The role of human tissue kallikreins 7 and 8 in intracranial malignancies

Biological Chemistry

Volumn 387, Issue 12, 2006, Pages 1607-1612

  Prezas, Panagiotis ^a   Scorilas, Andreas ^b   Yfanti, Christina ^a   Viktorov, Petar ^c   Agnanti, Niki ^d   Diamandis, Eleftherios ^e   Talieri, Maroulio ^a  

^a SAINT SAVVAS HOSPITAL   (Greece)

^b UNIVERSITY OF ATHENS   (Greece)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d UNIVERSITY OF IOANNINA   (Greece)

^e MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Brain cancer; HSCCE; Invasion; KLK7; KLK8; Neuropsin; Prognosis; Tumor markers

Indexed keywords

KALLIKREIN; KALLIKREIN 7; MESSENGER RNA; NEUROPSIN; PROTEIN HK7; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BRAIN CANCER; BREAST CANCER; CARCINOGENESIS; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MORPHOMETRICS; OVARY CANCER; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SKIN EXFOLIATION;

ADULT; BASE SEQUENCE; BRAIN NEOPLASMS; DNA PRIMERS; HUMANS; MIDDLE AGED; TISSUE KALLIKREINS;

EID: 33751549068     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.200     Document Type: Article

References (34)

