Highly potent and long-acting trimeric and tetrameric inhibitors of influenza virus neuraminidase

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1589-1592

  Watson, Keith G ^a,d   Cameron, Rachel ^c   Fenton, Rob J ^b   Gower, David ^b   Hamilton, Stephanie ^c   Jin, Betty ^a   Krippner, Guy Y ^a   Luttick, Angela ^c   McConnell, Darryl ^a   MacDonald, Simon J F ^b   Mason, Andy M ^b   Nguyen, Van ^a   Tucker, Simon P ^c   Wu, Wen Yang ^a  

^a MONASH UNIVERSITY   (Australia)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Biota Holdings Limited   (Australia)

^d WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; MONOMER; POLYMER; TETRAMER; VIRUS SIALIDASE; ZANAMIVIR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CROSS COUPLING REACTION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; EXPERIMENTAL MODEL; INFLUENZA; INFLUENZA VIRUS; MOUSE; NONHUMAN; PROTECTION; STATISTICAL SIGNIFICANCE; VIRUS INFECTION;

ANIMALS; ANTIVIRAL AGENTS; ENZYME INHIBITORS; GUANIDINES; INFLUENZA A VIRUS; MICE; NEURAMINIDASE; ORTHOMYXOVIRIDAE INFECTIONS; PYRANS; SIALIC ACIDS; ZANAMIVIR;

INFLUENZA VIRUS;

EID: 10744221268     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.09.102     Document Type: Article

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