Nestin and CD133: Valuable stem cell-specific markers for determining clinical outcome of glioma patients

Journal of Experimental and Clinical Cancer Research

Volumn 27, Issue 1, 2008, Pages

  Zhang, Mingyu ^a   Song, Tao ^a   Yang, Liang ^a   Chen, Ruokun ^a   Wu, Lei ^a   Yang, Zhuanyi ^a   Fang, Jiasheng ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; NESTIN; GLYCOPROTEIN; INTERMEDIATE FILAMENT PROTEIN; LEUKOCYTE ANTIGEN; NERVE PROTEIN; PEPTIDE; TUMOR MARKER;

ADOLESCENT; ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER GRADING; CANCER PATIENT; CHILD; CONTROLLED STUDY; DISEASE MARKER; FEMALE; GLIOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; SCHOOL CHILD; STEM CELL; BIOSYNTHESIS; BRAIN TUMOR; CANCER STEM CELL; GENE EXPRESSION; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADOLESCENT; ADULT; AGED; ANTIGENS, CD; BRAIN NEOPLASMS; CHILD; FEMALE; GENE EXPRESSION; GLIOMA; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; MALE; MIDDLE AGED; NEOPLASTIC STEM CELLS; NERVE TISSUE PROTEINS; PEPTIDES; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 60149107175     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-27-85     Document Type: Article

References (30)

