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Volumn 11, Issue , 2011, Pages

STAT6 expression in glioblastoma promotes invasive growth

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 4; INTERSTITIAL COLLAGENASE; SHORT HAIRPIN RNA; STAT6 PROTEIN; THYMIDINE; TRITIUM; UROKINASE; EPIDERMAL GROWTH FACTOR; SMALL INTERFERING RNA; TYROSINE;

EID: 79956227340     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-11-184     Document Type: Article
Times cited : (40)

References (76)
  • 1
    • 79957617701 scopus 로고    scopus 로고
    • REMBRANDT home page
    • Accessed 2010 October 1st, National Cancer Institute
    • National Cancer Institute REMBRANDT home page. 2005, Accessed 2010 October 1st, National Cancer Institute., http://rembrandt.nci.nih.gov
    • (2005)
  • 3
    • 48649096955 scopus 로고    scopus 로고
    • Vaccination Elicits Correlated Immune and Clinical Responses in Glioblastoma Multiforme Patients
    • 10.1158/0008-5472.CAN-07-5973, 18632651
    • Wheeler CJ, Black KL, Liu G, Mazer M, Zhang X, Pepkowitz S, Goldfinger D, Ng H, Irvin D, Yu JS. Vaccination Elicits Correlated Immune and Clinical Responses in Glioblastoma Multiforme Patients. Cancer Research 2008, 68:5955-5964. 10.1158/0008-5472.CAN-07-5973, 18632651.
    • (2008) Cancer Research , vol.68 , pp. 5955-5964
    • Wheeler, C.J.1    Black, K.L.2    Liu, G.3    Mazer, M.4    Zhang, X.5    Pepkowitz, S.6    Goldfinger, D.7    Ng, H.8    Irvin, D.9    Yu, J.S.10
  • 4
    • 65749098835 scopus 로고    scopus 로고
    • Therapeutic targets in malignant glioblastoma microenvironment
    • 10.1016/j.semradonc.2009.02.004, 19464631
    • Barcellos-Hoff MH, Newcomb EW, Zagzag D, Narayana A. Therapeutic targets in malignant glioblastoma microenvironment. Semin.Radiat.Oncol 2009, 19:163-170. 10.1016/j.semradonc.2009.02.004, 19464631.
    • (2009) Semin.Radiat.Oncol , vol.19 , pp. 163-170
    • Barcellos-Hoff, M.H.1    Newcomb, E.W.2    Zagzag, D.3    Narayana, A.4
  • 5
    • 32944479646 scopus 로고    scopus 로고
    • Therapeutic Advances in the Treatment of Glioblastoma: Rationale and Potential Role of Targeted Agents
    • 10.1634/theoncologist.11-2-152, 16476836
    • Reardon DA, Wen PY. Therapeutic Advances in the Treatment of Glioblastoma: Rationale and Potential Role of Targeted Agents. The Oncologist 2006, 11:152-164. 10.1634/theoncologist.11-2-152, 16476836.
    • (2006) The Oncologist , vol.11 , pp. 152-164
    • Reardon, D.A.1    Wen, P.Y.2
  • 8
    • 28544438023 scopus 로고    scopus 로고
    • Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
    • 10.1158/1078-0432.CCR-05-0827, 16322287
    • Haura EB, Zheng Z, Song L, Cantor A, Bepler G. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin.Cancer Res 2005, 11:8288-8294. 10.1158/1078-0432.CCR-05-0827, 16322287.
    • (2005) Clin.Cancer Res , vol.11 , pp. 8288-8294
    • Haura, E.B.1    Zheng, Z.2    Song, L.3    Cantor, A.4    Bepler, G.5
  • 9
    • 0034658698 scopus 로고    scopus 로고
    • STATs in oncogenesis
    • 10.1038/sj.onc.1203527, 10851046
    • Bowman T, Garcia R, Turkson J, Jove R. STATs in oncogenesis. Oncogene 2000, 19:2474-2488. 10.1038/sj.onc.1203527, 10851046.
    • (2000) Oncogene , vol.19 , pp. 2474-2488
    • Bowman, T.1    Garcia, R.2    Turkson, J.3    Jove, R.4
  • 10
    • 7444266895 scopus 로고    scopus 로고
    • Head and neck cancer: meeting summary and research opportunities
    • 10.1158/0008-5472.CAN-04-2445, 15520225
    • Grandis JR, Pietenpol JA, Greenberger JS, Pelroy RA, Mohla S. Head and neck cancer: meeting summary and research opportunities. Cancer Res 2004, 64:8126-8129. 10.1158/0008-5472.CAN-04-2445, 15520225.
