-
2
-
-
84856284021
-
Defective retinal vascular endothelial cell development as a consequence of impaired integrin alphavbeta8-mediated activation of transforming growth factor-beta
-
Arnold TD, Ferrero GM, Qiu H, Phan IT, Akhurst RJ, Huang EJ, Reichardt LF (2012). Defective retinal vascular endothelial cell development as a consequence of impaired integrin alphavbeta8-mediated activation of transforming growth factor-beta. J Neurosci 32, 1197-1206.
-
(2012)
J Neurosci
, vol.32
, pp. 1197-1206
-
-
Arnold, T.D.1
Ferrero, G.M.2
Qiu, H.3
Phan, I.T.4
Akhurst, R.J.5
Huang, E.J.6
Reichardt, L.F.7
-
3
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Batchelor TT et al. (2007). AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11, 83-95.
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
-
4
-
-
77951974893
-
Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1
-
Boulter E, Garcia-Mata R, Guilluy C, Dubash A, Rossi G, Brennwald PJ, Burridge K (2010). Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1. Nat Cell Biol 12, 477-483.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 477-483
-
-
Boulter, E.1
Garcia-Mata, R.2
Guilluy, C.3
Dubash, A.4
Rossi, G.5
Brennwald, P.J.6
Burridge, K.7
-
5
-
-
20144368274
-
High-resolution genome-wide mapping of genetic alterations in human glial brain tumors
-
Bredel M, Bredel C, Juric D, Harsh GR, Vogel H, Recht LD, Sikic BI (2005). High-resolution genome-wide mapping of genetic alterations in human glial brain tumors. Cancer Res 65, 4088-4096.
-
(2005)
Cancer Res
, vol.65
, pp. 4088-4096
-
-
Bredel, M.1
Bredel, C.2
Juric, D.3
Harsh, G.R.4
Vogel, H.5
Recht, L.D.6
Sikic, B.I.7
-
6
-
-
33846029123
-
A perivascular niche for brain tumor stem cells
-
Calabrese C et al. (2007). A perivascular niche for brain tumor stem cells. Cancer Cell 11, 69-82.
-
(2007)
Cancer Cell
, vol.11
, pp. 69-82
-
-
Calabrese, C.1
-
7
-
-
0036122427
-
Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI
-
Del Pozo MA, Kiosses WB, Alderson NB, Meller N, Hahn KM, Schwartz MA (2002). Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI. Nat Cell Biol 4, 232-239.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 232-239
-
-
Del Pozo, M.A.1
Kiosses, W.B.2
Alderson, N.B.3
Meller, N.4
Hahn, K.M.5
Schwartz, M.A.6
-
8
-
-
72949119124
-
Integrins in cancer: Biological implications and therapeutic opportunities
-
Desgrosellier JS, Cheresh DA (2010). Integrins in cancer: Biological implications and therapeutic opportunities. Nat Rev Cancer 10, 9-22.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 9-22
-
-
Desgrosellier, J.S.1
Cheresh, D.A.2
-
9
-
-
67650478384
-
Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway
-
Elfenbein A, Rhodes JM, Meller J, Schwartz MA, Matsuda M, Simons M (2009). Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. J Cell Biol 186, 75-83.
-
(2009)
J Cell Biol
, vol.186
, pp. 75-83
-
-
Elfenbein, A.1
Rhodes, J.M.2
Meller, J.3
Schwartz, M.A.4
Matsuda, M.5
Simons, M.6
-
10
-
-
62649101158
-
Cancer: The nuances of therapy
-
Ellis LM, Reardon DA (2009). Cancer: The nuances of therapy. Nature 458, 290-292.
-
(2009)
Nature
, vol.458
, pp. 290-292
-
-
Ellis, L.M.1
Reardon, D.A.2
-
11
-
-
33646533333
-
Transplanted glioma cells migrate and proliferate on host brain vasculature: A dynamic analysis
-
Farin A, Suzuki SO, Weiker M, Goldman JE, Bruce JN, Canoll P (2006). Transplanted glioma cells migrate and proliferate on host brain vasculature: A dynamic analysis. Glia 53, 799-808.
