Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein

Journal of Biological Chemistry

Volumn 288, Issue 4, 2013, Pages 2210-2222

  Shimizu, Akio ^a   Nakayama, Hironao ^a,c   Wang, Priscilla ^a   König, Courtney ^a   Akino, Tomoshige ^a   Sandlund, Johanna ^a   Coma, Silvia ^a   Italiano, Joseph E ^a,b   Mammoto, Akiko ^a   Bielenberg, Diane R ^a   Klagsbrun, Michael ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; CELL SIGNALING; CHEMICAL ACTIVATION; CYTOLOGY; ENDOTHELIAL CELLS; PROTEINS;

ANGIOGENESIS; CATHEPSIN B; CELL INVASION; CELL SURFACES; ELEMENT-BINDING PROTEINS; GLIOBLASTOMA CELLS; GLIOBLASTOMAS; IN-VIVO; INVASIVENESS; RESPONSE ELEMENTS;

TUMORS;

CATHEPSIN B; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NETRIN 1; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CELL INVASION; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GLIOBLASTOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TUMOR VASCULARIZATION;

EID: 84873813207     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.397398     Document Type: Article

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