Cacospongionolide and scalaradial, two marine sesterterpenoids as potent apoptosis-inducing factors in human carcinoma cell lines

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  De Stefano, Daniela ^a   Tommonaro, Giuseppina ^b   Malik, Shoaib Ahmad ^c   Iodice, Carmine ^b   de Rosa, Salvatore ^b   Maiuri, Maria Chiara ^a,c   Carnuccio, Rosa ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b CNR   (Italy)

^c INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CACOSPONGIONOLIDE; DAUNORUBICIN; DNA; SCALARADIAL; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; APOPTOSIS REGULATORY PROTEIN; CACOSPONGIONOLIDE B; DRUG DERIVATIVE; GAMMA BUTYROLACTONE; HOMOSTEROID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PYRAN DERIVATIVE; SESTERTERPENE; TRANSCRIPTION FACTOR RELA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CACOSPONGIA SCALARIS; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA CELL; CELL VIABILITY; COLON CARCINOMA; COMET ASSAY; CONCENTRATION RESPONSE; DNA FRAGMENTATION; DRUG EFFECT; DRUG POTENTIATION; FASCIOSPONGIA CAVERNOSA; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPONGE (PORIFERA); SQUAMOUS CELL CARCINOMA; UTERINE CERVIX CARCINOMA; ACTIVE TRANSPORT; ANIMAL; AQUATIC SPECIES; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; METABOLISM; TUMOR CELL LINE;

CACOSPONGIA SCALARIS; FASCIOSPONGIA CAVERNOSA;

4-BUTYROLACTONE; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AQUATIC ORGANISMS; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CELL SURVIVAL; DNA FRAGMENTATION; HOMOSTEROIDS; HUMANS; NF-KAPPA B P50 SUBUNIT; PORIFERA; PYRANS; SESTERTERPENES; TRANSCRIPTION FACTOR RELA;

EID: 84859235771     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033031     Document Type: Article

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