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Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 15, 2002, Pages 1929-1932

Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives

(5) Honda, Takeshi a Yoshida, Shuku a Arai, Masami a Masuda, Takeshi a Yamashita, Makoto a

a DAIICHI SANKYO CO (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL ETHER; ANTIVIRUS AGENT; GUANIDINE DERIVATIVE; NEURAMINIC ACID DERIVATIVE; POLYGLUTAMIC ACID; SIALIDASE INHIBITOR; VIRUS SIALIDASE; ZANAMIVIR; 2-DEOXY-2,3-DEHYDRO-N-ACETYLNEURAMINIC ACID; DRUG DERIVATIVE; ENZYME INHIBITOR; GLUTAMIC ACID; GLYCEROL ETHER; GUANIDINE; N ACETYL 2,3 DIDEHYDRO 2 DEOXYNEURAMINIC ACID; N ACETYLNEURAMINIC ACID; PYRAN DERIVATIVE; SIALIC ACID DERIVATIVE; SIALIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; IN VIVO STUDY; INFLUENZA; INFLUENZA VIRUS A; MOUSE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; ANIMAL; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; IC 50; ORTHOMYXOVIRUS INFECTION; SYNTHESIS; VIRUS CULTURE;

ANIMAL; ANTIVIRAL AGENTS; ENZYME INHIBITORS; GLUTAMIC ACID; GLYCERYL ETHERS; GUANIDINE; INFLUENZA; INFLUENZA A VIRUS; INHIBITORY CONCENTRATION 50; MICE; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; PLAQUE ASSAY; SIALIC ACIDS; STRUCTURE-ACTIVITY RELATIONSHIP; ANIMALS; GUANIDINES; ORTHOMYXOVIRIDAE INFECTIONS; PYRANS; ZANAMIVIR;

EID: 0037025441 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(02)00330-X Document Type: Article

Times cited : (67)

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