메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages

Deltex-1 Activates Mitotic Signaling and Proliferation and Increases the Clonogenic and Invasive Potential of U373 and LN18 Glioblastoma Cells and Correlates with Patient Survival

Author keywords

[No Author keywords available]

Indexed keywords

DELTEX 1; MICRORNA 21; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; UNCLASSIFIED DRUG;

EID: 84874354425     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057793     Document Type: Article
Times cited : (39)

References (56)
  • 1
    • 20444456659 scopus 로고    scopus 로고
    • The role of radio- and chemotherapy in glioblastoma
    • Stupp R, Weber DC, (2005) The role of radio- and chemotherapy in glioblastoma. Onkologie 28: 315-317.
    • (2005) Onkologie , vol.28 , pp. 315-317
    • Stupp, R.1    Weber, D.C.2
  • 2
    • 14844330067 scopus 로고    scopus 로고
    • Years of life lost (YLL) from cancer is an important measure of population burden--and should be considered when allocating research funds
    • Burnet NG, Jefferies SJ, Benson RJ, Hunt DP, Treasure FP, (2005) Years of life lost (YLL) from cancer is an important measure of population burden--and should be considered when allocating research funds. Br J Cancer 92: 241-245.
    • (2005) Br J Cancer , vol.92 , pp. 241-245
    • Burnet, N.G.1    Jefferies, S.J.2    Benson, R.J.3    Hunt, D.P.4    Treasure, F.P.5
  • 3
    • 67749093259 scopus 로고    scopus 로고
    • Crosstalk of Notch with p53 and p63 in cancer growth control
    • Dotto GP, (2009) Crosstalk of Notch with p53 and p63 in cancer growth control. Nat Rev Cancer 9: 587-595.
    • (2009) Nat Rev Cancer , vol.9 , pp. 587-595
    • Dotto, G.P.1
  • 4
    • 20144387679 scopus 로고    scopus 로고
    • Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation
    • Purow BW, Haque RM, Noel MW, Su Q, Burdick MJ, et al. (2005) Expression of Notch-1 and its ligands, Delta-like-1 and Jagged-1, is critical for glioma cell survival and proliferation. Cancer Res 65: 2353-2363.
    • (2005) Cancer Res , vol.65 , pp. 2353-2363
    • Purow, B.W.1    Haque, R.M.2    Noel, M.W.3    Su, Q.4    Burdick, M.J.5
  • 5
    • 84892545399 scopus 로고    scopus 로고
    • Notch1 promotes glioma cell migration and invasion by stimulating beta-catenin and NF-kappaB signaling via AKT activation
    • Zhang X, Chen T, Zhang J, Mao Q, Li S, et al. (2011) Notch1 promotes glioma cell migration and invasion by stimulating beta-catenin and NF-kappaB signaling via AKT activation. Cancer Sci.
    • (2011) Cancer Sci.
    • Zhang, X.1    Chen, T.2    Zhang, J.3    Mao, Q.4    Li, S.5
  • 7
    • 77956294442 scopus 로고    scopus 로고
    • Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence
    • Gilbert CA, Daou MC, Moser RP, Ross AH, (2010) Gamma-secretase inhibitors enhance temozolomide treatment of human gliomas by inhibiting neurosphere repopulation and xenograft recurrence. Cancer Res 70: 6870-6879.
    • (2010) Cancer Res , vol.70 , pp. 6870-6879
    • Gilbert, C.A.1    Daou, M.C.2    Moser, R.P.3    Ross, A.H.4
  • 8
    • 75349105363 scopus 로고    scopus 로고
    • NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
    • Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, et al. (2010) NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells 28: 5-16.
    • (2010) Stem Cells , vol.28 , pp. 5-16
    • Fan, X.1    Khaki, L.2    Zhu, T.S.3    Soules, M.E.4    Talsma, C.E.5
  • 9
    • 80052795862 scopus 로고    scopus 로고
    • Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
    • Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, et al. (2011) Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res 71: 6061-6072.
    • (2011) Cancer Res , vol.71 , pp. 6061-6072
    • Zhu, T.S.1    Costello, M.A.2    Talsma, C.E.3    Flack, C.G.4    Crowley, J.G.5
  • 10
    • 39349085391 scopus 로고    scopus 로고
    • Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors
    • Boulay JL, Miserez AR, Zweifel C, Sivasankaran B, Kana V, et al. (2007) Loss of NOTCH2 positively predicts survival in subgroups of human glial brain tumors. PLoS One 2: e576.
