-
1
-
-
0035469483
-
Current and future developments in the use of temozolomide for the treatment of brain tumours
-
doi: 10.1016/S1470-2045(01)00489-2
-
Stupp R, Gander M, Leyvraz S, Newlands E (2001) Current and future developments in the use of temozolomide for the treatment of brain tumours. Lancet Oncol 2:552-560. doi: 10.1016/S1470-2045(01)00489-2
-
(2001)
Lancet Oncol
, vol.2
, pp. 552-560
-
-
Stupp, R.1
Gander, M.2
Leyvraz, S.3
Newlands, E.4
-
2
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
doi: 10.1056/NEJMoa043330
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ et al (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987-996. doi: 10.1056/NEJMoa043330
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
-
3
-
-
0032850844
-
The extracellular matrix of glioma: Modulation of cell function
-
doi: 10.1097/00005072-199910000-00001
-
Gladson CL (1999) The extracellular matrix of glioma: Modulation of cell function. J Neuropathol Exp Neurol 58:1029-1040. doi: 10.1097/ 00005072-199910000-00001
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1029-1040
-
-
Gladson, C.L.1
-
4
-
-
0035076818
-
Glial tumor invasion: A role for the upregulation and cleavage of BEHAB/ Brevican
-
Nutt CL, Matthews RT, Hockfield S (2001) Glial tumor invasion: A role for the upregulation and cleavage of BEHAB/Brevican. Neuroscientist 7:113-122
-
(2001)
Neuroscientist
, vol.7
, pp. 113-122
-
-
Nutt, C.L.1
Matthews, R.T.2
Hockfield, S.3
-
5
-
-
13444275480
-
Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion
-
doi: 10.1016/j.biocel.2004.01.013
-
Bellail AC, Hunter SB, Brat DJ, Tan C, Van Meir EG (2004) Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. Int J Biochem Cell Biol 36:1046-1069. doi: 10.1016/ j.biocel.2004.01.013
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1046-1069
-
-
Bellail, A.C.1
Hunter, S.B.2
Brat, D.J.3
Tan, C.4
Van Meir, E.G.5
-
6
-
-
0034755942
-
Molecular complexity and dynamics of cell-matrix adhesions
-
Zamir E, Geiger B (2001) Molecular complexity and dynamics of cell-matrix adhesions. J Cell Sci 114:3583-3590
-
(2001)
J Cell Sci
, vol.114
, pp. 3583-3590
-
-
Zamir, E.1
Geiger, B.2
-
7
-
-
0842281489
-
Multiple connections link FAK to cell motility and invasion
-
doi: 10.1016/j.gde.2003.12.002
-
Schlaepfer DD, Mitra SK (2004) Multiple connections link FAK to cell motility and invasion. Curr Opin Genet Dev 14:92-101. doi: 10.1016/ j.gde.2003.12.002
-
(2004)
Curr Opin Genet Dev
, vol.14
, pp. 92-101
-
-
Schlaepfer, D.D.1
Mitra, S.K.2
-
8
-
-
0034232062
-
Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response
-
doi: 10.1038/76882
-
Guinamard R, Okigaki M, Schlessinger J, Ravetch JV (2000) Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response. Nat Immunol 1:31-36. doi: 10.1038/76882
-
(2000)
Nat Immunol
, vol.1
, pp. 31-36
-
-
Guinamard, R.1
Okigaki, M.2
Schlessinger, J.3
Ravetch, J.V.4
-
9
-
-
0141591532
-
Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration
-
doi: 10.1073/pnas.1834348100
-
Okigaki M, Davis C, Falasca M, Harroch S, Felsenfeld DP, Sheetz MP et al (2003) Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration. Proc Natl Acad Sci USA 100:10740-10745. doi: 10.1073/pnas.1834348100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10740-10745
