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Volumn 66, Issue 4, 2014, Pages 507-530

Topical delivery of ocular therapeutics: Carrier systems and physical methods

Author keywords

contact lens; dendrimers; iontophoresis; nanoparticle; topical ocular delivery

Indexed keywords

CONTACT LENS; DENDRIMERS; IONTOPHORESIS; NANOPARTICLE; TOPICAL OCULAR DELIVERY;

EID: 84899090733     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12132     Document Type: Review
Times cited : (111)

References (283)
  • 1
    • 34249787025 scopus 로고    scopus 로고
    • Ocular drug delivery: Nanomedicine applications
    • Vandervoort J, Ludwig A,. Ocular drug delivery: nanomedicine applications. Nanomedicine 2007; 2: 11-21.
    • (2007) Nanomedicine , vol.2 , pp. 11-21
    • Vandervoort, J.1    Ludwig, A.2
  • 2
    • 77958198693 scopus 로고    scopus 로고
    • Ocular drug delivery
    • etal.
    • Gaudana R, etal. Ocular drug delivery. AAPS J 2010; 12: 348-360.
    • (2010) AAPS J , vol.12 , pp. 348-360
    • Gaudana, R.1
  • 3
    • 28444444139 scopus 로고    scopus 로고
    • Topical and systemic drug delivery to the posterior segments
    • etal.
    • Hughes PM, etal. Topical and systemic drug delivery to the posterior segments. Adv Drug Deliv Rev 2005; 57: 2010-2032.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 2010-2032
    • Hughes, P.M.1
  • 4
    • 63949084823 scopus 로고    scopus 로고
    • Recent perspectives in ocular drug delivery
    • etal.
    • Gaudana R, etal. Recent perspectives in ocular drug delivery. Pharm Res 2009; 26: 1197-1216.
    • (2009) Pharm Res , vol.26 , pp. 1197-1216
    • Gaudana, R.1
  • 5
    • 0031965225 scopus 로고    scopus 로고
    • Ophthalmic drug delivery systems recent advances
    • etal.
    • Le-Bourlais CL, etal. Ophthalmic drug delivery systems recent advances. Prog Retin Eye Res 1998; 17: 33-58.
    • (1998) Prog Retin Eye Res , vol.17 , pp. 33-58
    • Le-Bourlais, C.L.1
  • 6
    • 0037319276 scopus 로고    scopus 로고
    • Drug delivery to the retina: Challenges and opportunities
    • etal.
    • Duvvuri S, etal. Drug delivery to the retina: challenges and opportunities. Expert Opin Biol Ther 2003; 3: 45-56.
    • (2003) Expert Opin Biol Ther , vol.3 , pp. 45-56
    • Duvvuri, S.1
  • 7
    • 63949084933 scopus 로고    scopus 로고
    • Prediction of vitreal half-life based on drug physicochemical properties: Quantitative structure-pharmacokinetic relationships (QSPKR)
    • etal.
    • Durajai C, etal. Prediction of vitreal half-life based on drug physicochemical properties: quantitative structure-pharmacokinetic relationships (QSPKR). Pharm Res 2009; 26: 1236-1260.
    • (2009) Pharm Res , vol.26 , pp. 1236-1260
    • Durajai, C.1
  • 8
    • 0026542156 scopus 로고
    • Hydrogel: Swelling, drug loading and release
    • etal.
    • Kim SW, etal. Hydrogel: swelling, drug loading and release. Pharm Res 1992; 9: 283-290.
    • (1992) Pharm Res , vol.9 , pp. 283-290
    • Kim, S.W.1
  • 9
    • 31544455253 scopus 로고    scopus 로고
    • Treatment of cytomegalovirus retinitis in AIDS patients with intravitreal ganciclovir
    • etal.
    • Ausayakhun S, etal. Treatment of cytomegalovirus retinitis in AIDS patients with intravitreal ganciclovir. J Med Assoc Thai 2005; 88 (Suppl. 9): bS15-bS20.
    • (2005) J Med Assoc Thai , vol.88 , Issue.SUPPL. 9
    • Ausayakhun, S.1
  • 10
    • 78650582969 scopus 로고    scopus 로고
    • Applications of nanoparticles in ophthalmology
    • Diebold I, Calone M,. Applications of nanoparticles in ophthalmology. Prog Retin Eye Res 2010; 29: 596-609.
    • (2010) Prog Retin Eye Res , vol.29 , pp. 596-609
    • Diebold, I.1    Calone, M.2
  • 11
    • 79954520410 scopus 로고    scopus 로고
    • Recent advances in ophthalmic drug delivery
    • etal.
    • Kompella UB, etal. Recent advances in ophthalmic drug delivery. Ther Deliv 2010; 1: 435-456.
    • (2010) Ther Deliv , vol.1 , pp. 435-456
    • Kompella, U.B.1
  • 12
    • 80052762003 scopus 로고    scopus 로고
    • Nanotechnology in ocular delivery: Current and future directions
    • etal.
    • Sultana Y, etal. Nanotechnology in ocular delivery: current and future directions. Drugs Today (Barc) 2011; 47: 441-455.
    • (2011) Drugs Today (Barc) , vol.47 , pp. 441-455
    • Sultana, Y.1
  • 13
    • 84883219531 scopus 로고    scopus 로고
    • Nanomedicines for back of the eye drug delivery, gene delivery, and imaging
    • etal.
    • Kompella UB, etal. Nanomedicines for back of the eye drug delivery, gene delivery, and imaging. Prog Retin Eye Res 2013; 36: 172-198.
    • (2013) Prog Retin Eye Res , vol.36 , pp. 172-198
    • Kompella, U.B.1
  • 14
    • 84874679837 scopus 로고    scopus 로고
    • Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers
    • etal.
    • Gan L, etal. Recent advances in topical ophthalmic drug delivery with lipid-based nanocarriers. Drug Discov Today 2013; 18: 290-297.
    • (2013) Drug Discov Today , vol.18 , pp. 290-297
    • Gan, L.1
  • 15
    • 84875021551 scopus 로고    scopus 로고
    • Novel strategies for anterior segment ocular drug delivery
    • etal.
    • Cholkar K, etal. Novel strategies for anterior segment ocular drug delivery. J Ocul Pharmacol Ther 2013; 29: 106-123.
    • (2013) J Ocul Pharmacol Ther , vol.29 , pp. 106-123
    • Cholkar, K.1
  • 16
    • 0034614208 scopus 로고    scopus 로고
    • Microemulsion-based media as novel drug delivery systems
    • Lawrence MJ, Rees GD,. Microemulsion-based media as novel drug delivery systems. Adv Drug Deliv Rev 2000; 45: 89-121.
    • (2000) Adv Drug Deliv Rev , vol.45 , pp. 89-121
    • Lawrence, M.J.1    Rees, G.D.2
  • 17
    • 84865373725 scopus 로고    scopus 로고
    • Microemulsions as delivery systems
    • Fanun M,. Microemulsions as delivery systems. Curr Opin Colloid Interface Sci 2012; 17: 306-313.
    • (2012) Curr Opin Colloid Interface Sci , vol.17 , pp. 306-313
    • Fanun, M.1
  • 18
    • 84899472603 scopus 로고    scopus 로고
    • Cutaneous drug delivery using nano/Microsystems combined with physical methods for permeation enhancement
    • etal. Lopez R.F.V. etal., eds. Kelara: Transworld Research Network.
    • Gratieri T, etal. Cutaneous drug delivery using nano/Microsystems combined with physical methods for permeation enhancement. In:, Lopez RFV, etal., eds. Physical Methods to Increase Topical and Transdermal Drug Delivery. Kelara: Transworld Research Network, 2012: 161-191.
    • (2012) Physical Methods to Increase Topical and Transdermal Drug Delivery , pp. 161-191
    • Gratieri, T.1
  • 19
    • 77951652824 scopus 로고    scopus 로고
    • Development of microemulsions to topically deliver 5-aminolevulinic acid in photodynamic therapy
    • etal.
    • Araújo LM, etal. Development of microemulsions to topically deliver 5-aminolevulinic acid in photodynamic therapy. Eur J Pharm Biopharm 2010; 75: 48-55.
    • (2010) Eur J Pharm Biopharm , vol.75 , pp. 48-55
    • Araújo, L.M.1
  • 20
    • 0036130360 scopus 로고    scopus 로고
    • Microemulsions as ocular drug delivery systems: Recent developmentsand future challenges
    • Vandamme THF,. Microemulsions as ocular drug delivery systems: recent developmentsand future challenges. Prog Retin Eye Res 2002; 21: 15-34.
    • (2002) Prog Retin Eye Res , vol.21 , pp. 15-34
    • Vandamme, T.H.F.1
  • 21
    • 80052029739 scopus 로고    scopus 로고
    • Engineering tenofovir loaded chitosan nanoparticles to maximize microbicide mucoadhesion
    • etal.
    • Meng J, etal. Engineering tenofovir loaded chitosan nanoparticles to maximize microbicide mucoadhesion. Eur J Pharm Sci 2011; 44: 57-67.
    • (2011) Eur J Pharm Sci , vol.44 , pp. 57-67
    • Meng, J.1
  • 22
    • 70350618790 scopus 로고    scopus 로고
    • Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation
    • etal.
    • Yin YM, etal. Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation. J Control Release 2009; 140: 86-94.
    • (2009) J Control Release , vol.140 , pp. 86-94
    • Yin, Y.M.1
  • 23
    • 0029347459 scopus 로고
    • Ocular absorption following topical delivery
    • etal.
    • Jarvinen K, etal. Ocular absorption following topical delivery. Adv Drug Deliv Rev 1995; 16: 3-19.
    • (1995) Adv Drug Deliv Rev , vol.16 , pp. 3-19
    • Jarvinen, K.1
  • 25
    • 0024354972 scopus 로고
    • Microemulsions as topical delivery vehicles: Ocular administration of timolol
    • etal.
    • Gasco MR, etal. Microemulsions as topical delivery vehicles: ocular administration of timolol. J Pharm Biomed Anal 1989; 7: 433-439.
    • (1989) J Pharm Biomed Anal , vol.7 , pp. 433-439
    • Gasco, M.R.1
  • 26
    • 33344461703 scopus 로고    scopus 로고
    • W/O microemulsions for ocular delivery: Evaluation of ocular irritation and precorneal retention
    • etal.
    • Alany RG, etal. W/O microemulsions for ocular delivery: evaluation of ocular irritation and precorneal retention. J Control Release 2006; 11: 145-152.
    • (2006) J Control Release , vol.11 , pp. 145-152
    • Alany, R.G.1
  • 27
    • 79952235696 scopus 로고    scopus 로고
    • Effect of water-in-oil microemulsions and lamellar liquid crystalline systems on the precorneal tear film of albino New Zealand rabbits
    • etal.
    • Chan J, etal. Effect of water-in-oil microemulsions and lamellar liquid crystalline systems on the precorneal tear film of albino New Zealand rabbits. Clin Ophthalmol 2008; 2: 129-138.
    • (2008) Clin Ophthalmol , vol.2 , pp. 129-138
    • Chan, J.1
  • 28
    • 37849188724 scopus 로고    scopus 로고
    • Phase transition water-in-oil microemulsions as ocular drug delivery systems: In vitro and in vivo evaluation
    • etal.
    • Chan J, etal. Phase transition water-in-oil microemulsions as ocular drug delivery systems: in vitro and in vivo evaluation. Int J Pharm 2007; 328: 65-71.
    • (2007) Int J Pharm , vol.328 , pp. 65-71
    • Chan, J.1
  • 29
    • 57049179056 scopus 로고    scopus 로고
    • Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: In vitro and in vivo results
    • etal.
    • Gan L, etal. Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results. Int J Pharm 2009; 365: 143-149.
    • (2009) Int J Pharm , vol.365 , pp. 143-149
    • Gan, L.1
  • 30
    • 0028110468 scopus 로고
    • Pilocarpine incorporated into a submicron emulsion vehicle causes an unexpectedly prolonged ocular hypotensive effect in rabbits
    • etal.
    • Naveh N, etal. Pilocarpine incorporated into a submicron emulsion vehicle causes an unexpectedly prolonged ocular hypotensive effect in rabbits. J Ocul Pharmacol 1994; 10: 509-520.
    • (1994) J Ocul Pharmacol , vol.10 , pp. 509-520
    • Naveh, N.1
  • 31
    • 0001061442 scopus 로고
    • Pilocarpine in submicron emulsion formulation for treatment of ocular hypertension: A phase II clinical trial
    • Garty N, Lusky M,. Pilocarpine in submicron emulsion formulation for treatment of ocular hypertension: a phase II clinical trial. Invest Ophthalmol Vis Sci 1994; 35: 2175-2179.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 2175-2179
    • Garty, N.1    Lusky, M.2
  • 32
    • 0006505549 scopus 로고
    • Ocular retention time of submicron emulsion (SME) and the miotic response to pilocarpine delivered in SME
    • etal.
    • Beilin M, etal. Ocular retention time of submicron emulsion (SME) and the miotic response to pilocarpine delivered in SME. Invest Ophthalmol Vis Sci 1995; 36: S166.
    • (1995) Invest Ophthalmol Vis Sci , vol.36
    • Beilin, M.1
  • 33
    • 84874484429 scopus 로고    scopus 로고
    • Mucoadhesive chitosan-coated cationic microemulsion of dexamethasone for ocular delivery: In vitro and in vivo evaluation
    • etal.
    • Kesavan K, etal. Mucoadhesive chitosan-coated cationic microemulsion of dexamethasone for ocular delivery: in vitro and in vivo evaluation. Curr Eye Res 2012; 38: 342-352.
    • (2012) Curr Eye Res , vol.38 , pp. 342-352
    • Kesavan, K.1
  • 34
    • 84861657127 scopus 로고    scopus 로고
    • Ocular antisense oligonucleotide delivery by cationic nanoemulsion for improved treatment of ocular neovascularization: An in vivo study in rats and mice
    • etal.
    • Hagigit T, etal. Ocular antisense oligonucleotide delivery by cationic nanoemulsion for improved treatment of ocular neovascularization: an in vivo study in rats and mice. J Control Release 2012; 160: 225-231.
    • (2012) J Control Release , vol.160 , pp. 225-231
    • Hagigit, T.1
  • 35
    • 84865819679 scopus 로고    scopus 로고
    • Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb
    • etal.:604204.
    • Lallemand F, etal. Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb. J Drug Deliv 2012; 2012:604204: 1-16.
    • (2012) J Drug Deliv , vol.2012 , pp. 1-16
    • Lallemand, F.1
  • 36
    • 77954314021 scopus 로고    scopus 로고
    • Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye
    • etal.
    • Hagigit T, etal. Topical and intravitreous administration of cationic nanoemulsions to deliver antisense oligonucleotides directed towards VEGF KDR receptors to the eye. J Control Release 2010; 145: 297-305.
