-
1
-
-
77951599543
-
Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma
-
Huse, J.T. et al. (2010) Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat. Rev. Cancer, 10, 319-331.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 319-331
-
-
Huse, J.T.1
-
2
-
-
79957926996
-
The brain tumor microenvironment
-
Charles, N.A. et al. (2011) The brain tumor microenvironment. Glia, 59, 1169-1180.
-
(2011)
Glia
, vol.59
, pp. 1169-1180
-
-
Charles, N.A.1
-
3
-
-
0036485214
-
Chemokine receptors: multifaceted therapeutic targets
-
Proudfoot, A.E. (2002) Chemokine receptors: multifaceted therapeutic targets. Nat. Rev. Immunol., 2, 106-115.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 106-115
-
-
Proudfoot, A.E.1
-
4
-
-
77953090345
-
CXCL12 (SDF-1)/CXCR4 pathway in cancer
-
Teicher, B.A. et al. (2010) CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin. Cancer Res., 16, 2927-2931.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 2927-2931
-
-
Teicher, B.A.1
-
5
-
-
0032892770
-
Cytokine regulation of CC and CXC chemokine expression by human astrocytes
-
Oh, J.W. et al. (1999) Cytokine regulation of CC and CXC chemokine expression by human astrocytes. J. Neurovirol., 5, 82-94.
-
(1999)
J. Neurovirol.
, vol.5
, pp. 82-94
-
-
Oh, J.W.1
-
6
-
-
0036206606
-
MCP-1 expression in CNS-1 astrocytoma cells: implications for macrophage infiltration into tumors in vivo
-
Kielian, T. et al. (2002) MCP-1 expression in CNS-1 astrocytoma cells: implications for macrophage infiltration into tumors in vivo. J. Neurooncol., 56, 1-12.
-
(2002)
J. Neurooncol.
, vol.56
, pp. 1-12
-
-
Kielian, T.1
-
7
-
-
0030856117
-
Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis
-
Desbaillets, I. et al. (1997) Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis. J. Exp. Med., 186, 1201-1212.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1201-1212
-
-
Desbaillets, I.1
-
8
-
-
4344581339
-
CXCL12 in malignant glial tumors: a possible role in angiogenesis and cross-talk between endothelial and tumoral cells
-
Salmaggi, A. et al. (2004) CXCL12 in malignant glial tumors: a possible role in angiogenesis and cross-talk between endothelial and tumoral cells. J. Neurooncol., 67, 305-317.
-
(2004)
J. Neurooncol.
, vol.67
, pp. 305-317
-
-
Salmaggi, A.1
-
9
-
-
33746925232
-
Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration
-
Bajetto, A. et al. (2006) Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration. Neurochem. Int., 49, 423-432.
-
(2006)
Neurochem. Int.
, vol.49
, pp. 423-432
-
-
Bajetto, A.1
-
10
-
-
80052092543
-
CXCL12/CXCR4 signaling in malignant brain tumors: a potential pharmacological therapeutic target
-
Terasaki, M. et al. (2011) CXCL12/CXCR4 signaling in malignant brain tumors: a potential pharmacological therapeutic target. Brain Tumor Pathol., 28, 89-97.
-
(2011)
Brain Tumor Pathol.
, vol.28
, pp. 89-97
-
-
Terasaki, M.1
-
11
-
-
0033848994
-
CXC chemokines in angiogenesis
-
Belperio, J.A. et al. (2000) CXC chemokines in angiogenesis. J. Leukoc. Biol., 68, 1-8.
-
(2000)
J. Leukoc. Biol.
, vol.68
, pp. 1-8
-
-
Belperio, J.A.1
-
12
-
-
27944486755
-
The chemokine GRO-alpha (CXCL1) confers increased tumorigenicity to glioma cells
-
Zhou, Y. et al. (2005) The chemokine GRO-alpha (CXCL1) confers increased tumorigenicity to glioma cells. Carcinogenesis, 26, 2058-2068.
-
(2005)
Carcinogenesis
, vol.26
, pp. 2058-2068
-
-
Zhou, Y.1
-
13
-
-
77955085751
-
Chemokines and glioma: invasion and more
-
Sciume, G. et al. (2010) Chemokines and glioma: invasion and more. J. Neuroimmunol., 224, 8-12.