    • (2004) Cancer Res , vol.64 , pp. 8126-8129
    • Grandis, J.R.1    Pietenpol, J.A.2    Greenberger, J.S.3    Pelroy, R.A.4    Mohla, S.5
  • 11
    • 0036554816 scopus 로고    scopus 로고
    • Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention
    • Buettner R, Mora LB, Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention. Clin.Cancer Res 2002, 8:945-954.
    • (2002) Clin.Cancer Res , vol.8 , pp. 945-954
    • Buettner, R.1    Mora, L.B.2    Jove, R.3
  • 12
    • 44949130806 scopus 로고    scopus 로고
    • Signaling molecules: the pathogenic role of the IL-6/STAT-3 trans signaling pathway in intestinal inflammation and in colonic cancer
    • 10.2174/138945008784221116, 18473764
    • Atreya R, Neurath MF. Signaling molecules: the pathogenic role of the IL-6/STAT-3 trans signaling pathway in intestinal inflammation and in colonic cancer. Curr Drug Targets 2008, 9:369-74. 10.2174/138945008784221116, 18473764.
    • (2008) Curr Drug Targets , vol.9 , pp. 369-374
    • Atreya, R.1    Neurath, M.F.2
  • 15
    • 0029834676 scopus 로고    scopus 로고
    • Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome
    • 10.1073/pnas.93.17.9148, 38610, 8799169
    • Zhang Q, Nowak I, Vonderheid EC, Rook AH, Kadin ME, Nowell PC. Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome. Proc Natl Acad Sci 1996, 93:9148-9153. 10.1073/pnas.93.17.9148, 38610, 8799169.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 9148-9153
    • Zhang, Q.1    Nowak, I.2    Vonderheid, E.C.3    Rook, A.H.4    Kadin, M.E.5    Nowell, P.C.6
  • 16
    • 85047699589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2)
    • Schaefer LK, Ren Z, Fuller GN, Schaefer TS. Constitutive activation of Stat3alpha in brain tumors: localization to tumor endothelial cells and activation by the endothelial tyrosine kinase receptor (VEGFR-2). Oncogene 2002, 27:2058-65.
    • (2002) Oncogene , vol.27 , pp. 2058-2065
    • Schaefer, L.K.1    Ren, Z.2    Fuller, G.N.3    Schaefer, T.S.4
  • 17
    • 1842471336 scopus 로고    scopus 로고
    • Signaling through the epidermal growth factor receptor during the development of malignancy
    • 10.1016/j.pharmthera.2004.01.002, 15056497
    • Grandis JR, Sok JC. Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 2004, 102:37-46. 10.1016/j.pharmthera.2004.01.002, 15056497.
    • (2004) Pharmacol Ther , vol.102 , pp. 37-46
    • Grandis, J.R.1    Sok, J.C.2
  • 18
    • 3042748279 scopus 로고    scopus 로고
    • Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells
    • 10.1186/1471-2407-3-23, 212316, 13678425
    • Konnikova L, Kotecki M, Kruger MM, Cochran BH. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. BMC Cancer 2003, 3:23. 10.1186/1471-2407-3-23, 212316, 13678425.
    • (2003) BMC Cancer , vol.3 , pp. 23
    • Konnikova, L.1    Kotecki, M.2    Kruger, M.M.3    Cochran, B.H.4
  • 19
    • 56649112857 scopus 로고    scopus 로고
    • Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells
    • 10.1016/j.canlet.2008.08.011, 18793823
    • Liang QC, Xiong H, Zhao ZW, Jia D, Li WX, Qin HZ, Deng JP, Gao L, Zhang H, Gao GD. Inhibition of transcription factor STAT5b suppresses proliferation, induces G1 cell cycle arrest and reduces tumor cell invasion in human glioblastoma multiforme cells. Cancer Letters 2009, 273:164-171. 10.1016/j.canlet.2008.08.011, 18793823.
