메뉴 건너뛰기




Volumn 12, Issue 14, 2012, Pages 1434-1442

Carbohydrate mimics and lectins: A source of new drugs and therapeutic opportunities

Author keywords

C type lectins and DC SIGN; Carbohydrates; Glycomimetics

Indexed keywords

CARBOHYDRATE DERIVATIVE; CD209 ANTIGEN; DENDRIMER; INTERCELLULAR ADHESION MOLECULE 3; LECTIN; MANNOSE; OLIGOSACCHARIDE; SCAFFOLD PROTEIN;

EID: 84873209047     PISSN: 13895575     EISSN: 18755607     Source Type: Journal    
DOI: 10.2174/138955712803832690     Document Type: Review
Times cited : (23)

References (104)
  • 6
    • 34250693209 scopus 로고    scopus 로고
    • Deciphering the glycocode: The complexity and analytical challenge of glycomics
    • Pilobello, K. T.; Mahal, L. K. Deciphering the glycocode: the complexity and analytical challenge of glycomics. Curr. Opin. Chem. Biol., 2007, 11, 300-305.
    • (2007) Curr. Opin. Chem. Biol. , vol.11 , pp. 300-305
    • Pilobello, K.T.1    Mahal, L.K.2
  • 9
    • 0035937499 scopus 로고    scopus 로고
    • Chemical Glycobiology
    • Bertozzi, C. R.; Kiessling, L. L. Chemical Glycobiology. Science, 2001, 291, 2357-2364.
    • (2001) Science , vol.291 , pp. 2357-2364
    • Bertozzi, C.R.1    Kiessling, L.L.2
  • 10
    • 33750949914 scopus 로고    scopus 로고
    • Carbohydrate Microarrays: Survey of Fabrication Techniques
    • Culf, A. S.; Cuperlovic-Culf, M.; Ouellette, R. J. Carbohydrate Microarrays: Survey of Fabrication Techniques. OMICS, 2006, 10, 289-310.
    • (2006) OMICS , vol.10 , pp. 289-310
    • Culf, A.S.1    Cuperlovic-Culf, M.2    Ouellette, R.J.3
  • 11
    • 33846385736 scopus 로고    scopus 로고
    • Emerging glycomics technologies
    • Turnbull, J. E.; Field, R. A. Emerging glycomics technologies. Nat Chem. Biol., 2007, 3, 74-77.
    • (2007) Nat Chem. Biol. , vol.3 , pp. 74-77
    • Turnbull, J.E.1    Field, R.A.2
  • 13
    • 84873143792 scopus 로고    scopus 로고
    • and links therein., see
    • see http://www.eurocarbdb.org and links therein.
  • 14
    • 35948955219 scopus 로고    scopus 로고
    • Exploring the Structural Diversity of Mammalian Carbohydrates ("Glycospace") by Statistical Databank Analysis
    • Werz, D.B.; Ranzinger, R.; Herget, S.; Adibekian, A.; vonder Lieth, C.-W.; Seeberger P.H. Exploring the Structural Diversity of Mammalian Carbohydrates ("Glycospace") by Statistical Databank Analysis. ACS Chem. Biol., 2007, 2, 685-691.
    • (2007) ACS Chem. Biol. , vol.2 , pp. 685-691
    • Werz, D.B.1    Ranzinger, R.2    Herget, S.3    Adibekian, A.4    vonder Lieth, C.-W.5    Seeberger, P.H.6
  • 15
    • 68249116079 scopus 로고    scopus 로고
    • From carbohydrate leads to glycomimetic drugs
    • Ernst, B.; Magnani, J. L. From carbohydrate leads to glycomimetic drugs. Nat. Rev. Drugs Discovery, 2009, 8, 661-677.
