwata T, Teduka K, Yamamoto T et al (2011) Neuroepithelial stemcellmarker nestin regulates themigration, invasion and growth of human gliomas. Oncol Rep 26:91-9. doi:10.3892/or.2011.1267
    • (2011) Oncol Rep , vol.26 , pp. 91-99
    • Ishiwata, T.1    Teduka, K.2    Yamamoto, T.3
  • 234
    • 33646259475 scopus 로고    scopus 로고
    • Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression
    • doi:10.1007/s00401-006-0063-y
    • Mishima K, Kato Y, Kaneko MK et al (2006) Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression. Acta Neuropathol 111:483-488. doi:10.1007/s00401-006- 0063-y
    • (2006) Acta Neuropathol , vol.111 , pp. 483-488
    • Mishima, K.1    Kato, Y.2    Kaneko, M.K.3
  • 235
    • 84859534661 scopus 로고    scopus 로고
    • Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation
    • doi:10.1093/neuonc/nos055
    • Peterziel H, Müller J, Danner A et al (2012) Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation. Neuro-Oncology 14:426-39. doi:10.1093/neuonc/nos055
    • (2012) Neuro-Oncology , vol.14 , pp. 426-439
    • Peterziel, H.1    Müller, J.2    Danner, A.3
  • 236
    • 77957902680 scopus 로고    scopus 로고
    • miR-29b and miR-125a regulate podoplanin and suppress invasion in glioblastoma
    • doi:10.1002/gcc.20808
    • Cortez MA, Nicoloso MS, Shimizu M et al (2010) miR-29b and miR-125a regulate podoplanin and suppress invasion in glioblastoma. Genes Chromosomes Cancer 49:981-90. doi:10.1002/gcc.20808
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 981-990
    • Cortez, M.A.1    Nicoloso, M.S.2    Shimizu, M.3
  • 237
    • 33749605467 scopus 로고    scopus 로고
    • Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction
    • DOI 10.1002/ijc.22108
    • Van den Boom J, Wolter M, Blaschke B et al (2006) Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcriptionpolymerase chain reaction. Int J Cancer 119:2330-2338. doi:10.1002/ijc.22108 (Pubitemid 44546952)
    • (2006) International Journal of Cancer , vol.119 , Issue.10 , pp. 2330-2338
    • Van Den, B.J.1    Wolter, M.2    Blaschke, B.3    Knobbe, C.B.4    Reifenberger, G.5
  • 238
    • 79959796807 scopus 로고    scopus 로고
    • alpha-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of betacatenin transactivation
    • doi:10.1007/s11060-010-0413-4
    • Ji H, Wang J, Fang B et al (2011) alpha-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of betacatenin transactivation. J Neurooncol 103:445-451. doi:10.1007/s11060-010-0413-4
    • (2011) J Neurooncol , vol.103 , pp. 445-451
    • Ji, H.1    Wang, J.2    Fang, B.3
  • 239
    • 78650936018 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma agonist pioglitazone inhibits beta-catenin-mediated glioma cell growth and invasion
    • doi:10.1007/s11010-010-0637-9
    • Wan Z, Shi W, Shao B et al (2011) Peroxisome proliferator-activated receptor gamma agonist pioglitazone inhibits beta-catenin-mediated glioma cell growth and invasion. Mol Cell Biochem 349:1-10. doi:10.1007/s11010-010-0637-9
    • (2011) Mol Cell Biochem , vol.349 , pp. 1-10
    • Wan, Z.1    Shi, W.2    Shao, B.3
  • 240
    • 84876228770 scopus 로고    scopus 로고
    • Knockdown of FRAT1 expression by RNA interference inhibits human glioblastoma cell growth, migration and invasion
    • doi:10.1371/journal.pone.0061206
    • Guo G, Kuai D, Cai S et al (2013) Knockdown of FRAT1 expression by RNA interference inhibits human glioblastoma cell growth, migration and invasion. PloS One 8:e61206. doi:10.1371/journal.pone.0061206
    • (2013) PloS One , vol.8
    • Guo, G.1    Kuai, D.2    Cai, S.3
  • 241
    • 84876232000 scopus 로고    scopus 로고
    • Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-gamma and STAT3 protein signaling pathways
    • doi:10.1074/jbc.A112.393900
    • Ou Y, Ma L, Dong L et al (2013) Migfilin protein promotes migration and invasion in human glioma through epidermal growth factor receptor-mediated phospholipase C-gamma and STAT3 protein signaling pathways. J Biol Chem 288:10948. doi:10.1074/jbc.A112.393900
    • (2013) J Biol Chem , vol.288 , pp. 10948
    • Ou, Y.1    Ma, L.2    Dong, L.3
  • 242
    • 34250340883 scopus 로고    scopus 로고
    • Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration
    • DOI 10.1002/ijc.22679
    • Eckerich C, Zapf S, Fillbrandt R et al (2007) Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration. Int J Cancer J Int Cancer 121:276-83. doi:10.1002/ijc.22679 (Pubitemid 46917695)