1. Stem Cell Markers in Gliomas. Paola Dell'Albani, Neurochem Res
2. Pathology and molecular genetics of astrocytic gliomas. G Reifenberger VP Collins, J Mol Med 2004 82 656 670 10.1007/s00109-004-0564-x 15316624
3. Molecular Biology of Gliomas. Andrew B Lassman, Current Neurology and Neuroscience Reports 2004 4 228 233 10.1007/s11910-004-0043-3
4. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. L Frederick XY Wang G Eley CD James, Cancer Res 2000 60 1383 1387 10728703
5. Prognostic value of Mdm2, p53 and p16 in patients with astrocytomas. SM Ranuncolo M Varela A Morandi J Lastiri S Christiansen, Journal of Neuro-Oncology 2004 68 113 121 10.1023/B:NEON.0000027741.19213.99 15218947
6. Prognostic and pathologic significance of quantitative protein expression profiling in human gliomas. AB Chakravarti MA Delaney E Noll PM Black JS Loeffler A Muzikansky NJ Dyson, Clin Cancer Res 2001 7 2387 2395 11489817
7. Adult neural stem cells: plasticity and developmental potential. A Gritti AL Vescovi R Galli, J Physiol Paris 2002 96 1-2 81 90 10.1016/S0928-4257(01) 00083-3 11755786
8. Identification of human brain tumour initiating cells. SK Singh C Hawkins ID Clarke JA Squire J Bayani T Hide RM Henkelman MD Cusimano PB Dirks, Nature 2004 432 396 401 10.1038/nature03128 15549107
9. Nestin Expression in Ganglioglioma. N Duggal RR Hammond, Experimental Neurology 2002 174 89 95 10.1006/exnr.2001.7838 11869037
10. Nestin as a diagnostic and prognostic marker: immunohistochemical analysis of its expression in different tumours. J Ehrmann Z Kola'r J Mokry, J Clin Pathol 2005 58 222 223 15677549 10.1136/jcp.2004.021238
11. CD133 Expression and Cancer Stem Cells Predict Prognosis in High-grade Oligodendroglial Tumors. D Beier J Wischhusen W Dietmaier P Hau M Proescholdt A Brawanski U Bogdahn CP Beier, Brain Pathology 2008 18 370 377 10.1111/j.1750-3639.2008.00130.x 18371181
12. Direct isolation of human central nervous system stem cells. N Uchida DW Buck D He MJ Reitsma M Masek TV Phan, Proc Natl Acad Sci USA 2000 97 14720 14725 11121071 10.1073/pnas.97.26.14720
13. Expression of stem cell markers in human astrocytomas of different WHO grades. Yue-Hui Ma Rolf Mentlein Friederike Knerlich Marie-Luise Kruse H Maximilian Mehdorn Janka Held-Feindt, J Neurooncol 2008 86 31 45 10.1007/s11060-007-9439-7 17611714
14. Expression of CD133 gene in gliomas and its correlation with malignancy of the tumor. X Liang D Peng L Qing, Chinese Journal of Minimally Invasive Neurosurgery 2008 13 128 130
15. Neural stem cell markers, nestin and musashi proteins, in the progression of human glioma: correlation of nestin with prognosis of patient survival. T Strojnik GV Rbsland PO Sakariassen R Kavalar T Lah, Surgical Neurology 2007 68 133 144 10.1016/j.surneu.2006.10.050 17537489
16. Nestin expression in different tumours and its relevance to malignant grade. XH Yang QL Wu XB Yu CX Xu BF Ma XM Zhang SN Li BT Lahn AP Xiang, J Clin Pathol 2008 61 467 473 10.1136/jcp.2007.047605 17873113
17. Outcome and patterns of failure following limited-volume irradiation for malignant astrocytomas. AS Garden MH Maor WK Yung, Radiother Oncol 1991 20 99 110 10.1016/0167-8140(91)90143-5 1851573
18. Isolation and characterization of tumourigenic, stem-like neural precursors from human glioblastoma. R Galli E Binda U Orfanelli B Cipelletti A Gritti S De Vitis R Fiocco C Foroni F Dimeco A Vescovi, Cancer Res 2004 64 7011 7021 10.1158/0008-5472.CAN-04-1364 15466194
19. Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody. CA Messam J Hou EO Major, Exp Neurol 2000 161 585 596 10.1006/exnr.1999.7319 10686078
20. Up regulation of nestin, vimentin, and desmin in rat podocytes in response to injury. J Zou E Yaoita Y Watanabe, Virchows Arch 2006 448 485 492 10.1007/s00428-005-0134-9 16418842
21. Nestin expression in reactive astrocytes of human pathology. I Tamagno D Schiffer, J Neurooncol 2006 80 227 233 10.1007/s11060-006-9181-6 16826367
22. Nestin expression in embryonic human neuroepithelium and in human neuroepithelial tumor cells. T Tohyama VM Lee LB Rorke M Marvin RDG McKay JQ Trojanowski, Lab Invest 1992 66 303 313 1538585
23. Nestin expression in the cell lines derived from glioblastoma multiforme. R Veselska P Kuglik P Cejpek H Svachova J Neradil T Loja J Relichova, BMC Cancer 2006 6 32 16457706 10.1186/1471-2407-6-32
24. Stem cell marker nestin and c-Jun NH2-terminal kinases in tumor and peritumor areas of glioblastoma multiforme: possible prognostic implications. A Mangiola G Lama C Giannitelli P De Bonis C Anile L Lauriola G La Torre G Sabatino G Maira M Jhanwar-Uniyal G Sica, Clin Cancer Res 2007 13 6970 6977 10.1158/1078-0432.CCR-07-1229 18056172
25. Immunohistochemical expression of nestin in the non-tumorous hypophysis and in pituitary neoplasms. F Rotondo K Kovacs E Horvath, Acta Neuropathol (Berl) 2006 111 272 277 10.1007/s00401-006-0031-6
26. Nestin expression in neuroepithelial tumors. D Schiffer A Manazza I Tamagno, Neurosci Lett 2006 34 80 85 10.1016/j.neulet.2006.02.034
27. CNS stem cells express a new class of intermediate filament protein. V Lendhal LB Zimmerman RD McKay, Cell 1990 60 585 595 10.1016/0092-8674(90)90662-X 1689217
28. Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. A Weigmann D Corbeil A Hellwig, Proc Natl Acad Sci USA 1997 94 12425 12430 9356465 10.1073/pnas.94.23.12425
29. Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cellderived progenitors. G Kania D Corbeil J Fuchs, Stem Cells 2005 23 791 804 10.1634/stemcells.2004-0232 15917475
30. Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133. SV Shmelkov L Jun R St. Clair, Blood 2004 103 2055 2061 10.1182/blood-2003-06-1881 14630820