    • (2009) Nat. Rev. Drugs Discovery , vol.8 , pp. 661-677
    • Ernst, B.1    Magnani, J.L.2
  • 16
    • 53849126542 scopus 로고    scopus 로고
    • Interfering with the Sugar Code: Design and Synthesis of Oligosaccharide Mimics
    • Cheshev, P.; Bernardi, A. Interfering with the Sugar Code: Design and Synthesis of Oligosaccharide Mimics. Chem. Eur. J., 2008, 14, 7434-7441.
    • (2008) Chem. Eur. J. , vol.14 , pp. 7434-7441
    • Cheshev, P.1    Bernardi, A.2
  • 17
    • 0026654870 scopus 로고
    • Amino-sugar glycosidase inhibitors: Versatile tools for glycobiologists
    • Winchester, B.; Fleet, G.W.J. Amino-sugar glycosidase inhibitors: versatile tools for glycobiologists. Glycobiology, 1992, 2, 199-210.
    • (1992) Glycobiology , vol.2 , pp. 199-210
    • Winchester, B.1    Fleet, G.W.J.2
  • 18
    • 20444432200 scopus 로고    scopus 로고
    • Recent Advances in the Total Synthesis of Piperidine Azasugars
    • and references therein
    • Pearson, M.S.M.; Mathé-Allainmat, M.; Fargeas, V.; Lebreton, J. Recent Advances in the Total Synthesis of Piperidine Azasugars. Eur. J. Org. Chem., 2005, 2159-2191 and references therein.
    • (2005) Eur. J. Org. Chem. , pp. 2159-2191
    • Pearson, M.S.M.1    Mathé-Allainmat, M.2    Fargeas, V.3    Lebreton, J.4
  • 20
    • 79955456985 scopus 로고    scopus 로고
    • Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase
    • and references therein
    • Aguilar-Moncayo, M.; Garcia-Moreno, M. I.; Trapero, A.; Egido-Gabas, M.; Llebaria, A.; Garcia Fernandez, J. M.; Ortiz, C. Bicyclic (galacto)nojirimycin analogues as glycosidase inhibitors: Effect of structural modifications in their pharmacological chaperone potential towards β-glucocerebrosidase. Org. Biomol. Chem., 2011, 9, 3698-3713 and references therein.
    • (2011) Org. Biomol. Chem. , vol.9 , pp. 3698-3713
    • Aguilar-Moncayo, M.1    Garcia-Moreno, M.I.2    Trapero, A.3    Egido-Gabas, M.4    Llebaria, A.5    Garcia Fernandez, J.M.6    Ortiz, C.7
  • 21
    • 36749056771 scopus 로고    scopus 로고
    • The war against influenza: Discovery and development of sialidase inhibitors
    • von Itzstein, M. The war against influenza: discovery and development of sialidase inhibitors. Nat. Rev. Drug Discovery, 2007, 6, 967-974.
    • (2007) Nat. Rev. Drug Discovery , vol.6 , pp. 967-974
    • von Itzstein, M.1
  • 22
    • 40149094692 scopus 로고    scopus 로고
    • A Strategy to Discover Inhibitors of O-Linked Glycosylation
    • Gross, B.J.; Swoboda, J. G.; Walker, S. A Strategy to Discover Inhibitors of O-Linked Glycosylation. J. Am. Chem. Soc., 2008, 130, 440-441.
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 440-441
    • Gross, B.J.1    Swoboda, J.G.2    Walker, S.3
  • 23
    • 79952008246 scopus 로고    scopus 로고
    • A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics
    • Ghazarian, H.; Idoni, B.; Oppenheimer, S. B. A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics. Acta Histochemica, 2011, 113, 236-247.
    • (2011) Acta Histochemica , vol.113 , pp. 236-247
    • Ghazarian, H.1    Idoni, B.2    Oppenheimer, S.B.3
  • 24
    • 0031820273 scopus 로고    scopus 로고
    • The C-type lectin superfamily in the immune system
    • Weis W. I.; Taylor M. E.; Drickamer, K. The C-type lectin superfamily in the immune system. Immunol. Rev., 1998, 163, 19-34.