    • (2010) J Control Release , vol.145 , pp. 297-305
    • Hagigit, T.1
  • 37
    • 50149113069 scopus 로고    scopus 로고
    • The influence of cationic lipid type on in-vitro release kinetic profiles of antisense oligonucleotide from cationic nanoemulsions
    • etal.
    • Hagigit T, etal. The influence of cationic lipid type on in-vitro release kinetic profiles of antisense oligonucleotide from cationic nanoemulsions. Eur J Pharm Biopharm 2008; 70: 248-259.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 248-259
    • Hagigit, T.1
  • 38
    • 34249291291 scopus 로고    scopus 로고
    • Mechanism of adjuvant activity of cationic liposome: Phosphorylation of a MAP kinase, ERK and induction of chemokines
    • etal.
    • Yan W, etal. Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokines. Mol Immunol 2007; 44: 3672-3681.
    • (2007) Mol Immunol , vol.44 , pp. 3672-3681
    • Yan, W.1
  • 39
    • 84865293742 scopus 로고    scopus 로고
    • Liposomal diclofenac eye drop formulations targeting the retina: Formulation stability improvement using surface modification of liposomes
    • etal.
    • Fujisawa T, etal. Liposomal diclofenac eye drop formulations targeting the retina: formulation stability improvement using surface modification of liposomes. Int J Pharm 2012; 436: 564-567.
    • (2012) Int J Pharm , vol.436 , pp. 564-567
    • Fujisawa, T.1
  • 40
    • 55749086377 scopus 로고    scopus 로고
    • Polyoxyethylated nonionic surfactants and their application in topical ocular drug delivery
    • Jiao J,. Polyoxyethylated nonionic surfactants and their application in topical ocular drug delivery. Adv Drug Deliv Rev 2008; 60: 1663-1673.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1663-1673
    • Jiao, J.1
  • 41
    • 79961158933 scopus 로고    scopus 로고
    • Influence of acetazolamide loading on the (in vitro) performances of non-phospholipid-based cationic nanosized emulsion in comparison with phospholipid-based anionic and neutral-charged nanosized emulsions
    • Tamilvanan S, Kumar BA,. Influence of acetazolamide loading on the (in vitro) performances of non-phospholipid-based cationic nanosized emulsion in comparison with phospholipid-based anionic and neutral-charged nanosized emulsions. Drug Dev Ind Pharm 2011; 37: 1003-1015.
    • (2011) Drug Dev Ind Pharm , vol.37 , pp. 1003-1015
    • Tamilvanan, S.1    Kumar, B.A.2
  • 42
    • 67650751095 scopus 로고    scopus 로고
    • Mucoadhesive properties of chitosan-coated ophthalmic lipid emulsion containing indomethacin in tear fluid
    • etal.
    • Yamaguchi M, etal. Mucoadhesive properties of chitosan-coated ophthalmic lipid emulsion containing indomethacin in tear fluid. Biol Pharm Bull 2009; 32: 1266-1271.
    • (2009) Biol Pharm Bull , vol.32 , pp. 1266-1271
    • Yamaguchi, M.1
  • 43
    • 84872339222 scopus 로고    scopus 로고
    • Development of O/W nanoemulsions for ophthalmic administration of timolol
    • etal.
    • Gallarate M, etal. Development of O/W nanoemulsions for ophthalmic administration of timolol. Int J Pharm 2013; 440: 126-134.
    • (2013) Int J Pharm , vol.440 , pp. 126-134
    • Gallarate, M.1
  • 44
    • 51849112416 scopus 로고    scopus 로고
    • Chitosan based nanocarriers for indomethacin ocular delivery
    • etal.
    • Badawi AA, etal. Chitosan based nanocarriers for indomethacin ocular delivery. Arch Pharm Res 2008; 31: 1040-1049.
    • (2008) Arch Pharm Res , vol.31 , pp. 1040-1049
    • Badawi, A.A.1
  • 45
    • 80053516790 scopus 로고    scopus 로고
    • Chitosan-coated ophthalmic submicro emulsion for pilocarpine nitrate
    • etal.:. [In Chinese].
    • Wei J, etal. Chitosan-coated ophthalmic submicro emulsion for pilocarpine nitrate. Acta Pharmacol Sin 2011; 46: 990-996. [In Chinese].
    • (2011) Acta Pharmacol Sin , vol.46 , pp. 990-996
    • Wei, J.1
  • 46
    • 75249101867 scopus 로고    scopus 로고
    • Chitosan-based nanostructures: A delivery platform for ocular therapeutics
    • etal.
    • De la Fuente M, etal. Chitosan-based nanostructures: a delivery platform for ocular therapeutics. Adv Drug Deliv Rev 2010; 62: 100-117.
    • (2010) Adv Drug Deliv Rev , vol.62 , pp. 100-117
    • De La Fuente, M.1
  • 47
    • 78651059860 scopus 로고    scopus 로고
    • Ocular ciprofloxacin hydrochloride mucoadhesive chitosan-coated liposomes
    • Abdelbary G,. Ocular ciprofloxacin hydrochloride mucoadhesive chitosan-coated liposomes. Pharm Dev Technol 2011; 16: 44-56.
    • (2011) Pharm Dev Technol , vol.16 , pp. 44-56
    • Abdelbary, G.1
  • 48
    • 84865027958 scopus 로고    scopus 로고
    • Cationic core-shell liponanoparticle for ocular drug gene delivery
    • etal.
    • Jiang M, etal. Cationic core-shell liponanoparticle for ocular drug gene delivery. Biomaterials 2012; 33: 7621-7630.
    • (2012) Biomaterials , vol.33 , pp. 7621-7630
    • Jiang, M.1
  • 49
    • 33845891058 scopus 로고    scopus 로고
    • Ocular drug delivery by liposome -chitosan nanoparticle complexes (LCS-NP)
    • etal.
    • Diebold Y, etal. Ocular drug delivery by liposome -chitosan nanoparticle complexes (LCS-NP). Biomaterials 2007; 28: 1553-1564.
    • (2007) Biomaterials , vol.28 , pp. 1553-1564
    • Diebold, Y.1
  • 50
    • 84855384628 scopus 로고    scopus 로고
    • Low molecular weight chitosan-coated liposomes for ocular drug delivery: In vitro and in vivo studies
    • etal.
    • Li N, etal. Low molecular weight chitosan-coated liposomes for ocular drug delivery: in vitro and in vivo studies. Drug Deliv 2012; 19: 28-35.
    • (2012) Drug Deliv , vol.19 , pp. 28-35
    • Li, N.1
  • 51
    • 64149088749 scopus 로고    scopus 로고
    • Topical use of coenzyme Q10-loaded liposomes coated with trimethyl chitosan: Tolerance, precorneal retention and anti-cataract effect
    • Zhang J, Wang S,. Topical use of coenzyme Q10-loaded liposomes coated with trimethyl chitosan: tolerance, precorneal retention and anti-cataract effect. Int J Pharm 2009; 372: 66-75.
    • (2009) Int J Pharm , vol.372 , pp. 66-75
    • Zhang, J.1    Wang, S.2
  • 52
    • 78650178421 scopus 로고    scopus 로고
    • Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system
    • etal.
    • Luo Q, etal. Nanostructured lipid carrier (NLC) coated with Chitosan Oligosaccharides and its potential use in ocular drug delivery system. Int J Pharm 2011; 403: 185-191.
    • (2011) Int J Pharm , vol.403 , pp. 185-191
    • Luo, Q.1
  • 53
    • 77949902171 scopus 로고    scopus 로고
    • Chitosan and its role in ocular therapeutics
    • etal.
    • Wadhwa S, etal. Chitosan and its role in ocular therapeutics. Mini Rev Med Chem 2009; 9: 1639-1647.
    • (2009) Mini Rev Med Chem , vol.9 , pp. 1639-1647
    • Wadhwa, S.1
  • 54
    • 80055017990 scopus 로고    scopus 로고
    • Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming gel
    • etal.
    • Gratieri T, etal. Enhancing and sustaining the topical ocular delivery of fluconazole using chitosan solution and poloxamer/chitosan in situ forming gel. Eur J Pharm Biopharm 2011; 79: 320-327.
    • (2011) Eur J Pharm Biopharm , vol.79 , pp. 320-327
    • Gratieri, T.1
  • 55
    • 34447309294 scopus 로고    scopus 로고
    • Poly(N-isopropylacrylamide)-chitosan as thermosensitive in situ gel-forming system for ocular drug delivery
    • etal.
    • Cao Y, etal. Poly(N-isopropylacrylamide)-chitosan as thermosensitive in situ gel-forming system for ocular drug delivery. J Control Release 2007; 120: 186-194.
    • (2007) J Control Release , vol.120 , pp. 186-194
    • Cao, Y.1
  • 56
    • 77952957786 scopus 로고    scopus 로고
    • A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery
    • etal.
    • Gratieri T, etal. A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery. Eur J Pharm Biopharm 2010; 75: 186-193.
    • (2010) Eur J Pharm Biopharm , vol.75 , pp. 186-193
    • Gratieri, T.1
  • 57
    • 78650227405 scopus 로고    scopus 로고
    • Carbopol/chitosan based pH triggered in situ gelling system for ocular delivery of timolol maleate
    • Gupta S, Vyas SP,. Carbopol/chitosan based pH triggered in situ gelling system for ocular delivery of timolol maleate. Sci Pharm 2010; 78: 959-976.
    • (2010) Sci Pharm , vol.78 , pp. 959-976
    • Gupta, S.1    Vyas, S.P.2
  • 58
    • 84861600703 scopus 로고    scopus 로고
    • Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies
    • etal.
    • Bhatta RS, etal. Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: in vitro and pharmacokinetics studies. Int J Pharm 2012; 432: 105-112.
    • (2012) Int J Pharm , vol.432 , pp. 105-112
    • Bhatta, R.S.1
  • 59
    • 79958014984 scopus 로고    scopus 로고
    • Chitosan/sulfobutylether-β-cyclodextrin nanoparticles as a potential approach for ocular drug delivery
    • etal.
    • Mahmoud AA, etal. Chitosan/sulfobutylether-β-cyclodextrin nanoparticles as a potential approach for ocular drug delivery. Int J Pharm 2011; 413: 229-236.
    • (2011) Int J Pharm , vol.413 , pp. 229-236
    • Mahmoud, A.A.1
  • 60
    • 79551479125 scopus 로고    scopus 로고
    • Chitosan nanoparticles of 5-fluorouracil for ophthalmic delivery: Characterization, in-vitro and in-vivo study
    • etal.
    • Nagarwal RC, etal. Chitosan nanoparticles of 5-fluorouracil for ophthalmic delivery: characterization, in-vitro and in-vivo study. Chem Pharm Bull 2011; 59: 272-278.
    • (2011) Chem Pharm Bull , vol.59 , pp. 272-278
    • Nagarwal, R.C.1
  • 61
    • 78649442663 scopus 로고    scopus 로고
    • Microscopic and spectroscopic evaluation of novel PLGA-chitosan Nanoplexes as an ocular delivery system
    • etal.
    • Jain GK, etal. Microscopic and spectroscopic evaluation of novel PLGA-chitosan Nanoplexes as an ocular delivery system. Colloids Surf B Biointerfaces 2011; 82: 397-403.
    • (2011) Colloids Surf B Biointerfaces , vol.82 , pp. 397-403
    • Jain, G.K.1
  • 62
    • 79953016653 scopus 로고    scopus 로고
    • Chitosan coated PLA nanoparticles for ophthalmic delivery: Characterization, in-vitro and in-vivo study in rabbit eye
    • etal.
    • Nagarwal RC, etal. Chitosan coated PLA nanoparticles for ophthalmic delivery: characterization, in-vitro and in-vivo study in rabbit eye. J Biomed Nanotechnol 2010; 6: 648-657.
    • (2010) J Biomed Nanotechnol , vol.6 , pp. 648-657
    • Nagarwal, R.C.1
  • 63
    • 79551717015 scopus 로고    scopus 로고
    • Intracellular trafficking of hyaluronic acid-chitosan oligomer-based nanoparticles in cultured human ocular surface cells
    • etal.
    • Contreras-Ruiz L, etal. Intracellular trafficking of hyaluronic acid-chitosan oligomer-based nanoparticles in cultured human ocular surface cells. Mol Vis 2011; 17: 279-290.
    • (2011) Mol Vis , vol.17 , pp. 279-290
    • Contreras-Ruiz, L.1
  • 64
    • 0030279709 scopus 로고    scopus 로고
    • Improved ocular bioavailability of indomethacin by novel ocular drug carriers
    • etal.
    • Calvo P, etal. Improved ocular bioavailability of indomethacin by novel ocular drug carriers. J Pharm Pharmacol 1996; 48: 1147-1152.
    • (1996) J Pharm Pharmacol , vol.48 , pp. 1147-1152
    • Calvo, P.1
  • 65
    • 0042834363 scopus 로고    scopus 로고
    • The effect of a PEG versus a chitosan coating on the interaction of drug colloidal carriers with the ocular mucosa
    • etal.
    • De Campos AM, etal. The effect of a PEG versus a chitosan coating on the interaction of drug colloidal carriers with the ocular mucosa. Eur J Pharm Sci 2003; 20: 73-81.
    • (2003) Eur J Pharm Sci , vol.20 , pp. 73-81
    • De Campos, A.M.1
  • 66
    • 26644437438 scopus 로고    scopus 로고
    • The use of mucoadhesive polymers in ocular drug delivery
    • Ludwing A,. The use of mucoadhesive polymers in ocular drug delivery. Adv Drug Deliv Rev 2005; 57: 1595-1693.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 1595-1693
    • Ludwing, A.1
  • 67
    • 84866499684 scopus 로고    scopus 로고
    • Chitosan coated sodium alginate-chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye
    • etal.
    • Nagarwal RC, etal. Chitosan coated sodium alginate-chitosan nanoparticles loaded with 5-FU for ocular delivery: in vitro characterization and in vivo study in rabbit eye. Eur J Pharm Sci 2012; 47: 678-685.
    • (2012) Eur J Pharm Sci , vol.47 , pp. 678-685
    • Nagarwal, R.C.1
  • 68
    • 0035850231 scopus 로고    scopus 로고
    • Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system
    • etal.
    • Srividya B, etal. Sustained ophthalmic delivery of ofloxacin from a pH triggered in situ gelling system. J Control Release 2001; 73: 205-211.
    • (2001) J Control Release , vol.73 , pp. 205-211
    • Srividya, B.1
  • 69
    • 84892932735 scopus 로고    scopus 로고
    • Formulation and evaluation of an in situ gel-forming ophthalmic formulation of moxifloxacin hydrochloride
    • etal.
    • Mandal S, etal. Formulation and evaluation of an in situ gel-forming ophthalmic formulation of moxifloxacin hydrochloride. Int J Pharm Investig 2012; 2: 78-82.