-
(2006)
Glia
, vol.53
, pp. 799-808
-
-
Farin, A.1
Suzuki, S.O.2
Weiker, M.3
Goldman, J.E.4
Bruce, J.N.5
Canoll, P.6
-
12
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS et al. (2009). Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 27, 4733-4740.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4733-4740
-
-
Friedman, H.S.1
-
14
-
-
77954730533
-
Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib
-
Gerstner ER, Chen PJ, Wen PY, Jain RK, Batchelor TT, Sorensen G (2010). Infiltrative patterns of glioblastoma spread detected via diffusion MRI after treatment with cediranib. Neuro Oncol 12, 466-472.
-
(2010)
Neuro Oncol
, vol.12
, pp. 466-472
-
-
Gerstner, E.R.1
Chen, P.J.2
Wen, P.Y.3
Jain, R.K.4
Batchelor, T.T.5
Sorensen, G.6
-
15
-
-
34648821254
-
Making a tumour's bed: Glioblastoma stem cells and the vascular niche
-
Gilbertson RJ, Rich JN (2007). Making a tumour's bed: Glioblastoma stem cells and the vascular niche. Nat Rev Cancer 7, 733-736.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 733-736
-
-
Gilbertson, R.J.1
Rich, J.N.2
-
16
-
-
80755152972
-
The astrocyte-expressed integrin alphavbeta8 governs blood vessel sprouting in the developing retina
-
Hirota S, Liu Q, Lee HS, Hossain MG, Lacy-Hulbert A, McCarty JH (2011). The astrocyte-expressed integrin alphavbeta8 governs blood vessel sprouting in the developing retina. Development 138, 5157-5166.
-
(2011)
Development
, vol.138
, pp. 5157-5166
-
-
Hirota, S.1
Liu, Q.2
Lee, H.S.3
Hossain, M.G.4
Lacy-Hulbert, A.5
McCarty, J.H.6
-
17
-
-
80055015155
-
Twisted tango: Brain tumor neurovascular interactions
-
Hjelmeland AB, Lathia JD, Sathornsumetee S, Rich JN (2011). Twisted tango: Brain tumor neurovascular interactions. Nat Neurosci 14, 1375-1381.
-
(2011)
Nat Neurosci
, vol.14
, pp. 1375-1381
-
-
Hjelmeland, A.B.1
Lathia, J.D.2
Sathornsumetee, S.3
Rich, J.N.4
-
18
-
-
36048994736
-
Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment
-
Hoelzinger DB, Demuth T, Berens ME (2007). Autocrine factors that sustain glioma invasion and paracrine biology in the brain microenvironment. J Natl Cancer Inst 99, 1583-1593.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1583-1593
-
-
Hoelzinger, D.B.1
Demuth, T.2
Berens, M.E.3
-
19
-
-
3342938063
-
Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis
-
Hoppe AD, Swanson JA (2004). Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis. Mol Biol Cell 15, 3509-3519.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 3509-3519
-
-
Hoppe, A.D.1
Swanson, J.A.2
-
20
-
-
0041806539
-
Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2
-
Hu B et al. (2003). Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2. Proc Natl Acad Sci USA 100, 8904-8909.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8904-8909
-
-
Hu, B.1
-
21
-
-
70849099495
-
The extracellular matrix: Not just pretty fibrils
-
Hynes RO (2009). The extracellular matrix: Not just pretty fibrils. Science 326, 1216-1219.
-
(2009)
Science
, vol.326
, pp. 1216-1219
-
-
Hynes, R.O.1
-
22
-
-
78650364449
-
Beta8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart
-
Jung Y, Kissil JL, McCarty JH (2011). beta8 integrin and band 4.1B cooperatively regulate morphogenesis of the embryonic heart. Dev Dyn 240, 271-277.
-
(2011)
Dev Dyn
, vol.240
, pp. 271-277
-
-
Jung, Y.1
Kissil, J.L.2
McCarty, J.H.3
-
23
-
-
2642533612
-
Integrin beta3 overexpression suppresses tumor growth in a human model of gliomagenesis: Implications for the role of beta3 overexpression in glioblastoma multiforme
-
Kanamori M, Vanden Berg SR, Bergers G, Berger MS, Pieper RO (2004). Integrin beta3 overexpression suppresses tumor growth in a human model of gliomagenesis: Implications for the role of beta3 overexpression in glioblastoma multiforme. Cancer Res 64, 2751-2758.