    • (1998) Immunol. Rev. , vol.163 , pp. 19-34
    • Weis, W.I.1    Taylor, M.E.2    Drickamer, K.3
  • 26
    • 33646782605 scopus 로고    scopus 로고
    • Inhibition and Detection of Galectins
    • Pieters, R. J. Inhibition and Detection of Galectins. ChemBioChem, 2006, 7, 721-728.
    • (2006) ChemBioChem , vol.7 , pp. 721-728
    • Pieters, R.J.1
  • 27
    • 7244258916 scopus 로고    scopus 로고
    • History of lectins: From hemagglutinins to biological recognition molecules
    • Sharon, N.; Lis, H. History of lectins: from hemagglutinins to biological recognition molecules. Glycobiology, 2004, 14, 53R-62R.
    • (2004) Glycobiology , vol.14
    • Sharon, N.1    Lis, H.2
  • 28
    • 77955778590 scopus 로고    scopus 로고
    • Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model
    • Sanchez-Ruderisch, H.; Fischer, C.; Detjen, K. M.; Welzel, M.; Wimmel, A.; Manning, J. C.; Andre, S.; Gabius, H.-J. Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model. FEBS J., 2010, 277, 3552-3563.
    • (2010) FEBS J. , vol.277 , pp. 3552-3563
    • Sanchez-Ruderisch, H.1    Fischer, C.2    Detjen, K.M.3    Welzel, M.4    Wimmel, A.5    Manning, J.C.6    Andre, S.7    Gabius, H.-J.8
  • 31
    • 0027318961 scopus 로고
    • Biological roles of oligosaccharides: All of the theories are correct
    • Varki, A. Biological roles of oligosaccharides: all of the theories are correct. Glycobiology, 1993, 3, 97-130.
    • (1993) Glycobiology , vol.3 , pp. 97-130
    • Varki, A.1
  • 32
    • 0001094662 scopus 로고    scopus 로고
    • Glycobiology: Toward Understanding the Function of Sugars
    • Dwek, R. A. Glycobiology: Toward Understanding the Function of Sugars. Chem. Rev., 1996, 96, 683-720.
    • (1996) Chem. Rev. , vol.96 , pp. 683-720
    • Dwek, R.A.1
  • 33
    • 0000358206 scopus 로고
    • Carbohydrate-Protein Interactions: Basis of Glycobiology
    • Lee, Y. C.; Lee, R. T. Carbohydrate-Protein Interactions: Basis of Glycobiology. Acc. Chem. Res., 1995, 28, 321-327.
    • (1995) Acc. Chem. Res. , vol.28 , pp. 321-327
    • Lee, Y.C.1    Lee, R.T.2
  • 34
    • 34247556420 scopus 로고    scopus 로고
    • Synthesis and medical applications of oligosaccharides
    • Seeberger, P. H.; Werz, D. B. Synthesis and medical applications of oligosaccharides. Nature, 2007, 446, 1046-1051.
    • (2007) Nature , vol.446 , pp. 1046-1051
    • Seeberger, P.H.1    Werz, D.B.2
  • 36
    • 79955018520 scopus 로고    scopus 로고
    • Carbohydrateprotein interactions: A 3D view by NMR
    • Roldos, V.; Canada, F. J.; Jiménez-Barbero, J. Carbohydrateprotein interactions: a 3D view by NMR. ChemBioChem, 2011, 12, 990-1005.
    • (2011) ChemBioChem , vol.12 , pp. 990-1005
    • Roldos, V.1    Canada, F.J.2    Jiménez-Barbero, J.3
  • 37
    • 79955782255 scopus 로고    scopus 로고
    • E-and P-Selectin: Differences, Similarities and Implications for the Design of P-Selectin Antagonists
    • Binder, F.P.C.; Ernst, B. E-and P-Selectin: Differences, Similarities and Implications for the Design of P-Selectin Antagonists. Chimia, 2011, 65, 210-213.