    • (2007) PLoS One , vol.2
    • Boulay, J.L.1    Miserez, A.R.2    Zweifel, C.3    Sivasankaran, B.4    Kana, V.5
  • 11
    • 27944477776 scopus 로고    scopus 로고
    • The extracellular space and matrix of gliomas
    • Zamecnik J, (2005) The extracellular space and matrix of gliomas. Acta Neuropathol 110: 435-442.
    • (2005) Acta Neuropathol , vol.110 , pp. 435-442
    • Zamecnik, J.1
  • 12
    • 58349102939 scopus 로고    scopus 로고
    • Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas
    • Sivasankaran B, Degen M, Ghaffari A, Hegi ME, Hamou MF, et al. (2009) Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas. Cancer Res 69: 458-465.
    • (2009) Cancer Res , vol.69 , pp. 458-465
    • Sivasankaran, B.1    Degen, M.2    Ghaffari, A.3    Hegi, M.E.4    Hamou, M.F.5
  • 13
    • 63749125730 scopus 로고    scopus 로고
    • Translating biology into clinic: the case of glioblastoma
    • Lino M, Merlo A, (2009) Translating biology into clinic: the case of glioblastoma. Curr Opin Cell Biol 21: 311-316.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 311-316
    • Lino, M.1    Merlo, A.2
  • 14
    • 0029047609 scopus 로고
    • Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
    • Matsuno K, Diederich RJ, Go MJ, Blaumueller CM, Artavanis-Tsakonas S, (1995) Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development 121: 2633-2644.
    • (1995) Development , vol.121 , pp. 2633-2644
    • Matsuno, K.1    Diederich, R.J.2    Go, M.J.3    Blaumueller, C.M.4    Artavanis-Tsakonas, S.5
  • 16
    • 13444292166 scopus 로고    scopus 로고
    • Deltex regulates T-cell activation by targeted degradation of active MEKK1
    • Liu WH, Lai MZ, (2005) Deltex regulates T-cell activation by targeted degradation of active MEKK1. Mol Cell Biol 25: 1367-1378.
    • (2005) Mol Cell Biol , vol.25 , pp. 1367-1378
    • Liu, W.H.1    Lai, M.Z.2
  • 17
    • 10744233414 scopus 로고    scopus 로고
    • F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation
    • Hu QD, Ang BT, Karsak M, Hu WP, Cui XY, et al. (2003) F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell 115: 163-175.
    • (2003) Cell , vol.115 , pp. 163-175
    • Hu, Q.D.1    Ang, B.T.2    Karsak, M.3    Hu, W.P.4    Cui, X.Y.5
  • 18
    • 10344235191 scopus 로고    scopus 로고
    • Axoglial interaction via the notch receptor in oligodendrocyte differentiation
    • Hu QD, Cui XY, Ng YK, Xiao ZC, (2004) Axoglial interaction via the notch receptor in oligodendrocyte differentiation. Ann Acad Med Singapore 33: 581-588.
    • (2004) Ann Acad Med Singapore , vol.33 , pp. 581-588
    • Hu, Q.D.1    Cui, X.Y.2    Ng, Y.K.3    Xiao, Z.C.4
  • 19
    • 24944472303 scopus 로고    scopus 로고
    • DNER acts as a neuron-specific Notch ligand during Bergmann glial development
    • Eiraku M, Tohgo A, Ono K, Kaneko M, Fujishima K, et al. (2005) DNER acts as a neuron-specific Notch ligand during Bergmann glial development. Nat Neurosci 8: 873-880.
    • (2005) Nat Neurosci , vol.8 , pp. 873-880
    • Eiraku, M.1    Tohgo, A.2    Ono, K.3    Kaneko, M.4    Fujishima, K.5
  • 20
    • 68049121594 scopus 로고    scopus 로고
    • DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation
    • Sun P, Xia S, Lal B, Eberhart CG, Quinones-Hinojosa A, et al. (2009) DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation. Stem Cells 27: 1473-1486.
    • (2009) Stem Cells , vol.27 , pp. 1473-1486
    • Sun, P.1    Xia, S.2    Lal, B.3    Eberhart, C.G.4    Quinones-Hinojosa, A.5
  • 21
    • 0036013773 scopus 로고    scopus 로고
    • Notching up another pathway
    • Brennan K, Gardner P, (2002) Notching up another pathway. Bioessays 24: 405-410.
    • (2002) Bioessays , vol.24 , pp. 405-410
    • Brennan, K.1    Gardner, P.2
  • 22
    • 0036778127 scopus 로고    scopus 로고
    • CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?