-
(2004)
Cancer Res
, vol.64
, pp. 2751-2758
-
-
Kanamori, M.1
Vanden Berg, S.R.2
Bergers, G.3
Berger, M.S.4
Pieper, R.O.5
-
24
-
-
79952740612
-
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
-
Keunen O et al. (2011). Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci USA 108, 3749-3754.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 3749-3754
-
-
Keunen, O.1
-
26
-
-
33645395980
-
In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes
-
Kissler S, Stern P, Takahashi K, Hunter K, Peterson LB, Wicker LS (2006). In vivo RNA interference demonstrates a role for Nramp1 in modifying susceptibility to type 1 diabetes. Nat Genet 38, 479-483.
-
(2006)
Nat Genet
, vol.38
, pp. 479-483
-
-
Kissler, S.1
Stern, P.2
Takahashi, K.3
Hunter, K.4
Peterson, L.B.5
Wicker, L.S.6
-
27
-
-
33745833014
-
Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation
-
Lakhe-Reddy S et al. (2006). Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation. J Biol Chem 281, 19688-19699.
-
(2006)
J Biol Chem
, vol.281
, pp. 19688-19699
-
-
Lakhe-Reddy, S.1
-
28
-
-
51049123414
-
A six-gene signature predicting breast cancer lung metastasis
-
Landemaine T et al. (2008). A six-gene signature predicting breast cancer lung metastasis. Canc Res 68, 6092-6099.
-
(2008)
Canc Res
, vol.68
, pp. 6092-6099
-
-
Landemaine, T.1
-
29
-
-
77956245743
-
Integrin alpha 6 regulates glioblastoma stem cells
-
Lathia JD et al. (2010). Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell 6, 421-432.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 421-432
-
-
Lathia, J.D.1
-
30
-
-
77957787559
-
Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase
-
Li X, Lee AY (2010). Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase. J Biol Chem 285, 32436-32445.
-
(2010)
J Biol Chem
, vol.285
, pp. 32436-32445
-
-
Li, X.1
Lee, A.Y.2
-
31
-
-
84862778946
-
BetaPix plays a dual role in cerebral vascular stability and angiogenesis, and interacts with integrin alphavbeta8
-
Liu J, Zeng L, Kennedy RM, Gruenig NM, Childs SJ (2012). betaPix plays a dual role in cerebral vascular stability and angiogenesis, and interacts with integrin alphavbeta8. Dev Biol 363, 95-105.
-
(2012)
Dev Biol
, vol.363
, pp. 95-105
-
-
Liu, J.1
Zeng, L.2
Kennedy, R.M.3
Gruenig, N.M.4
Childs, S.J.5
-
32
-
-
68049093213
-
Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy
-
Lucio-Eterovic AK, Piao Y, de Groot JF (2009). Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin Cancer Res 15, 4589-4599.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4589-4599
-
-
Lucio-Eterovic, A.K.1
Piao, Y.2
De Groot, J.F.3
-
34
-
-
67749099606
-
Cell adhesion and signaling networks in brain neurovascular units
-
McCarty JH (2009). Cell adhesion and signaling networks in brain neurovascular units. Curr Opin Hematol 16, 209-214.
-
(2009)
Curr Opin Hematol
, vol.16
, pp. 209-214
-
-
McCarty, J.H.1
-
35
-
-
26444484570
-
An interaction between αvβ8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain
-
McCarty JH, Cook AA, Hynes RO (2005a). An interaction between αvβ8 integrin and Band 4.1B via a highly conserved region of the Band 4.1 C-terminal domain. Proc Natl Acad Sci USA 102, 13479-13483.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13479-13483
-
-
McCarty, J.H.1
Cook, A.A.2
Hynes, R.O.3
-
36
-
-
13444249941
-
Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death
-
McCarty JH, Lacy-Hulbert A, Charest A, Bronson RT, Crowley D, Housman D, Savill J, Roes J, Hynes RO (2005b). Selective ablation of alphav integrins in the central nervous system leads to cerebral hemorrhage, seizures, axonal degeneration and premature death. Development 132, 165-176.