    • (2011) Chimia , vol.65 , pp. 210-213
    • Binder, F.P.C.1    Ernst, B.2
  • 38
    • 75749146598 scopus 로고    scopus 로고
    • Synthesis and Affinity Evaluation of a Small Library of Bidentate Cholera Toxin Ligands: Towards Nonhydrolyzable Ganglioside Mimics
    • Cheshev, P.; Morelli, L.; Marchesi, M.; Podlipnik, C.; Bergstrom, M.; Bernardi, A. Synthesis and Affinity Evaluation of a Small Library of Bidentate Cholera Toxin Ligands: Towards Nonhydrolyzable Ganglioside Mimics. Chemistry Eur. J., 2010, 16, 1951-1967.
    • (2010) Chemistry Eur. J. , vol.16 , pp. 1951-1967
    • Cheshev, P.1    Morelli, L.2    Marchesi, M.3    Podlipnik, C.4    Bergstrom, M.5    Bernardi, A.6
  • 39
    • 79955419711 scopus 로고    scopus 로고
    • Multifunctional multivalency: A focused library of polymeric cholera toxin antagonists
    • Tran, H.-A.; Kitov, P. I.; Paszkiewicz, E.; Sadowska, J. M.; Bundle, D. Multifunctional multivalency: a focused library of polymeric cholera toxin antagonists. Org. Biomol. Chem., 2011, 9, 3658-3671.
    • (2011) Org. Biomol. Chem. , vol.9 , pp. 3658-3671
    • Tran, H.-A.1    Kitov, P.I.2    Paszkiewicz, E.3    Sadowska, J.M.4    Bundle, D.5
  • 42
    • 79960340356 scopus 로고    scopus 로고
    • The Bacterial Lectin FimH, a Target for Drug Discovery-Carbohydrate Inhibitors of Type 1 Fimbriae-Mediated Bacterial Adhesion
    • and references therein
    • Hartmann M.; Lindhorst T. K. The Bacterial Lectin FimH, a Target for Drug Discovery-Carbohydrate Inhibitors of Type 1 Fimbriae-Mediated Bacterial Adhesion. Eur. J. Org. Chem., 2011, 3583-3609 and references therein.
    • (2011) Eur. J. Org. Chem. , pp. 3583-3609
    • Hartmann, M.1    Lindhorst, T.K.2
  • 49
    • 34249893345 scopus 로고    scopus 로고
    • Synthesis and conformational and biological aspects of carbasugars
    • Arjona, O.; Gómez, A. M.; López, J. C.; Plumet, J. Synthesis and conformational and biological aspects of carbasugars. Chem. Rev., 2007, 107, 1919-2036.
    • (2007) Chem. Rev. , vol.107 , pp. 1919-2036
    • Arjona, O.1    Gómez, A.M.2    López, J.C.3    Plumet, J.4
  • 50
    • 77957146063 scopus 로고    scopus 로고
    • Recent Advances in the Synthesis of Carbohydrate Mimetics
    • and references cited therein
    • Koester, D. C.; Holkenbrink, A.; Werz, D. B. Recent Advances in the Synthesis of Carbohydrate Mimetics. Synthesis, 2010, 19, 3217-3242 and references cited therein.
    • (2010) Synthesis , vol.19 , pp. 3217-3242
    • Koester, D.C.1    Holkenbrink, A.2    Werz, D.B.3
  • 51
    • 0000856193 scopus 로고    scopus 로고
    • Artificial Multivalent Sugar Ligands to Understand and Manipulate Carbohydrate-Protein Interactions
    • Lindhorst, T. K. Artificial Multivalent Sugar Ligands to Understand and Manipulate Carbohydrate-Protein Interactions. Top. Curr. Chem., 2002, 218, 201-235.
    • (2002) Top. Curr. Chem. , vol.218 , pp. 201-235
    • Lindhorst, T.K.1
  • 52
    • 5444233452 scopus 로고    scopus 로고
    • Interference with Lectin Binding and Bacterial Adhesion by Multivalent Carbohydrates and Peptidic Carbohydrate Mimics
    • Pieters, R. J. Interference with Lectin Binding and Bacterial Adhesion by Multivalent Carbohydrates and Peptidic Carbohydrate Mimics. Trends Glycosci. Glycotechnol., 2004, 16, 243-244.