    • (2012) Int J Pharm Investig , vol.2 , pp. 78-82
    • Mandal, S.1
  • 70
    • 79957897806 scopus 로고    scopus 로고
    • Extended release of high molecular weight hydroxypropyl methylcellulose from molecularly imprinted, extended wear silicone hydrogel contact lenses
    • etal.
    • White CJ, etal. Extended release of high molecular weight hydroxypropyl methylcellulose from molecularly imprinted, extended wear silicone hydrogel contact lenses. Biomaterials 2011; 32: 5698-5705.
    • (2011) Biomaterials , vol.32 , pp. 5698-5705
    • White, C.J.1
  • 71
    • 0001985178 scopus 로고
    • Positively charged submicron emulsions - A new type of colloidal drug carrier
    • etal.
    • Elbaz E, etal. Positively charged submicron emulsions-a new type of colloidal drug carrier. Int J Pharm 1993; 96: R1-R6.
    • (1993) Int J Pharm , vol.96
    • Elbaz, E.1
  • 72
    • 0028763449 scopus 로고
    • Emulsions as drug carriers for ophthalmic use
    • Muchtar S, Benita S,. Emulsions as drug carriers for ophthalmic use. Colloids Surf A 1994; 91: 181-190.
    • (1994) Colloids Surf A , vol.91 , pp. 181-190
    • Muchtar, S.1    Benita, S.2
  • 73
    • 0029940928 scopus 로고    scopus 로고
    • Comparative in vitro evaluation of several colloidal systems, nanoparticles, nanocapsules, and nanoemulsions, as ocular drug carriers
    • etal.
    • Calvo P, etal. Comparative in vitro evaluation of several colloidal systems, nanoparticles, nanocapsules, and nanoemulsions, as ocular drug carriers. J Pharm Sci 1996; 85: 530-536.
    • (1996) J Pharm Sci , vol.85 , pp. 530-536
    • Calvo, P.1
  • 74
    • 0032929942 scopus 로고    scopus 로고
    • Submicron cationic emulsions as a new delivery system for oligonucleotides
    • etal.
    • Teixeira H, etal. Submicron cationic emulsions as a new delivery system for oligonucleotides. Pharm Res 1999; 16: 30-36.
    • (1999) Pharm Res , vol.16 , pp. 30-36
    • Teixeira, H.1
  • 75
    • 61349192199 scopus 로고    scopus 로고
    • Lecithin based nanoemulsions: A comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation
    • etal.
    • Hoeller S, etal. Lecithin based nanoemulsions: a comparative study of the influence of non-ionic surfactants and the cationic phytosphingosine on physicochemical behaviour and skin permeation. Int J Pharm 2009; 370: 181-186.
    • (2009) Int J Pharm , vol.370 , pp. 181-186
    • Hoeller, S.1
  • 76
    • 41349106751 scopus 로고    scopus 로고
    • Diclofenac sodium delivery to the eye: In vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct
    • etal.
    • Attama AA, etal. Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct. Int J Pharm 2008; 355: 307-313.
    • (2008) Int J Pharm , vol.355 , pp. 307-313
    • Attama, A.A.1
  • 77
    • 84872458094 scopus 로고    scopus 로고
    • Study of ocular drug delivery system using drug-loaded liposomes
    • Jain RL, Shastri JP,. Study of ocular drug delivery system using drug-loaded liposomes. Int J Pharm Investig 2011; 1: 35-41.
    • (2011) Int J Pharm Investig , vol.1 , pp. 35-41
    • Jain, R.L.1    Shastri, J.P.2
  • 78
    • 77954290414 scopus 로고    scopus 로고
    • Ion- and pH-activated novel in-situ gel system for sustained ocular drug delivery
    • etal.
    • Gupta H, etal. Ion- and pH-activated novel in-situ gel system for sustained ocular drug delivery. J Drug Target 2010; 18: 499-505.
    • (2010) J Drug Target , vol.18 , pp. 499-505
    • Gupta, H.1
  • 79
    • 57349134515 scopus 로고    scopus 로고
    • PLGA nanospheres for the ocular delivery of flurbiprofen: Drug release and interactions
    • etal.
    • Vega E, etal. PLGA nanospheres for the ocular delivery of flurbiprofen: drug release and interactions. J Pharm Sci 2008; 97: 5306-5317.
    • (2008) J Pharm Sci , vol.97 , pp. 5306-5317
    • Vega, E.1
  • 80
    • 1842450748 scopus 로고    scopus 로고
    • The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers
    • etal.
    • Qaddoumi MG, etal. The characteristics and mechanisms of uptake of PLGA nanoparticles in rabbit conjunctival epithelial cell layers. Pharm Res 2004; 21: 641-648.
    • (2004) Pharm Res , vol.21 , pp. 641-648
    • Qaddoumi, M.G.1
  • 81
    • 79957490620 scopus 로고    scopus 로고
    • Development and characterization of Cyclosporine A loaded nanoparticles for ocular drug delivery: Cellular toxicity, uptake and kinetic studies
    • etal.
    • Aksungur P, etal. Development and characterization of Cyclosporine A loaded nanoparticles for ocular drug delivery: cellular toxicity, uptake and kinetic studies. J Control Release 2011; 151: 286-294.
    • (2011) J Control Release , vol.151 , pp. 286-294
    • Aksungur, P.1
  • 82
    • 34248571833 scopus 로고    scopus 로고
    • Development of a poloxamer analogs/carbopol-based in situ gelling and mucoadhesive ophthalmic delivery system for puerarin
    • etal.
    • Qi H, etal. Development of a poloxamer analogs/carbopol-based in situ gelling and mucoadhesive ophthalmic delivery system for puerarin. Int J Pharm 2007; 337: 178-187.
    • (2007) Int J Pharm , vol.337 , pp. 178-187
    • Qi, H.1
  • 83
    • 46949093372 scopus 로고    scopus 로고
    • Ocular poloxamer-based ciprofloxacin hydrochloride in situ forming gels
    • etal.
    • Mansour M, etal. Ocular poloxamer-based ciprofloxacin hydrochloride in situ forming gels. Drug Dev Ind Pharm 2008; 4: 744-752.
    • (2008) Drug Dev Ind Pharm , vol.4 , pp. 744-752
    • Mansour, M.1
  • 84
    • 50349102596 scopus 로고    scopus 로고
    • A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery: Rheological, mucoadhesive and in vitro release properties
    • etal.
    • Mayo L, etal. A novel poloxamers/hyaluronic acid in situ forming hydrogel for drug delivery: rheological, mucoadhesive and in vitro release properties. Eur J Pharm Biopharm 2008; 70: 199-206.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 199-206
    • Mayo, L.1
  • 85
    • 84899486513 scopus 로고    scopus 로고
    • Studies on poloxamer based mucoadhesive insitu ophthalmic hydrogel of moxifloxacin HCL
    • etal.
    • Shastri DH, etal. Studies on poloxamer based mucoadhesive insitu ophthalmic hydrogel of moxifloxacin HCL. Curr Drug Deliv 2010; 3: 77-86.
    • (2010) Curr Drug Deliv , vol.3 , pp. 77-86
    • Shastri, D.H.1
  • 86
    • 48949120123 scopus 로고    scopus 로고
    • Physical characterization and in vivo evaluation of poloxamer-based DNA vaccine formulations
    • Hartikka J,. Physical characterization and in vivo evaluation of poloxamer-based DNA vaccine formulations. J Gene Med 2008; 10: 770-782.
    • (2008) J Gene Med , vol.10 , pp. 770-782
    • Hartikka, J.1
  • 87
    • 0027340111 scopus 로고
    • Poly(epsilon-caprolactone) nanocapsules in carteolol ophthalmic delivery
    • etal.
    • Marchal-Heussler L, etal. Poly(epsilon-caprolactone) nanocapsules in carteolol ophthalmic delivery. Pharm Res 1993; 10: 386-390.
    • (1993) Pharm Res , vol.10 , pp. 386-390
    • Marchal-Heussler, L.1
  • 88
    • 11844250522 scopus 로고    scopus 로고
    • Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide
    • Vandamme TF, Brobeck L,. Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide. J Control Release 2005; 102: 23-38.
    • (2005) J Control Release , vol.102 , pp. 23-38
    • Vandamme, T.F.1    Brobeck, L.2
  • 89
    • 77956104883 scopus 로고    scopus 로고
    • Effect of poly(amidoamine) dendrimers on corneal penetration of puerarin
    • etal.
    • Yao WJ, etal. Effect of poly(amidoamine) dendrimers on corneal penetration of puerarin. Biol Pharm Bull 2010; 33: 1371-1377.
    • (2010) Biol Pharm Bull , vol.33 , pp. 1371-1377
    • Yao, W.J.1
  • 90
    • 84860389756 scopus 로고    scopus 로고
    • Determination of puerarin in rabbit aqueous humor by liquid chromatography tandem mass spectrometry using microdialysis sampling after topical administration of puerarin PAMAM dendrimercomplex
    • etal.
    • Wang WY, etal. Determination of puerarin in rabbit aqueous humor by liquid chromatography tandem mass spectrometry using microdialysis sampling after topical administration of puerarin PAMAM dendrimercomplex. J Pharm Biomed Anal 2011; 56: 825-829.
    • (2011) J Pharm Biomed Anal , vol.56 , pp. 825-829
    • Wang, W.Y.1
  • 91
    • 59349116903 scopus 로고    scopus 로고
    • Knocking down barriers: Advances in siRNA delivery
    • etal.
    • Whitehead KA, etal. Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov 2009; 8: 129-138.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 129-138
    • Whitehead, K.A.1
  • 92
    • 0021999774 scopus 로고
    • Ocular disposition of poly-hexyl-2-cyano(3-14C) acrylate nanoparticles in the albino rabbit
    • etal.
    • Wood RW, etal. Ocular disposition of poly-hexyl-2-cyano(3-14C) acrylate nanoparticles in the albino rabbit. Int J Pharm 1985; 23: 175-183.
    • (1985) Int J Pharm , vol.23 , pp. 175-183
    • Wood, R.W.1
  • 93
    • 84875209383 scopus 로고    scopus 로고
    • Retinal drug delivery using eyedrop preparations of poly-L-lysine- modified liposomes
    • etal.
    • Sasaki H, etal. Retinal drug delivery using eyedrop preparations of poly-L-lysine-modified liposomes. Eur J Pharm Biopharm 2013; 83: 364-369.
    • (2013) Eur J Pharm Biopharm , vol.83 , pp. 364-369
    • Sasaki, H.1
  • 94
    • 0037020490 scopus 로고    scopus 로고
    • Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid
    • Hiratani H, Alvarez-Lorenzo C,. Timolol uptake and release by imprinted soft contact lenses made of N,N-diethylacrylamide and methacrylic acid. J Control Release 2002; 83: 223-230.
    • (2002) J Control Release , vol.83 , pp. 223-230
    • Hiratani, H.1    Alvarez-Lorenzo, C.2
  • 95
    • 84867002915 scopus 로고    scopus 로고
    • A comparative study of a preservative-free latanoprost cationic emulsion (catioprost) and a BAK-preserved latanoprost solution in animal models
    • etal.
    • Daull P, etal. A comparative study of a preservative-free latanoprost cationic emulsion (catioprost) and a BAK-preserved latanoprost solution in animal models. J Ocul Pharmacol Ther 2012; 28: 515-523.
    • (2012) J Ocul Pharmacol Ther , vol.28 , pp. 515-523
    • Daull, P.1
  • 96
    • 38949172038 scopus 로고    scopus 로고
    • Reduction of quaternary ammonium-induced ocular surface toxicity by emulsions: An in vivo study in rabbits
    • etal.
    • Liang H, etal. Reduction of quaternary ammonium-induced ocular surface toxicity by emulsions: an in vivo study in rabbits. Mol Vis 2008; 14: 204-216.
    • (2008) Mol Vis , vol.14 , pp. 204-216
    • Liang, H.1
  • 97
    • 0034633968 scopus 로고    scopus 로고
    • Application of in vivo confocal microscopy to the objective evaluation of ocular irritation induced by surfactants
    • etal.
    • Furrer P, etal. Application of in vivo confocal microscopy to the objective evaluation of ocular irritation induced by surfactants. Int J Pharm 2000; 207: 89-98.
    • (2000) Int J Pharm , vol.207 , pp. 89-98
    • Furrer, P.1
  • 98
    • 79955959772 scopus 로고    scopus 로고
    • Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 1: Physicochemical characterisation and in vitro release
    • etal.
    • Rupenthal ID, etal. Comparison of ion-activated in situ gelling systems for ocular drug delivery. Part 1: physicochemical characterisation and in vitro release. Int J Pharm 2011; 411: 69-77.
    • (2011) Int J Pharm , vol.411 , pp. 69-77
    • Rupenthal, I.D.1
  • 99
    • 33646366411 scopus 로고    scopus 로고
    • Study of an alginate/HPMC-based in situ gelling ophthalmic delivery system for gatifloxacin
    • etal.
    • Liu Z, etal. Study of an alginate/HPMC-based in situ gelling ophthalmic delivery system for gatifloxacin. Int J Pharm 2006; 315: 12-17.
    • (2006) Int J Pharm , vol.315 , pp. 12-17
    • Liu, Z.1
  • 100
    • 77954819693 scopus 로고    scopus 로고
    • In situ gelling gelrite/alginate formulations as vehicles for ophthalmic drug delivery
    • etal.
    • Liu Y, etal. In situ gelling gelrite/alginate formulations as vehicles for ophthalmic drug delivery. AAPS PharmSciTech 2010; 11: 610-620.
    • (2010) AAPS PharmSciTech , vol.11 , pp. 610-620
    • Liu, Y.1
  • 102
    • 1842711882 scopus 로고    scopus 로고
    • Formation and stability of nano-emulsions
    • etal.
    • Tadros T, etal. Formation and stability of nano-emulsions. Adv Colloid Interface Sci 2004; 108-109: 303-318.
    • (2004) Adv Colloid Interface Sci , pp. 303-318
    • Tadros, T.1
  • 103
    • 78650539714 scopus 로고    scopus 로고
    • Self-nanoemulsifying drug delivery systems: Formulation insights, applications and advances
    • etal.
    • Date AA, etal. Self-nanoemulsifying drug delivery systems: formulation insights, applications and advances. Nanomedicine 2010; 5: 1595-1616.
    • (2010) Nanomedicine , vol.5 , pp. 1595-1616
    • Date, A.A.1
  • 104
    • 10044228076 scopus 로고    scopus 로고
    • Nano-emulsions: Formation, properties, and applications
    • etal. Mittal K.L. Dinesh O.S. eds. New York: Marcel Dekker.
    • Solans C, etal. Nano-emulsions: formation, properties, and applications. In:, Mittal KL, Dinesh OS, eds. Adsorption and Aggregation of Surfactants in Solution. New York: Marcel Dekker, 2003: 525-554.