    • (2009) Cancer Letters , vol.273 , pp. 164-171
    • Liang, Q.C.1    Xiong, H.2    Zhao, Z.W.3    Jia, D.4    Li, W.X.5    Qin, H.Z.6    Deng, J.P.7    Gao, L.8    Zhang, H.9    Gao, G.D.10
  • 20
    • 0030447148 scopus 로고    scopus 로고
    • In vitro activation of Stat3 by epidermal growth factor receptor kinase
    • 10.1073/pnas.93.24.13704, 19397, 8942998
    • Park OK, Schaefer TS, Nathans D. In vitro activation of Stat3 by epidermal growth factor receptor kinase. Proc Natl Acad Sci 1996, 93:13704-8. 10.1073/pnas.93.24.13704, 19397, 8942998.
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 13704-13708
    • Park, O.K.1    Schaefer, T.S.2    Nathans, D.3
  • 21
    • 0032869581 scopus 로고    scopus 로고
    • Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins
    • 10.1007/s000180050393, 10526571
    • Decker T, Kovarik P. Transcription factor activity of STAT proteins: structural requirements and regulation by phosphorylation and interacting proteins. Cellular and Molecular Life Sciences 1999, 55:1535-1546. 10.1007/s000180050393, 10526571.
    • (1999) Cellular and Molecular Life Sciences , vol.55 , pp. 1535-1546
    • Decker, T.1    Kovarik, P.2
  • 22
    • 0032877019 scopus 로고    scopus 로고
    • The role of STATs in proliferation, differentiation, and apoptosis
    • 10.1007/s000180050394, 10526572
    • Mui A. The role of STATs in proliferation, differentiation, and apoptosis. Cellular and Molecular Life Sciences 1999, 55:1547-1558. 10.1007/s000180050394, 10526572.
    • (1999) Cellular and Molecular Life Sciences , vol.55 , pp. 1547-1558
    • Mui, A.1
  • 23
    • 0034352334 scopus 로고    scopus 로고
    • Regulation of Bcl-xL: a little bit of this and a little bit of STAT
    • 10.1097/00001622-200011000-00006, 11085453
    • Grad JM, Zeng XR, Boise LH. Regulation of Bcl-xL: a little bit of this and a little bit of STAT. Curr Opin Oncol 2000, 12:543-9. 10.1097/00001622-200011000-00006, 11085453.
    • (2000) Curr Opin Oncol , vol.12 , pp. 543-549
    • Grad, J.M.1    Zeng, X.R.2    Boise, L.H.3
  • 25
    • 0033848172 scopus 로고    scopus 로고
    • STAT5-Dependent CyclinD1 and Bcl-xL expression in Bcr-Abl-transformed cells
    • 10.1006/mcbr.2000.0231, 10964754
    • deGroot RP, Raaijmakers JA, Lammers JW, Koenderman L. STAT5-Dependent CyclinD1 and Bcl-xL expression in Bcr-Abl-transformed cells. Mol Cell Biol Res Commun 2000, 3:299-305. 10.1006/mcbr.2000.0231, 10964754.
    • (2000) Mol Cell Biol Res Commun , vol.3 , pp. 299-305
    • deGroot, R.P.1    Raaijmakers, J.A.2    Lammers, J.W.3    Koenderman, L.4
  • 27
    • 0033521595 scopus 로고    scopus 로고
    • STAT3 is required for the gp130-mediated full activation of the c-myc gene
    • 10.1084/jem.189.1.63, 1887683, 9874564
    • Kiuchi N, Nakajima K, Ichiba M, Fukada T, Narimatsu M, Mizuno K, Hibi M, Hirano T. STAT3 is required for the gp130-mediated full activation of the c-myc gene. J exp Med 1999, 189:63-73. 10.1084/jem.189.1.63, 1887683, 9874564.
    • (1999) J exp Med , vol.189 , pp. 63-73
    • Kiuchi, N.1    Nakajima, K.2    Ichiba, M.3    Fukada, T.4    Narimatsu, M.5    Mizuno, K.6    Hibi, M.7    Hirano, T.8
  • 28
    • 0036128997 scopus 로고    scopus 로고
    • Selective activation of members of the signal transducers and activators of transcription family in prostate carcinoma
    • 10.1016/S0022-5347(05)65249-4, 11912448
    • Ni Z, Lou W, Lee SO, Dhir R, DeMiguel F, Grandis JR, Gao AC. Selective activation of members of the signal transducers and activators of transcription family in prostate carcinoma. J Urol 2002, 167:1859-1862. 10.1016/S0022-5347(05)65249-4, 11912448.