    • Martinez Arias A, Zecchini V, Brennan K, (2002) CSL-independent Notch signalling: a checkpoint in cell fate decisions during development? Curr Opin Genet Dev 12: 524-533.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 524-533
    • Martinez Arias, A.1    Zecchini, V.2    Brennan, K.3
  • 23
  • 24
    • 0035977003 scopus 로고    scopus 로고
    • Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor
    • Yamamoto N, Yamamoto S, Inagaki F, Kawaichi M, Fukamizu A, et al. (2001) Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor. J Biol Chem 276: 45031-45040.
    • (2001) J Biol Chem , vol.276 , pp. 45031-45040
    • Yamamoto, N.1    Yamamoto, S.2    Inagaki, F.3    Kawaichi, M.4    Fukamizu, A.5
  • 25
    • 0035856467 scopus 로고    scopus 로고
    • Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate
    • Ramain P, Khechumian K, Seugnet L, Arbogast N, Ackermann C, et al. (2001) Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate. Curr Biol 11: 1729-1738.
    • (2001) Curr Biol , vol.11 , pp. 1729-1738
    • Ramain, P.1    Khechumian, K.2    Seugnet, L.3    Arbogast, N.4    Ackermann, C.5
  • 26
    • 0032977124 scopus 로고    scopus 로고
    • Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines
    • Ishii N, Maier D, Merlo A, Tada M, Sawamura Y, et al. (1999) Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines. Brain Pathol 9: 469-479.
    • (1999) Brain Pathol , vol.9 , pp. 469-479
    • Ishii, N.1    Maier, D.2    Merlo, A.3    Tada, M.4    Sawamura, Y.5
  • 27
    • 0028888764 scopus 로고
    • Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas
    • Huettner C, Paulus W, Roggendorf W, (1995) Messenger RNA expression of the immunosuppressive cytokine IL-10 in human gliomas. Am J Pathol 146: 317-322.
    • (1995) Am J Pathol , vol.146 , pp. 317-322
    • Huettner, C.1    Paulus, W.2    Roggendorf, W.3
  • 28
    • 21144447742 scopus 로고    scopus 로고
    • Napthalimidobenzamide DB-51630: a novel DNA binding agent inducing p300 gene expression and exerting a potent anti-cancer activity
    • Suzuki K, Nagasawa H, Uto Y, Sugimoto Y, Noguchi K, et al. (2005) Napthalimidobenzamide DB-51630: a novel DNA binding agent inducing p300 gene expression and exerting a potent anti-cancer activity. Bioorg Med Chem 13: 4014-4021.
    • (2005) Bioorg Med Chem , vol.13 , pp. 4014-4021
    • Suzuki, K.1    Nagasawa, H.2    Uto, Y.3    Sugimoto, Y.4    Noguchi, K.5
  • 30
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, et al. (2004) Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 5: R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3    Bolstad, B.4    Dettling, M.5
  • 31
    • 12344330424 scopus 로고    scopus 로고
    • limmaGUI: a graphical user interface for linear modeling of microarray data
    • Wettenhall JM, Smyth GK, (2004) limmaGUI: a graphical user interface for linear modeling of microarray data. Bioinformatics 20: 3705-3706.
    • (2004) Bioinformatics , vol.20 , pp. 3705-3706
    • Wettenhall, J.M.1    Smyth, G.K.2
  • 32
    • 33745612095 scopus 로고    scopus 로고
    • Pvclust: an R package for assessing the uncertainty in hierarchical clustering
    • Suzuki R, Shimodaira H, (2006) Pvclust: an R package for assessing the uncertainty in hierarchical clustering. Bioinformatics 22: 1540-1542.
    • (2006) Bioinformatics , vol.22 , pp. 1540-1542
    • Suzuki, R.1    Shimodaira, H.2
  • 33
    • 0034020459 scopus 로고    scopus 로고
    • Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
    • Holland EC, Celestino J, Dai C, Schaefer L, Sawaya RE, et al. (2000) Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice. Nature Genetics 25: 55-57.
    • (2000) Nature Genetics , vol.25 , pp. 55-57
    • Holland, E.C.1    Celestino, J.2    Dai, C.3    Schaefer, L.4    Sawaya, R.E.5
  • 34
    • 75349095750 scopus 로고    scopus 로고
    • Deregulated signalling networks in human brain tumours
    • Grzmil M, Hemmings BA, (2010) Deregulated signalling networks in human brain tumours. Biochim Biophys Acta 1804: 476-483.