    • (2004) Trends Glycosci. Glycotechnol. , vol.16 , pp. 243-244
    • Pieters, R.J.1
  • 53
    • 68949090634 scopus 로고    scopus 로고
    • Carbohydrate receptors of bacterial adhesins: Implications and reflections
    • Ohlsen, K.; Oelschlaeger, T. A.; Hacker, J.; Khan, A. S. Carbohydrate receptors of bacterial adhesins: implications and reflections. Top. Curr. Chem., 2009, 288, 17-65.
    • (2009) Top. Curr. Chem. , vol.288 , pp. 17-65
    • Ohlsen, K.1    Oelschlaeger, T.A.2    Hacker, J.3    Khan, A.S.4
  • 54
    • 52949100596 scopus 로고    scopus 로고
    • Recent trends in glycodendrimer syntheses and applications
    • Chabre, Y. M.; Roy, R. Recent trends in glycodendrimer syntheses and applications. Curr. Top. Med. Chem., 2008, 8, 1237-1285.
    • (2008) Curr. Top. Med. Chem. , vol.8 , pp. 1237-1285
    • Chabre, Y.M.1    Roy, R.2
  • 57
    • 35548948948 scopus 로고    scopus 로고
    • Non-Carbohydrate Inhibitors of the Lectin DC-SIGN
    • Borrok, M. J.; Kiessling, L. L. Non-Carbohydrate Inhibitors of the Lectin DC-SIGN. J. Am. Chem. Soc., 2007, 129, 12780-12785.
    • (2007) J. Am. Chem. Soc. , vol.129 , pp. 12780-12785
    • Borrok, M.J.1    Kiessling, L.L.2
  • 59
    • 0035834665 scopus 로고    scopus 로고
    • Reflections on glycobiology
    • Roseman, S. Reflections on glycobiology. J. Biol. Chem., 2001, 276, 41527-41542.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41527-41542
    • Roseman, S.1
  • 60
    • 0034465091 scopus 로고    scopus 로고
    • Modeling ganglioside headgroups by conformational analysis and molecular dynamics
    • Brocca, P.; Bernardi, A.; Raimondi, L.; Sonnino, S. Modeling ganglioside headgroups by conformational analysis and molecular dynamics. Glycoconjugate J., 2000, 17, 283-299.
    • (2000) Glycoconjugate J. , vol.17 , pp. 283-299
    • Brocca, P.1    Bernardi, A.2    Raimondi, L.3    Sonnino, S.4
  • 61
    • 22944433255 scopus 로고    scopus 로고
    • Threedimensional structures of carbohydrate determinants of Lewis system antigens: Implications for effective antibody targeting of cancer
    • Yuriev, E.; Farrugia, W.; Scott, A.M.; Ramsland, P.A. Threedimensional structures of carbohydrate determinants of Lewis system antigens: Implications for effective antibody targeting of cancer. Immunol. Cell Biol., 2005, 83, 709-717.
    • (2005) Immunol. Cell Biol. , vol.83 , pp. 709-717
    • Yuriev, E.1    Farrugia, W.2    Scott, A.M.3    Ramsland, P.A.4
  • 63
    • 0032476812 scopus 로고    scopus 로고
    • Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors
    • Mammen, M.; Choi, S.-K.; Whitesides, G. M. Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors. Angew. Chem. Int. Ed., 1998, 37, 2755-2794.
    • (1998) Angew. Chem. Int. Ed. , vol.37 , pp. 2755-2794
    • Mammen, M.1    Choi, S.-K.2    Whitesides, G.M.3
  • 65
    • 0034701264 scopus 로고    scopus 로고
    • High-affinity pentavalent ligands of Escherichia coli heat-labile enterotoxin by modular structure-based design
    • Fan, E. K.; Zhang, Z. S.; Minke, W. E.; Hou, Z.; Verlinde, C. L. M. J.; Hol, W. G. J. High-affinity pentavalent ligands of Escherichia coli heat-labile enterotoxin by modular structure-based design. J. Am. Chem. Soc., 2000, 122, 2663-2664.
