Design and evaluation of baicalin-containing in situ pH-triggered gelling system for sustained ophthalmic drug delivery

International Journal of Pharmaceutics

Volumn 410, Issue 1-2, 2011, Pages 31-40

  Wu, Haoyun ^a,b   Liu, Zhidong ^a,b   Peng, Junjie ^c   Li, Lin ^a,b   Li, Nan ^a,b   Li, Jiawei ^a,b   Pan, Hao ^c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Baicalin; Carbopol; Hydroxypropylmethylcellulose; In situ gelling system; Sustained ophthalmic delivery

Indexed keywords

BAICALIN; CARBOMER; HYDROXYPROPYLMETHYLCELLULOSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONFOCAL MICROSCOPY; CONFOCAL SCANNING LIGHT MICROSCOPY; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG SCREENING; DRUG STABILITY; FLOW KINETICS; FLOW MEASUREMENT; GAMMA SCINTIGRAPHY; GEL; IN VITRO STUDY; IN VIVO STUDY; MICRODIALYSIS; NONHUMAN; PH; PHYSIOLOGY; PRIORITY JOURNAL; RADIOACTIVITY; STRENGTH; SUSTAINED DRUG RELEASE; SUSTAINED OPHTHALMIC DRUG DELIVERY; SUSTAINED RELEASE FORMULATION;

ACRYLATES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DELAYED-ACTION PREPARATIONS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EXCIPIENTS; FLAVONOIDS; GELS; HYDROGEN-ION CONCENTRATION; METHYLCELLULOSE; MICROSCOPY, CONFOCAL; RABBITS; RHEOLOGY; VISCOSITY;

EID: 79955643091     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.03.007     Document Type: Article

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