    • (2010) Biochim Biophys Acta , vol.1804 , pp. 476-483
    • Grzmil, M.1    Hemmings, B.A.2
  • 36
    • 54249136806 scopus 로고    scopus 로고
    • MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
    • Papagiannakopoulos T, Shapiro A, Kosik KS, (2008) MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res 68: 8164-8172.
    • (2008) Cancer Res , vol.68 , pp. 8164-8172
    • Papagiannakopoulos, T.1    Shapiro, A.2    Kosik, K.S.3
  • 37
    • 1342288971 scopus 로고    scopus 로고
    • Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice
    • Rangarajan A, Weinberg RA, (2003) Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice. Nat Rev Cancer 3: 952-959.
    • (2003) Nat Rev Cancer , vol.3 , pp. 952-959
    • Rangarajan, A.1    Weinberg, R.A.2
  • 38
    • 0242467470 scopus 로고    scopus 로고
    • Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis
    • Joy AM, Beaudry CE, Tran NL, Ponce FA, Holz DR, et al. (2003) Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis. J Cell Sci 116: 4409-4417.
    • (2003) J Cell Sci , vol.116 , pp. 4409-4417
    • Joy, A.M.1    Beaudry, C.E.2    Tran, N.L.3    Ponce, F.A.4    Holz, D.R.5
  • 39
    • 67650065524 scopus 로고    scopus 로고
    • Reduction of Akt2 inhibits migration and invasion of glioma cells
    • Zhang B, Gu F, She C, Guo H, Li W, et al. (2009) Reduction of Akt2 inhibits migration and invasion of glioma cells. Int J Cancer 125: 585-595.
    • (2009) Int J Cancer , vol.125 , pp. 585-595
    • Zhang, B.1    Gu, F.2    She, C.3    Guo, H.4    Li, W.5
  • 40
    • 64249143248 scopus 로고    scopus 로고
    • Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway
    • Strippoli R, Benedicto I, Perez Lozano ML, Cerezo A, Lopez-Cabrera M, et al. (2008) Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-kappaB/Snail1 pathway. Dis Model Mech 1: 264-274.
    • (2008) Dis Model Mech , vol.1 , pp. 264-274
    • Strippoli, R.1    Benedicto, I.2    Perez Lozano, M.L.3    Cerezo, A.4    Lopez-Cabrera, M.5
  • 41
    • 50249173450 scopus 로고    scopus 로고
    • MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
    • Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, et al. (2008) MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol Cell Biol 28: 5369-5380.
    • (2008) Mol Cell Biol , vol.28 , pp. 5369-5380
    • Gabriely, G.1    Wurdinger, T.2    Kesari, S.3    Esau, C.C.4    Burchard, J.5
  • 42
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, et al. (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347: 1999-2009.
    • (2002) N Engl J Med , vol.347 , pp. 1999-2009
    • van de Vijver, M.J.1    He, Y.D.2    van't Veer, L.J.3    Dai, H.4    Hart, A.A.5
  • 43
  • 44
    • 77952668917 scopus 로고    scopus 로고
    • Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness
    • Zhang P, Yang Y, Nolo R, Zweidler-McKay PA, Hughes DP, (2010) Regulation of NOTCH signaling by reciprocal inhibition of HES1 and Deltex 1 and its role in osteosarcoma invasiveness. Oncogene 29: 2916-2926.
    • (2010) Oncogene , vol.29 , pp. 2916-2926
    • Zhang, P.1    Yang, Y.2    Nolo, R.3    Zweidler-McKay, P.A.4    Hughes, D.P.5
  • 45
    • 7544226214 scopus 로고    scopus 로고
    • Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis
    • Oishi K, Kamakura S, Isazawa Y, Yoshimatsu T, Kuida K, et al. (2004) Notch promotes survival of neural precursor cells via mechanisms distinct from those regulating neurogenesis. Dev Biol 276: 172-184.
    • (2004) Dev Biol , vol.276 , pp. 172-184
    • Oishi, K.1    Kamakura, S.2    Isazawa, Y.3    Yoshimatsu, T.4    Kuida, K.5
  • 46
    • 61449123217 scopus 로고    scopus 로고
    • Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation
    • Zohrabian VM, Forzani B, Chau Z, Murali R, Jhanwar-Uniyal M, (2009) Rho/ROCK and MAPK signaling pathways are involved in glioblastoma cell migration and proliferation. Anticancer Res 29: 119-123.