    • (2007) International Journal of Cancer , vol.121 , Issue.2 , pp. 276-283
    • Eckerich, C.1    Zapf, S.2    Fillbrandt, R.3    Loges, S.4    Westphal, M.5    Lamszus, K.6
  • 243
    • 79959971880 scopus 로고    scopus 로고
    • c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
    • doi:10.1073/pnas.1016912108
    • Li Y, Li A, Glas M et al (2011) c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype. Proc Natl Acad Sci U S A 108:9951-6. doi:10.1073/pnas.1016912108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 9951-9956
    • Li, Y.1    Li, A.2    Glas, M.3
  • 245
    • 79957987225 scopus 로고    scopus 로고
    • Tie2/TEK modulates the interaction of glioma and brain tumor stem cells with endothelial cells and promotes an invasive phenotype
    • Liu D, Martin V, Fueyo J et al (2010) Tie2/TEK modulates the interaction of glioma and brain tumor stem cells with endothelial cells and promotes an invasive phenotype. Oncotarget 1:700-9
    • (2010) Oncotarget , vol.1 , pp. 700-709
    • Liu, D.1    Martin, V.2    Fueyo, J.3
  • 248
    • 0041806539 scopus 로고    scopus 로고
    • Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2
    • doi:10.1073/pnas.1533394100
    • Hu B, Guo P, Fang Q et al (2003) Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2. Proc Natl Acad Sci U S A 100:8904 - 9. doi:10.1073/pnas.1533394100
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 8904-8909
    • Hu, B.1    Guo, P.2    Fang, Q.3
  • 249
    • 77957288028 scopus 로고    scopus 로고
    • Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma
    • doi:10.1073/pnas.0914072107
    • Auf G, Jabouille A, Guérit S et al (2010) Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Proc Natl Acad Sci U S A 107:15553-8. doi:10.1073/pnas.0914072107
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15553-15558
    • Auf, G.1    Jabouille, A.2    Guérit, S.3
  • 250
    • 0034213146 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor 1alpha in brain tumors: Association with angiogenesis, invasion, and progression
    • DOI 10.1002/1097-0142(20000601)88:11<2606::AID
    • Zagzag D, Zhong H, Scalzitti JM et al (2000) Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88:2606-18 (Pubitemid 30331970)
    • (2000) Cancer , vol.88 , Issue.11 , pp. 2606-2618
    • Zagzag, D.1    Zhong, H.2    Scalzitti, J.M.3    Laughner, E.4    Simons, J.W.5    Semenza, G.L.6
  • 251
    • 77952863838 scopus 로고    scopus 로고
    • Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres
    • doi:10.1186/1476-4598-9-133
    • Méndez O, Zavadil J, EsencayM et al (2010) Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Mol Cancer 9:133. doi:10.1186/1476-4598-9-133
    • (2010) Mol Cancer , vol.9 , pp. 133
    • Méndez, O.1    Zavadil, J.2    Esencay, M.3
  • 252
    • 34247847903 scopus 로고    scopus 로고
    • Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment inmalignant gliomas
    • Fujiwara S, Nakagawa K, Harada H et al (2007) Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment inmalignant gliomas. Int J Oncol 30:793-802
    • (2007) Int J Oncol , vol.30 , pp. 793-802
    • Fujiwara, S.1    Nakagawa, K.2    Harada, H.3
  • 253
    • 84879693403 scopus 로고    scopus 로고
    • Effect of silencing HIF-1α on proliferation, invasion and migration of glioblastoma U87 cells
    • doi:10.1007/s10072-012-1010-4
    • Shen SH, Kwan AL, Chen YY, Wang ZX (2013) Effect of silencing HIF-1α on proliferation, invasion and migration of glioblastoma U87 cells. Neurol Sci Off J Ital Neurol Soc Ital Soc Clin Neurophysiol 34:365-71. doi:10.1007/s10072-012-1010-4
    • (2013) Neurol Sci off J Ital Neurol Soc Ital Soc Clin Neurophysiol , vol.34 , pp. 365-371
    • Shen, S.H.1    Kwan, A.L.2    Chen, Y.Y.3    Wang, Z.X.4
  • 254
    • 70350099256 scopus 로고    scopus 로고
    • Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers
    • doi:10.1186/1476-4598-8-71
    • Dreyfuss JM, Johnson MD, Park PJ (2009) Meta-analysis of glioblastoma multiforme versus anaplastic astrocytoma identifies robust gene markers. Mol Cancer 8:71. doi:10.1186/1476-4598-8-71
    • (2009) Mol Cancer , vol.8 , pp. 71
    • Dreyfuss, J.M.1    Johnson, M.D.2    Park, P.J.3
  • 256
    • 84885080490 scopus 로고    scopus 로고
    • Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion
    • doi:10.1007/s11060-013-1081-y
    • Zhou X, Liu Z, Shi Q et al (2013) Geranylgeranyltransferase I regulates HIF-1α promoting glioblastoma cell migration and invasion. J Neurooncol 112:365-74. doi:10.1007/s11060-013-1081-y
    • (2013) J Neurooncol , vol.112 , pp. 365-374
    • Zhou, X.1    Liu, Z.2    Shi, Q.3
  • 257
    • 58249120108 scopus 로고    scopus 로고
    • Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo
    • 4p following 86
    • Kolesnikova TV, Kazarov AR, Lemieux ME et al (2009) Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo. Neoplasia 11:77-86, 4p following 86
    • (2009) Neoplasia , vol.11 , pp. 77-86
    • Kolesnikova, T.V.1    Kazarov, A.R.2    Lemieux, M.E.3
  • 260
    • 78649640148 scopus 로고    scopus 로고
    • TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling
    • doi:10.1158/1541-7786.MCR-10-0334
    • Paulino VM, Yang Z, Kloss J et al (2010) TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling. Mol Cancer Res 8:1558-1567. doi:10.1158/1541-7786.MCR-10-0334
    • (2010) Mol Cancer Res , vol.8 , pp. 1558-1567
    • Paulino, V.M.1    Yang, Z.2    Kloss, J.3
  • 261
    • 84864011846 scopus 로고    scopus 로고
    • Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells
    • doi:10.1158/1541-7786.MCR-11-0616
    • Fortin SP, Ennis MJ, Schumacher CA et al (2012) Cdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cells. Mol Cancer Res 10:958-968. doi:10.1158/1541- 7786.MCR-11-0616
    • (2012) Mol Cancer Res , vol.10 , pp. 958-968
    • Fortin, S.P.1    Ennis, M.J.2    Schumacher, C.A.3
  • 262
    • 84875683676 scopus 로고    scopus 로고
    • TNF receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells
    • doi:10.1007/s11010-013-1573-2
    • Peng Z, Shuangzhu Y, Yongjie J et al (2013) TNF receptor-associated factor 6 regulates proliferation, apoptosis, and invasion of glioma cells. Mol Cell Biochem 377:87-96. doi:10.1007/s11010-013-1573-2
    • (2013) Mol Cell Biochem , vol.377 , pp. 87-96
    • Peng, Z.1    Shuangzhu, Y.2    Yongjie, J.3
  • 263
    • 33750565442 scopus 로고    scopus 로고
    • Protein disulfide isomerase expression is related to the invasive properties of malignant glioma
    • DOI 10.1158/0008-5472.CAN-05-4589
    • Goplen D, Wang J, Enger PO et al (2006) Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Res 66:9895-9902. doi:10.1158/0008-5472.CAN-05-4589 (Pubitemid 44672041)
    • (2006) Cancer Research , vol.66 , Issue.20 , pp. 9895-9902
    • Goplen, D.1    Wang, J.2    Enger, P.O.3    Tysnes, B.B.4    Terzis, A.J.A.5    Laerum, O.D.6    Bjerkvig, R.7
  • 264
    • 82955161628 scopus 로고    scopus 로고
    • Epidermal growth factor module-containing mucin-like receptor 2 is a newly identified adhesion G protein-coupled receptor associated with poor overall survival and an invasive phenotype in glioblastoma
    • doi:10.1007/s11060-011-0576-7
    • Rutkowski MJ, Sughrue ME, Kane AJ et al (2011) Epidermal growth factor module-containing mucin-like receptor 2 is a newly identified adhesion G protein-coupled receptor associated with poor overall survival and an invasive phenotype in glioblastoma. J Neurooncol. doi:10.1007/s11060-011-0576-7
    • (2011) J Neurooncol
    • Rutkowski, M.J.1    Sughrue, M.E.2    Kane, A.J.3
  • 265
    • 78049288580 scopus 로고    scopus 로고
    • EMR-3: A potential mediator of invasive phenotypic variation in glioblastoma and novel therapeutic target
    • doi:10.1097/WNR.0b013e32833f19f2
    • Kane AJ, Sughrue ME, Rutkowski MJ et al (2010) EMR-3: a potential mediator of invasive phenotypic variation in glioblastoma and novel therapeutic target. Neurorep 21:1018-22. doi:10.1097/WNR.0b013e32833f19f2
    • (2010) Neurorep , vol.21 , pp. 1018-1022
    • Kane, A.J.1    Sughrue, M.E.2    Rutkowski, M.J.3
  • 266
    • 84859364857 scopus 로고    scopus 로고
    • Novel report of expression and function of CD97 in malignant gliomas: Correlation withWilms tumor 1 expression and glioma cell invasiveness
    • doi:10.3171/2011.11.JNS111455
    • Chidambaram A, Fillmore HL, Van Meter TE et al (2012) Novel report of expression and function of CD97 in malignant gliomas: correlation withWilms tumor 1 expression and glioma cell invasiveness. J Neurosurg 116:843-853. doi:10.3171/2011.11.JNS111455
    • (2012) J Neurosurg , vol.116 , pp. 843-853