    • (2000) J. Am. Chem. Soc. , vol.122 , pp. 2663-2664
    • Fan, E.K.1    Zhang, Z.S.2    Minke, W.E.3    Hou, Z.4    Verlinde, C.L.M.J.5    Hol, W.G.J.6
  • 66
    • 15744377412 scopus 로고    scopus 로고
    • A Synthetic Divalent Cholera Toxin Glycocalix[4]arene Ligand Having Higher Affinity than Natural GM1 Oligosaccharide
    • Arosio, D.; Fontanella, M.; Baldini, L.; Mauri, L; Bernardi, A.; Casnati, A.; Sansone, F.; Ungaro, R. A Synthetic Divalent Cholera Toxin Glycocalix[4]arene Ligand Having Higher Affinity than Natural GM1 Oligosaccharide. J. Am. Chem. Soc., 2005, 127, 3660-3661.
    • (2005) J. Am. Chem. Soc. , vol.127 , pp. 3660-3661
    • Arosio, D.1    Fontanella, M.2    Baldini, L.3    Mauri, L.4    Bernardi, A.5    Casnati, A.6    Sansone, F.7    Ungaro, R.8
  • 70
    • 12444347833 scopus 로고    scopus 로고
    • Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR
    • Feinberg, H.; Guo, Y.; Mitchell, D. A.; Drickamer, K.; Weis, W. I. Extended Neck Regions Stabilize Tetramers of the Receptors DC-SIGN and DC-SIGNR. J. Biol. Chem., 2005, 280, 1327-1335.
    • (2005) J. Biol. Chem. , vol.280 , pp. 1327-1335
    • Feinberg, H.1    Guo, Y.2    Mitchell, D.A.3    Drickamer, K.4    Weis, W.I.5
  • 71
    • 0035800757 scopus 로고    scopus 로고
    • A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR: Subunit organization and binding to multivalent ligands
    • Mitchell, D. A.; Fadden, A. J.; Drickamer, K. A novel mechanism of carbohydrate recognition by the C-type lectins DC-SIGN and DC-SIGNR: subunit organization and binding to multivalent ligands. J. Biol. Chem., 2001, 276, 28939-28945.
    • (2001) J. Biol. Chem. , vol.276 , pp. 28939-28945
    • Mitchell, D.A.1    Fadden, A.J.2    Drickamer, K.3
  • 74
    • 0036278649 scopus 로고    scopus 로고
    • C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in cis and in trans
    • Alvarez, C. P.; Lasala, F.; Carrillo, J.; Muniz, O.; Corbi, A. L.; Delgado, R. C-Type Lectins DC-SIGN and L-SIGN Mediate Cellular Entry by Ebola Virus in cis and in trans. J. Virol., 2002, 76, 6841-6844.
    • (2002) J. Virol. , vol.76 , pp. 6841-6844
    • Alvarez, C.P.1    Lasala, F.2    Carrillo, J.3    Muniz, O.4    Corbi, A.L.5    Delgado, R.6
  • 75
    • 35448944884 scopus 로고    scopus 로고
    • Specific Asparagine-Linked Glycosylation Sites Are Critical for DC-SIGN-and L-SIGNMediated Severe Acute Respiratory Syndrome Coronavirus Entry
    • Han, D. P.; Lohani, M.; Cho, M. W. Specific Asparagine-Linked Glycosylation Sites Are Critical for DC-SIGN-and L-SIGNMediated Severe Acute Respiratory Syndrome Coronavirus Entry. J. Virol., 2007, 81, 12029-12039.