    • (2002) J Urol , vol.167 , pp. 1859-1862
    • Ni, Z.1    Lou, W.2    Lee, S.O.3    Dhir, R.4    DeMiguel, F.5    Grandis, J.R.6    Gao, A.C.7
  • 30
    • 0038820386 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription proteins in leukemias
    • 10.1182/blood-2002-04-1204, 12480704
    • Benekli M, Baer MR, Baumann H, Wetzler M. Signal transducer and activator of transcription proteins in leukemias. Blood 2003, 101:2940-2954. 10.1182/blood-2002-04-1204, 12480704.
    • (2003) Blood , vol.101 , pp. 2940-2954
    • Benekli, M.1    Baer, M.R.2    Baumann, H.3    Wetzler, M.4
  • 31
    • 0037079728 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma
    • 10.1182/blood.V99.2.618, 11781246
    • Skinnider BF, Elia AJ, Gascoyne RD, Patterson B, Trumper L, Kapp U, Mak TW. Signal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma. Blood 2002, 99:618-626. 10.1182/blood.V99.2.618, 11781246.
    • (2002) Blood , vol.99 , pp. 618-626
    • Skinnider, B.F.1    Elia, A.J.2    Gascoyne, R.D.3    Patterson, B.4    Trumper, L.5    Kapp, U.6    Mak, T.W.7
  • 33
    • 15244350510 scopus 로고    scopus 로고
    • Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line
    • 10.1182/blood-2004-09-3701, 15572583
    • Melzner I, Bucur AJ, Bruderlein S, Dorsch K, Hasel C, Barth TF, Leithauser F, Moller P. Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line. Blood 2005, 105:2535-2542. 10.1182/blood-2004-09-3701, 15572583.
    • (2005) Blood , vol.105 , pp. 2535-2542
    • Melzner, I.1    Bucur, A.J.2    Bruderlein, S.3    Dorsch, K.4    Hasel, C.5    Barth, T.F.6    Leithauser, F.7    Moller, P.8
  • 34
    • 32644434424 scopus 로고    scopus 로고
    • The role of constitutively active Stat6 in leukemia and lymphoma
    • 10.1016/j.critrevonc.2005.08.005, 16213149
    • Bruns HA, Kaplan MH. The role of constitutively active Stat6 in leukemia and lymphoma. Critical Reviews in Oncology/Hematology 2006, 57:245-253. 10.1016/j.critrevonc.2005.08.005, 16213149.
    • (2006) Critical Reviews in Oncology/Hematology , vol.57 , pp. 245-253
    • Bruns, H.A.1    Kaplan, M.H.2
  • 36
    • 0034698032 scopus 로고    scopus 로고
    • Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells
    • 10.1074/jbc.M003203200, 10806212
    • Hussaini IM, Karns LR, Vinton G, Carpenter JE, Redpath GT, Sando JJ. Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells. J.Biol.Chem 2000, 275:22348-22354. 10.1074/jbc.M003203200, 10806212.
    • (2000) J.Biol.Chem , vol.275 , pp. 22348-22354
    • Hussaini, I.M.1    Karns, L.R.2    Vinton, G.3    Carpenter, J.E.4    Redpath, G.T.5    Sando, J.J.6
  • 37
    • 35948976100 scopus 로고    scopus 로고
    • Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion
    • 10.1158/0008-5472.CAN-07-0030, 2386949, 17974965
    • Amos S, Mut M, diPierro CG, Carpenter JE, Xiao A, Kohutek ZA, Redpath GT, Zhao Y, Wang J, Shaffrey ME, Hussaini IM. Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion. Cancer Research 2007, 67:10241-10251. 10.1158/0008-5472.CAN-07-0030, 2386949, 17974965.
    • (2007) Cancer Research , vol.67 , pp. 10241-10251
    • Amos, S.1    Mut, M.2    diPierro, C.G.3    Carpenter, J.E.4    Xiao, A.5    Kohutek, Z.A.6    Redpath, G.T.7    Zhao, Y.8    Wang, J.9    Shaffrey, M.E.10    Hussaini, I.M.11
  • 38
    • 0142039051 scopus 로고    scopus 로고
    • Identification of Naf1/ABIN-1 among TNF-alpha-induced expressed genes in human synoviocytes using oligonucleaotide microarrays
    • 10.1016/S0014-5793(03)00823-8, 12965196
    • Gallagher J, Howlin J, McCarthy C, Murphy EP, Bresnihan B, FitzGerald O, Godson C, Brady HR, Martin F. Identification of Naf1/ABIN-1 among TNF-alpha-induced expressed genes in human synoviocytes using oligonucleaotide microarrays. FEBS Lett 2003, 551:8-12. 10.1016/S0014-5793(03)00823-8, 12965196.