    • Chidambaram, A.1    Fillmore, H.L.2    Van Meter, T.E.3
  • 267
    • 84876869343 scopus 로고    scopus 로고
    • Overexpression of CD97 confers an invasive phenotype in glioblastoma cells and is associated with decreased survival of glioblastoma patients
    • doi:10.1371/journal.pone.0062765
    • Safaee M, Clark AJ, Oh MC et al (2013) Overexpression of CD97 confers an invasive phenotype in glioblastoma cells and is associated with decreased survival of glioblastoma patients. PLoS One 8:e62765. doi:10.1371/journal.pone. 0062765
    • (2013) PLoS One , vol.8
    • Safaee, M.1    Clark, A.J.2    Oh, M.C.3
  • 268
    • 47749135194 scopus 로고    scopus 로고
    • Receptor "hijacking" by malignant glioma cells: A tactic for tumor progression
    • doi:10.1016/j.canlet.2008.03.014
    • Huang J, Chen K, Gong W et al (2008) Receptor "hijacking" by malignant glioma cells: a tactic for tumor progression. Cancer Lett 267:254-261. doi:10.1016/j.canlet.2008.03.014
    • (2008) Cancer Lett , vol.267 , pp. 254-261
    • Huang, J.1    Chen, K.2    Gong, W.3
  • 270
    • 37249035649 scopus 로고    scopus 로고
    • Production of angiogenic factors by human glioblastoma cells following activation of the Gprotein coupled formylpeptide receptor FPR
    • doi:10.1007/s11060-007-9443-y
    • Yao XH, Ping YF, Chen JH et al (2008) Production of angiogenic factors by human glioblastoma cells following activation of the Gprotein coupled formylpeptide receptor FPR. J Neurooncol 86:47-53. doi:10.1007/s11060-007-9443-y
    • (2008) J Neurooncol , vol.86 , pp. 47-53
    • Yao, X.H.1    Ping, Y.F.2    Chen, J.H.3
  • 271
    • 77949540049 scopus 로고    scopus 로고
    • The G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells
    • doi:10.1038/sj.bjc.6605591
    • Huang J, Chen K, Chen J et al (2010) The G-protein-coupled formylpeptide receptor FPR confers a more invasive phenotype on human glioblastoma cells. Br J Cancer 102:1052-1060. doi:10.1038/sj.bjc.6605591
    • (2010) Br J Cancer , vol.102 , pp. 1052-1060
    • Huang, J.1    Chen, K.2    Chen, J.3
  • 272
    • 33745221886 scopus 로고    scopus 로고
    • Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid
    • doi:10.1074/jbc.M601803200
    • Kishi Y, Okudaira S, Tanaka M et al (2006) Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid. J Biol Chem 281:17492-17500. doi:10.1074/jbc.M601803200
    • (2006) J Biol Chem , vol.281 , pp. 17492-17500
    • Kishi, Y.1    Okudaira, S.2    Tanaka, M.3
  • 273
    • 38049047118 scopus 로고    scopus 로고
    • Autotaxin: A secreted autocrine/paracrine factor that promotes glioma invasion
    • doi:10.1007/s11060-007-9480-6
    • Hoelzinger DB, Nakada M, Demuth T et al (2008) Autotaxin: a secreted autocrine/paracrine factor that promotes glioma invasion. J Neurooncol 86:297-309. doi:10.1007/s11060-007-9480-6
    • (2008) J Neurooncol , vol.86 , pp. 297-309
    • Hoelzinger, D.B.1    Nakada, M.2    Demuth, T.3
  • 274
    • 79959840536 scopus 로고    scopus 로고
    • Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells
    • doi:10.1007/s11060-010-0377-4
    • Yu F, Ng SS, Chow BK et al (2011) Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells. J Neurooncol 103:187-195. doi:10.1007/s11060-010-0377-4
    • (2011) J Neurooncol , vol.103 , pp. 187-195
    • Yu, F.1    Ng, S.S.2    Chow, B.K.3
  • 275
    • 79955575370 scopus 로고    scopus 로고
    • Intersectin1-s is involved in migration and invasion of human glioma cells
    • doi:10.1002/jnr.22616
    • Ma Y, Wang B, Li W et al (2011) Intersectin1-s is involved in migration and invasion of human glioma cells. J Neurosci Res 89:1079-1090. doi:10.1002/jnr.22616
    • (2011) J Neurosci Res , vol.89 , pp. 1079-1090
    • Ma, Y.1    Wang, B.2    Li, W.3
  • 276
    • 80155131275 scopus 로고    scopus 로고
    • Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype
    • doi:10.1158/0008-5472.CAN-11-0744
    • Soroceanu L, Matlaf L, Bezrookove V et al (2011) Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype. Cancer Res 71:6643-6653. doi:10.1158/0008-5472.CAN-11-0744
    • (2011) Cancer Res , vol.71 , pp. 6643-6653
    • Soroceanu, L.1    Matlaf, L.2    Bezrookove, V.3
  • 277
    • 84855419216 scopus 로고    scopus 로고
    • Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness
    • doi:10.1158/1078-0432.CCR-11-0880