    • (2007) J. Virol. , vol.81 , pp. 12029-12039
    • Han, D.P.1    Lohani, M.2    Cho, M.W.3
  • 79
    • 6344268943 scopus 로고    scopus 로고
    • Dendritic Cell-Specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin Mediates Binding and Internalization of Aspergillus fumigatus Conidia by Dendritic Cells and Macrophages
    • Serrano-Gomez, D.; Dominguez-Soto, A.; Ancochea, J.; Jimenez-Heffernan, J. A.; Leal, J. A.; Corbi, A. L. Dendritic Cell-Specific Intercellular Adhesion Molecule 3-Grabbing Nonintegrin Mediates Binding and Internalization of Aspergillus fumigatus Conidia by Dendritic Cells and Macrophages. J. Immunol., 2004, 173, 5635-5643.
    • (2004) J. Immunol. , vol.173 , pp. 5635-5643
    • Serrano-Gomez, D.1    Dominguez-Soto, A.2    Ancochea, J.3    Jimenez-Heffernan, J.A.4    Leal, J.A.5    Corbi, A.L.6
  • 80
    • 0037183983 scopus 로고    scopus 로고
    • Dendritic Cell (DC)-specific Intercellular Adhesion Molecule 3 (ICAM-3)-grabbing Nonintegrin (DC-SIGN, CD209), a C-type Surface Lectin in Human DCs, Is a Receptor for Leishmania Amastigotes
    • Colmenares, M.; Puig-Kroger, A.; Pello, O. M.; Corbi, A. L.; Rivas, L. Dendritic Cell (DC)-specific Intercellular Adhesion Molecule 3 (ICAM-3)-grabbing Nonintegrin (DC-SIGN, CD209), a C-type Surface Lectin in Human DCs, Is a Receptor for Leishmania Amastigotes. J. Biol. Chem., 2002, 277, 36766-36769.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36766-36769
    • Colmenares, M.1    Puig-Kroger, A.2    Pello, O.M.3    Corbi, A.L.4    Rivas, L.5
  • 81
    • 0037942767 scopus 로고    scopus 로고
    • The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis-x
    • van Die, I.; van Vliet, S. J.; Nyame, A. K.; Cummings, R. D.; Bank, C. M. C.; Appelmelk, B.; Geijtenbeek, T. B. H.; van Kooyk, Y. The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis-x. Glycobiology, 2003, 13, 471-478.
    • (2003) Glycobiology , vol.13 , pp. 471-478
    • van Die, I.1    van Vliet, S.J.2    Nyame, A.K.3    Cummings, R.D.4    Bank, C.M.C.5    Appelmelk, B.6    Geijtenbeek, T.B.H.7    van Kooyk, Y.8
  • 82
    • 77954677097 scopus 로고    scopus 로고
    • HIV microbicides: State of the art and new perspectives on the development of entry inhibitors
    • and references cited therein
    • Reina, J. J.; Bernardi, A.; Clerici, M.; Rojo, J. HIV microbicides: state of the art and new perspectives on the development of entry inhibitors. Fut. Med. Chem., 2010, 2, 1141-1159 and references cited therein.
    • (2010) Fut. Med. Chem. , vol.2 , pp. 1141-1159
    • Reina, J.J.1    Bernardi, A.2    Clerici, M.3    Rojo, J.4
  • 83
    • 79952279325 scopus 로고    scopus 로고
    • Targeting DC-SIGN with carbohydrate multivalent systems
    • Sánchez-Navarro, M.; Rojo J. Targeting DC-SIGN with carbohydrate multivalent systems. Drugs News & Perspectives, 2010, 23, 557-572.