-
(2010)
J. Neuroimmunol.
, vol.224
, pp. 8-12
-
-
Sciume, G.1
-
14
-
-
0037147223
-
CXCR4 is a major chemokine receptor on glioma cells and mediates their survival
-
Zhou, Y. et al. (2002) CXCR4 is a major chemokine receptor on glioma cells and mediates their survival. J. Biol. Chem., 277, 49481-49487.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49481-49487
-
-
Zhou, Y.1
-
15
-
-
27944455701
-
The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase
-
Zhang, J. et al. (2005) The chemokine stromal cell derived factor-1 (CXCL12) promotes glioma invasiveness through MT2-matrix metalloproteinase. Carcinogenesis, 26, 2069-2077.
-
(2005)
Carcinogenesis
, vol.26
, pp. 2069-2077
-
-
Zhang, J.1
-
16
-
-
33748532939
-
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
-
Hussain, S.F. et al. (2006) The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses. Neuro-oncol., 8, 261-279.
-
(2006)
Neuro-oncol.
, vol.8
, pp. 261-279
-
-
Hussain, S.F.1
-
17
-
-
0021206304
-
Mononuclear lymphoid populations infiltrating the microenvironment of primary CNS tumors. Characterization of cell subsets with monoclonal antibodies
-
von Hanwehr et al. (1984) Mononuclear lymphoid populations infiltrating the microenvironment of primary CNS tumors. Characterization of cell subsets with monoclonal antibodies. J. Neurosurg., 60, 1138-1147.
-
(1984)
J. Neurosurg.
, vol.60
, pp. 1138-1147
-
-
von Hanwehr1
-
18
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Ben-Neriah, Y. et al. (2011) Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat. Immunol., 12, 715-723.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
-
19
-
-
0038719646
-
Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade
-
Le, D.M. et al. (2003) Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade. J. Neurosci., 23, 4034-4043.
-
(2003)
J. Neurosci.
, vol.23
, pp. 4034-4043
-
-
Le, D.M.1
-
20
-
-
33846253207
-
Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12
-
Sarkar, S. et al. (2006) Tenascin-C stimulates glioma cell invasion through matrix metalloproteinase-12. Cancer Res., 66, 11771-11780.
-
(2006)
Cancer Res.
, vol.66
, pp. 11771-11780
-
-
Sarkar, S.1
-
21
-
-
0034727624
-
Interferon beta-1b increases interleukin-10 in a model of T cell-microglia interaction: relevance to MS
-
Chabot, S. et al. (2000) Interferon beta-1b increases interleukin-10 in a model of T cell-microglia interaction: relevance to MS. Neurology, 55, 1497-1505.
-
(2000)
Neurology
, vol.55
, pp. 1497-1505
-
-
Chabot, S.1
-
22
-
-
17844397949
-
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
-
Brat, D.J. et al. (2005) The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro-oncol., 7, 122-133.
-
(2005)
Neuro-oncol.
, vol.7
, pp. 122-133
-
-
Brat, D.J.1
-
23
-
-
78651275992
-
Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB
-
Sun, S. et al. (2011) Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-κB. J. Neurooncol., 101, 1-14.
-
(2011)
J. Neurooncol.
, vol.101
, pp. 1-14
-
-
Sun, S.1
-
24
-
-
44949176222
-
Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness
-
de la Iglesia, N. et al. (2008) Deregulation of a STAT3-interleukin 8 signaling pathway promotes human glioblastoma cell proliferation and invasiveness. J. Neurosci., 28, 5870-5878.
-
(2008)
J. Neurosci.
, vol.28
, pp. 5870-5878
-
-
de la Iglesia, N.1
-
25
-
-
4544233936
-
Expression of keratinocyte growth factor/fibroblast growth factor-7 and its receptor in human lung cancer: correlation with tumour proliferative activity and patient prognosis
-
Yamayoshi, T. et al. (2004) Expression of keratinocyte growth factor/fibroblast growth factor-7 and its receptor in human lung cancer: correlation with tumour proliferative activity and patient prognosis. J. Pathol., 204, 110-118.
-
(2004)
J. Pathol.
, vol.204
, pp. 110-118
-
-
Yamayoshi, T.1
-
26
-
-
34250352380
-
Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors
-
Niu, J. et al. (2007) Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J. Biol. Chem., 282, 6001-6011.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 6001-6011
-
-
Niu, J.1
-
27
-
-
33745288597
-
Keratinocyte growth factor expression and activity in cancer: implications for use in patients with solid tumors
-
Finch, P.W. et al. (2006) Keratinocyte growth factor expression and activity in cancer: implications for use in patients with solid tumors. J. Natl Cancer Inst., 98, 812-824.
-
(2006)
J. Natl Cancer Inst.
, vol.98
, pp. 812-824
-
-
Finch, P.W.1
-
28
-
-
33645830089
-
Enhanced motility of KGF-transfected breast cancer cells
-
Zang, X.P. et al. (2006) Enhanced motility of KGF-transfected breast cancer cells. Anticancer Res., 26, 961-966.