    • Lemke D, Pfenning PN, Sahm F et al (2012) Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness. Clin Cancer Res 18:105-117. doi:10.1158/1078-0432.CCR-11-0880
    • (2012) Clin Cancer Res , vol.18 , pp. 105-117
    • Lemke, D.1    Pfenning, P.N.2    Sahm, F.3
  • 278
    • 84863049147 scopus 로고    scopus 로고
    • A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis
    • doi:10.1093/carcin/bgr289
    • Zhang J, Sarkar S, Cua R et al (2012) A dialog between glioma and microglia that promotes tumor invasiveness through the CCL2/CCR2/interleukin-6 axis. Carcinogenesis 33:312-319. doi:10.1093/carcin/bgr289
    • (2012) Carcinogenesis , vol.33 , pp. 312-319
    • Zhang, J.1    Sarkar, S.2    Cua, R.3
  • 279
    • 84873740471 scopus 로고    scopus 로고
    • The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
    • doi:10.1038/onc.2012.111
    • Galavotti S, Bartesaghi S, Faccenda D et al (2013) The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells. Oncogene 32:699-712. doi:10.1038/onc.2012.111
    • (2013) Oncogene , vol.32 , pp. 699-712
    • Galavotti, S.1    Bartesaghi, S.2    Faccenda, D.3
  • 280
    • 84872677092 scopus 로고    scopus 로고
    • ARK5 promotes glioma cell invasion, and its elevated expression is correlated with poor clinical outcome
    • doi:10.1016/j.ejca.2012.09.018
    • Lu S, Niu N, Guo H et al (2013) ARK5 promotes glioma cell invasion, and its elevated expression is correlated with poor clinical outcome. Eur J Cancer 49:752-763. doi:10.1016/j.ejca.2012.09.018
    • (2013) Eur J Cancer , vol.49 , pp. 752-763
    • Lu, S.1    Niu, N.2    Guo, H.3
  • 281
    • 84878548018 scopus 로고    scopus 로고
    • Intracellular NAD(H) levels control motility and invasion of glioma cells
    • doi:10.1007/s00018-012-1249-1
    • Van Horssen R, Willemse M, Haeger A et al (2013) Intracellular NAD(H) levels control motility and invasion of glioma cells. Cell Mol Life Sci. doi:10.1007/s00018-012-1249-1
    • (2013) Cell Mol Life Sci
    • Van Horssen, R.1    Willemse, M.2    Haeger, A.3
  • 282
    • 77957342015 scopus 로고    scopus 로고
    • Aquaporin-4 in glioma invasion and an analysis ofmolecularmechanisms
    • doi:10.1016/j.jocn.2010.02.014
    • Ding T, Gu F, Fu L, Ma YJ (2010) Aquaporin-4 in glioma invasion and an analysis ofmolecularmechanisms. J Clin Neurosci 17:1359-1361. doi:10.1016/j.jocn.2010.02.014
    • (2010) J Clin Neurosci , vol.17 , pp. 1359-1361
    • Ding, T.1    Gu, F.2    Fu, L.3    Ma, Y.J.4
  • 283
    • 78650230042 scopus 로고    scopus 로고
    • Invasion of human glioma cells is regulated by multiple chloride channels including ClC-3
    • Lui VC, Lung SS, Pu JK et al (2010) Invasion of human glioma cells is regulated by multiple chloride channels including ClC-3. Anticancer Res 30:4515-4524
    • (2010) Anticancer Res , vol.30 , pp. 4515-4524
    • Lui, V.C.1    Lung, S.S.2    Pu, J.K.3
  • 284
    • 84861569709 scopus 로고    scopus 로고
    • Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation
    • doi:10.1371/journal.pbio.1001320
    • Garzon-Muvdi T, Schiapparelli P, Aprhys C et al (2012) Regulation of brain tumor dispersal by NKCC1 through a novel role in focal adhesion regulation. PLoS Biol 10:e1001320. doi:10.1371/journal.pbio.1001320
    • (2012) PLoS Biol , vol.10
    • Garzon-Muvdi, T.1    Schiapparelli, P.2    Aprhys, C.3
  • 285
    • 80054920671 scopus 로고    scopus 로고
    • With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume
    • doi:10.1152/ajpcell.00203.2011
    • Haas BR, Cuddapah VA, Watkins S et al (2011) With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volume. Am J Physiol Cell Physiol 301:C1150-60. doi:10.1152/ajpcell.00203.2011
    • (2011) Am J Physiol Cell Physiol , vol.301
    • Haas, B.R.1    Cuddapah, V.A.2    Watkins, S.3
  • 286
    • 84883191664 scopus 로고    scopus 로고
    • STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion
    • doi:10.1007/s00424-013-1254-8
    • Motiani RK, Hyzinski-Garcia MC, Zhang X et al (2013) STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion. Pflugers Arch. doi:10.1007/s00424-013-1254-8
    • (2013) Pflugers Arch
    • Motiani, R.K.1    Hyzinski-Garcia, M.C.2    Zhang, X.3
  • 287
    • 84874667032 scopus 로고    scopus 로고
    • Knockdown of RLIP76 expression byRNAinterference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells
    • doi:10.1007/s11060-013-1045-2