    • (2009) Anticancer Res , vol.29 , pp. 119-123
    • Zohrabian, V.M.1    Forzani, B.2    Chau, Z.3    Murali, R.4    Jhanwar-Uniyal, M.5
  • 47
    • 0037103912 scopus 로고    scopus 로고
    • Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro
    • Lakka SS, Jasti SL, Gondi C, Boyd D, Chandrasekar N, et al. (2002) Downregulation of MMP-9 in ERK-mutated stable transfectants inhibits glioma invasion in vitro. Oncogene 21: 5601-5608.
    • (2002) Oncogene , vol.21 , pp. 5601-5608
    • Lakka, S.S.1    Jasti, S.L.2    Gondi, C.3    Boyd, D.4    Chandrasekar, N.5
  • 49
    • 67650538055 scopus 로고    scopus 로고
    • Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion
    • Huang TH, Wu F, Loeb GB, Hsu R, Heidersbach A, et al. (2009) Up-regulation of miR-21 by HER2/neu signaling promotes cell invasion. J Biol Chem 284: 18515-18524.
    • (2009) J Biol Chem , vol.284 , pp. 18515-18524
    • Huang, T.H.1    Wu, F.2    Loeb, G.B.3    Hsu, R.4    Heidersbach, A.5
  • 50
    • 28144458897 scopus 로고    scopus 로고
    • LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans
    • Yoo AS, Greenwald I, (2005) LIN-12/Notch activation leads to microRNA-mediated down-regulation of Vav in C. elegans. Science 310: 1330-1333.
    • (2005) Science , vol.310 , pp. 1330-1333
    • Yoo, A.S.1    Greenwald, I.2
  • 51
    • 62149114138 scopus 로고    scopus 로고
    • Dual-specificity phosphatases: critical regulators with diverse cellular targets
    • Patterson KI, Brummer T, O'Brien PM, Daly RJ, (2009) Dual-specificity phosphatases: critical regulators with diverse cellular targets. Biochem J 418: 475-489.
    • (2009) Biochem J , vol.418 , pp. 475-489
    • Patterson, K.I.1    Brummer, T.2    O'Brien, P.M.3    Daly, R.J.4
  • 52
    • 0033517348 scopus 로고    scopus 로고
    • Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2
    • Mitsuuchi Y, Johnson SW, Sonoda G, Tanno S, Golemis EA, et al. (1999) Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2. Oncogene 18: 4891-4898.
    • (1999) Oncogene , vol.18 , pp. 4891-4898
    • Mitsuuchi, Y.1    Johnson, S.W.2    Sonoda, G.3    Tanno, S.4    Golemis, E.A.5
  • 53
    • 0031923281 scopus 로고    scopus 로고
    • Notch inhibition of E47 supports the existence of a novel signaling pathway
    • Ordentlich P, Lin A, Shen CP, Blaumueller C, Matsuno K, et al. (1998) Notch inhibition of E47 supports the existence of a novel signaling pathway. Mol Cell Biol 18: 2230-2239.
    • (1998) Mol Cell Biol , vol.18 , pp. 2230-2239
    • Ordentlich, P.1    Lin, A.2    Shen, C.P.3    Blaumueller, C.4    Matsuno, K.5
  • 54
    • 2942554826 scopus 로고    scopus 로고
    • NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes
    • Cui XY, Hu QD, Tekaya M, Shimoda Y, Ang BT, et al. (2004) NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes. J Biol Chem 279: 25858-25865.
    • (2004) J Biol Chem , vol.279 , pp. 25858-25865
    • Cui, X.Y.1    Hu, Q.D.2    Tekaya, M.3    Shimoda, Y.4    Ang, B.T.5
  • 55
    • 68249147994 scopus 로고    scopus 로고
    • Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy
    • Hsiao HW, Liu WH, Wang CJ, Lo YH, Wu YH, et al. (2009) Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy. Immunity 31: 72-83.
    • (2009) Immunity , vol.31 , pp. 72-83
    • Hsiao, H.W.1    Liu, W.H.2    Wang, C.J.3    Lo, Y.H.4    Wu, Y.H.5
  • 56
    • 0038132179 scopus 로고    scopus 로고
    • Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors
    • Oliver TG, Grasfeder LL, Carroll AL, Kaiser C, Gillingham CL, et al. (2003) Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors. Proc Natl Acad Sci U S A 100: 7331-7336.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7331-7336
    • Oliver, T.G.1    Grasfeder, L.L.2    Carroll, A.L.3    Kaiser, C.4    Gillingham, C.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.