AMOG/β2 and glioma invasion: Does loss of AMOG make tumour cells run amok?

Neuropathology and Applied Neurobiology

Volumn 29, Issue 4, 2003, Pages 370-377

  Senner, Volker ^a   Schmidtpeter, S ^a   Braune, S ^a   Puttmann S ^a   Thanos, S ^a   Bartsch, U ^b   Schachner, M ^b   Paulus, W ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b Zentrum fur Molec Neurobiologie   (Germany)

Author keywords

Adhesion; AMOG (adhesion molecule on glia); Glioma; Invasion; Na, K ATPase

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CELL ADHESION MOLECULE; ADENOSINE TRIPHOSPHATASE; ATP1B2 PROTEIN, HUMAN; ATP1B2 PROTEIN, RAT; CATION TRANSPORT PROTEIN; NERVE CELL ADHESION MOLECULE; RECOMBINANT PROTEIN;

ANIMAL CELL; ARTICLE; BETA CHAIN; BRAIN BIOPSY; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; GENETIC TRANSFECTION; GLIA CELL; GLIOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TUMOR CELL LINE; ANIMAL; ASTROCYTOMA; BRAIN TUMOR; CELL CULTURE; CELL MOTION; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ASTROCYTOMA; BRAIN NEOPLASMS; CATION TRANSPORT PROTEINS; CELL ADHESION; CELL ADHESION MOLECULES, NEURONAL; CELL MOVEMENT; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; RATS; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED;

EID: 0042090216     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2990.2003.00473.x     Document Type: Article

References (28)