1. Bhattacharjee, A., Richards, W.G., Staunton, J., Li, C., Monti, S., Vasa, P., Ladd, C., Behesti, J., Bueno, R., Gilette, M., et al. (2001). Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl. Acad. Sci. USA 98, 13790-13795.
2. Borgono, C.A. and Diamandis, E.P. (2004). The emerging roles of human kallikreins in cancer. Nat. Rev. Cancer 4, 876-890.
3. Brattsand, M., Steffansson, K., Lundh, C., Haasum, Y., and Egelrud, T. (2005). A proteolytic cascade of kallikreins in the stratum corneum. J. Invest. Dermatol. 124, 198-203.
4. Cane, S., Bignotti, E., Bellone, S., Palmieri, M., De las Casas, L., Roman, J.J., Pecorelli, S., Cannon, M.J., O'Brien, T., and Santin, A.D. (2004). The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/neuropsin/ovasin) is highly overexpressed in cervical cancer. Am. J. Obstet. Gynecol. 190, 60-66.
5. Cox, D.R. (1972). Regression models and life tables. R. Stat. Soc. B. 34, 187-202.
6. Del Rosso, M., Fibbi, G., Pucci, M., D'Alesio, S., Del Rosso, A., Magneli, L., and Chiarugi, V. (2002). Multiple pathways of cell invasion are regulated by multiple families of serine proteases. Clin. Exp. Metast. 19, 193-207.
7. Chung, C.H., Parker, J.S., Karaca, G., Wu, J., Funkhouser, W.K., Moore, D., Butterfoss, D., Xiang, D., Zanation, A., Yin, X., et al. (2004). Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cell 5, 489-500.
8. Diamandis, E.P., Yousef, G.M., Luo, L.Y., Magklara, A., and Obiezu, C. (2000). The new kallikrein gene family - implications in carginogenesis. Trends Endocrinol. Metab. 11, 54-60.
9. Diamandis, E.P., Scorilas, A., Kishi, T., Blennow, K., Luo, L.Y., Soosaipillai, A., Rademaker, A.W., and Sjogren, M. (2004). Altered kallikrein 7 and 10 concentrations in cerebrospinal fluid of patients with Alzheimer's disease and frontotemporal dementia. Clin. Biochem. 37, 230-237.
10. Davies, B., Kearns, I.R., Ure, J., Davies, C., and Lathe, R. (2001). Loss of hippocampal serine protease BSP1/neuropsin predisposes to global seizure activity. J. Neurosci. 21, 6993-7000.
11. Hansson, L., Strömqvist, M., Bäckman, A., Wallbrandt, P., Carlstein, A., and Egelrud, T. (1994). Cloning, expression and characterization of stratum corneum chymotryptic enzyme. J. Biol. Chem. 269, 19420-19426.
12. He, X.P., Shiosaka, S., and Yoshida, S. (2001). Expression of neuropsin in oligodendrocytes after injury to the CNS. Neurosci. Res. 39, 455-462.
13. Kaplan, E.L. and Meier, P. (1958). Nonparametric estimation from incomplete observations. J. Am. Stat. Assoc. 53, 457-481.
14. Kishi, T., Grass, L., Soosaipillai, A., Scorilas, A., Harbeck, N., Schmalfeldt, B., Dorn, J., Mysliwiec, M., Schmitt, M., and Diamandis, E.P. (2003a). Human kallikrein 8, a novel biomarker for ovarian carcinoma. Cancer Res. 63, 2771-2774.
15. Kishi, T., Grass, L., Soosaipillai, A., Shimizu-Okabe, C., and Diamandis, E.P. (2003b). Human kallikrein 8: immunoassay development and identification in tissue extracts and biological fluids. Clin. Chem. 49, 87-96.
16. Kishi, T., Soosaipillai, A., Grass, L., Little, S.P., Johnstone, E.M., and Diamandis, E.P. (2004). Development of an immunofluorometric assay and quantification of human kallikrein 7 in tissue extracts and biological fluids. Clin. Chem. 50, 709-716.
17. Kleihues, P. and Cavenee, W.K., eds. (2000). WHO Classification of Tumors (Lyon, France: IARC Press), pp. 6-70.
18. Kyriakopoulou, L.G., Yousef, G.M., Scorilas, A., Katsaros, D., Massobrio, M., Fracchioli, S., and Diamandis, E. (2003). Prognostic value of quantitatively assessed KLK7 expression in ovarian cancer. Clin. Biochem. 36, 135-143.
19. Landis, S.H., Murray, T., Bolden, S., and Wingo, P.A. (1998). Cancer statistics, 1998. CA Cancer J. Clin. 48, 6-29.
20. Liaw, L. and Crawford, H.C. (1999). Functions of the extracellular matrix and matrix degrading proteases during tumor progression. Braz. J. Med. Biol. Res. 32, 805-812.
21. Lundström, A. and Egelrud, T. (1991). Stratum corneum chymotryptic enzyme: a proteinase which may be generally present in the stratum corneum and with a possible involvement in desquamation. Acta Derm. Venereol. 71, 471-474.
22. Magklara, A., Scorilas, A., Katsaros, D., Massobrio, M., Yousef, G.M., Frachiolli, S., Danese, S., and Diamandis, E.P. (2001). The human KLK8 (neuropsin/ovasin) gene: identification of two novel splice variants and its prognostic value in ovarian cancer. Clin. Cancer Res. 7, 806-811.
23. Matsumoto-Miyai, K., Ninomiya, A., Yamasaki, H., Tamura, H., Nakamura, Y., and Shiosaka, S. (2003). NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin. J. Neurosci. 23, 7727-7736.
24. Prezas, P., Arlt, M.J.E., Viktorov, P., Soosaipillai, A., Holzscheiter, L., Schmitt, M., Talieri, M., Diamandis, E.P., Kruger, A., and Magdolen, V. (2006). Overexpression of the human tissue kallikrein genes KLK4, 5, 6, and 7 increases the malignant phenotype of ovarian cancer cells. Biol. Chem. 387, 807-811.
25. Rajapakse, S., Ogiwara, K., Takano, N., Moriyama, A., and Takahashi, T. (2005). Biochemical characterization of human kallikrein 8 and its possible involvement in the degradation of extracellular matrix proteins. FEBS Lett. 579, 6879-6884.
26. Roman-Gomez, J., Jimenez-Velasco, A., Agerre, X., Castillejo, J.A., Barrios, M., Andreu, E.J., Prosper, F., Heiniger, A., and Torres, A. (2004). The normal epithelial cell-specific 1 (NES1) gene, a candidate tumor suppressor gene on chromosome 19q13.3-4, is downregulated by hypermethylation in acute lymphoblastic leukemia. Leukemia 18, 362-365.
27. Shimizu-Okabe, C., M. Yousef, G.M., P. Diamandis, E.P., Yoshida, S., Shiosaka, S., and Fahnestock, M. (2001). Expression of the kallikrein gene family in normal and Alzheimer's disease brain. Neuroreport 12, 2747-2751.
28. Spiropoulou, T., Ferekidou, L., Angelopoulou, K., Stathopoulou, A., Talieri, M., and Lianidou, E.S. (2004). Effect of antineoplastic agents on the expression of human telomerase reverse transcriptase β plus transcript in MCF-7 cells. Clin. Biochem. 37, 299-304.
29. Talieri, M., Diamandis, E.P., Gourgiotis, D., Mathioudaki, K., and Scorilas, A. (2004). Expression analysis of the human kallikrein 7 (KLK7) in breast tumors: a new potential biomarker for prognosis of breast carcinoma. Thromb. Haemost. 91, 180-186.
30. Yoshida, S., Taniguchi, M., Hirata, A., and Shiosaka, S. (1998). Sequence analysis and expression of human neuropsin cDNA and gene. Gene 213, 9-16.
31. Yousef, G.M. and Diamandis, E.P. (2001). The new human tissue kallikrein family: structure, function and association to disease. Endocrine Rev. 22, 184-204.
32. Yousef, G.M., Scorilas, A., Magklara, A., Soosaipillai, A., and Diamandis, E.P. (2000). The KLK7 (PRSS6) gene, encoding for the stratum corneum chymotryptic enzyme, is a new member of the human kallikrein gene family - genomic characterization, mapping, tissue expression, and hormonal regulation. Gene 254, 119-128.
33. Yousef, G.M., Kishi, T., and Diamandis, E.P. (2003). Role of kallikrein enzymes in the central nervous system. Clin. Chim. Acta 329, 1-8.
34. Yousef, G.M. Borgono, C.A., Popalis, S., Yacoub, G.M., Polymeris, M.E., Soosaipillai, A., and Diamandis, E.P. (2004). In silico analysis of kallikrein gene expression in pancreatic and colon cancers. Anticancer Res. 24, 43-52.