-
-
Okigaki, M.1
Davis, C.2
Falasca, M.3
Harroch, S.4
Felsenfeld, D.P.5
Sheetz, M.P.6
-
10
-
-
0034851713
-
Inhibition of PYK2-induced actin cytoskeleton reorganization, PYK2 autophosphorylation and focal adhesion targeting by FAK
-
Du QS, Ren XR, Xie Y, Wang Q, Mei L, Xiong WC (2001) Inhibition of PYK2-induced actin cytoskeleton reorganization, PYK2 autophosphorylation and focal adhesion targeting by FAK. J Cell Sci 114:2977-2987
-
(2001)
J Cell Sci
, vol.114
, pp. 2977-2987
-
-
Du, Q.S.1
Ren, X.R.2
Xie, Y.3
Wang, Q.4
Mei, L.5
Xiong, W.C.6
-
11
-
-
0033833068
-
Pyk2 and FAK differentially regulate progression of the cell cycle
-
Zhao J, Zheng C, Guan J (2000) Pyk2 and FAK differentially regulate progression of the cell cycle. J Cell Sci 113:3063-3072
-
(2000)
J Cell Sci
, vol.113
, pp. 3063-3072
-
-
Zhao, J.1
Zheng, C.2
Guan, J.3
-
12
-
-
0032531732
-
Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK(-) cell migration
-
doi: 10.1093/emboj/17.20.5933
-
Sieg DJ, Ilic D, Jones KC, Damsky CH, Hunter T, Schlaepfer DD (1998) Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK(-) cell migration. EMBO J 17:5933-5947. doi: 10.1093/emboj/17.20.5933
-
(1998)
EMBO J
, vol.17
, pp. 5933-5947
-
-
Sieg, D.J.1
Ilic, D.2
Jones, K.C.3
Damsky, C.H.4
Hunter, T.5
Schlaepfer, D.D.6
-
13
-
-
0031685309
-
Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK
-
doi: 10.1016/S0014-5793(98)00862-X
-
Ueki K, Mimura T, Nakamoto T, Sasaki T, Aizawa S, Hirai H et al (1998) Integrin-mediated signal transduction in cells lacking focal adhesion kinase p125FAK. FEBS Lett 432:197-201. doi: 10.1016/S0014-5793(98)00862-X
-
(1998)
FEBS Lett
, vol.432
, pp. 197-201
-
-
Ueki, K.1
Mimura, T.2
Nakamoto, T.3
Sasaki, T.4
Aizawa, S.5
Hirai, H.6
-
14
-
-
0034532347
-
p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo
-
Wang D, Grammer JR, Cobbs CS, Stewart JE Jr, Liu Z, Rhoden R et al (2000) p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo. J Cell Sci 113:4221-4230
-
(2000)
J Cell Sci
, vol.113
, pp. 4221-4230
-
-
Wang, D.1
Grammer, J.R.2
Cobbs, C.S.3
Stewart Jr., J.E.4
Liu, Z.5
Rhoden, R.6
-
15
-
-
2542511549
-
Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells
-
doi: 10.1038/sj.onc.1207541
-
Hecker TP, Ding Q, Rege TA, Hanks SK, Gladson CL (2004) Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells. Oncogene 23:3962-3971. doi: 10.1038/sj.onc.1207541
-
(2004)
Oncogene
, vol.23
, pp. 3962-3971
-
-
Hecker, T.P.1
Ding, Q.2
Rege, T.A.3
Hanks, S.K.4
Gladson, C.L.5
-
16
-
-
20344393365
-
The tyrosine kinase pyk2 promotes migration and invasion of glioma cells
-
doi: 10.1593/neo.04712
-
Lipinski CA, Tran NL, Menashi E, Rohl C, Kloss J, Bay RC et al (2005) The tyrosine kinase pyk2 promotes migration and invasion of glioma cells. Neoplasia 7:435-445. doi: 10.1593/neo.04712
-
(2005)
Neoplasia
, vol.7
, pp. 435-445
-
-
Lipinski, C.A.1
Tran, N.L.2
Menashi, E.3
Rohl, C.4
Kloss, J.5
Bay, R.C.6
-
17
-
-
13444294190
-
Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets
-
doi: 10.1593/neo.04535
-
Hoelzinger DB, Mariani L, Weis J, Woyke T, Berens TJ, McDonough WS et al (2005) Gene expression profile of glioblastoma multiforme invasive phenotype points to new therapeutic targets. Neoplasia 7:7-16. doi: 10.1593/neo.04535