1. Antonicek H, Persohn E, Schachner M. Biochemical and functional characterization of a novel neuron-glia adhesion molecule that is involved in neuronal migration. J Cell Biol 1987; 104: 1587-95
2. Antonicek H, Schachner M. The adhesion molecule on glia (AMOG) incorporated into lipid vesicles binds to subpopulations of neurons. J Neurosci 1988; 8: 2961-6
3. Belusa R, Wang ZM, Matsubara T, Sahlgren B, Dulubova I, Nairn AC, Ruoslahti E, Greengard P, Aperia A. Mutation of the protein kinase C phosphorylation site on rat alpha1 Na+,K+-ATPase alters regulation of intracellular Na+ and pH and influences cell shape and adhesiveness. J Biol Chem 1997; 272: 20179-84
4. Crambert G, Hasler U, Beggah AT, Yu C, Modyanov NN, Horisberger JD, Lelièvre L, Geering K. Transport and pharmacological properties of nine different human Na,K-ATPase isozymes. J Biol Chem 2000; 275: 1976-86
5. Embree LJ, Hess HH, Shein HM. Sodium-potassium adenosine triphosphatase activity in N-nitrosomethylurea-induced astrocytoma cells. Exp Neurol 1971; 31: 383-90
6. Florkiewicz RZ, Anchin J, Baird A. The inhibition of fibroblast growth factor-2 export by cardenolides implies a novel function for the catalytic subunit of Na+,K+-ATPase. J Biol Chem 1998; 273: 544-51
7. Gloor S, Antonicek H, Sweadner KJ, Pagliusi S, Frank R, Moos M, Schachner M. The adhesion molecule on glia (AMOG) is a homologue of the beta subunit of the Na,K-ATPase. J Cell Biol 1990; 110: 165-74
8. Hofer D, Drenckhahn D. Localisation of actin, villin, fimbrin, ezrin and ankyrin in rat taste receptor cells. Histochem Cell Biol 1999; 112: 79-86
9. Holland EC, Varmus HE. Basic fibroblast growth factor induces cell migration and proliferation after glia-specific gene transfer in mice. Proc Natl Acad Sci USA 1998; 95: 1218-23
10. Izumoto S, Ohnishi T, Arita N, Hiraga S, Taki T, Hayakawa T. Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion. Cancer Res 1996; 56: 1440-4
11. Kleihues P, Cavenee WK, eds. World Health Organization Classification of Tumours, Pathology and Genetics. Tumours of the Nervous System. Lyon: IARC Press, 2000
12. Koob R, Kraemer D, Trippe G, Aebi U, Drenckhahn D. Association of kidney and parotid Na+,K(+)-ATPase microsomes with actin and analogs of spectrin and ankyrin. Eur J Cell Biol 1990; 53: 93-100
13. Lecuona E, Luquin S, Avila J, Garcia-Segura LM, Martín-Vasallo P. Expression of the beta 1 and beta 2 (AMOG) subunits of the Na,K-ATPase in neural tissues: cellular and developmental distribution patterns. Brain Res Bull 1996; 40: 167-74
14. Maidment SL. The cytoskeleton and brain tumour cell migration. Anticancer Res 1997; 17: 4145-9
15. Martín-Vasallo P, Wetzel RK, Garcia-Segura LM, Molina-Holgado E, Arystarkhova E, Sweadner KJ. Oligodendrocytes in brain and optic nerve express the beta3 subunit isoform of Na,K-ATPase. Glia 2000; 31: 206-18
16. Merzak A, Koocheckpour S, Pilkington GJ. CD44 mediates human glioma cell adhesion and invasion in vitro. Cancer Res 1994; 54: 3988-92
17. Mobasheri A, Avila J, Cozar-Castellano I, Brownleader MD, Trevan M, Francis MJ, Lamb JF, Martín-Vasallo P. Na+,K+-ATPase isozyme diversity; comparative biochemistry and physiological implications of novel functional interactions. Biosci Rep 2000; 20: 51-91
18. Müller-Husmann G, Gloor S, Schachner M. Functional characterization of β isoforms of murine Na,K-ATPase. The adhesion molecule on glia (AMOG/β2), but not β1, promotes neurite outgrowth. J Biol Chem 1993; 268: 26260-7
19. Owens GC, Orr EA, Kleinschmidt DeMasters BK, Muschel RJ, Berens ME, Kruse CA. Overexpression of a transmembrane isoform of neural cell adhesion molecule alters invasiveness of rat CNS-1 glioma. Cancer Res 1998; 58: 2020-8
20. Pagliusi S, Antonicek H, Gloor S, Frank R, Moos M, Schachner M. Identification of a cDNA clone specific for the neural cell adhesion molecule AMOG. J Neurosci Res 1989; 22: 113-19
21. Paulus W, Baur I, Beutler AS, Reeves SA. Diffuse brain invasion of glioma cells requires β1 integrins. Lab Invest 1996; 75: 819-26
22. Paulus W. Brain extracellular matrix, adhesion molecules, and glioma invasion. In Brain Tumor Invasion. Eds T Mikkelsen, R Bjerkvig, OD Laerum, ML Rosenblum. New York: Wiley-Liss, 1998; 301-22
23. Peng L, Arystarkhova E, Sweadner KJ. Plasticity of Na,K-ATPase isoform expression in cultures of flat astrocytes: species differences in gene expression. Glia 1998; 24: 257-71
24. Pilkington GJ. Tumour cell migration in the central nervous system. Brain Pathol 1994; 4: 157-66
25. Senner V, Kismann E, Püttmann S, Hoess N, Baur I, Paulus W. L1 expressed by glioma cells promotes adhesion but not migration. Glia 2002; 38: 146-54
26. Senner V, Sturm A, Baur I, Schrell UH, Distel L, Paulus W. CD24 promotes invasion of glioma cells in vivo. J Neuropathol Exp Neurol 1999; 58: 795-802
27. Tonn JC, Bernstein JJ, Goldbrunner RH, eds. Processes of glioma invasion. Int J Dev Neurosci 1999; 17: 411-672
28. Watts AG, Sanchez-Watts G, Emanuel JR, Levenson R. Cell-specific expression of mRNAs encoding Na+,K(+)-ATPase alpha- and beta-subunit isoforms within the rat central nervous system. Proc Natl Acad Sci USA 1991; 88: 7425-9