    • (2003) FEBS Lett , vol.551 , pp. 8-12
    • Gallagher, J.1    Howlin, J.2    McCarthy, C.3    Murphy, E.P.4    Bresnihan, B.5    FitzGerald, O.6    Godson, C.7    Brady, H.R.8    Martin, F.9
  • 39
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
    • Li C, Wong WH. Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection. Proc Natl Acad Sci 2001,
    • (2001) Proc Natl Acad Sci
    • Li, C.1    Wong, W.H.2
  • 40
    • 51049123447 scopus 로고    scopus 로고
    • Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas
    • 10.1158/1541-7786.MCR-07-2180, 18505913
    • Brantley EC, Benveniste EN. Signal Transducer and Activator of Transcription-3: A Molecular Hub for Signaling Pathways in Gliomas. Mol Cancer Res 2008, 6:675-684. 10.1158/1541-7786.MCR-07-2180, 18505913.
    • (2008) Mol Cancer Res , vol.6 , pp. 675-684
    • Brantley, E.C.1    Benveniste, E.N.2
  • 42
    • 46949092766 scopus 로고    scopus 로고
    • Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells
    • 10.1007/s11060-008-9590-9, 18415045
    • Gu J, Li G, Sun T, Su Y, Zhang X, Shen J, Tian Z, Zhang J. Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells. J Neurooncol 2008, 89:9-17. 10.1007/s11060-008-9590-9, 18415045.
    • (2008) J Neurooncol , vol.89 , pp. 9-17
    • Gu, J.1    Li, G.2    Sun, T.3    Su, Y.4    Zhang, X.5    Shen, J.6    Tian, Z.7    Zhang, J.8
  • 43
    • 35448979864 scopus 로고    scopus 로고
    • A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients
    • 10.1158/0008-5472.CAN-07-1243, 17942891
    • Hussain SF, Kong LY, Jordan J, Conrad C, Madden T, Fokt I, Priebe W, Heimberger AB. A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. Cancer Research 2007, 67:9630-9636. 10.1158/0008-5472.CAN-07-1243, 17942891.
    • (2007) Cancer Research , vol.67 , pp. 9630-9636
    • Hussain, S.F.1    Kong, L.Y.2    Jordan, J.3    Conrad, C.4    Madden, T.5    Fokt, I.6    Priebe, W.7    Heimberger, A.B.8
  • 44
    • 0036168305 scopus 로고    scopus 로고
    • IL-13Rα2, a Decoy Receptor for IL-13 Acts As an Inhibitor of IL-4-dependent Signal Transduction in Glioblastoma Cells
    • Rahaman SO, Sharma P, Harbor PC, Aman MJ, Vogelbaum MA, Haque SJ. IL-13Rα2, a Decoy Receptor for IL-13 Acts As an Inhibitor of IL-4-dependent Signal Transduction in Glioblastoma Cells. Cancer Research 2002, 62:1103-1109.
    • (2002) Cancer Research , vol.62 , pp. 1103-1109
    • Rahaman, S.O.1    Sharma, P.2    Harbor, P.C.3    Aman, M.J.4    Vogelbaum, M.A.5    Haque, S.J.6
  • 45
    • 0030840464 scopus 로고    scopus 로고
    • STATs and Gene Regulation
    • 10.1126/science.277.5332.1630, 9287210
    • Darnell JE. STATs and Gene Regulation. Science 1997, 277:1630-1635. 10.1126/science.277.5332.1630, 9287210.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell, J.E.1
  • 46
    • 34548140134 scopus 로고    scopus 로고
    • How cells respond to interferons revisited: From early history to current complexity
    • 10.1016/j.cytogfr.2007.06.013, 2081984, 17683974
    • Stark GR. How cells respond to interferons revisited: From early history to current complexity. Cytokine Growth Factor Rev 2007, 18:419-423. 10.1016/j.cytogfr.2007.06.013, 2081984, 17683974.
    • (2007) Cytokine Growth Factor Rev , vol.18 , pp. 419-423
    • Stark, G.R.1
  • 47
    • 0032996486 scopus 로고    scopus 로고
    • The Jak-Stat pathway: cytokine signaling from the receptor to the nucleus
    • 10.3109/10799899909036638, 10071751
    • Heim MH. The Jak-Stat pathway: cytokine signaling from the receptor to the nucleus. J Recept Signal Transduct Res 1999, 19:75-120. 10.3109/10799899909036638, 10071751.