-
(2005)
Development
, vol.132
, pp. 165-176
-
-
McCarty, J.H.1
Lacy-Hulbert, A.2
Charest, A.3
Bronson, R.T.4
Crowley, D.5
Housman, D.6
Savill, J.7
Roes, J.8
Hynes, R.O.9
-
37
-
-
0036837873
-
Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins
-
McCarty JH et al. (2002). Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins. Mol Cell Biol 22, 7667-7677.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7667-7677
-
-
McCarty, J.H.1
-
38
-
-
0036682158
-
The integrin family of cell adhesion molecules has multiple functions within the CNS
-
Milner R, Campbell IL (2002). The integrin family of cell adhesion molecules has multiple functions within the CNS. J Neurosci Res 69, 286-291.
-
(2002)
J Neurosci Res
, vol.69
, pp. 286-291
-
-
Milner, R.1
Campbell, I.L.2
-
39
-
-
80052795031
-
Beta8 integrin is essential for neuroblast migration in the rostral migratory stream
-
Mobley AK, McCarty JH (2011). beta8 integrin is essential for neuroblast migration in the rostral migratory stream. Glia 59, 1579-1587.
-
(2011)
Glia
, vol.59
, pp. 1579-1587
-
-
Mobley, A.K.1
McCarty, J.H.2
-
40
-
-
69449106828
-
β8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain
-
Mobley AK, Tchaicha JH, Shin J, Hossain MG, McCarty JH (2009). β8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain. J Cell Sci 122, 1842-1851.
-
(2009)
J Cell Sci
, vol.122
, pp. 1842-1851
-
-
Mobley, A.K.1
Tchaicha, J.H.2
Shin, J.3
Hossain, M.G.4
McCarty, J.H.5
-
41
-
-
66149117890
-
Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases
-
Moissoglu K, McRoberts KS, Meier JA, Theodorescu D, Schwartz MA (2009). Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases. Cancer Res 69, 2838-2844.
-
(2009)
Cancer Res
, vol.69
, pp. 2838-2844
-
-
Moissoglu, K.1
McRoberts, K.S.2
Meier, J.A.3
Theodorescu, D.4
Schwartz, M.A.5
-
42
-
-
0037192933
-
The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1
-
Mu D, Cambier S, Fjellbirkeland L, Baron JL, Munger JS, Kawakatsu H, Sheppard D, Broaddus VC, Nishimura SL (2002). The integrin alpha(v)beta8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-beta1. J Cell Biol 157, 493-507.
-
(2002)
J Cell Biol
, vol.157
, pp. 493-507
-
-
Mu, D.1
Cambier, S.2
Fjellbirkeland, L.3
Baron, J.L.4
Munger, J.S.5
Kawakatsu, H.6
Sheppard, D.7
Broaddus, V.C.8
Nishimura, S.L.9
-
43
-
-
33847336870
-
Molecular targets of glioma invasion
-
Nakada M, Nakada S, Demuth T, Tran NL, Hoelzinger DB, Berens ME (2007). Molecular targets of glioma invasion. Cell Mol Life Sci 64, 458-478.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 458-478
-
-
Nakada, M.1
Nakada, S.2
Demuth, T.3
Tran, N.L.4
Hoelzinger, D.B.5
Berens, M.E.6
-
44
-
-
80155177915
-
TGF-beta signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development
-
Nguyen HL, Lee YJ, Shin J, Lee E, Park SO, McCarty JH, Oh SP (2011). TGF-beta signaling in endothelial cells, but not neuroepithelial cells, is essential for cerebral vascular development. Lab Invest 91, 1554-1563.
-
(2011)
Lab Invest
, vol.91
, pp. 1554-1563
-
-
Nguyen, H.L.1
Lee, Y.J.2
Shin, J.3
Lee, E.4
Park, S.O.5
McCarty, J.H.6
Oh, S.P.7
-
45
-
-
70449517400
-
Antiangiogenic therapies for high-grade glioma
-
Norden AD, Drappatz J, Wen PY (2009). Antiangiogenic therapies for high-grade glioma. Nat Rev Neurol 5, 610-620.
