The multivalent effect in glycosidase inhibition: A new, rapidly emerging topic in glycoscience

ChemBioChem

Volumn 15, Issue 9, 2014, Pages 1239-1251

  Compain, Philippe ^a,b   Bodlenner, Anne ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b INSTITUT UNIVERSITAIRE DE FRANCE   (France)

Author keywords

click chemistry; glycosidases; iminosugars; inhibitors; multivalency

Indexed keywords

ALPHA MANNOSIDASE; BETA CYCLODEXTRIN; GLUCOSIDASE; GLUCOSYLCERAMIDASE; GLYCOSIDASE INHIBITOR; LECTIN; MACROGOL; SIALIDASE; ENZYME INHIBITOR; GLYCOPROTEIN; GLYCOSIDASE;

ALMOND; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; CHEMICAL STRUCTURE; CLICK CHEMISTRY; CYCLOADDITION; CYSTIC FIBROSIS; DYNAMIC LIGHT SCATTERING; ENZYME ASSAY; ENZYME INHIBITION; GAUCHER DISEASE; LIGHT SCATTERING; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; X RAY CRYSTALLOGRAPHY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CONFORMATION; DOSE RESPONSE; DRUG DEVELOPMENT; GLYCOSYLATION; METABOLISM;

DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME INHIBITORS; GLYCOPROTEINS; GLYCOSIDE HYDROLASES; GLYCOSYLATION; MOLECULAR CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84902323914     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201402026     Document Type: Review

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