    • (1999) J Recept Signal Transduct Res , vol.19 , pp. 75-120
    • Heim, M.H.1
  • 48
    • 0031805248 scopus 로고    scopus 로고
    • JAK/STAT signaling by cytokine receptors
    • 10.1016/S0952-7915(98)80165-9, 9638363
    • Liu KD, Gaffen SL, Goldsmith MA. JAK/STAT signaling by cytokine receptors. Current Opinion in Immunology 1998, 10:271-278. 10.1016/S0952-7915(98)80165-9, 9638363.
    • (1998) Current Opinion in Immunology , vol.10 , pp. 271-278
    • Liu, K.D.1    Gaffen, S.L.2    Goldsmith, M.A.3
  • 49
    • 0035313701 scopus 로고    scopus 로고
    • The Stat family in cytokine signaling
    • 10.1016/S0955-0674(00)00199-X, 11248555
    • Ihle JM. The Stat family in cytokine signaling. Current Opinion in Cell Biology 2001, 13:211-217. 10.1016/S0955-0674(00)00199-X, 11248555.
    • (2001) Current Opinion in Cell Biology , vol.13 , pp. 211-217
    • Ihle, J.M.1
  • 50
    • 69449106110 scopus 로고    scopus 로고
    • IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
    • 10.1073/pnas.0906988106, 2726336, 19666510
    • Guo L, Wei G, Zhu J, Liao W, Leonard WJ, Zhao K, Paul W. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. PNAS 2009, 106:13463-13468. 10.1073/pnas.0906988106, 2726336, 19666510.
    • (2009) PNAS , vol.106 , pp. 13463-13468
    • Guo, L.1    Wei, G.2    Zhu, J.3    Liao, W.4    Leonard, W.J.5    Zhao, K.6    Paul, W.7
  • 51
    • 0031953831 scopus 로고    scopus 로고
    • Stat3 activation by Src induces specific gene regulation and is required for cell transformation
    • 110634, 9566874
    • Turkson J, Bowman T, Garcia R, Caldenhoven E, De Groot RP, Jove R. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol 1998, 18:2545-52. 110634, 9566874.
    • (1998) Mol Cell Biol , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 52
    • 85047691138 scopus 로고    scopus 로고
    • Stat3 is required for the development of skin cancer
    • 514594, 15343379
    • Pedranzini L, Leitch A, Bromberg J. Stat3 is required for the development of skin cancer. J Clin Invest 2004, 114:619-22. 514594, 15343379.
    • (2004) J Clin Invest , vol.114 , pp. 619-622
    • Pedranzini, L.1    Leitch, A.2    Bromberg, J.3
  • 53
    • 70350541138 scopus 로고    scopus 로고
    • STAT3 as a central regulator of tumor metastases
    • 10.2174/156652409788488720, 19601811
    • Devarajan E, Huang S. STAT3 as a central regulator of tumor metastases. Curr Mol Med 2009, 9:626-33. 10.2174/156652409788488720, 19601811.
    • (2009) Curr Mol Med , vol.9 , pp. 626-633
    • Devarajan, E.1    Huang, S.2
  • 54
    • 47949122939 scopus 로고    scopus 로고
    • Transcriptional control of the melanoma malignant phenotype
    • 10.4161/cbt.7.7.6535, 18698165
    • Melnikova VO, Bar-Eli M. Transcriptional control of the melanoma malignant phenotype. Cancer Biol Ther 2008, 7:997-1003. 10.4161/cbt.7.7.6535, 18698165.
    • (2008) Cancer Biol Ther , vol.7 , pp. 997-1003
    • Melnikova, V.O.1    Bar-Eli, M.2
  • 55
    • 40449135440 scopus 로고    scopus 로고
    • Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression
    • 10.1007/s10911-008-9062-z, 18228120
    • Wagner KU, Rui H. Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression. J Mammary Gland Biol Neoplasia 2008, 13:93-103. 10.1007/s10911-008-9062-z, 18228120.
    • (2008) J Mammary Gland Biol Neoplasia , vol.13 , pp. 93-103
    • Wagner, K.U.1    Rui, H.2
  • 56
    • 45849116295 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 5A/B in prostate and breast cancers
    • 10.1677/ERC-08-0013, 18508994
    • Tan SH, Nevalainen MT. Signal transducer and activator of transcription 5A/B in prostate and breast cancers. Endocr Relat Cancer 2008, 15:367-90. 10.1677/ERC-08-0013, 18508994.