-
(2006)
Anticancer Res.
, vol.26
, pp. 961-966
-
-
Zang, X.P.1
-
29
-
-
35148871720
-
Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses
-
Fulci, G. et al. (2007) Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res., 67, 9398-9406.
-
(2007)
Cancer Res.
, vol.67
, pp. 9398-9406
-
-
Fulci, G.1
-
30
-
-
0035901090
-
Inflammation and cancer: back to Virchow?
-
Balkwill, F. et al. (2001) Inflammation and cancer: back to Virchow?. Lancet, 357, 539-545.
-
(2001)
Lancet
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
-
31
-
-
79958189212
-
The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling
-
Ping, Y.F. et al. (2011) The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling. J. Pathol., 224, 344-354.
-
(2011)
J. Pathol.
, vol.224
, pp. 344-354
-
-
Ping, Y.F.1
-
32
-
-
78751527149
-
Expression of the new CXCL12 receptor, CXCR7, in gliomas
-
Calatozzolo, C. et al. (2011) Expression of the new CXCL12 receptor, CXCR7, in gliomas. Cancer Biol. Ther., 11, 242-253.
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 242-253
-
-
Calatozzolo, C.1
-
33
-
-
0034872239
-
Interleukin-6 overexpression as a marker of malignancy in human gliomas
-
Rolhion, C. et al. (2001) Interleukin-6 overexpression as a marker of malignancy in human gliomas. J. Neurosurg., 94, 97-101.
-
(2001)
J. Neurosurg.
, vol.94
, pp. 97-101
-
-
Rolhion, C.1
-
34
-
-
0035902847
-
IL-6 gene amplification and expression in human glioblastomas
-
Tchirkov, A. et al. (2001) IL-6 gene amplification and expression in human glioblastomas. Br. J. Cancer, 85, 518-522.
-
(2001)
Br. J. Cancer
, vol.85
, pp. 518-522
-
-
Tchirkov, A.1
-
35
-
-
79960007941
-
Cytokine networks in glioma
-
Iwami, K. et al. (2011) Cytokine networks in glioma. Neurosurg. Rev., 34, 253-264.
-
(2011)
Neurosurg. Rev.
, vol.34
, pp. 253-264
-
-
Iwami, K.1
-
36
-
-
77951735629
-
IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1
-
Li, R. et al. (2010) IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1. Oncol. Rep., 23, 1553-1559.
-
(2010)
Oncol. Rep.
, vol.23
, pp. 1553-1559
-
-
Li, R.1
-
37
-
-
70350223977
-
Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth
-
Wang, H. et al. (2009) Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells, 27, 2393-2404.
-
(2009)
Stem Cells
, vol.27
, pp. 2393-2404
-
-
Wang, H.1
-
38
-
-
77951735629
-
IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1
-
Li, R. et al. (2010) IL-6 augments the invasiveness of U87MG human glioblastoma multiforme cells via up-regulation of MMP-2 and fascin-1. Oncol. Rep., 23, 1553-1559.
-
(2010)
Oncol. Rep.
, vol.23
, pp. 1553-1559
-
-
Li, R.1
-
39
-
-
0036850131
-
Microglia in brain tumors
-
Graeber, M.B. et al. (2002) Microglia in brain tumors. Glia, 40, 252-259.
-
(2002)
Glia
, vol.40
, pp. 252-259
-
-
Graeber, M.B.1
-
40
-
-
71749096751
-
Induction of glioma apoptosis by microgliasecreted molecules: the role of nitric oxide and cathepsin B
-
Hwang, S.Y. et al. (2009) Induction of glioma apoptosis by microgliasecreted molecules: the role of nitric oxide and cathepsin B. Biochim. Biophys. Acta, 1793, 1656-1668.
-
(2009)
Biochim. Biophys. Acta
, vol.1793
, pp. 1656-1668
-
-
Hwang, S.Y.1
-
41
-
-
65249134734
-
TNF-alpha- and TRAIL-resistant glioma cells undergo autophagy-dependent cell death induced by activated microglia
-
Mora, R. et al. (2009) TNF-alpha- and TRAIL-resistant glioma cells undergo autophagy-dependent cell death induced by activated microglia. Glia, 57, 561-581.
-
(2009)
Glia
, vol.57
, pp. 561-581
-
-
Mora, R.1
-
42
-
-
0031045382
-
Microglia-derived cytotoxic factors. Part I: inhibition of tumor cell growth in vitro
-
Rosales, A.A. et al. (1997) Microglia-derived cytotoxic factors. Part I: inhibition of tumor cell growth in vitro. Brain Res., 748, 195-204.
