메뉴 건너뛰기




Volumn 39, Issue 4, 2013, Pages 508-519

Development of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir

Author keywords

Acyclovir; Entrapment efficiency; Nanostructured lipid carriers; Ocular bioavailability; Ocular drug delivery system; Solid lipid nanoparticles

Indexed keywords

ACICLOVIR; NANOCARRIER; NANOSTRUCTURED LIPID CARRIER; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG;

EID: 84874502028     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2012.665460     Document Type: Article
Times cited : (133)

References (71)
  • 1
    • 0016828838 scopus 로고
    • Editorials: Herpes simplex virus infection-present status of diagnosis and management
    • Nahmias AJ. (1975). Editorials: Herpes simplex virus infection-present status of diagnosis and management. South Med J, 68:1191-1194.
    • (1975) South Med J , vol.68 , pp. 1191-1194
    • Nahmias, A.J.1
  • 2
    • 0035171263 scopus 로고    scopus 로고
    • Herpes simplex virus epidemiology and ocular importance
    • DOI 10.1097/00003226-200101000-00001
    • Liesegang TJ. (2001). Herpes simplex virus epidemiology and ocular importance. Cornea, 20:1-13. (Pubitemid 32038147)
    • (2001) Cornea , vol.20 , Issue.1 , pp. 1-13
    • Liesegang, T.J.1
  • 3
    • 0028233346 scopus 로고
    • Vaccine therapy for ocular herpes simplex virus (HSV) infection: Periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits
    • Nesburn AB, Burke RL, Ghiasi H, Slanina S, Bahri S, Wechsler SL. (1994). Vaccine therapy for ocular herpes simplex virus (HSV) infection: periocular vaccination reduces spontaneous ocular HSV type 1 shedding in latently infected rabbits. J Virol, 68:5084-5092. (Pubitemid 24226576)
    • (1994) Journal of Virology , vol.68 , Issue.8 , pp. 5084-5092
    • Nesburn, A.B.1    Burke, R.L.2    Ghiasi, H.3    Slanina, S.4    Bahri, S.5    Wechsler, S.L.6
  • 4
    • 0024552765 scopus 로고
    • Herpes simplex virus-induced stromal keratitis: Role of T-lymphocyte subsets in immunopathology
    • Newell CK, Martin S, Sendele D, Mercadal CM, Rouse BT. (1989). Herpes simplex virus-induced stromal keratitis: role of T-lymphocyte subsets in immunopathology. J Virol, 63:769-775. (Pubitemid 19057244)
    • (1989) Journal of Virology , vol.63 , Issue.2 , pp. 769-775
    • Newell, C.K.1    Martin, S.2    Sendele, D.3    Mercadal, C.M.4    Rouse, B.T.5
  • 5
    • 0018178561 scopus 로고
    • Acute follicular conjunctivitis and keratoconjunctivitis due to herpes simplex virus in London
    • Darougar S, Hunter PA, Viswalingam M, Gibson JA, Jones BR. (1978). Acute follicular conjunctivitis and keratoconjunctivitis due to herpes simplex virus in London. Br J Ophthalmol, 62:843-849. (Pubitemid 9019024)
    • (1978) British Journal of Ophthalmology , vol.62 , Issue.12 , pp. 843-849
    • Darougar, S.1    Hunter, P.A.2    Viswalingam, M.3
  • 8
    • 66049113709 scopus 로고    scopus 로고
    • Novel nanoparticles made from amphiphilic perfuoroalkyl alpha-cyclodextrin derivatives: Preparation, characterization and application to the transport of acyclovir
    • Ghera BB, Perret F, Chevalier Y, Parrot-Lopez H. (2009). Novel nanoparticles made from amphiphilic perfuoroalkyl alpha-cyclodextrin derivatives: preparation, characterization and application to the transport of acyclovir. Int J Pharm, 375:155-162.
    • (2009) Int J Pharm , vol.375 , pp. 155-162
    • Ghera, B.B.1    Perret, F.2    Chevalier, Y.3    Parrot-Lopez, H.4
  • 9