    • (2008) Endocr Relat Cancer , vol.15 , pp. 367-390
    • Tan, S.H.1    Nevalainen, M.T.2
  • 59
    • 0032932830 scopus 로고    scopus 로고
    • Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression
    • 84225, 10207105
    • Soon L, Flechner L, Gutkind JS, Wang LH, Baserga R, Pierce JH, Li W. Insulin-like growth factor I synergizes with interleukin 4 for hematopoietic cell proliferation independent of insulin receptor substrate expression. Mol Cell Biol 1999, 19:3816-28. 84225, 10207105.
    • (1999) Mol Cell Biol , vol.19 , pp. 3816-3828
    • Soon, L.1    Flechner, L.2    Gutkind, J.S.3    Wang, L.H.4    Baserga, R.5    Pierce, J.H.6    Li, W.7
  • 60
    • 0033518113 scopus 로고    scopus 로고
    • Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblasts
    • 10.1038/sj.onc.1203148, 10602484
    • Kriebel P, Patel BK, Nelson SA, Grusby MJ, LaRochelle WJ. Consequences of Stat6 deletion on Sis/PDGF- and IL-4-induced proliferation and transcriptional activation in murine fibroblasts. Oncogene 1999, 18:7294-302. 10.1038/sj.onc.1203148, 10602484.
    • (1999) Oncogene , vol.18 , pp. 7294-7302
    • Kriebel, P.1    Patel, B.K.2    Nelson, S.A.3    Grusby, M.J.4    LaRochelle, W.J.5
  • 62
    • 35148822215 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription -6 (STAT6) is a constitutively expressed survival factor in human prostate cancer
    • 10.1002/pros.20640, 17705178
    • Das S, Roth CP, Wasson LM, Vishwanatha JK. Signal transducer and activator of transcription -6 (STAT6) is a constitutively expressed survival factor in human prostate cancer. Prostate 2007, 67:1550-64. 10.1002/pros.20640, 17705178.
    • (2007) Prostate , vol.67 , pp. 1550-1564
    • Das, S.1    Roth, C.P.2    Wasson, L.M.3    Vishwanatha, J.K.4
  • 63
    • 79251601170 scopus 로고    scopus 로고
    • MMP-1-PAR1 axis mediates LPA-induced epithelial ovarian cancer (EOC) invasion
    • 10.1016/j.ygyno.2010.10.032, 21093894
    • Wang FQ, Fisher J, Fishman DA. MMP-1-PAR1 axis mediates LPA-induced epithelial ovarian cancer (EOC) invasion. Gynecol Oncol 2011, 120:247-55. 10.1016/j.ygyno.2010.10.032, 21093894.
    • (2011) Gynecol Oncol , vol.120 , pp. 247-255
    • Wang, F.Q.1    Fisher, J.2    Fishman, D.A.3
  • 64
    • 77953136445 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediated regulation of urokinase plasminogen activator expression and glioblastoma invasion via C-SRC/MAPK/AP-1 signaling pathways
    • 10.1097/NEN.0b013e3181e008fe, 20467333
    • Amos S, Redpath GT, Dipierro CG, Carpenter JE, Hussaini IM. Epidermal growth factor receptor-mediated regulation of urokinase plasminogen activator expression and glioblastoma invasion via C-SRC/MAPK/AP-1 signaling pathways. J Neuropathol Exp Neurol 2010, 69:582-92. 10.1097/NEN.0b013e3181e008fe, 20467333.
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 582-592
    • Amos, S.1    Redpath, G.T.2    Dipierro, C.G.3    Carpenter, J.E.4    Hussaini, I.M.5
  • 65
    • 79959263572 scopus 로고    scopus 로고
    • Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells
    • Takahashi S, Yamada-Okabe H, Hamada K, Ohta S, Kawase T, Yoshida K, Toda M. Downregulation of uPARAP mediates cytoskeletal rearrangements and decreases invasion and migration properties in glioma cells. J Neurooncol 2010,
    • (2010) J Neurooncol
    • Takahashi, S.1    Yamada-Okabe, H.2    Hamada, K.3    Ohta, S.4    Kawase, T.5    Yoshida, K.6    Toda, M.7
  • 66
    • 17644387578 scopus 로고    scopus 로고
    • Matrix metalloproteinases target protease-activated receptors on the tumor cell surface
    • 10.1016/j.ccr.2005.02.011, 15766657
    • Pei D. Matrix metalloproteinases target protease-activated receptors on the tumor cell surface. Cancer Cell 2005, 7:207-8. 10.1016/j.ccr.2005.02.011, 15766657.