-
(2009)
Nat Rev Neurol
, vol.5
, pp. 610-620
-
-
Norden, A.D.1
Drappatz, J.2
Wen, P.Y.3
-
46
-
-
78751681684
-
Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme
-
Ovaska K et al. (2010). Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme. Genome Med 2, 65.
-
(2010)
Genome Med
, vol.2
, pp. 65
-
-
Ovaska, K.1
-
47
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M, Allen E, Hudock J, Takeda T, Okuyama H, Vinals F, Inoue M, Bergers G, Hanahan D, Casanovas O (2009). Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 15, 220-231.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
Takeda, T.4
Okuyama, H.5
Vinals, F.6
Inoue, M.7
Bergers, G.8
Hanahan, D.9
Casanovas, O.10
-
48
-
-
27344444684
-
Vascular development of the brain requires beta8 integrin expression in the neuroepithelium
-
Proctor JM, Zang K, Wang D, Wang R, Reichardt LF (2005). Vascular development of the brain requires beta8 integrin expression in the neuroepithelium. J Neurosci 25, 9940-9948.
-
(2005)
J Neurosci
, vol.25
, pp. 9940-9948
-
-
Proctor, J.M.1
Zang, K.2
Wang, D.3
Wang, R.4
Reichardt, L.F.5
-
49
-
-
79953840934
-
A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma
-
Reardon DA et al. (2011). A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma. J Natl Compr Canc Netw 9, 414-427.
-
(2011)
J Natl Compr Canc Netw
, vol.9
, pp. 414-427
-
-
Reardon, D.A.1
-
50
-
-
27544459331
-
In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation
-
Riemenschneider MJ, Mueller W, Betensky RA, Mohapatra G, Louis DN (2005). In situ analysis of integrin and growth factor receptor signaling pathways in human glioblastomas suggests overlapping relationships with focal adhesion kinase activation. Am J Pathol 167, 1379-1387.
-
(2005)
Am J Pathol
, vol.167
, pp. 1379-1387
-
-
Riemenschneider, M.J.1
Mueller, W.2
Betensky, R.A.3
Mohapatra, G.4
Louis, D.N.5
-
51
-
-
0035917522
-
EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin
-
Shamah SM, Lin MZ, Goldberg JL, Estrach S, Sahin M, Hu L, Neve RL, Corfas G, Debant A, Greenberg ME (2001). EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin. Cell 105, 233-244.
-
(2001)
Cell
, vol.105
, pp. 233-244
-
-
Shamah, S.M.1
Lin, M.Z.2
Goldberg, J.L.3
Estrach, S.4
Sahin, M.5
Hu, L.6
Neve, R.L.7
Corfas, G.8
Debant, A.9
Greenberg, M.E.10
-
52
-
-
34250163937
-
A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth
-
Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D, Ohmori O, Bigner DD, Friedman HS, Rich JN (2007). A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. Mol Carcinog 46, 488-496.
-
(2007)
Mol Carcinog
, vol.46
, pp. 488-496
-
-
Shi, Q.1
Hjelmeland, A.B.2
Keir, S.T.3
Song, L.4
Wickman, S.5
Jackson, D.6
Ohmori, O.7
Bigner, D.D.8
Friedman, H.S.9
Rich, J.N.10
-
53
-
-
0035392982
-
Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma
-
Sonoda Y, Ozawa T, Hirose Y, Aldape KD, McMahon M, Berger MS, Pieper RO (2001). Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma. Cancer Res 61, 4956-4960.
-
(2001)
Cancer Res
, vol.61
, pp. 4956-4960
-
-
Sonoda, Y.1
Ozawa, T.2
Hirose, Y.3
Aldape, K.D.4
McMahon, M.5
Berger, M.S.6
Pieper, R.O.7
-
54
-
-
33645772227
-
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
-
Sun L et al. (2006). Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 9, 287-300.
-
(2006)
Cancer Cell
, vol.9
, pp. 287-300
-
-
Sun, L.1
-
55
-
-
77955472749
-
A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis
-
Tchaicha JH, Mobley AK, Hossain MG, Aldape KD, McCarty JH (2010). A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis. Oncogene 29, 4460-4472.