    • (2003) Adsorption and Aggregation of Surfactants in Solution , pp. 525-554
    • Solans, C.1
  • 105
    • 44749087481 scopus 로고    scopus 로고
    • Design and production of nanoparticles formulated from nano-emulsion templates - A review
    • etal.
    • Anton N, etal. Design and production of nanoparticles formulated from nano-emulsion templates-a review. J Control Release 2008; 128: 185-199.
    • (2008) J Control Release , vol.128 , pp. 185-199
    • Anton, N.1
  • 106
    • 0141607190 scopus 로고    scopus 로고
    • A study of the relation between bicontinuous microemulsions and oil/water nano-emulsion formation
    • etal.
    • Morales D, etal. A study of the relation between bicontinuous microemulsions and oil/water nano-emulsion formation. Langmuir 2003; 19: 7196-7200.
    • (2003) Langmuir , vol.19 , pp. 7196-7200
    • Morales, D.1
  • 107
    • 0026687335 scopus 로고
    • A submicron emulsion as ocular vehicle for delta-S-tetrahydro-cannabinol: Effect on intraocular pressure in rabbits
    • etal.
    • Muchtar S, etal. A submicron emulsion as ocular vehicle for delta-S-tetrahydro-cannabinol: effect on intraocular pressure in rabbits. Ophthalmic Res 1992; 24: 142-149.
    • (1992) Ophthalmic Res , vol.24 , pp. 142-149
    • Muchtar, S.1
  • 108
    • 0035247884 scopus 로고    scopus 로고
    • Selective extraction of phosphatidylcholine from lecithin by supercritical carbon dioxide/ethanol mixture
    • etal.
    • Teberikler L, etal. Selective extraction of phosphatidylcholine from lecithin by supercritical carbon dioxide/ethanol mixture. J Am Oil Chem Soc 2001; 78: 115-120.
    • (2001) J Am Oil Chem Soc , vol.78 , pp. 115-120
    • Teberikler, L.1
  • 109
    • 0036027683 scopus 로고    scopus 로고
    • Cholesterol interactions with phospholipids in membranes
    • etal.
    • Ohvo-Rekila H, etal. Cholesterol interactions with phospholipids in membranes. Prog Lipid Res 2002; 41: 66-97.
    • (2002) Prog Lipid Res , vol.41 , pp. 66-97
    • Ohvo-Rekila, H.1
  • 110
    • 0034018676 scopus 로고    scopus 로고
    • A submicron emulsion of HU-211, a synthetic cannabinoid, reduces intraocular pressure in rabbits
    • Naveh N,. A submicron emulsion of HU-211, a synthetic cannabinoid, reduces intraocular pressure in rabbits. Graefes Arch Clin Exp Ophthalmol 2000; 238: 334-338.
    • (2000) Graefes Arch Clin Exp Ophthalmol , vol.238 , pp. 334-338
    • Naveh, N.1
  • 111
    • 0030987752 scopus 로고    scopus 로고
    • Development of positively charged colloidal drug carriers: Chitosan-coated polyester nanocapsules and submicron-emulsions
    • etal.
    • Calvo P, etal. Development of positively charged colloidal drug carriers: chitosan-coated polyester nanocapsules and submicron-emulsions. Colloid Polym Sci 1997; 275: 46-53.
    • (1997) Colloid Polym Sci , vol.275 , pp. 46-53
    • Calvo, P.1
  • 112
    • 68149132922 scopus 로고    scopus 로고
    • Comparative toxicity of preservatives on immortalized corneal and conjunctival epithelial cells
    • etal.
    • Epstein SP, etal. Comparative toxicity of preservatives on immortalized corneal and conjunctival epithelial cells. J Ocul Pharmacol Ther 2009; 25: 113-119.
    • (2009) J Ocul Pharmacol Ther , vol.25 , pp. 113-119
    • Epstein, S.P.1
  • 113
    • 84899487332 scopus 로고    scopus 로고
    • A phase 2, randomized study evaluating the safety and efficacy of Catioprost® (unpreserved latanoprost 0.005% emulsion) compared to Travatan Z® in subjects with glaucoma and ocular surface disease
    • etal.
    • Ismail D, etal. A phase 2, randomized study evaluating the safety and efficacy of Catioprost® (unpreserved latanoprost 0.005% emulsion) compared to Travatan Z® in subjects with glaucoma and ocular surface disease. Acta Ophthalmol 2011; 89: 248s.
    • (2011) Acta Ophthalmol , vol.89
    • Ismail, D.1
  • 114
    • 79956265517 scopus 로고    scopus 로고
    • Liposome: A review of manufacturing techniques and targeting strategies
    • etal.
    • Maherani B, etal. Liposome: a review of manufacturing techniques and targeting strategies. Curr Nanosci 2011; 7: 436-452.
    • (2011) Curr Nanosci , vol.7 , pp. 436-452
    • Maherani, B.1
  • 115
    • 14844336918 scopus 로고    scopus 로고
    • Applications of liposomes in ophthalmology
    • etal.
    • Ebrahim S, etal. Applications of liposomes in ophthalmology. Surv Ophthalmol 2005; 50: 167-182.
    • (2005) Surv Ophthalmol , vol.50 , pp. 167-182
    • Ebrahim, S.1
  • 116
    • 0346787779 scopus 로고    scopus 로고
    • Vesicular systems in ocular drug delivery: An overview
    • etal.
    • Kaur IP, etal. Vesicular systems in ocular drug delivery: an overview. Int J Pharm 2004; 269: 1-14.
    • (2004) Int J Pharm , vol.269 , pp. 1-14
    • Kaur, I.P.1
  • 117
    • 84861031974 scopus 로고    scopus 로고
    • Liposomes for intravitreal drug delivery: A state of the art
    • Bochot A, Fattal E,. Liposomes for intravitreal drug delivery: a state of the art. J Control Release 2012; 161: 628-634.
    • (2012) J Control Release , vol.161 , pp. 628-634
    • Bochot, A.1    Fattal, E.2
  • 118
    • 0021928971 scopus 로고
    • Ocular drug bioavailability from topically applied liposomes
    • etal.
    • Lee VHL, etal. Ocular drug bioavailability from topically applied liposomes. Surv Ophthalmol 1985; 29: 335-348.
    • (1985) Surv Ophthalmol , vol.29 , pp. 335-348
    • Lee, V.H.L.1
  • 119
    • 0029347460 scopus 로고
    • Liposome ocular delivery systems
    • Meisner D, Mezeib M,. Liposome ocular delivery systems. Adv Drug Deliv Rev 1995; 16: 75-93.
    • (1995) Adv Drug Deliv Rev , vol.16 , pp. 75-93
    • Meisner, D.1    Mezeib, M.2
  • 120
    • 0025107666 scopus 로고
    • Liposomes as drug delivery systems to the lung
    • Kellaway IW, Farr SJ,. Liposomes as drug delivery systems to the lung. Adv Drug Deliv Rev 1990; 5: 49-16.
    • (1990) Adv Drug Deliv Rev , vol.5 , pp. 49-16
    • Kellaway, I.W.1    Farr, S.J.2
  • 121
    • 44149127417 scopus 로고    scopus 로고
    • Liposomes in ultrasonic drug and gene delivery
    • Huang SL,. Liposomes in ultrasonic drug and gene delivery. Adv Drug Deliv Rev 2008; 60: 1167-1176.
    • (2008) Adv Drug Deliv Rev , vol.60 , pp. 1167-1176
    • Huang, S.L.1
  • 122
    • 0025047626 scopus 로고
    • Liposomes as a topical drug delivery system
    • Egbaria K, Weiner N,. Liposomes as a topical drug delivery system. Adv Drug Deliv Rev 1990; 5: 287-300.
    • (1990) Adv Drug Deliv Rev , vol.5 , pp. 287-300
    • Egbaria, K.1    Weiner, N.2
  • 123
    • 0030795298 scopus 로고    scopus 로고
    • Liposomes in drug delivery: Progress and limitations
    • Sharma A, Sharma US,. Liposomes in drug delivery: progress and limitations. Int J Pharm 1997; 154: 123-140.
    • (1997) Int J Pharm , vol.154 , pp. 123-140
    • Sharma, A.1    Sharma, U.S.2
  • 124
    • 0343376089 scopus 로고    scopus 로고
    • Supramolecular lipidic drug delivery systems: From laboratory to clinic A review of the recently introduced commercial liposomal and lipid-based formulations of amphotericin B
    • Hillery AM,. Supramolecular lipidic drug delivery systems: from laboratory to clinic A review of the recently introduced commercial liposomal and lipid-based formulations of amphotericin B. Adv Drug Deliv Rev 1997; 24: 345-363.
    • (1997) Adv Drug Deliv Rev , vol.24 , pp. 345-363
    • Hillery, A.M.1
  • 125
    • 70350292588 scopus 로고    scopus 로고
    • Liposomes and nanoparticles: Nanosized vehicles for drug delivery in cancer
    • etal.
    • Malam Y, etal. Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer. Trends Pharmacol Sci 2009; 30: 592-599.
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 592-599
    • Malam, Y.1
  • 126
    • 84873252557 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: From concept to clinical application
    • Allen TM, Cullis PR,. Liposomal drug delivery systems: from concept to clinical application. Adv Drug Deliv Rev 2012; 65: 36-48.
    • (2012) Adv Drug Deliv Rev , vol.65 , pp. 36-48
    • Allen, T.M.1    Cullis, P.R.2
  • 127
    • 0035981054 scopus 로고    scopus 로고
    • Thermosensitive polymer-modified liposomes
    • Kono K,. Thermosensitive polymer-modified liposomes. Adv Drug Deliv Rev 2001; 53: 307-319.
    • (2001) Adv Drug Deliv Rev , vol.53 , pp. 307-319
    • Kono, K.1
  • 128
    • 0033166573 scopus 로고    scopus 로고
    • Liposomes, micelles and microemulsions as new delivery systems for cytotoxic alkaloids
    • Cortesi R, Nastruzzi C,. Liposomes, micelles and microemulsions as new delivery systems for cytotoxic alkaloids. Pharm Sci Technolo Today 1999; 2: 288-298.
    • (1999) Pharm Sci Technolo Today , vol.2 , pp. 288-298
    • Cortesi, R.1    Nastruzzi, C.2
  • 129
    • 0021717424 scopus 로고
    • Ophthalmic drug delivery systems
    • Shell JW,. Ophthalmic drug delivery systems. Surv Ophthalmol 1984; 29: 117-128.
    • (1984) Surv Ophthalmol , vol.29 , pp. 117-128
    • Shell, J.W.1
  • 130
    • 84873942340 scopus 로고    scopus 로고
    • Liposomes and nanotechnology in drug development: Focus on ocular targets
    • etal.
    • Honda M, etal. Liposomes and nanotechnology in drug development: focus on ocular targets. Int J Nanomedicine 2013; 8: 495-503.
    • (2013) Int J Nanomedicine , vol.8 , pp. 495-503
    • Honda, M.1
  • 131
    • 0019382912 scopus 로고
    • Iodoxuridine-liposome therapy for herpes simplex keratitis
    • etal.
    • Smolin G, etal. Iodoxuridine-liposome therapy for herpes simplex keratitis. Am J Ophthalmol 1981; 91: 220-226.
    • (1981) Am J Ophthalmol , vol.91 , pp. 220-226
    • Smolin, G.1
  • 132
    • 0031438323 scopus 로고    scopus 로고
    • Preparation and evaluation of acetazolamide liposomes as an ocular delivery system
    • El-Gazayerly ON, Hikal AH,. Preparation and evaluation of acetazolamide liposomes as an ocular delivery system. Int J Pharm 1997; 158: 121-127.
    • (1997) Int J Pharm , vol.158 , pp. 121-127
    • El-Gazayerly, O.N.1    Hikal, A.H.2
  • 133
    • 34648828605 scopus 로고    scopus 로고
    • Liposomal amphotericin B eye drops to treat fungal keratitis: Physico-chemical and formulation stability
    • etal.
    • Morand K, etal. Liposomal amphotericin B eye drops to treat fungal keratitis: physico-chemical and formulation stability. Int J Pharm 2007; 344: 150-153.
    • (2007) Int J Pharm , vol.344 , pp. 150-153
    • Morand, K.1
  • 134
    • 0033977825 scopus 로고    scopus 로고
    • Acyclovir-containing liposomes for potential ocular delivery Corneal penetration and absorption
    • etal.
    • Law SL, etal. Acyclovir-containing liposomes for potential ocular delivery Corneal penetration and absorption. J Control Release 2000; 63: 135-140.
    • (2000) J Control Release , vol.63 , pp. 135-140
    • Law, S.L.1
  • 135
    • 77950370013 scopus 로고    scopus 로고
    • Effect of a liposomal spray on the pre-ocular tear film
    • etal.
    • Craig JP, etal. Effect of a liposomal spray on the pre-ocular tear film. Cont Lens Anterior Eye 2012; 33: 83-87.
    • (2012) Cont Lens Anterior Eye , vol.33 , pp. 83-87
    • Craig, J.P.1
  • 136
    • 0029968193 scopus 로고    scopus 로고
    • Gene transfer to the retina of rat by liposome eye drops
    • etal.
    • Matsuo T, etal. Gene transfer to the retina of rat by liposome eye drops. Biochem Biophys Res Commun 1996; 219: 947-950.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 947-950
    • Matsuo, T.1
  • 137
    • 0026658572 scopus 로고
    • Fibrin-enmeshed tobramycin liposomes: Single application topical therapy of Pseudomonas keratitis
    • etal.
    • Frucht-Perry J, etal. Fibrin-enmeshed tobramycin liposomes: single application topical therapy of Pseudomonas keratitis. Cornea 1992; 11: 393-397.
    • (1992) Cornea , vol.11 , pp. 393-397
    • Frucht-Perry, J.1
  • 138
    • 69249222639 scopus 로고    scopus 로고
    • New formulation of vasoactive intestinal peptide using liposomes in hyaluronic acid gel for uveitis
    • etal.
    • Lajavardi L, etal. New formulation of vasoactive intestinal peptide using liposomes in hyaluronic acid gel for uveitis. J Control Release 2009; 139: 22-30.
    • (2009) J Control Release , vol.139 , pp. 22-30
    • Lajavardi, L.1
  • 139
    • 0020695633 scopus 로고
    • Effects of topically applied liposomes on disposition of epinephrine and inulin in the albino rabbit eye
    • etal.
    • Stratford RE, etal. Effects of topically applied liposomes on disposition of epinephrine and inulin in the albino rabbit eye. Int J Pharm 1983; 13: 263-272.
    • (1983) Int J Pharm , vol.13 , pp. 263-272
    • Stratford, R.E.1
  • 140
    • 84866354364 scopus 로고    scopus 로고
    • Effect of three different liposomal eye sprays on ocular comfort and tear film
    • etal.
    • Pult H, etal. Effect of three different liposomal eye sprays on ocular comfort and tear film. Cont Lens Anterior Eye 2012; 35: 203-207.