    • Wang Q, Qian J, Wang J et al (2013) Knockdown of RLIP76 expression byRNAinterference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells. J Neurooncol 112:73-82. doi:10.1007/s11060-013-1045-2
    • (2013) J Neurooncol , vol.112 , pp. 73-82
    • Wang, Q.1    Qian, J.2    Wang, J.3
  • 288
    • 17844397949 scopus 로고    scopus 로고
    • The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
    • DOI 10.1215/S1152851704001061
    • Brat DJ, Bellail AC, Van Meir EG (2005) The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis.Neuro- Oncol 7:122-33. doi:10.1215/S1152851704001061 (Pubitemid 40590513)
    • (2005) Neuro-Oncology , vol.7 , Issue.2 , pp. 122-133
    • Brat, D.J.1    Bellail, A.C.2    Van Meir, E.G.3
  • 289
    • 79952184099 scopus 로고    scopus 로고
    • Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma
    • doi:10.1007/s11060-010-0290-x
    • Reynés G, Vila V, Martín M et al (2011) Circulating markers of angiogenesis, inflammation, and coagulation in patients with glioblastoma. J Neuro-Oncol 102:35-41. doi:10.1007/s11060-010-0290-x
    • (2011) J Neuro-Oncol , vol.102 , pp. 35-41
    • Reynés, G.1    Vila, V.2    Martín, M.3
  • 290
    • 78651275992 scopus 로고    scopus 로고
    • Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB
    • doi:10.1007/s11060-010-0220-y
    • Sun S, Wang Q, Giang A et al (2011) Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB. J Neuro-Oncol 101:1-14. doi:10.1007/s11060-010-0220-y
    • (2011) J Neuro-Oncol , vol.101 , pp. 1-14
    • Sun, S.1    Wang, Q.2    Giang, A.3
  • 292
    • 77951735629 scopus 로고    scopus 로고
    • IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1
    • Li R, Li G, Deng L et al (2010) IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1. Oncol Rep 23:1553-9
    • (2010) Oncol Rep , vol.23 , pp. 1553-1559
    • Li, R.1    Li, G.2    Deng, L.3
  • 293
    • 79952189567 scopus 로고    scopus 로고
    • IL-6 promotion of glioblastoma cell invasion and angiogenesis in U251 and T98G cell lines
    • doi:10.1007/s11060-010-0158-0
    • Liu Q, Li G, Li R et al (2010) IL-6 promotion of glioblastoma cell invasion and angiogenesis in U251 and T98G cell lines. J Neuro-Oncol 100:165-76. doi:10.1007/s11060-010-0158-0
    • (2010) J Neuro-Oncol , vol.100 , pp. 165-176
    • Liu, Q.1    Li, G.2    Li, R.3
  • 294
    • 70350223977 scopus 로고    scopus 로고
    • Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth
    • doi:10.1002/stem.188
    • Wang H, Lathia JD, Wu Q et al (2009) Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells 27:2393-404. doi:10.1002/stem.188
    • (2009) Stem Cells , vol.27 , pp. 2393-2404
    • Wang, H.1    Lathia, J.D.2    Wu, Q.3
  • 296
    • 28544453276 scopus 로고    scopus 로고
    • Prognostic and clinical implication of IL-6 expression in glioblastoma multiforme
    • doi:10.1016/j.jocn.2004.11.017
    • Chang C-Y, Li M-C, Liao S-L et al (2005) Prognostic and clinical implication of IL-6 expression in glioblastoma multiforme. J Clin Neurosci Off J Neurosurg Soc Australas 12:930-3. doi:10.1016/j.jocn.2004.11.017
    • (2005) J Clin Neurosci off J Neurosurg Soc Australas , vol.12 , pp. 930-933
    • Chang, C.-Y.1    Li, M.-C.2    Liao, S.-L.3
  • 298
    • 33751256842 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: Implications for angiogenesis and glioma cell invasion
    • DOI 10.1038/labinvest.3700482, PII 3700482
    • ZagzagD, Lukyanov Y, Lan L et al (2006) Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion. Laboratory investigation. J Tech Methods Pathol 86:1221-32. doi:10.1038/labinvest.3700482 (Pubitemid 44789912)
    • (2006) Laboratory Investigation , vol.86 , Issue.12 , pp. 1221-1232
    • Zagzag, D.1    Lukyanov, Y.2    Lan, L.3    Ali, M.A.4    Esencay, M.5    Mendez, O.6    Yee, H.7    Voura, E.B.8    Newcomb, E.W.9
  • 299
    • 33646598696 scopus 로고    scopus 로고
    • CXCR4 expression mediates glioma cell invasiveness
    • doi:10.1038/sj.onc.1209302
    • Ehtesham M, Winston JA, Kabos P, Thompson RC (2006) CXCR4 expression mediates glioma cell invasiveness. Oncogene 25:2801-6. doi:10.1038/sj.onc. 1209302
    • (2006) Oncogene , vol.25 , pp. 2801-2806
    • Ehtesham, M.1    Winston, J.A.2    Kabos, P.3    Thompson, R.C.4
  • 300
    • 48749124404 scopus 로고    scopus 로고
    • Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: One plausible explanation of Scherer's structures