-
(2010)
Oncogene
, vol.29
, pp. 4460-4472
-
-
Tchaicha, J.H.1
Mobley, A.K.2
Hossain, M.G.3
Aldape, K.D.4
McCarty, J.H.5
-
56
-
-
80054044019
-
Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by beta8 integrin
-
Tchaicha JH, Reyes SB, Shin J, Hossain MG, Lang FF, McCarty JH (2011). Glioblastoma angiogenesis and tumor cell invasiveness are differentially regulated by beta8 integrin. Cancer Res 71, 6371-6381.
-
(2011)
Cancer Res
, vol.71
, pp. 6371-6381
-
-
Tchaicha, J.H.1
Reyes, S.B.2
Shin, J.3
Hossain, M.G.4
Lang, F.F.5
McCarty, J.H.6
-
57
-
-
33644539533
-
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix
-
ten Klooster JP, Jaffer ZM, Chernoff J, Hordijk PL (2006). Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix. J Cell Biol 172, 759-769.
-
(2006)
J Cell Biol
, vol.172
, pp. 759-769
-
-
Ten Klooster, J.P.1
Jaffer, Z.M.2
Chernoff, J.3
Hordijk, P.L.4
-
58
-
-
34249856693
-
The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development
-
Tolias KF, Bikoff JB, Kane CG, Tolias CS, Hu L, Greenberg ME (2007). The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development. Proc Natl Acad Sci USA 104, 7265-7270.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 7265-7270
-
-
Tolias, K.F.1
Bikoff, J.B.2
Kane, C.G.3
Tolias, C.S.4
Hu, L.5
Greenberg, M.E.6
-
59
-
-
33750449285
-
Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage
-
Triolo D, Dina G, Lorenzetti I, Malaguti M, Morana P, Del Carro U, Comi G, Messing A, Quattrini A, Previtali SC (2006). Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage. J Cell Sci 119, 3981-3993.
-
(2006)
J Cell Sci
, vol.119
, pp. 3981-3993
-
-
Triolo, D.1
Dina, G.2
Lorenzetti, I.3
Malaguti, M.4
Morana, P.5
Del Carro, U.6
Comi, G.7
Messing, A.8
Quattrini, A.9
Previtali, S.C.10
-
60
-
-
84858277359
-
Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesis
-
Upadhyaya M, Spurlock G, Thomas L, Thomas NS, Richards M, Mautner VF, Cooper DN, Guha A, Yan J (2012). Microarray-based copy number analysis of neurofibromatosis type-1 (NF1)-associated malignant peripheral nerve sheath tumors reveals a role for Rho-GTPase pathway genes in NF1 tumorigenesis. Hum Mutat 33, 763-776.
-
(2012)
Hum Mutat
, vol.33
, pp. 763-776
-
-
Upadhyaya, M.1
Spurlock, G.2
Thomas, L.3
Thomas, N.S.4
Richards, M.5
Mautner, V.F.6
Cooper, D.N.7
Guha, A.8
Yan, J.9
-
61
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak RG et al. (2010). Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17, 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
-
62
-
-
79955007489
-
Signalling to cancer cell invasion through PAK family kinases
-
Whale A, Hashim FN, Fram S, Jones GE, Wells CM (2011). Signalling to cancer cell invasion through PAK family kinases. Front Biosci 16, 849-864.
-
(2011)
Front Biosci
, vol.16
, pp. 849-864
-
-
Whale, A.1
Hashim, F.N.2
Fram, S.3
Jones, G.E.4
Wells, C.M.5
-
63
-
-
84865306060
-
Alteration in metastasis potential and gene expression in human lung cancer cell lines by ITGB8 silencing
-
Xu Z, Wu R (2012). Alteration in metastasis potential and gene expression in human lung cancer cell lines by ITGB8 silencing. Anat Rec (Hoboken) 295, 1446-1454.
-
(2012)
Anat Rec (Hoboken
, vol.295
, pp. 1446-1454
-
-
Xu, Z.1
Wu, R.2
-
64
-
-
0037408391
-
The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI
-
Yamashita T, Tohyama M (2003). The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 6, 461-467.
-
(2003)
Nat Neurosci
, vol.6
, pp. 461-467
-
-
Yamashita, T.1
Tohyama, M.2
|