    • (2012) Cont Lens Anterior Eye , vol.35 , pp. 203-207
    • Pult, H.1
  • 141
    • 33745002935 scopus 로고    scopus 로고
    • Cationic liposomes as potential carriers for ocular administration of peptides with anti-herpetic activity
    • etal.
    • Cortesi R, etal. Cationic liposomes as potential carriers for ocular administration of peptides with anti-herpetic activity. Int J Pharm 2006; 317: 90-100.
    • (2006) Int J Pharm , vol.317 , pp. 90-100
    • Cortesi, R.1
  • 142
    • 1842527035 scopus 로고    scopus 로고
    • Comparison of liposome-encapsulated acyclovir with acyclovir ointment: Ocular pharmacokinectics in rabbits
    • etal.
    • Chetoni P, etal. Comparison of liposome-encapsulated acyclovir with acyclovir ointment: ocular pharmacokinectics in rabbits. J Ocul Pharmacol Ther 2004; 20: 169-177.
    • (2004) J Ocul Pharmacol Ther , vol.20 , pp. 169-177
    • Chetoni, P.1
  • 143
    • 0021367596 scopus 로고
    • Precorneal factors influencing the ocular distribution of topically applied liposomal inulin
    • etal.
    • Lee VH, etal. Precorneal factors influencing the ocular distribution of topically applied liposomal inulin. Curr Eye Res 1984; 3: 585-591.
    • (1984) Curr Eye Res , vol.3 , pp. 585-591
    • Lee, V.H.1
  • 144
    • 0019915456 scopus 로고
    • Lectin-mediated attachment of liposomes to cornea: Influence on transcorneal drug flux
    • etal.
    • Schaeffer HE, etal. Lectin-mediated attachment of liposomes to cornea: influence on transcorneal drug flux. Invest Ophthalmol Vis Sci 1982; 23: 530-533.
    • (1982) Invest Ophthalmol Vis Sci , vol.23 , pp. 530-533
    • Schaeffer, H.E.1
  • 145
    • 0025280716 scopus 로고
    • Retention of topical liposomal formulations on the cornea
    • McCalden TA, Levy M,. Retention of topical liposomal formulations on the cornea. Experientia 1990; 46: 713-715.
    • (1990) Experientia , vol.46 , pp. 713-715
    • McCalden, T.A.1    Levy, M.2
  • 146
    • 0021275457 scopus 로고
    • The effects of charge and size on the interaction of unilamellar liposomes with macrophages
    • etal.
    • Schwendener RA, etal. The effects of charge and size on the interaction of unilamellar liposomes with macrophages. Biochim Biophys Acta 1984; 772: 93-101.
    • (1984) Biochim Biophys Acta , vol.772 , pp. 93-101
    • Schwendener, R.A.1
  • 148
    • 70350503410 scopus 로고    scopus 로고
    • Freeze-dried liposomes as potential carriers for ocular administration of cytochrome c against selenite cataract formation
    • etal.
    • Zhang J, etal. Freeze-dried liposomes as potential carriers for ocular administration of cytochrome c against selenite cataract formation. J Pharm Pharmacol 2009; 61: 1171-1178.
    • (2009) J Pharm Pharmacol , vol.61 , pp. 1171-1178
    • Zhang, J.1
  • 149
    • 0021462101 scopus 로고
    • Pilocarpine hydrochloride liposomes: Characterization in vitro and preliminary evaluation in vivo in rabbit eye
    • etal.
    • Benita S, etal. Pilocarpine hydrochloride liposomes: characterization in vitro and preliminary evaluation in vivo in rabbit eye. J Microencapsul 1986; 1: 203-216.
    • (1986) J Microencapsul , vol.1 , pp. 203-216
    • Benita, S.1
  • 150
    • 0020551477 scopus 로고
    • Liposomal ophthalmic drug delivery system. I. Triamcinalone acetonide
    • Singh K, Mezei M,. Liposomal ophthalmic drug delivery system. I. Triamcinalone acetonide. Int J Pharm 1983; 16: 339-344.
    • (1983) Int J Pharm , vol.16 , pp. 339-344
    • Singh, K.1    Mezei, M.2
  • 151
    • 0021236361 scopus 로고
    • Liposomal ophthalmic drug delivery system. II. Dihydrostreptomycin sulphate
    • Singh K, Mezei M,. Liposomal ophthalmic drug delivery system. II. Dihydrostreptomycin sulphate. Int J Pharm 1984; 19: 263-269.
    • (1984) Int J Pharm , vol.19 , pp. 263-269
    • Singh, K.1    Mezei, M.2
  • 152
    • 82955233600 scopus 로고    scopus 로고
    • Optimized flurbiprofen cationic liposomes. in situ gelling system of thermosensitive polymers for ocular delivery
    • etal.
    • He L, etal. Optimized flurbiprofen cationic liposomes. In situ gelling system of thermosensitive polymers for ocular delivery. J Appl Polym Sci 2012; 123: 3363-3374.
    • (2012) J Appl Polym Sci , vol.123 , pp. 3363-3374
    • He, L.1
  • 153
    • 77950917976 scopus 로고    scopus 로고
    • Ciprofloxacin as ocular liposomal hydrogel
    • Hosny KM,. Ciprofloxacin as ocular liposomal hydrogel. AAPS PharmSciTech 2010; 11: 241-246.
    • (2010) AAPS PharmSciTech , vol.11 , pp. 241-246
    • Hosny, K.M.1
  • 154
    • 0036139020 scopus 로고    scopus 로고
    • Intravitreal delivery of oligonucleotides by sterically stabilized liposomes
    • etal.
    • Bochot A, etal. Intravitreal delivery of oligonucleotides by sterically stabilized liposomes. Invest Ophthalmol Vis Sci 2002; 43: 253-259.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 253-259
    • Bochot, A.1
  • 155
    • 0025667736 scopus 로고
    • Synthetic cationic amphiphiles for liposome-mediated DNA transfection
    • etal.
    • Ito A, etal. Synthetic cationic amphiphiles for liposome-mediated DNA transfection. Biochem Int 1990; 22: 235-241.
    • (1990) Biochem Int , vol.22 , pp. 235-241
    • Ito, A.1
  • 156
    • 0038054050 scopus 로고    scopus 로고
    • Polycation liposome-mediated gene transfer in vivo
    • etal.
    • Matsuura M, etal. Polycation liposome-mediated gene transfer in vivo. Biochim Biophys Acta 2003; 1612: 136-143.
    • (2003) Biochim Biophys Acta , vol.1612 , pp. 136-143
    • Matsuura, M.1
  • 157
    • 2942583144 scopus 로고    scopus 로고
    • In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits
    • etal.
    • Kawakami S, etal. In vivo gene transfection via intravitreal injection of cationic liposome/plasmid DNA complexes in rabbits. Int J Pharm 2004; 278: 255-262.
    • (2004) Int J Pharm , vol.278 , pp. 255-262
    • Kawakami, S.1
  • 158
    • 33751272909 scopus 로고    scopus 로고
    • Non-viral ocular gene therapy: Potential ocular terapeutic avenues
    • etal.
    • Bloquel C, etal. Non-viral ocular gene therapy: potential ocular terapeutic avenues. Adv Drug Deliv Rev 2006; 58: 1224-1242.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1224-1242
    • Bloquel, C.1
  • 159
    • 34548623989 scopus 로고    scopus 로고
    • Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer
    • etal.
    • Sanders NN, etal. Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer. J Control Release 2007; 122: 226-235.
    • (2007) J Control Release , vol.122 , pp. 226-235
    • Sanders, N.N.1
  • 160
    • 84870252557 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Production, characterization and applications
    • Mehnert W, Mäder K,. Solid lipid nanoparticles: production, characterization and applications. Adv Drug Deliv Rev 2012; 64: 83-101.
    • (2012) Adv Drug Deliv Rev , vol.64 , pp. 83-101
    • Mehnert, W.1    Mäder, K.2
  • 161
    • 84858858095 scopus 로고    scopus 로고
    • Lipid nanoparticles as novel delivery systems for cosmetics and dermal pharmaceuticals
    • Puglia C, Bonina F,. Lipid nanoparticles as novel delivery systems for cosmetics and dermal pharmaceuticals. Expert Opin Drug Deliv 2012; 9: 429-441.
    • (2012) Expert Opin Drug Deliv , vol.9 , pp. 429-441
    • Puglia, C.1    Bonina, F.2
  • 162
    • 80052863988 scopus 로고    scopus 로고
    • SLN, NLC, LDC: State of the art in drug and active delivery
    • Attama AA,. SLN, NLC, LDC: state of the art in drug and active delivery. Recent Pat Drug Deliv Formul 2011; 5: 178-187.
    • (2011) Recent Pat Drug Deliv Formul , vol.5 , pp. 178-187
    • Attama, A.A.1
  • 163
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations
    • etal.
    • Müller RH, etal. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv Drug Deliv Rev 2002; 54: 131-155.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 131-155
    • Müller, R.H.1
  • 164
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Production, characterization and applications
    • Mehnert W, Mäder K,. Solid lipid nanoparticles: production, characterization and applications. Adv Drug Deliv Rev 2001; 47: 165-196.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 165-196
    • Mehnert, W.1    Mäder, K.2
  • 165
    • 84868353989 scopus 로고    scopus 로고
    • Nanostructured lipid carriers system: Recent advances in drug delivery
    • etal.
    • Iqbal MA, etal. Nanostructured lipid carriers system: recent advances in drug delivery. J Drug Target 2012; 20: 813-830.
    • (2012) J Drug Target , vol.20 , pp. 813-830
    • Iqbal, M.A.1
  • 166
    • 84866517859 scopus 로고    scopus 로고
    • Further investigation of nanostructured lipid carriers as an ocular delivery system: In vivo transcorneal mechanism and in vitro release study
    • etal.
    • Tian BC, etal. Further investigation of nanostructured lipid carriers as an ocular delivery system: in vivo transcorneal mechanism and in vitro release study. Colloids Surf B Biointerfaces 2013; 102: 251-256.
    • (2013) Colloids Surf B Biointerfaces , vol.102 , pp. 251-256
    • Tian, B.C.1
  • 167
    • 0037151496 scopus 로고    scopus 로고
    • Nanostructured lipid matrices for improved microencapsulation of drugs
    • etal.
    • Muller RH, etal. Nanostructured lipid matrices for improved microencapsulation of drugs. Int J Pharm 2002; 242: 121-128.
    • (2002) Int J Pharm , vol.242 , pp. 121-128
    • Muller, R.H.1
  • 168
    • 0028897685 scopus 로고
    • Preparation and evaluation in vitro of colloidal lipospheres containing pilocarpine as ion-pair
    • etal.
    • Cavalli R, etal. Preparation and evaluation in vitro of colloidal lipospheres containing pilocarpine as ion-pair. Int J Pharm 1995; 117: 243-246.
    • (1995) Int J Pharm , vol.117 , pp. 243-246
    • Cavalli, R.1
  • 169
    • 0037093721 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin
    • etal.
    • Cavalli R, etal. Solid lipid nanoparticles (SLN) as ocular delivery system for tobramycin. Int J Pharm 2002; 238: 241-245.
    • (2002) Int J Pharm , vol.238 , pp. 241-245
    • Cavalli, R.1
  • 170
    • 84876285264 scopus 로고    scopus 로고
    • Part II: Enhancement of transcorneal delivery of gatifloxacin by solid lipid nanoparticles in comparison to commercial aqueous eye drops
    • etal.
    • Abul Kalam M, etal. Part II: enhancement of transcorneal delivery of gatifloxacin by solid lipid nanoparticles in comparison to commercial aqueous eye drops. J Biomed Mater Res A 2012; 101: 1828-1836.
    • (2012) J Biomed Mater Res A , vol.101 , pp. 1828-1836
    • Abul Kalam, M.1
  • 171
    • 84874502028 scopus 로고    scopus 로고
    • Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir
    • Seyfoddin A, Al-Kassas R,. Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir. Drug Dev Ind Pharm 2012; 39: 508-519.
    • (2012) Drug Dev Ind Pharm , vol.39 , pp. 508-519
    • Seyfoddin, A.1    Al-Kassas, R.2
  • 172
    • 84870364134 scopus 로고    scopus 로고
    • Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide
    • etal.
    • Youshia J, etal. Design of cationic nanostructured heterolipid matrices for ocular delivery of methazolamide. Int J Nanomedicine 2012; 7: 2483-2496.
    • (2012) Int J Nanomedicine , vol.7 , pp. 2483-2496
    • Youshia, J.1
  • 173
    • 71549165819 scopus 로고    scopus 로고
    • Incorporation of liquid lipid in lipid nanoparticles for ocular drug delivery enhancement
    • etal.
    • Shen J, etal. Incorporation of liquid lipid in lipid nanoparticles for ocular drug delivery enhancement. Nanotechnology 2010; 21: 1-10.
    • (2010) Nanotechnology , vol.21 , pp. 1-10
    • Shen, J.1
  • 174
    • 67649101315 scopus 로고    scopus 로고
    • Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery
    • etal.
    • Shen J, etal. Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery. J Control Release 2009; 137: 217-223.
    • (2009) J Control Release , vol.137 , pp. 217-223
    • Shen, J.1
  • 175
    • 78349311591 scopus 로고    scopus 로고
    • Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: Improving in vivo ocular distribution
    • etal.
    • Shen J, etal. Thiolated nanostructured lipid carriers as a potential ocular drug delivery system for cyclosporine A: improving in vivo ocular distribution. Int J Pharm 2010; 402: 248-253.
    • (2010) Int J Pharm , vol.402 , pp. 248-253
    • Shen, J.1
  • 176
    • 75449109191 scopus 로고    scopus 로고
    • Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery
    • etal.
    • Basaran E, etal. Cyclosporine-A incorporated cationic solid lipid nanoparticles for ocular delivery. J Microencapsul 2010; 27: 37-47.
    • (2010) J Microencapsul , vol.27 , pp. 37-47
    • Basaran, E.1
  • 177
    • 0031667660 scopus 로고    scopus 로고
    • Evaluation of pluronic F127-based sustained-release ocular delivery systems for pilocarpine using the albino rabbit eye model
    • Desai SD, Blanchard J,. Evaluation of pluronic F127-based sustained-release ocular delivery systems for pilocarpine using the albino rabbit eye model. J Pharm Sci 1998; 87: 1190-1195.
    • (1998) J Pharm Sci , vol.87 , pp. 1190-1195
    • Desai, S.D.1    Blanchard, J.2
  • 178
    • 84863682818 scopus 로고    scopus 로고
    • Formulation and evaluation of micro hydrogel of Moxifloxacin hydrochloride
    • etal.
    • Nanjwade BK, etal. Formulation and evaluation of micro hydrogel of Moxifloxacin hydrochloride. Eur J Drug Metab Pharmacokinet 2012; 37: 117-123.