    • doi:10.2353/ajpath.2008.071197
    • Zagzag D, Esencay M, Mendez O et al (2008) Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures. Am J Pathol 173:545-60. doi:10.2353/ajpath.2008.071197
    • (2008) Am J Pathol , vol.173 , pp. 545-560
    • Zagzag, D.1    Esencay, M.2    Mendez, O.3
  • 301
    • 58149314184 scopus 로고    scopus 로고
    • CXCR4 mediates the proliferation of glioblastoma progenitor cells
    • doi:10.1016/j.canlet.2008.09.034
    • Ehtesham M, Mapara KY, Stevenson CB, Thompson RC (2009) CXCR4 mediates the proliferation of glioblastoma progenitor cells. Cancer Lett 274:305-12. doi:10.1016/j.canlet.2008.09.034
    • (2009) Cancer Lett , vol.274 , pp. 305-312
    • Ehtesham, M.1    Mapara, K.Y.2    Stevenson, C.B.3    Thompson, R.C.4
  • 302
    • 42449103074 scopus 로고    scopus 로고
    • Nestin, PDGFRbeta, CXCL12 and VEGF in glioma patients: Different profiles of (pro-angiogenic) molecule expression are related with tumor grade and may provide prognostic information
    • Maderna E, Salmaggi A, Calatozzolo C et al (2007) Nestin, PDGFRbeta, CXCL12 and VEGF in glioma patients: different profiles of (pro-angiogenic) molecule expression are related with tumor grade and may provide prognostic information. Cancer Biol Ther 6:1018-1024 (Pubitemid 351574951)
    • (2007) Cancer Biology and Therapy , vol.6 , Issue.7 , pp. 1018-1024
    • Maderna, E.1    Salmaggi, A.2    Calatozzolo, C.3    Limido, L.4    Pollo, B.5
  • 303
    • 34247848682 scopus 로고    scopus 로고
    • Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival
    • doi:10.1227/01.NEU.0000290905.53685.A2
    • Bian XW, Yang SX, Chen JH et al (2007) Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival. Neurosurg 61:570-579. doi:10.1227/01.NEU.0000290905. 53685.A2
    • (2007) Neurosurg , vol.61 , pp. 570-579
    • Bian, X.W.1    Yang, S.X.2    Chen, J.H.3
  • 304
    • 0038179723 scopus 로고    scopus 로고
    • Cost of migration: Invasion of malignant gliomas and implications for treatment
    • DOI 10.1200/JCO.2003.05.063
    • Giese A, Bjerkvig R, Berens ME, Westphal M (2003) Cost of migration: invasion of malignant gliomas and implications for treatment. J Clin Oncol Off J Am Soc Clin Oncol 21:1624-36. doi:10.1200/JCO.2003.05.063 (Pubitemid 46594118)
    • (2003) Journal of Clinical Oncology , vol.21 , Issue.8 , pp. 1624-1636
    • Giese, A.1    Bjerkvig, R.2    Berens, M.E.3    Westphal, M.4
  • 305
    • 0029995767 scopus 로고    scopus 로고
    • Glioma invasion in the central nervous system
    • discussion 250-2
    • Giese A, Westphal M (1996) Glioma invasion in the central nervous system. Neurosurg 39:235-50, discussion 250-2
    • (1996) Neurosurg , vol.39 , pp. 235-250
    • Giese, A.1    Westphal, M.2
  • 306
    • 0034612289 scopus 로고    scopus 로고
    • Glioblastoma multiforme: The terminator
    • Holland EC (2000) Glioblastoma multiforme: the terminator. Proc Natl Acad Sci U S A 97:6242-4
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 6242-6244
    • Holland, E.C.1
  • 307
    • 77955085751 scopus 로고    scopus 로고
    • Chemokines and glioma: Invasion and more
    • doi:10.1016/j.jneuroim.2010.05.019
    • Sciumè G, Santoni A, Bernardini G (2010) Chemokines and glioma: invasion and more. J Neuroimmunol 224:8-12. doi:10.1016/j.jneuroim.2010.05.019
    • (2010) J Neuroimmunol , vol.224 , pp. 8-12
    • Sciumè, G.1    Santoni, A.2    Bernardini, G.3
  • 308
    • 73949114574 scopus 로고    scopus 로고
    • Sensing invasion: Cell surface receptors driving spreading of glioblastoma
    • doi:10.1002/jcp.21901
    • Teodorczyk M, Martin-Villalba A (2010) Sensing invasion: cell surface receptors driving spreading of glioblastoma. J Cell Physiol 222:1-10. doi:10.1002/jcp.21901
    • (2010) J Cell Physiol , vol.222 , pp. 1-10
    • Teodorczyk, M.1    Martin-Villalba, A.2
  • 309
    • 33847336870 scopus 로고    scopus 로고
    • Molecular targets of glioma invasion
    • doi:10.1007/s00018-007-6342-5
    • Nakada M, Nakada S, Demuth T et al (2007) Molecular targets of glioma invasion. CellMol Life Sci:CMLS 64:458-78. doi:10.1007/s00018-007-6342-5
    • (2007) CellMol Life Sci:CMLS , vol.64 , pp. 458-478
    • Nakada, M.1    Nakada, S.2    Demuth, T.3
  • 310
    • 0029034425 scopus 로고
    • The in vitro motility of human gliomas increases with increasing grade of malignancy
