RNAi-mediated inhibition of presenilin 2 inhibits glioma cell growth and invasion and is involved in the regulation of Nrg1/ErbB signaling

Neuro-Oncology

Volumn 14, Issue 8, 2012, Pages 994-1006

  Liu, Bei ^a   Wang, Liang ^a   Shen, Liang Liang ^b   Shen, Ming Zhi ^d   Guo, Xiao Dong ^e   Wang, Tao ^b   Liang, Qin Chuan ^a   Wang, Chao ^a   Zheng, Jun ^c   Li, Yi ^a   Jia, Lin Tao ^b   Zhang, Hua ^a   Gao, Guo Dong ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c XI'AN JIAOTONG UNIVERSITY   (China)

^d FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^e Department of Neurosurgery   (China)

Author keywords

glioma; invasion; Nrg1 ErbB; presenilin 2; proliferation; RNAi

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; NEU DIFFERENTIATION FACTOR; PRESENILIN 2; SHORT HAIRPIN RNA;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL GROWTH; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; COLONY FORMATION; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CELL PROLIFERATION; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEUREGULIN-1; POLYMERASE CHAIN REACTION; PRESENILIN-2; RECEPTOR, ERBB-2; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84864721664     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nos138     Document Type: Article

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