    • (2012) Eur J Drug Metab Pharmacokinet , vol.37 , pp. 117-123
    • Nanjwade, B.K.1
  • 179
    • 67349240739 scopus 로고    scopus 로고
    • Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response
    • etal.
    • Anumolu SS, etal. Design and evaluation of novel fast forming pilocarpine-loaded ocular hydrogels for sustained pharmacological response. J Control Release 2009; 137: 152-159.
    • (2009) J Control Release , vol.137 , pp. 152-159
    • Anumolu, S.S.1
  • 180
    • 38549141639 scopus 로고    scopus 로고
    • Pluronic F127-g-poly(acrylic acid) copolymers as in situ gelling vehicle for ophthalmic drug delivery system
    • etal.
    • Ma WD, etal. Pluronic F127-g-poly(acrylic acid) copolymers as in situ gelling vehicle for ophthalmic drug delivery system. Int J Pharm 2008; 350: 247-256.
    • (2008) Int J Pharm , vol.350 , pp. 247-256
    • Ma, W.D.1
  • 181
    • 64249129110 scopus 로고    scopus 로고
    • Synthesis of biodegradable amphiphilic thermo-responsive multiblock polycarbonate and its self-aggregation behavior in aqueous solution
    • etal.
    • Wang X, etal. Synthesis of biodegradable amphiphilic thermo-responsive multiblock polycarbonate and its self-aggregation behavior in aqueous solution. J Appl Polym Sci 2009; 112: 1425-1435.
    • (2009) J Appl Polym Sci , vol.112 , pp. 1425-1435
    • Wang, X.1
  • 182
    • 0037043105 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of Pluronic F127-based ocular delivery system for timolol maleate
    • El Kamel AH,. In vitro and in vivo evaluation of Pluronic F127-based ocular delivery system for timolol maleate. Int J Pharm 2002; 24: 47-55.
    • (2002) Int J Pharm , vol.24 , pp. 47-55
    • El Kamel, A.H.1
  • 183
    • 79955964137 scopus 로고    scopus 로고
    • Optimization and evaluation of thermoresponsive diclofenac sodium ophthalmic in situ gels
    • etal.
    • Asasutjarit R, etal. Optimization and evaluation of thermoresponsive diclofenac sodium ophthalmic in situ gels. Int J Pharm 2011; 411: 128-135.
    • (2011) Int J Pharm , vol.411 , pp. 128-135
    • Asasutjarit, R.1
  • 184
    • 0034602597 scopus 로고    scopus 로고
    • Carbopol/pluronic phase change solutions for ophthalmic drug delivery
    • Lin HR, Sung KC,. Carbopol/pluronic phase change solutions for ophthalmic drug delivery. J Control Release 2000; 69: 379-388.
    • (2000) J Control Release , vol.69 , pp. 379-388
    • Lin, H.R.1    Sung, K.C.2
  • 185
    • 33747125733 scopus 로고    scopus 로고
    • Evaluation of carbopol-methyl cellulose based sustained-release ocular delivery system for pefloxacin mesylate using rabbit eye model
    • etal.
    • Sultana Y, etal. Evaluation of carbopol-methyl cellulose based sustained-release ocular delivery system for pefloxacin mesylate using rabbit eye model. Pharm Dev Technol 2006; 11: 313-319.
    • (2006) Pharm Dev Technol , vol.11 , pp. 313-319
    • Sultana, Y.1
  • 186
    • 33846141485 scopus 로고    scopus 로고
    • Preparation and evaluation of a Carbopol/HPMC-based in situ gelling ophthalmic system for puerarin
    • etal.
    • Wu C, etal. Preparation and evaluation of a Carbopol/HPMC-based in situ gelling ophthalmic system for puerarin. Yakugaku Zasshi 2007; 127: 183-191.
    • (2007) Yakugaku Zasshi , vol.127 , pp. 183-191
    • Wu, C.1
  • 187
    • 79955643091 scopus 로고    scopus 로고
    • Design and evaluation of baicalin-containing in situ pH-triggered gelling system for sustained ophthalmic drug delivery
    • etal.
    • Wu H, etal. Design and evaluation of baicalin-containing in situ pH-triggered gelling system for sustained ophthalmic drug delivery. Int J Pharm 2011; 410: 31-40.
    • (2011) Int J Pharm , vol.410 , pp. 31-40
    • Wu, H.1
  • 188
    • 0014766601 scopus 로고
    • Use of hydrophilic contact lenses to increase ocular penetration of topical drugs
    • Waltman SR, Kaufman HE,. Use of hydrophilic contact lenses to increase ocular penetration of topical drugs. Invest Ophthalmol 1970; 9: 250-255.
    • (1970) Invest Ophthalmol , vol.9 , pp. 250-255
    • Waltman, S.R.1    Kaufman, H.E.2
  • 189
    • 77749248902 scopus 로고    scopus 로고
    • Preparation and evaluation of a contact lens vehicle for puerarin delivery
    • etal.
    • Xu J, etal. Preparation and evaluation of a contact lens vehicle for puerarin delivery. J Biomater Sci Polym Ed 2010; 21: 271-288.
    • (2010) J Biomater Sci Polym Ed , vol.21 , pp. 271-288
    • Xu, J.1
  • 190
    • 80052534766 scopus 로고    scopus 로고
    • Extended cyclosporine delivery by silicone-hydrogel contact lenses
    • Peng CC, Chauhan AJ,. Extended cyclosporine delivery by silicone-hydrogel contact lenses. J Control Release 2011; 154: 267-274.
    • (2011) J Control Release , vol.154 , pp. 267-274
    • Peng, C.C.1    Chauhan, A.J.2
  • 191
    • 84860678768 scopus 로고    scopus 로고
    • Contact lenses in ocular therapeutics
    • Gupta H, Aqil M,. Contact lenses in ocular therapeutics. Drug Discov Today 2012; 17: 522-527.
    • (2012) Drug Discov Today , vol.17 , pp. 522-527
    • Gupta, H.1    Aqil, M.2
  • 192
    • 3142618394 scopus 로고    scopus 로고
    • Ophthalmic drug delivery through contact lenses
    • Gulsen D, Chauhan A,. Ophthalmic drug delivery through contact lenses. Invest Ophthalmol Vis Sci 2004; 45: 2342-2347.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 2342-2347
    • Gulsen, D.1    Chauhan, A.2
  • 193
    • 13844267655 scopus 로고    scopus 로고
    • Dispersion of microemulsion drops in HEMA hydrogel: A potential ophthalmic drug delivery vehicle
    • Gulsen D, Chauhan A,. Dispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicle. Int J Pharm 2005; 292: 95-117.
    • (2005) Int J Pharm , vol.292 , pp. 95-117
    • Gulsen, D.1    Chauhan, A.2
  • 194
    • 29144462085 scopus 로고    scopus 로고
    • Dispersion of DMPC liposomes in contact lenses for ophthalmic drug delivery
    • etal.
    • Gulsen D, etal. Dispersion of DMPC liposomes in contact lenses for ophthalmic drug delivery. Curr Eye Res 2005; 30: 1071-1080.
    • (2005) Curr Eye Res , vol.30 , pp. 1071-1080
    • Gulsen, D.1
  • 195
    • 47949125220 scopus 로고    scopus 로고
    • Ophthalmic delivery of Cyclosporine A from Brij-97 microemulsion and surfactant-laden p-HEMA hydrogels
    • Kapoor Y, Chauhan A,. Ophthalmic delivery of Cyclosporine A from Brij-97 microemulsion and surfactant-laden p-HEMA hydrogels. Int J Pharm 2008; 361: 222-229.
    • (2008) Int J Pharm , vol.361 , pp. 222-229
    • Kapoor, Y.1    Chauhan, A.2
  • 196
    • 34748918564 scopus 로고    scopus 로고
    • Antibacterial activity of contact lenses bearing surface-immobilized layers of intact liposomes loaded with levofloxacin
    • etal.
    • Danion A, etal. Antibacterial activity of contact lenses bearing surface-immobilized layers of intact liposomes loaded with levofloxacin. J Pharm Sci 2007; 96: 2350-2363.
    • (2007) J Pharm Sci , vol.96 , pp. 2350-2363
    • Danion, A.1
  • 197
    • 84861137328 scopus 로고    scopus 로고
    • Sustained ocular delivery of ciprofloxacin using nanospheres and conventional contact lens materials
    • etal.
    • Garhwal R, etal. Sustained ocular delivery of ciprofloxacin using nanospheres and conventional contact lens materials. Invest Ophthalmol Vis Sci 2012; 53: 1341-1352.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 1341-1352
    • Garhwal, R.1
  • 198
    • 79955421849 scopus 로고    scopus 로고
    • Bioinspired imprinted PHEMA-hydrogels for ocular delivery of carbonic anhydrase inhibitor drugs
    • etal.
    • Ribeiro A, etal. Bioinspired imprinted PHEMA-hydrogels for ocular delivery of carbonic anhydrase inhibitor drugs. Biomacromolecules 2011; 12: 701-709.
    • (2011) Biomacromolecules , vol.12 , pp. 701-709
    • Ribeiro, A.1
  • 199
    • 4744363261 scopus 로고    scopus 로고
    • Ocular release of timolol from molecularly imprinted soft contact lenses
    • etal.
    • Hiratani H, etal. Ocular release of timolol from molecularly imprinted soft contact lenses. Biomaterials 2005; 26: 1293-1298.
    • (2005) Biomaterials , vol.26 , pp. 1293-1298
    • Hiratani, H.1
  • 200
    • 33745480945 scopus 로고    scopus 로고
    • Imprinted soft contact lenses as norfloxacin delivery systems
    • etal.
    • Alvarez-Lorenzo C, etal. Imprinted soft contact lenses as norfloxacin delivery systems. J Control Release 2006; 113: 236-244.
    • (2006) J Control Release , vol.113 , pp. 236-244
    • Alvarez-Lorenzo, C.1
  • 201
    • 84861099990 scopus 로고    scopus 로고
    • In vitro controlled release of an anti-inflammatory from daily disposable therapeutic contact lenses under physiological ocular tear flow
    • Tieppo A,. In vitro controlled release of an anti-inflammatory from daily disposable therapeutic contact lenses under physiological ocular tear flow. Eur J Pharm Biopharm 2012; 81: 170-177.
    • (2012) Eur J Pharm Biopharm , vol.81 , pp. 170-177
    • Tieppo, A.1
  • 202
    • 43049083390 scopus 로고    scopus 로고
    • Molecularly imprinted polymers with specific recognition for macromolecules and proteins
    • Bergmann NM, Peppas NA,. Molecularly imprinted polymers with specific recognition for macromolecules and proteins. Prog Polym Sci 2008; 33: 271-288.
    • (2008) Prog Polym Sci , vol.33 , pp. 271-288
    • Bergmann, N.M.1    Peppas, N.A.2
  • 203
    • 67650001905 scopus 로고    scopus 로고
    • Mimicking biological delivery through feedback-controlled, recognitive drug release systems based on molecular imprinting methods
    • Kryscio DR, Peppas NA,. Mimicking biological delivery through feedback-controlled, recognitive drug release systems based on molecular imprinting methods. AIChE J 2009; 55: 1311-1324.
    • (2009) AIChE J , vol.55 , pp. 1311-1324
    • Kryscio, D.R.1    Peppas, N.A.2
  • 204
    • 84857368995 scopus 로고    scopus 로고
    • Sustained in vivo release from imprinted therapeutic contact lenses
    • etal.
    • Tieppo A, etal. Sustained in vivo release from imprinted therapeutic contact lenses. J Control Release 2012; 157: 391-397.
    • (2012) J Control Release , vol.157 , pp. 391-397
    • Tieppo, A.1
  • 205
    • 39149109626 scopus 로고    scopus 로고
    • Nanotechnology in ocular drug delivery
    • etal.
    • Sahoo SK, etal. Nanotechnology in ocular drug delivery. Drug Discov Today 2008; 13: 144-151.
    • (2008) Drug Discov Today , vol.13 , pp. 144-151
    • Sahoo, S.K.1
  • 206
    • 0037336290 scopus 로고    scopus 로고
    • Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression
    • etal.
    • Kompella UB, etal. Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression. Invest Ophthalmol Vis Sci 2003; 44: 1192-1201.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 1192-1201
    • Kompella, U.B.1
  • 207
    • 33750383647 scopus 로고    scopus 로고
    • Luteinizing hormone- releasing hormone agonist and transferri functionalizations enhance nanoparticle delivery in a novel bovine ex vivo eye model
    • etal.
    • Kompella UB, etal. Luteinizing hormone- releasing hormone agonist and transferri functionalizations enhance nanoparticle delivery in a novel bovine ex vivo eye model. Mol Vis 2006; 12: 1185-1198.
    • (2006) Mol Vis , vol.12 , pp. 1185-1198
    • Kompella, U.B.1
  • 208
    • 79955026932 scopus 로고    scopus 로고
    • Ocular sustained release nanoparticles containing stereoisomeric dipeptide prodrugs of acyclovir
    • etal.
    • Jwala J, etal. Ocular sustained release nanoparticles containing stereoisomeric dipeptide prodrugs of acyclovir. J Ocul Pharmacol Ther 2011; 27: 163-172.
    • (2011) J Ocul Pharmacol Ther , vol.27 , pp. 163-172
    • Jwala, J.1
  • 209
    • 67349084376 scopus 로고    scopus 로고
    • Polymeric nanoparticulate system: A potential approach for ocular drug delivery
    • etal.
    • Nagarwal RC, etal. Polymeric nanoparticulate system: a potential approach for ocular drug delivery. J Control Release 2009; 136: 2-13.
    • (2009) J Control Release , vol.136 , pp. 2-13
    • Nagarwal, R.C.1
  • 210
    • 3042731986 scopus 로고    scopus 로고
    • Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene
    • etal.
    • Bucolo C, etal. Eudragit RL100 nanoparticle system for the ophthalmic delivery of cloricromene. J Pharm Pharmacol 2004; 56: 841-846.
    • (2004) J Pharm Pharmacol , vol.56 , pp. 841-846
    • Bucolo, C.1
  • 211
    • 0036020063 scopus 로고    scopus 로고
    • Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen
    • etal.
    • Pignatello R, etal. Eudragit RS100 nanosuspensions for the ophthalmic controlled delivery of ibuprofen. Eur J Pharm Sci 2002; 16: 53-61.
    • (2002) Eur J Pharm Sci , vol.16 , pp. 53-61
    • Pignatello, R.1
  • 212
    • 78649739026 scopus 로고    scopus 로고
    • In vivo evaluation of novel nanoparticles containing dexamethasone for ocular drug delivery on rabbit eye
    • etal.
    • Rafie F, etal. In vivo evaluation of novel nanoparticles containing dexamethasone for ocular drug delivery on rabbit eye. Curr Eye Res 2010; 35: 1081-1089.
    • (2010) Curr Eye Res , vol.35 , pp. 1081-1089
    • Rafie, F.1
  • 213
    • 34447254990 scopus 로고    scopus 로고
    • Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs
    • etal.