    • Chicoine MR, Silbergeld DL (1995) The in vitro motility of human gliomas increases with increasing grade of malignancy. Cancer 75:2904-9
    • (1995) Cancer , vol.75 , pp. 2904-2909
    • Chicoine, M.R.1    Silbergeld, D.L.2
  • 311
    • 0028024338 scopus 로고
    • Use of the Matrigel-based assay to measure the iuvasiveness of leukemic cells
    • Janiak M, Hashmi HR, Janowska-Wieczorek A (1994) Use of the Matrigel-based assay to measure the invasiveness of leukemic cells. Exp Hematol 22:559-65 (Pubitemid 24300489)
    • (1994) Experimental Hematology , vol.22 , Issue.7 , pp. 559-565
    • Janiak, M.1    Hashmi, H.R.2    Janowska-Wieczorek, A.3
  • 312
    • 0034859138 scopus 로고    scopus 로고
    • Tracking the invasiveness of human astrocytoma cells by using green fluorescent protein in an organotypical brain slice model
    • Jung S, Ackerley C, Ivanchuk S et al (2001) Tracking the invasiveness of human astrocytoma cells by using green fluorescent protein in an organotypical brain slice model. J Neurosurg 94:80-9. doi:10.3171/jns.2001.94.1.0080 (Pubitemid 32799476)
    • (2001) Journal of Neurosurgery , vol.94 , Issue.1 , pp. 80-89
    • Jung, S.1    Ackerley, C.2    Ivanchuk, S.3    Mondal, S.4    Becker, L.E.5    Rutka, J.T.6
  • 313
    • 67649120009 scopus 로고    scopus 로고
    • Biology of angiogenesis and invasion in glioma
    • doi:10.1016/j.nurt.2009.04.001
    • TateMC, AghiMK (2009) Biology of angiogenesis and invasion in glioma. Neurotherapeutics J Am Soc Exp NeuroTherapeutics 6:447-57. doi:10.1016/j.nurt. 2009.04.001
    • (2009) Neurotherapeutics J Am Soc Exp NeuroTherapeutics , vol.6 , pp. 447-457
    • Tate, M.C.1    Aghi, M.K.2
  • 314
    • 68049093213 scopus 로고    scopus 로고
    • Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy
    • doi:10.1158/1078-0432.CCR-09-0575
    • Lucio-Eterovic AK, Piao Y, De Groot JF (2009) Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin Cancer Res Off J Am Assoc Cancer Res 15:4589-99. doi:10.1158/1078-0432.CCR- 09-0575
    • (2009) Clin Cancer Res off J Am Assoc Cancer Res , vol.15 , pp. 4589-4599
    • Lucio-Eterovic, A.K.1    Piao, Y.2    De Groot, J.F.3
  • 316
    • 34248363956 scopus 로고    scopus 로고
    • Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer
    • doi:10.1073/pnas. 0609139104
    • Mehrian-Shai R, Chen CD, Shi T et al (2007) Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer. Proc Natl Acad Sci U S A 104:5563 - 8. doi:10.1073/pnas. 0609139104
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 5563-5568
    • Mehrian-Shai, R.1    Chen, C.D.2    Shi, T.3
  • 317
    • 79953024876 scopus 로고    scopus 로고
    • The different HMGA1 expression of total population of glioblastoma cell line U251 and glioma stemcells isolated fromU251
    • doi:10.1016/j.brainres.2011.01.105
    • Fan H, Guo H, Zhang IY et al (2011) The different HMGA1 expression of total population of glioblastoma cell line U251 and glioma stemcells isolated fromU251. Brain Res 1384:9-14. doi:10.1016/j.brainres.2011.01.105
    • (2011) Brain Res , vol.1384 , pp. 9-14
    • Fan, H.1    Guo, H.2    Zhang, I.Y.3
  • 318
    • 84862909038 scopus 로고    scopus 로고
    • Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma
    • doi:10.1084/jem.20111102
    • LiM, Mukasa A, IndaMMet al (2011) Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma. J Exp Med 208:2657-2673. doi:10.1084/jem.20111102
    • (2011) J Exp Med , vol.208 , pp. 2657-2673
    • Li, M.1    Mukasa, A.2    Inda, M.M.3
  • 319
    • 9144232309 scopus 로고    scopus 로고
    • Molecular mechanisms of glioma cell migration and invasion
    • DOI 10.1007/s11060-004-2751-6
    • Demuth T, Berens ME(2004) Molecularmechanisms of glioma cell migration and invasion. J Neurooncol 70:217-228. doi:10.1007/s11060-004-2751-6 (Pubitemid 39545733)
    • (2004) Journal of Neuro-Oncology , vol.70 , Issue.2 , pp. 217-228
    • Demuth, T.1    Berens, M.E.2
  • 320
    • 84885190125 scopus 로고    scopus 로고
    • Understanding glioma invasion: A necessity for effective therapy
    • doi:10.1016/j.wneu.2011.10.003
    • Peruzzi P, Chiocca EA (2011) Understanding glioma invasion: a necessity for effective therapy. World Neurosurgery. doi:10.1016/j.wneu.2011.10.003
    • (2011) World Neurosurgery
    • Peruzzi, P.1    Chiocca, E.A.2


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