Chitosan coated sodium alginate-chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye

European Journal of Pharmaceutical Sciences

Volumn 47, Issue 4, 2012, Pages 678-685

  Nagarwal, Ramesh C ^a   Kumar, Rakesh ^a   Pandit, J K ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

5 FU; Aqueous humor; Chitosan; Nanoparticle; Ocular; Sodium alginate

Indexed keywords

ALGINIC ACID; CHITOSAN; FLUOROURACIL; NANOPARTICLE; STOMACH MUCIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS HUMOR; AREA UNDER THE CURVE; ARTICLE; ATOMIC FORCE MICROSCOPY; CONTROLLED STUDY; CORNEA; CORNEA EDEMA; DIALYSIS MEMBRANE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG HALF LIFE; DRUG SAFETY; DRUG STABILITY; DRUG STORAGE; DRUG TOLERABILITY; EXPERIMENTAL RABBIT; EYE DISEASE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; LIGHT SCATTERING; MALE; MAXIMUM PLASMA CONCENTRATION; MICROBIAL GROWTH; MUCOADHESION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; TIME TO MAXIMUM PLASMA CONCENTRATION; TURBIDITY; VISCOSITY; VITREOUS BODY; ZETA POTENTIAL;

ALGINATES; ANIMALS; AQUEOUS HUMOR; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DRUG DELIVERY SYSTEMS; DRUG STABILITY; FLUOROURACIL; GLUCURONIC ACID; HEXURONIC ACIDS; NANOPARTICLES; OPHTHALMIC SOLUTIONS; PARTICLE SIZE; RABBITS; SWINE; TECHNOLOGY, PHARMACEUTICAL;

EID: 84866499684     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2012.08.008     Document Type: Article

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