    • Kassem MA, etal. Nanosuspension as an ophthalmic delivery system for certain glucocorticoid drugs. Int J Pharm 2007; 340: 126-133.
    • (2007) Int J Pharm , vol.340 , pp. 126-133
    • Kassem, M.A.1
  • 214
    • 0029347541 scopus 로고
    • Ocular drug delivery conventional ocular formulations
    • Lang JC,. Ocular drug delivery conventional ocular formulations. Adv Drug Deliv Rev 1995; 16: 39-43.
    • (1995) Adv Drug Deliv Rev , vol.16 , pp. 39-43
    • Lang, J.C.1
  • 215
    • 33751167018 scopus 로고    scopus 로고
    • Industrial perspective in ocular drug delivery
    • Ali Y, Lehmussaari K,. Industrial perspective in ocular drug delivery. Adv Drug Deliv Rev 2006; 58: 1258-1268.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1258-1268
    • Ali, Y.1    Lehmussaari, K.2
  • 216
    • 84872330873 scopus 로고    scopus 로고
    • Polymeric nanoparticles augment the ocular hypotensive effect of melatonin in rabbits
    • etal.
    • Musumeci T, etal. Polymeric nanoparticles augment the ocular hypotensive
    • (2012) Int J Pharm , vol.440 , pp. 135-140
    • Musumeci, T.1
  • 217
    • 12444299613 scopus 로고    scopus 로고
    • Influence of preparation conditions on acyclovir-loaded poly-d,l-lactic acid nanospheres and effect of PEG coating on ocular drug bioavailability
    • etal.
    • Giannavola C, etal. Influence of preparation conditions on acyclovir-loaded poly-d,l-lactic acid nanospheres and effect of PEG coating on ocular drug bioavailability. Pharm Res 2003; 20: 584-590.
    • (2003) Pharm Res , vol.20 , pp. 584-590
    • Giannavola, C.1
  • 218
    • 0035342007 scopus 로고    scopus 로고
    • Poly (amidoamine) (PAMAM) dendrimers: From biomimicry to drug delivery and biomedical applications
    • Esfand R, Tomalia DA,. Poly (amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discov Today 2001; 6: 427-436.
    • (2001) Drug Discov Today , vol.6 , pp. 427-436
    • Esfand, R.1    Tomalia, D.A.2
  • 219
    • 78650316044 scopus 로고    scopus 로고
    • Biomedical applications of dendrimers: A tutorial
    • Mintzer MA, Grinstaff MW,. Biomedical applications of dendrimers: a tutorial. Chem Soc Rev 2011; 40: 173-190.
    • (2011) Chem Soc Rev , vol.40 , pp. 173-190
    • Mintzer, M.A.1    Grinstaff, M.W.2
  • 220
    • 80052280058 scopus 로고    scopus 로고
    • Dendrimer pharmacokinetics: The effect of size, structure and surface characteristics on ADME properties
    • etal.
    • Kaminskas LM, etal. Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties. Nanomedicine (Lond) 2011; 6: 1063-1084.
    • (2011) Nanomedicine (Lond) , vol.6 , pp. 1063-1084
    • Kaminskas, L.M.1
  • 221
    • 0344466792 scopus 로고    scopus 로고
    • Designing dendrimers for drug delivery
    • Liu M, Fréchet JM,. Designing dendrimers for drug delivery. Pharm Sci Technolo Today 1999; 2: 393-401.
    • (1999) Pharm Sci Technolo Today , vol.2 , pp. 393-401
    • Liu, M.1    Fréchet, J.M.2
  • 222
    • 59849100122 scopus 로고    scopus 로고
    • Poly(amidoamine) dendrimer-drug conjugates with disulfide linkages for intracellular drug delivery
    • etal.
    • Kurtoglu YE, etal. Poly(amidoamine) dendrimer-drug conjugates with disulfide linkages for intracellular drug delivery. Biomaterials 2009; 30: 2112-2121.
    • (2009) Biomaterials , vol.30 , pp. 2112-2121
    • Kurtoglu, Y.E.1
  • 223
    • 58149092257 scopus 로고    scopus 로고
    • Dendrimer-drug conjugates for tailored intracellular drug release based on glutathione levels
    • etal.
    • Navath RS, etal. Dendrimer-drug conjugates for tailored intracellular drug release based on glutathione levels. Bioconjug Chem 2008; 19: 2446-2455.
    • (2008) Bioconjug Chem , vol.19 , pp. 2446-2455
    • Navath, R.S.1
  • 224
    • 61949478182 scopus 로고    scopus 로고
    • Bifunctional dendrimers: From robust synthesis and accelerated one-pot postfunctionalization strategy to potential applications
    • etal.
    • Antoni P, etal. Bifunctional dendrimers: from robust synthesis and accelerated one-pot postfunctionalization strategy to potential applications. Angew Chem Int Ed Engl 2009; 48: 2126-2130.
    • (2009) Angew Chem Int Ed Engl , vol.48 , pp. 2126-2130
    • Antoni, P.1
  • 225
    • 0038023185 scopus 로고    scopus 로고
    • Drug complexation, in vitro release and cellular entry of dendrimers and hyperbranched polymers
    • etal.
    • Kolhe P, etal. Drug complexation, in vitro release and cellular entry of dendrimers and hyperbranched polymers. Int J Pharm 2003; 259: 143-160.
    • (2003) Int J Pharm , vol.259 , pp. 143-160
    • Kolhe, P.1
  • 226
    • 15244339200 scopus 로고    scopus 로고
    • Synthesis, cellular transport, and activity of polyamidoamine dendrimer-methylprednisolone conjugates
    • etal.
    • Khandare J, etal. Synthesis, cellular transport, and activity of polyamidoamine dendrimer-methylprednisolone conjugates. Bioconjug Chem 2005; 16: 330-337.
    • (2005) Bioconjug Chem , vol.16 , pp. 330-337
    • Khandare, J.1
  • 227
    • 0021586266 scopus 로고
    • A new class of polymers: Starburst dendritic macromolecules
    • etal.
    • Tomalia DA, etal. A new class of polymers: starburst dendritic macromolecules. Polym J 1985; 17: 117-132.
    • (1985) Polym J , vol.17 , pp. 117-132
    • Tomalia, D.A.1
  • 228
    • 0034005436 scopus 로고    scopus 로고
    • Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo
    • etal.
    • Malik N, etal. Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo. J Control Release 2000; 65: 133-148.
    • (2000) J Control Release , vol.65 , pp. 133-148
    • Malik, N.1
  • 229
    • 33744914093 scopus 로고    scopus 로고
    • PAMAM dendrimers for efficient siRNA delivery and potent gene silencing
    • etal.
    • Zhou J, etal. PAMAM dendrimers for efficient siRNA delivery and potent gene silencing. Chem Commun (Camb) 2006; 14: 2362-2364.
    • (2006) Chem Commun (Camb) , vol.14 , pp. 2362-2364
    • Zhou, J.1
  • 230
    • 0029945799 scopus 로고    scopus 로고
    • Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers
    • etal.
    • Bielinska A, etal. Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers. Nucleic Acids Res 1996; 24: 2176-2182.
    • (1996) Nucleic Acids Res , vol.24 , pp. 2176-2182
    • Bielinska, A.1
  • 231
    • 4544332801 scopus 로고    scopus 로고
    • Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide
    • etal.
    • Marano RJ, etal. Inhibition of in vitro VEGF expression and choroidal neovascularization by synthetic dendrimer peptide mediated delivery of a sense oligonucleotide. Exp Eye Res 2004; 79: 525-535.
    • (2004) Exp Eye Res , vol.79 , pp. 525-535
    • Marano, R.J.1
  • 232
    • 27544499791 scopus 로고    scopus 로고
    • Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: A long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity
    • etal.
    • Marano RJ, etal. Dendrimer delivery of an anti-VEGF oligonucleotide into the eye: a long-term study into inhibition of laser-induced CNV, distribution, uptake and toxicity. Gene Ther 2005; 12: 1544-1550.
    • (2005) Gene Ther , vol.12 , pp. 1544-1550
    • Marano, R.J.1
  • 233
    • 33646809712 scopus 로고    scopus 로고
    • Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition
    • etal.
    • Parekh HS, etal. Synthesis of a library of polycationic lipid core dendrimers and their evaluation in the delivery of an oligonucleotide with hVEGF inhibition. Bioorg Med Chem 2006; 14: 4775-4780.
    • (2006) Bioorg Med Chem , vol.14 , pp. 4775-4780
    • Parekh, H.S.1
  • 234
    • 0347360162 scopus 로고    scopus 로고
    • Photodynamic therapy of skin cancer: Controlled drug delivery of 5-ALA and its esters
    • etal.
    • Lopez RF, etal. Photodynamic therapy of skin cancer: controlled drug delivery of 5-ALA and its esters. Adv Drug Deliv Rev 2004; 56: 77-94.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 77-94
    • Lopez, R.F.1
  • 235
    • 70350619628 scopus 로고    scopus 로고
    • In vivo transungual iontophoresis: Effect of DC current application on ionic transport and on transonychial water loss
    • Dutet J, Delgado-Charro MB,. In vivo transungual iontophoresis: effect of DC current application on ionic transport and on transonychial water loss. J Control Release 2009; 140: 117-125.
    • (2009) J Control Release , vol.140 , pp. 117-125
    • Dutet, J.1    Delgado-Charro, M.B.2
  • 236
    • 73649134378 scopus 로고    scopus 로고
    • Excised porcine cornea integrity evaluation in an in vitro model of iontophoretic ocular research
    • etal.
    • Gratieri T, etal. Excised porcine cornea integrity evaluation in an in vitro model of iontophoretic ocular research. Ophthalmic Res 2010; 43: 208-216.
    • (2010) Ophthalmic Res , vol.43 , pp. 208-216
    • Gratieri, T.1
  • 237
    • 70350712156 scopus 로고    scopus 로고
    • Electrically assisted delivery of macromolecules into the corneal epithelium
    • etal.
    • Hao J, etal. Electrically assisted delivery of macromolecules into the corneal epithelium. Exp Eye Res 2009; 89: 934-941.
    • (2009) Exp Eye Res , vol.89 , pp. 934-941
    • Hao, J.1
  • 238
    • 0035659460 scopus 로고    scopus 로고
    • Contributions of electromigration and electroosmosis to iontophoretic drug delivery
    • etal.
    • Marro D, etal. Contributions of electromigration and electroosmosis to iontophoretic drug delivery. Pharm Res 2001; 18: 1701-1708.
    • (2001) Pharm Res , vol.18 , pp. 1701-1708
    • Marro, D.1
  • 239
    • 84910977643 scopus 로고
    • Penetration of penicillin into the eye
    • Von Sallmann L, Meyer K,. Penetration of penicillin into the eye. Arch Ophthalmol 1944; 31: 1-7.
    • (1944) Arch Ophthalmol , vol.31 , pp. 1-7
    • Von Sallmann, L.1    Meyer, K.2
  • 240
    • 84899474328 scopus 로고
    • Penicillin and sulfadiazine in the treatment of experimental intraocular infections with Staphylococcu aureus and Clostridium welchii
    • Von Sallmann L,. Penicillin and sulfadiazine in the treatment of experimental intraocular infections with Staphylococcu aureus and Clostridium welchii. Arch Ophthalmol 1944; 31: 54-61.
    • (1944) Arch Ophthalmol , vol.31 , pp. 54-61
    • Von Sallmann, L.1
  • 241
    • 0021690562 scopus 로고
    • A fresh look at iontophoresis
    • Hughes L, Maurice DM,. A fresh look at iontophoresis. Arch Ophthalmol 1984; 102: 1825-1829.
    • (1984) Arch Ophthalmol , vol.102 , pp. 1825-1829
    • Hughes, L.1    Maurice, D.M.2
  • 242
    • 0842309502 scopus 로고    scopus 로고
    • Iontophoresis-gentamicin delivery into the rabbit cornea, using a hydrogel delivery probe
    • Frucht-Pery J,. Iontophoresis-gentamicin delivery into the rabbit cornea, using a hydrogel delivery probe. Exp Eye Res 2004; 78: 745-749.
    • (2004) Exp Eye Res , vol.78 , pp. 745-749
    • Frucht-Pery, J.1
  • 243
    • 23944493904 scopus 로고    scopus 로고
    • Transcorneal and transscleral iontophoresis of dexamethasone phosphate using drug loaded hydrogel
    • etal.
    • Eljarrat-Binstock E, etal. Transcorneal and transscleral iontophoresis of dexamethasone phosphate using drug loaded hydrogel. J Control Release 2005; 106: 386-390.
    • (2005) J Control Release , vol.106 , pp. 386-390
    • Eljarrat-Binstock, E.1
  • 244
    • 0024421694 scopus 로고
    • Transscleral iontophoresis of dexamethasone
    • etal.
    • Lam T, etal. Transscleral iontophoresis of dexamethasone. Arch Ophthalmol 1989; 107: 1368-1371.
    • (1989) Arch Ophthalmol , vol.107 , pp. 1368-1371
    • Lam, T.1
  • 245
    • 0030700775 scopus 로고    scopus 로고
    • Iontophoresis of dexamethasone in the treatment of endotoxin-induced- uveitis in rats
    • etal.
    • Behar-Cohen FF, etal. Iontophoresis of dexamethasone in the treatment of endotoxin-induced-uveitis in rats. Exp Eye Res 1997; 65: 533-545.
    • (1997) Exp Eye Res , vol.65 , pp. 533-545
    • Behar-Cohen, F.F.1
  • 246
    • 0036346995 scopus 로고    scopus 로고
    • Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: Influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels
    • etal.
    • Behar-Cohen FF, etal. Transscleral Coulomb-controlled iontophoresis of methylprednisolone into the rabbit eye: influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels. Exp Eye Res 2002; 74: 51-59.
    • (2002) Exp Eye Res , vol.74 , pp. 51-59
    • Behar-Cohen, F.F.1
  • 247
    • 44349188483 scopus 로고    scopus 로고
    • Methylprednisolone delivery to the back of the eye using hydrogel iontophoresis
    • etal.
    • Eljarrat-Binstock E, etal. Methylprednisolone delivery to the back of the eye using hydrogel iontophoresis. J Ocul Pharmacol Ther 2008; 24: 344-350.
    • (2008) J Ocul Pharmacol Ther , vol.24 , pp. 344-350
    • Eljarrat-Binstock, E.1
  • 248
    • 61549127583 scopus 로고    scopus 로고
    • Transscleral iontophoretic and intravitreal delivery of a macromolecule: Study of ocular distribution in vivo and postmortem with MRI
    • etal.
    • Molokhia SA, etal. Transscleral iontophoretic and intravitreal delivery of a macromolecule: study of ocular distribution in vivo and postmortem with MRI. Exp Eye Res 2009; 88: 418-425.