    • (2010) Drugs News & Perspectives , vol.23 , pp. 557-572
    • Sánchez-Navarro, M.1    Rojo, J.2
  • 84
    • 33947493929 scopus 로고    scopus 로고
    • Multiple Modes of Binding Enhance the Affinity of DC-SIGN for High Mannose N-Linked Glycans Found on Viral Glycoproteins
    • Feinberg, H.; Castelli, R.; Drickamer, K.; Seeberger, P. H.; Weis, W. I. Multiple Modes of Binding Enhance the Affinity of DC-SIGN for High Mannose N-Linked Glycans Found on Viral Glycoproteins. J. Biol. Chem., 2007, 282, 4202-4209.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4202-4209
    • Feinberg, H.1    Castelli, R.2    Drickamer, K.3    Seeberger, P.H.4    Weis, W.I.5
  • 86
    • 0035824446 scopus 로고    scopus 로고
    • Structural Basis for Selective Recognition of Oligosaccharides by DC-SIGN and DC-SIGNR
    • Feinberg, H.; Mitchell, D. A.; Drickamer, K.; Weis, W. I. Structural Basis for Selective Recognition of Oligosaccharides by DC-SIGN and DC-SIGNR. Science, 2001, 294, 2163-2166.
    • (2001) Science , vol.294 , pp. 2163-2166
    • Feinberg, H.1    Mitchell, D.A.2    Drickamer, K.3    Weis, W.I.4
  • 88
    • 3042646556 scopus 로고    scopus 로고
    • Oligosaccharide and Glycoprotein Microarrays as Tools in HIV Glycobiology: Glycan-Dependent gp120/Protein Interactions
    • Adams, E. W.; Ratner, D. M.; Bokesch, H. R.; McMahon, J. B.; O'Keefe, B. R.; Seeberger, P. H. Oligosaccharide and Glycoprotein Microarrays as Tools in HIV Glycobiology: Glycan-Dependent gp120/Protein Interactions. Chem. Biol., 2004, 11, 875-881.
    • (2004) Chem. Biol. , vol.11 , pp. 875-881
    • Adams, E.W.1    Ratner, D.M.2    Bokesch, H.R.3    McMahon, J.B.4    O'Keefe, B.R.5    Seeberger, P.H.6
  • 93
    • 0344011988 scopus 로고    scopus 로고
    • Mannosyl Glycodendritic Structure Inhibits DC-SIGN-Mediated Ebola Virus Infection in cis and in trans
    • Lasala, F.; Arce, E.; Otero, J. R.; Rojo, J.; Delgado, R. Mannosyl Glycodendritic Structure Inhibits DC-SIGN-Mediated Ebola Virus Infection in cis and in trans. Antimicrob. Agents Chemother., 2003, 47, 3970-3972.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 3970-3972
    • Lasala, F.1    Arce, E.2    Otero, J.R.3    Rojo, J.4    Delgado, R.5
  • 98
    • 77956314446 scopus 로고    scopus 로고
    • A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN
    • Garber, K. C. A.; Wangkanont, K.; Carlson, E. E.; Kiessling, L. L. A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN. Chem. Comm., 2010, 46, 6747-6749.
    • (2010) Chem. Comm. , vol.46 , pp. 6747-6749
    • Garber, K.C.A.1    Wangkanont, K.2    Carlson, E.E.3    Kiessling, L.L.4
  • 100
    • 77953635153 scopus 로고    scopus 로고
    • Chemical Approaches to Glycobiology
    • Kiessling, L. L.; Splain, R. A. Chemical Approaches to Glycobiology. Annu. Rev. Biochem., 2010, 79, 619-653.
    • (2010) Annu. Rev. Biochem. , vol.79 , pp. 619-653
    • Kiessling, L.L.1    Splain, R.A.2
  • 104
    • 77956229815 scopus 로고    scopus 로고
    • An assay for functional dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) inhibitors of human dendritic cell adhesion
    • Obermajer, N.; Svajger, U.; Jeras, M.; Sattin, S.; Bernardi, A.; Anderluh, M. An assay for functional dendritic cell-specific ICAM-3-grabbing nonintegrin (DC-SIGN) inhibitors of human dendritic cell adhesion. Anal. Biochem., 2010, 406, 222-229.
    • (2010) Anal. Biochem. , vol.406 , pp. 222-229
    • Obermajer, N.1    Svajger, U.2    Jeras, M.3    Sattin, S.4    Bernardi, A.5    Anderluh, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.