-
(2005)
Neoplasia
, vol.7
, pp. 7-16
-
-
Hoelzinger, D.B.1
Mariani, L.2
Weis, J.3
Woyke, T.4
Berens, T.J.5
McDonough, W.S.6
-
18
-
-
4444257383
-
Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas
-
doi: 10.1007/s00401-004-0886-3
-
Gutenberg A, Bruck W, Buchfelder M, Ludwig HC (2004) Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas. Acta Neuropathol 108:224-230. doi: 10.1007/s00401-004-0886-3
-
(2004)
Acta Neuropathol
, vol.108
, pp. 224-230
-
-
Gutenberg, A.1
Bruck, W.2
Buchfelder, M.3
Ludwig, H.C.4
-
19
-
-
31744445721
-
A versatile tool for conditional gene expression and knockdown
-
doi: 10.1038/nmeth846
-
Szulc J, Wiznerowicz M, Sauvain MO, Trono D, Aebischer P (2006) A versatile tool for conditional gene expression and knockdown. Nat Methods 3:109-116. doi: 10.1038/nmeth846
-
(2006)
Nat Methods
, vol.3
, pp. 109-116
-
-
Szulc, J.1
Wiznerowicz, M.2
Sauvain, M.O.3
Trono, D.4
Aebischer, P.5
-
20
-
-
33748616273
-
Critical role of the FERM domain in Pyk2 stimulated glioma cell migration
-
doi: 10.1016/j.bbrc.2006.08.134
-
Lipinski CA, Tran NL, Dooley A, Pang YP, Rohl C, Kloss J et al (2006) Critical role of the FERM domain in Pyk2 stimulated glioma cell migration. Biochem Biophys Res Commun 349:939-947. doi: 10.1016/ j.bbrc.2006.08.134
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 939-947
-
-
Lipinski, C.A.1
Tran, N.L.2
Dooley, A.3
Pang, Y.P.4
Rohl, C.5
Kloss, J.6
-
21
-
-
0043210428
-
Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
-
doi: 10.1128/JVI.77.16.8957-8951.2003
-
Wiznerowicz M, Trono D (2003) Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol 77:8957-8961. doi: 10.1128/JVI.77.16.8957-8951.2003
-
(2003)
J Virol
, vol.77
, pp. 8957-8961
-
-
Wiznerowicz, M.1
Trono, D.2
-
22
-
-
0037359549
-
Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation
-
Lipinski CA, Tran NL, Bay C, Kloss J, McDonough WS, Beaudry C et al (2003) Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation. Mol Cancer Res 1:323-332
-
(2003)
Mol Cancer Res
, vol.1
, pp. 323-332
-
-
Lipinski, C.A.1
Tran, N.L.2
Bay, C.3
Kloss, J.4
McDonough, W.S.5
Beaudry, C.6
-
23
-
-
0032576547
-
Regulation of the cell cycle by focal adhesion kinase
-
doi: 10.1083/jcb.143.7.1997
-
Zhao JH, Reiske H, Guan JL (1998) Regulation of the cell cycle by focal adhesion kinase. J Cell Biol 143:1997-2008. doi: 10.1083/jcb.143.7.1997
-
(1998)
J Cell Biol
, vol.143
, pp. 1997-2008
-
-
Zhao, J.H.1
Reiske, H.2
Guan, J.L.3
-
24
-
-
34447538483
-
Cellular characterization of a novel focal adhesion kinase inhibitor
-
doi: 10.1074/jbc.M606695200
-
Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C et al (2007) Cellular characterization of a novel focal adhesion kinase inhibitor. J Biol Chem 282:14845-14852. doi: 10.1074/jbc.M606695200
-
(2007)
J Biol Chem
, vol.282
, pp. 14845-14852
-
-
Slack-Davis, J.K.1
Martin, K.H.2
Tilghman, R.W.3
Iwanicki, M.4
Ung, E.J.5
Autry, C.6
-
25
-
-
34250163937
-
A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth
-
doi: 10.1002/mc.20297
-
Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D et al (2007) A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. Mol Carcinog 46:488-496. doi: 10.1002/mc.20297