-
(1997)
Brain Res.
, vol.748
, pp. 195-204
-
-
Rosales, A.A.1
-
43
-
-
78650341415
-
Nitric oxide-mediated tumoricidal activity of murine microglial cells
-
Brantley, E.C. et al. (2010) Nitric oxide-mediated tumoricidal activity of murine microglial cells. Transl. Oncol., 3, 380-388.
-
(2010)
Transl. Oncol.
, vol.3
, pp. 380-388
-
-
Brantley, E.C.1
-
44
-
-
70349097179
-
Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice
-
Zhang, L. et al. (2009) Stat3 inhibition activates tumor macrophages and abrogates glioma growth in mice. Glia, 57, 1458-1467.
-
(2009)
Glia
, vol.57
, pp. 1458-1467
-
-
Zhang, L.1
-
45
-
-
34548760331
-
Increased glioma growth in mice depleted of macrophages
-
Galarneau, H. et al. (2007) Increased glioma growth in mice depleted of macrophages. Cancer Res., 67, 8874-8881.
-
(2007)
Cancer Res.
, vol.67
, pp. 8874-8881
-
-
Galarneau, H.1
-
46
-
-
72449154567
-
The role of microglia in central nervous system immunity and glioma immunology
-
Yang, I. et al. (2010) The role of microglia in central nervous system immunity and glioma immunology. J. Clin. Neurosci., 17, 6-10.
-
(2010)
J. Clin. Neurosci.
, vol.17
, pp. 6-10
-
-
Yang, I.1
-
47
-
-
78049270536
-
Glioma cancer stem cells induce immunosuppressive macrophages/microglia
-
Wu, A. et al. (2010) Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro-oncol., 12, 1113-1125.
-
(2010)
Neuro-oncol.
, vol.12
, pp. 1113-1125
-
-
Wu, A.1
-
48
-
-
0041835842
-
Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas
-
Platten, M. et al. (2003) Monocyte chemoattractant protein-1 increases microglial infiltration and aggressiveness of gliomas. Ann. Neurol., 54, 388-392.
-
(2003)
Ann. Neurol.
, vol.54
, pp. 388-392
-
-
Platten, M.1
-
49
-
-
54749092522
-
Flt-1 signaling in macrophages promotes glioma growth in vivo
-
Kerber, M. et al. (2008) Flt-1 signaling in macrophages promotes glioma growth in vivo. Cancer Res., 68, 7342-7351.
-
(2008)
Cancer Res.
, vol.68
, pp. 7342-7351
-
-
Kerber, M.1
-
50
-
-
68149169092
-
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion
-
Markovic, D.S. et al. (2009) Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion. Proc. Natl Acad. Sci. USA, 106, 12530-12535.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 12530-12535
-
-
Markovic, D.S.1
-
51
-
-
78751700548
-
Microglia/macrophages promote glioma progression
-
Zhai, H. et al. (2011) Microglia/macrophages promote glioma progression. Glia, 59, 472-485.
-
(2011)
Glia
, vol.59
, pp. 472-485
-
-
Zhai, H.1
-
52
-
-
0036946575
-
Microglia promote glioma migration
-
Bettinger, I. et al. (2002) Microglia promote glioma migration. Acta Neuropathol., 103, 351-355.
-
(2002)
Acta Neuropathol.
, vol.103
, pp. 351-355
-
-
Bettinger, I.1
-
53
-
-
33846567515
-
The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A
-
Sliwa, M. et al. (2007) The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A. Brain, 130, 476-489.
-
(2007)
Brain
, vol.130
, pp. 476-489
-
-
Sliwa, M.1
-
54
-
-
24644490056
-
Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2
-
Markovic, D.S. et al. (2005) Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J. Neuropathol. Exp. Neurol., 64, 754-762.
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 754-762
-
-
Markovic, D.S.1
-
55
-
-
33847723000
-
Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia
-
Nuttall, R.K. et al. (2007) Metalloproteinases are enriched in microglia compared with leukocytes and they regulate cytokine levels in activated microglia. Glia, 55, 516-526.
-
(2007)
Glia
, vol.55
, pp. 516-526
-
-
Nuttall, R.K.1
-
56
-
-
79954741725
-
Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression
-
Markovic, D.S. et al. (2011) Minocycline reduces glioma expansion and invasion by attenuating microglial MT1-MMP expression. Brain Behav. Immun., 25, 624-628.
-
(2011)
Brain Behav. Immun.
, vol.25
, pp. 624-628
-
-
Markovic, D.S.1
|