    • (2005) Cancer Cell , vol.7 , pp. 207-208
    • Pei, D.1
  • 68
    • 0037178853 scopus 로고    scopus 로고
    • Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL
    • 10.1074/jbc.M201207200, 12023955
    • Wurster AL, Rodgers VL, White MF, Rothstein TL, Grusby MJ. Interleukin-4-mediated protection of primary B cells from apoptosis through Stat6-dependent up-regulation of Bcl-xL. J Biol Chem 2002, 277:27169-75. 10.1074/jbc.M201207200, 12023955.
    • (2002) J Biol Chem , vol.277 , pp. 27169-27175
    • Wurster, A.L.1    Rodgers, V.L.2    White, M.F.3    Rothstein, T.L.4    Grusby, M.J.5
  • 70
    • 25844503817 scopus 로고    scopus 로고
    • Tumor immunity: a balancing act between T cell activation, macrophage activation and tumor-induced immune suppression
    • 10.1007/s00262-005-0703-4, 15877228
    • Sinha P, Clements VK, Miller S, Ostrand-Rosenberg S. Tumor immunity: a balancing act between T cell activation, macrophage activation and tumor-induced immune suppression. Cancer Immunol Immunother 2005, 54:1137-1142. 10.1007/s00262-005-0703-4, 15877228.
    • (2005) Cancer Immunol Immunother , vol.54 , pp. 1137-1142
    • Sinha, P.1    Clements, V.K.2    Miller, S.3    Ostrand-Rosenberg, S.4
  • 71
    • 0034544609 scopus 로고    scopus 로고
    • Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma
    • Ostrand-Rosenberg S, Grusby MJ, Clements VK. Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma. The Journal of Immunology 2000, 165:6015-19.
    • (2000) The Journal of Immunology , vol.165 , pp. 6015-6019
    • Ostrand-Rosenberg, S.1    Grusby, M.J.2    Clements, V.K.3
  • 72
    • 0037442009 scopus 로고    scopus 로고
    • Regression of a mammary adenocarcinoma in STAT6-/- mice is dependent on the presence of STAT6-reactive T cells
    • Jensen SM, Meijer SL, Kurt RA, Urba WJ, Hu HM, Fox BA. Regression of a mammary adenocarcinoma in STAT6-/- mice is dependent on the presence of STAT6-reactive T cells. The Journal of Immunology 2003, 170:2014-21.
    • (2003) The Journal of Immunology , vol.170 , pp. 2014-2021
    • Jensen, S.M.1    Meijer, S.L.2    Kurt, R.A.3    Urba, W.J.4    Hu, H.M.5    Fox, B.A.6
  • 74
    • 0034545618 scopus 로고    scopus 로고
    • Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice
    • Kacha AK, Fallarino F, Markiewicz MA, Gajewski TF. Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice. The Journal of Immunology 2000, 165:6024-28.
    • (2000) The Journal of Immunology , vol.165 , pp. 6024-6028
    • Kacha, A.K.1    Fallarino, F.2    Markiewicz, M.A.3    Gajewski, T.F.4
  • 75
    • 67649671865 scopus 로고    scopus 로고
    • DCVax-Brain and DC vaccines in the treatment of GBM
    • 10.1517/13543780902841951, 19335279
    • Wheeler CJ, Black KL. DCVax-Brain and DC vaccines in the treatment of GBM. Expert Opin Investig Drugs 2009, 18:509-519. 10.1517/13543780902841951, 19335279.
    • (2009) Expert Opin Investig Drugs , vol.18 , pp. 509-519
    • Wheeler, C.J.1    Black, K.L.2
  • 76
    • 42749088763 scopus 로고    scopus 로고
    • Cell- and peptide-based immunotherapeutic approaches for glioma
    • 10.1016/j.molmed.2008.03.003, 18403264
    • Yamanaka R. Cell- and peptide-based immunotherapeutic approaches for glioma. Trends in Molecular Medicine 2008, 14:228-235. 10.1016/j.molmed.2008.03.003, 18403264.
    • (2008) Trends in Molecular Medicine , vol.14 , pp. 228-235
    • Yamanaka, R.1


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