The multivalent effect in glycosidase inhibition: Probing the influence of architectural parameters with cyclodextrin-based iminosugar click clusters

Chemistry - A European Journal

Volumn 17, Issue 49, 2011, Pages 13825-13831

  Decroocq, Camille ^a   Rodríguez Lucena, David ^a   Russo, Virginie ^a   Mena Barragán, Teresa ^b   Ortiz Mellet, Carmen ^b   Compain, Philippe ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY OF SEVILLE   (Spain)

Author keywords

click chemistry; cyclodextrins; glycosidases; iminosugars; inhibitors

Indexed keywords

ACTIVE SITE; ARCHITECTURAL PARAMETERS; AZIDE-ALKYNE CYCLOADDITION; CLICK CHEMISTRY; FOUR-ORDER; GLYCOMIMETIC; GLYCOSIDASE INHIBITION; GLYCOSIDASE INHIBITORS; GLYCOSIDASES; IMINOSUGARS; MANNOSIDASE; MICROWAVE ACTIVATION; MULTIVALENCY; MULTIVALENT BINDING; MULTIVALENT EFFECT; RECOGNITION PROCESS;

ACETYLENE; CARBOHYDRATES; CORROSION INHIBITORS; CYCLOADDITION; CYCLODEXTRINS; SYNTHESIS (CHEMICAL);

ENZYME INHIBITION;

BETA CYCLODEXTRIN DERIVATIVE; COPPER; GLYCOSIDASE; IMINOSUGAR;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CLICK CHEMISTRY; DRUG ANTAGONISM;

BETA-CYCLODEXTRINS; CATALYSIS; CLICK CHEMISTRY; COPPER; GLYCOSIDE HYDROLASES; IMINO SUGARS; MODELS, MOLECULAR;

EID: 82455192839     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201102266     Document Type: Article

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