-
(2007)
Mol Carcinog
, vol.46
, pp. 488-496
-
-
Shi, Q.1
Hjelmeland, A.B.2
Keir, S.T.3
Song, L.4
Wickman, S.5
Jackson, D.6
-
26
-
-
41149130736
-
Protein-tyrosine kinase CAKβ/PYK2 is activated by binding Ca2+/ calmodulin to FERM F2 α2 helix and thus forming its dimer
-
doi: 10.1042/BJ20070665
-
Kohno T, Matsuda E, Sasaki H, Sasaki T (2008) Protein-tyrosine kinase CAKβ/PYK2 is activated by binding Ca2+/calmodulin to FERM F2 α2 helix and thus forming its dimer. Biochem J 410:513-523. doi: 10.1042/BJ20070665
-
(2008)
Biochem J
, vol.410
, pp. 513-523
-
-
Kohno, T.1
Matsuda, E.2
Sasaki, H.3
Sasaki, T.4
-
27
-
-
4043054389
-
RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner
-
doi: 10.1074/jbc.M313527200
-
Park SY, Avraham HK, Avraham S (2004) RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner. J Biol Chem 279:33315-33322. doi: 10.1074/jbc.M313527200
-
(2004)
J Biol Chem
, vol.279
, pp. 33315-33322
-
-
Park, S.Y.1
Avraham, H.K.2
Avraham, S.3
-
28
-
-
0037388679
-
Protein-protein interactions as a target for drugs in proteomics
-
doi: 10.1002/pmic.200390053
-
Archakov AI, Govorun VM, Dubanov AV, Ivanov YD, Veselovsky AV, Lewi P et al (2003) Protein-protein interactions as a target for drugs in proteomics. Proteomics 3:380-391. doi: 10.1002/pmic.200390053
-
(2003)
Proteomics
, vol.3
, pp. 380-391
-
-
Archakov, A.I.1
Govorun, V.M.2
Dubanov, A.V.3
Ivanov, Y.D.4
Veselovsky, A.V.5
Lewi, P.6
-
29
-
-
0029787294
-
Dichotomy of astrocytoma migration and proliferation
-
doi:. 10.1002/ (SICI)1097-0215(19960717)67:2<275::AID-IJC20>3.0.CO;2-9
-
Giese A, Loo MA, Tran N, Haskett D, Coons SW, Berens ME (1996) Dichotomy of astrocytoma migration and proliferation. Int J Cancer 67:275-282. doi: 10.1002/ (SICI)1097-0215(19960717)67:2<275::AID-IJC20>3.0.CO;2-9
-
(1996)
Int J Cancer
, vol.67
, pp. 275-282
-
-
Giese, A.1
Loo, M.A.2
Tran, N.3
Haskett, D.4
Coons, S.W.5
Berens, M.E.6
-
30
-
-
0038048467
-
Testing the "go or grow" hypothesis in human medulloblastoma cell lines in two and three dimensions
-
doi: 10.1227/01.NEU.0000072442.26349.14
-
Corcoran A, Del Maestro RF (2003) Testing the "go or grow" hypothesis in human medulloblastoma cell lines in two and three dimensions. Neurosurgery 53:174-184. doi: 10.1227/ 01.NEU.0000072442.26349.14
-
(2003)
Neurosurgery
, vol.53
, pp. 174-184
-
-
Corcoran, A.1
Del Maestro, R.F.2
-
31
-
-
23044442713
-
Proliferation and invasion: Plasticity in tumor cells
-
doi: 10.1073/pnas.0504367102
-
Gao CF, Xie Q, Su YL, Koeman J, Khoo SK, Gustafson M et al (2005) Proliferation and invasion: Plasticity in tumor cells. Proc Natl Acad Sci USA 102:10528-10533. doi: 10.1073/pnas.0504367102
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10528-10533
-
-
Gao, C.F.1
Xie, Q.2
Su, Y.L.3
Koeman, J.4
Khoo, S.K.5
Gustafson, M.6
-
32
-
-
17844399776
-
Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme
-
doi: 10.1215/S1152851704000821
-
Giannini C, Sarkaria JN, Saito A, Uhm JH, Galanis E, Carlson BL et al (2005) Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme. Neuro-oncol 7:164-176. doi: 10.1215/S1152851704000821
-
(2005)
Neuro-oncol
, vol.7
, pp. 164-176
-
-
Giannini, C.1
Sarkaria, J.N.2
Saito, A.3
Uhm, J.H.4
Galanis, E.5
Carlson, B.L.6
|