Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor

Molecular Cancer

Volumn 10, Issue , 2011, Pages

  Raghu, Hari ^a   Gondi, Christopher S ^a   Dinh, Dzung H ^a   Gujrati, Meena ^a   Rao, Jasti S ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

Glioblastoma; Invasion; Notch 1 receptor; Upa upar

Indexed keywords

FIBRINOGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH1 RECEPTOR; SHORT HAIRPIN RNA; UROKINASE; UROKINASE RECEPTOR; CALCIUM BINDING PROTEIN; MEMBRANE PROTEIN; PROTEIN; SERRATE PROTEINS; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INVASION; CELL ANCHORAGE; CELL MIGRATION; DOWN REGULATION; GENETIC TRANSCRIPTION; GLIOBLASTOMA; LYSOSOME; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; STRUCTURE ANALYSIS; TUMOR XENOGRAFT; ZYMOGRAPHY; ANIMAL; BRAIN TUMOR; CANCER TRANSPLANTATION; CELL ADHESION; CELL NUCLEUS; GENE EXPRESSION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; NUDE MOUSE; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TISSUE MICROARRAY; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANIMALS; BRAIN NEOPLASMS; CALCIUM-BINDING PROTEINS; CELL ADHESION; CELL LINE, TUMOR; CELL NUCLEUS; GENE EXPRESSION; GENE KNOCKDOWN TECHNIQUES; GLIOBLASTOMA; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTOR, NOTCH1; RECEPTORS, UROKINASE PLASMINOGEN ACTIVATOR; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TISSUE ARRAY ANALYSIS; TRANSCRIPTIONAL ACTIVATION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 80054089654     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-10-130     Document Type: Article

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