Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis

Journal of Cell Science

Volumn 116, Issue 21, 2003, Pages 4409-4417

  Joy, Anna M ^a   Beaudry, Christian E ^a   Tran, Nhan L ^a   Ponce, Francisco A ^a   Holz, David R ^a   Demuth, Tim ^a   Berens, Michael E ^a  

^a The Transl Genomics Research Inst   (United States)

Author keywords

Akt; Chemotherapy; Glioma; Migration; PI3 K

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CAMPTOTHECIN; CYTOTOXIC AGENT; GLYCOGEN SYNTHASE KINASE 3; LAMININ; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; BASAL CELL; BRAIN TUMOR; CELL ACTIVATION; CELL MANIPULATION; CELL MIGRATION; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; CYTOTOXICITY; DISEASE PREDISPOSITION; DOSE RESPONSE; DOWNSTREAM PROCESSING; ENZYME SUBSTRATE; GLIOMA CELL; HUMAN; HUMAN CELL; MIGRATION INHIBITION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD29; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CAMPTOTHECIN; CELL MOVEMENT; CHROMONES; ENZYME ACTIVATION; ENZYME INHIBITORS; GLIOMA; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMIDAZOLES; IMMUNOHISTOCHEMISTRY; LAMININ; MEMBRANE GLYCOPROTEINS; MORPHOLINES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0242467470     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00712     Document Type: Article

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