    • (2009) Exp Eye Res , vol.88 , pp. 418-425
    • Molokhia, S.A.1
  • 249
    • 79953211477 scopus 로고    scopus 로고
    • Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis
    • etal.
    • Li SK, etal. Effective electrophoretic mobilities and charges of anti-VEGF proteins determined by capillary zone electrophoresis. J Pharm Biomed Anal 2011; 55: 603-607.
    • (2011) J Pharm Biomed Anal , vol.55 , pp. 603-607
    • Li, S.K.1
  • 250
    • 2142696596 scopus 로고    scopus 로고
    • Magnetic resonance imaging study of current and ion delivery into the eye during transscleral and transcorneal iontophoresis
    • etal.
    • Li SK, etal. Magnetic resonance imaging study of current and ion delivery into the eye during transscleral and transcorneal iontophoresis. Invest Ophthalmol Vis Sci 2004; 45: 1224-1231.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 1224-1231
    • Li, S.K.1
  • 251
    • 0038303190 scopus 로고    scopus 로고
    • Tolerance of ocular iontophoresis in healthy volunteers
    • etal.
    • Parkinson TM, etal. Tolerance of ocular iontophoresis in healthy volunteers. J Ocul Pharmacol Ther 2003; 19: 145-151.
    • (2003) J Ocul Pharmacol Ther , vol.19 , pp. 145-151
    • Parkinson, T.M.1
  • 252
    • 33847781066 scopus 로고    scopus 로고
    • Electrically assisted ocular gene therapy
    • etal.
    • Bejjani RA, etal. Electrically assisted ocular gene therapy. Surv Ophthalmol 2007; 52: 196-208.
    • (2007) Surv Ophthalmol , vol.52 , pp. 196-208
    • Bejjani, R.A.1
  • 253
    • 0035191885 scopus 로고    scopus 로고
    • Induction of gene into the rabbit eye by iontophoresis: Preliminary report
    • etal.
    • Asahara T, etal. Induction of gene into the rabbit eye by iontophoresis: preliminary report. Jpn J Ophthalmol 2001; 45: 31-39.
    • (2001) Jpn J Ophthalmol , vol.45 , pp. 31-39
    • Asahara, T.1
  • 254
    • 0036069080 scopus 로고    scopus 로고
    • Down-regulation of NOSII gene expression by iontophoresis of anti-senseoligonucleotide in endotoxin-induced uveitis
    • etal.
    • Voigt M, etal. Down-regulation of NOSII gene expression by iontophoresis of anti-senseoligonucleotide in endotoxin-induced uveitis. Biochem Biophys Res Commun 2002; 295: 336-341.
    • (2002) Biochem Biophys Res Commun , vol.295 , pp. 336-341
    • Voigt, M.1
  • 255
    • 24344470207 scopus 로고    scopus 로고
    • Delivery of antisense oligonucleotide to the cornea by iontophoresis
    • etal.
    • Berdugo M, etal. Delivery of antisense oligonucleotide to the cornea by iontophoresis. Antisense Nucleic Acid Drug Dev 2003; 13: 107-114.
    • (2003) Antisense Nucleic Acid Drug Dev , vol.13 , pp. 107-114
    • Berdugo, M.1
  • 256
    • 38749127952 scopus 로고    scopus 로고
    • Charged nanoparticles delivery to the eye using hydrogel iontophoresis
    • etal.
    • Eljarrat-Binstock E, etal. Charged nanoparticles delivery to the eye using hydrogel iontophoresis. J Control Release 2008; 126: 156-561.
    • (2008) J Control Release , vol.126 , pp. 156-561
    • Eljarrat-Binstock, E.1
  • 257
    • 84862826803 scopus 로고    scopus 로고
    • Sustained release micellar carrier systems for iontophoretic transport of dexamethasone across human sclera
    • etal.
    • Chopra P, etal. Sustained release micellar carrier systems for iontophoretic transport of dexamethasone across human sclera. J Control Release 2012; 160: 96-104.
    • (2012) J Control Release , vol.160 , pp. 96-104
    • Chopra, P.1
  • 258
    • 84899481989 scopus 로고    scopus 로고
    • Aciont. (accessed 21 June 2013)
    • Aciont. Visulex® System. 2008. http://www.aciont.com/technologies/ visulex. (accessed 21 June 2013).
    • (2008) Visulex® System
  • 259
    • 79957467372 scopus 로고    scopus 로고
    • Ocular iontophoresis of EGP-437 (dexamethasone phosphate) in dry eye patients: Results of a randomized clinical trial
    • etal.
    • Patane MA, etal. Ocular iontophoresis of EGP-437 (dexamethasone phosphate) in dry eye patients: results of a randomized clinical trial. Clin Ophthalmol 2011; 5: 633-643.
    • (2011) Clin Ophthalmol , vol.5 , pp. 633-643
    • Patane, M.A.1
  • 260
    • 84855320097 scopus 로고    scopus 로고
    • Study investigators. Evaluation of dexamethasone phosphate delivered by ocular iontophoresis for treating noninfectious anterior uveitis
    • etal.
    • Cohen AE, etal. Study investigators. evaluation of dexamethasone phosphate delivered by ocular iontophoresis for treating noninfectious anterior uveitis. Ophthalmology 2012; 119: 66-73.
    • (2012) Ophthalmology , vol.119 , pp. 66-73
    • Cohen, A.E.1
  • 261
    • 0029918482 scopus 로고    scopus 로고
    • Transdermal drug delivery using low-frequency sonophoresis
    • etal.
    • Mitragotri S, etal. Transdermal drug delivery using low-frequency sonophoresis. Pharm Res 1996; 13: 411-420.
    • (1996) Pharm Res , vol.13 , pp. 411-420
    • Mitragotri, S.1
  • 262
    • 78549249985 scopus 로고    scopus 로고
    • Enhancing the transdermal delivery of rigid nanoparticles using the simultaneous application of ultrasound and sodium lauryl sulfate
    • etal.
    • Lopez RF, etal. Enhancing the transdermal delivery of rigid nanoparticles using the simultaneous application of ultrasound and sodium lauryl sulfate. Biomaterials 2011; 32: 933-941.
    • (2011) Biomaterials , vol.32 , pp. 933-941
    • Lopez, R.F.1
  • 263
    • 78650529814 scopus 로고    scopus 로고
    • Transport pathways and enhancement mechanisms within localized and non-localized transport regions in skin treated with low-frequency sonophoresis and sodium lauryl sulfate
    • etal.
    • Polat BE, etal. Transport pathways and enhancement mechanisms within localized and non-localized transport regions in skin treated with low-frequency sonophoresis and sodium lauryl sulfate. J Pharm Sci 2011; 100: 512-529.
    • (2011) J Pharm Sci , vol.100 , pp. 512-529
    • Polat, B.E.1
  • 264
    • 84866714104 scopus 로고    scopus 로고
    • Rapid skin permeabilization by the simultaneous application of dual-frequency, high-intensity ultrasound
    • etal.
    • Schoellhammer CM, etal. Rapid skin permeabilization by the simultaneous application of dual-frequency, high-intensity ultrasound. J Control Release 2012; 163: 154-160.
    • (2012) J Control Release , vol.163 , pp. 154-160
    • Schoellhammer, C.M.1
  • 265
    • 0036019870 scopus 로고    scopus 로고
    • Ocular drug delivery using 20-kHz ultrasound
    • etal.
    • Zderic V, etal. Ocular drug delivery using 20-kHz ultrasound. Ultrasound Med Biol 2002; 28: 823-829.
    • (2002) Ultrasound Med Biol , vol.28 , pp. 823-829
    • Zderic, V.1
  • 266
    • 7444246137 scopus 로고    scopus 로고
    • Ultrasound-Enhanced transcorneal drug delivery
    • etal.
    • Zderic V, etal. Ultrasound-Enhanced transcorneal drug delivery. Cornea 2004; 23: 804-811.
    • (2004) Cornea , vol.23 , pp. 804-811
    • Zderic, V.1
  • 267
    • 4644325089 scopus 로고    scopus 로고
    • Drug delivery into the eye with the use of ultrasound
    • etal.
    • Zderic V, etal. Drug delivery into the eye with the use of ultrasound. J Ultrasound Med 2004; 23: 1349-1359.
    • (2004) J Ultrasound Med , vol.23 , pp. 1349-1359
    • Zderic, V.1
  • 268
    • 78049261849 scopus 로고    scopus 로고
    • Ultrasound-enhanced intrascleral delivery of protein
    • etal.
    • Cheung ACY, etal. Ultrasound-enhanced intrascleral delivery of protein. Int J Pharm 2010; 401: 16-24.
    • (2010) Int J Pharm , vol.401 , pp. 16-24
    • Cheung, A.C.Y.1
  • 269
    • 79958223028 scopus 로고    scopus 로고
    • Ultrasound-mediated transdermal drug delivery: Mechanisms, scope, and emerging trends
    • etal.
    • Polat BE, etal. Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends. J Control Release 2011; 152: 330-348.
    • (2011) J Control Release , vol.152 , pp. 330-348
    • Polat, B.E.1
  • 270
    • 0018404185 scopus 로고
    • Phonophoresis in various diseases of the anterior segment of the eye
    • Tsok RM,. Phonophoresis in various diseases of the anterior segment of the eye. Oftalmol Zh 1979; 34: 73-76.
    • (1979) Oftalmol Zh , vol.34 , pp. 73-76
    • Tsok, R.M.1
  • 271
    • 19244373958 scopus 로고
    • Results of intraocular pharmaco-physical therapy in inflammatory diseases of the cornea
    • etal.
    • Egorov EA, etal. Results of intraocular pharmaco-physical therapy in inflammatory diseases of the cornea. Vestn Oftalmol 1995; 111: 31-34.
    • (1995) Vestn Oftalmol , vol.111 , pp. 31-34
    • Egorov, E.A.1
  • 272
    • 0018338694 scopus 로고
    • Current state and perspectives of further development of phonophoresis of drugs in ophthalmology
    • etal.
    • Marmur RK, etal. Current state and perspectives of further development of phonophoresis of drugs in ophthalmology. Oftalmol Zh 1979; 34: 68-73.
    • (1979) Oftalmol Zh , vol.34 , pp. 68-73
    • Marmur, R.K.1
  • 273
    • 0025584007 scopus 로고
    • Phonophoresis of the proteolytic enzymes lekozim or kollalizin in the combined therapy of eye burns
    • Lakimenko SA, Chalanova RI,. Phonophoresis of the proteolytic enzymes lekozim or kollalizin in the combined therapy of eye burns. Oftalmol Zh 1990; 6: 321-324.
    • (1990) Oftalmol Zh , vol.6 , pp. 321-324
    • Lakimenko, S.A.1    Chalanova, R.I.2
  • 274
    • 0024792087 scopus 로고
    • The use of lekozim phonophoresis for the treatment of eye burns
    • etal.
    • Lakimento SA, etal. The use of lekozim phonophoresis for the treatment of eye burns. Oftalmol Zh 1989; 8: 492-497.
    • (1989) Oftalmol Zh , vol.8 , pp. 492-497
    • Lakimento, S.A.1
  • 275
    • 0033159840 scopus 로고    scopus 로고
    • Effect of superphonoelectrophoresis on chorioretinal dystrophy
    • Gvarishvili EP, Dushin NV,. Effect of superphonoelectrophoresis on chorioretinal dystrophy. Vestn Oftalmol 1999; 115: 19-21.
    • (1999) Vestn Oftalmol , vol.115 , pp. 19-21
    • Gvarishvili, E.P.1    Dushin, N.V.2
  • 276
    • 66749157398 scopus 로고    scopus 로고
    • Acoustic cavitation as an enhancing mechanism of low-frequency sonophoresis for transdermal drug delivery
    • etal.
    • Ueda H, etal. Acoustic cavitation as an enhancing mechanism of low-frequency sonophoresis for transdermal drug delivery. Biol Pharm Bull 2009; 32: 916-920.
    • (2009) Biol Pharm Bull , vol.32 , pp. 916-920
    • Ueda, H.1
  • 277
    • 84872023687 scopus 로고    scopus 로고
    • Nanoparticle delivery enhancement with acoustically activated microbubbles
    • etal.
    • Mullin L, etal. Nanoparticle delivery enhancement with acoustically activated microbubbles. IEEE Trans Ultrason Ferroelectr Freq Control 2013; 60: 65-77.
    • (2013) IEEE Trans Ultrason Ferroelectr Freq Control , vol.60 , pp. 65-77
    • Mullin, L.1
  • 278
    • 80054756038 scopus 로고    scopus 로고
    • In vivo gene transfer into the ocular ciliary muscle mediated by ultrasound and microbubbles
    • etal.
    • Kowalczuk L, etal. In vivo gene transfer into the ocular ciliary muscle mediated by ultrasound and microbubbles. Ultrasound Med Biol 2011; 37: 1814-1827.
    • (2011) Ultrasound Med Biol , vol.37 , pp. 1814-1827
    • Kowalczuk, L.1
  • 279
    • 80051731829 scopus 로고    scopus 로고
    • Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro
    • etal.
    • Lee NG, etal. Sonoporation enhances chemotherapeutic efficacy in retinoblastoma cells in vitro. Invest Ophthalmol Vis Sci 2011; 52: 3868-3873.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 3868-3873
    • Lee, N.G.1
  • 280
    • 33644860216 scopus 로고    scopus 로고
    • Gene transfer to corneal epithelium and keratocytes mediated by ultrasound with microbubbles
    • etal.
    • Sanoda S, etal. Gene transfer to corneal epithelium and keratocytes mediated by ultrasound with microbubbles. Invest Ophthalmol Vis Sci 2006; 47: 558-564.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 558-564
    • Sanoda, S.1
  • 281
    • 80054052815 scopus 로고    scopus 로고
    • Ultrasound-mediated gene transfer into rat retina using micro-bubbles
    • etal.: E-Abstract 5194.
    • Sanoda S, etal. Ultrasound-mediated gene transfer into rat retina using micro-bubbles. Invest Ophthalmol Vis Sci 2005; 46: E-Abstract 5194.
    • (2005) Invest Ophthalmol Vis Sci , vol.46
    • Sanoda, S.1
  • 282
    • 84873807954 scopus 로고    scopus 로고
    • Selective gene transfer to the retina using intravitreal ultrasound irradiation
    • etal.
    • Sanoda S, etal. Selective gene transfer to the retina using intravitreal ultrasound irradiation. J Ophthalmol 2012; 2012: 1-5.
    • (2012) J Ophthalmol , vol.2012 , pp. 1-5
    • Sanoda, S.1
  • 283
    • 23644448692 scopus 로고
    • Die Ionentherapie in der Augenheilkunde
    • Wirtz R,. Die Ionentherapie in der Augenheilkunde. Klin Mbl Augenheilk 1908; 46: 543. Nível Superior
    • (1908) Klin Mbl Augenheilk , vol.46 , pp. 543
    • Wirtz, R.1


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