    • 0032158915 scopus 로고    scopus 로고
    • Transport of L-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line, Caco-2
    • de Vrueh RL, Smith PL, Lee CP. (1998). Transport of L-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line, Caco-2. J Pharmacol Exp Ter, 286:1166-1170. (Pubitemid 29135525)
    • (1998) Journal of Pharmacology and Experimental Therapeutics , vol.286 , Issue.3 , pp. 1166-1170
    • De Vrueh, R.L.A.1    Smith, P.L.2    Lee, C.-P.3
  • 13
    • 22344445908 scopus 로고    scopus 로고
    • Managing ophthalmic herpes zoster in primary care
    • Zaal M, Opstelten W. (2005) Managing ophthalmic herpes zoster in primary care, BMJ-Bri Med J, 331: 147-151. (Pubitemid 41003176)
    • (2005) British Medical Journal , vol.331 , Issue.7509 , pp. 147-151
    • Opstelten, W.1    Zaal, M.J.W.2
  • 15
    • 0033977825 scopus 로고    scopus 로고
    • Acyclovir-containing liposomes for potential ocular delivery Corneal penetration and absorption
    • DOI 10.1016/S0168-3659(99)00192-3, PII S0168365999001923
    • Law SL, Huang KJ, Chiang CH. (2000). Acyclovir-containing liposomes for potential ocular delivery. Corneal penetration and absorption. J Control Release, 63:135-140. (Pubitemid 30046949)
    • (2000) Journal of Controlled Release , vol.63 , Issue.1-2 , pp. 135-140
    • Law, S.L.1    Huang, K.J.2    Chiang, C.H.3
  • 16
    • 67650635130 scopus 로고    scopus 로고
    • Development of mucoadhesive microspheres of acyclovir with enhanced bioavailability
    • Tao Y, Lu Y, Sun Y, Gu B, Lu W, Pan J. (2009). Development of mucoadhesive microspheres of acyclovir with enhanced bioavailability. Int J Pharm, 378:30-36.
    • (2009) Int J Pharm , vol.378 , pp. 30-36
    • Tao, Y.1    Lu, Y.2    Sun, Y.3    Gu, B.4    Lu, W.5    Pan, J.6
  • 17
    • 37249061100 scopus 로고    scopus 로고
    • Effect of chitosan, benzalkonium chloride and ethylenediaminetetraacetic acid on permeation of acyclovir across isolated rabbit cornea
    • DOI 10.1016/j.ijpharm.2007.08.017, PII S037851730700659X
    • Majumdar S, Hippalgaonkar K, Repka MA. (2008). Efect of chitosan, benzalkonium chloride and ethylenediaminetetraacetic acid on permeation of acyclovir across isolated rabbit cornea. Int J Pharm, 348:175-178. (Pubitemid 350266247)
    • (2008) International Journal of Pharmaceutics , vol.348 , Issue.1-2 , pp. 175-178
    • Majumdar, S.1    Hippalgaonkar, K.2    Repka, M.A.3
  • 18
    • 43049183001 scopus 로고    scopus 로고
    • Synthesis and characterization of cross-linked malonylchitosan microspheres for controlled release of acyclovir
    • Stulzer HK, Lacerda, Tagliari MP, Silva MA, Fávere VT, Laranjeira MC. (2008) Synthesis and characterization of cross-linked malonylchitosan microspheres for controlled release of acyclovir. Carbohydr Polymer, 73: 490-497.
    • (2008) Carbohydr Polymer , vol.73 , pp. 490-497
    • Stulzer, H.K.1    Lacerda Tagliari, M.P.2    Silva, M.A.3    Fávere, V.T.4    Laranjeira, M.C.5
  • 19
    • 0035946615 scopus 로고    scopus 로고
    • Solid lipid nanoparticles: Production, characterization and applications
    • DOI 10.1016/S0169-409X(01)00105-3, PII S0169409X01001053
    • Mehnert W, Mäder K. (2001). Solid lipid nanoparticles: production, characterization and applications. Adv Drug Deliv Rev, 47:165-196. (Pubitemid 32324113)
    • (2001) Advanced Drug Delivery Reviews , vol.47 , Issue.2-3 , pp. 165-196
    • Mehnert, W.1    Mader, K.2
  • 20
    • 77956161610 scopus 로고    scopus 로고
    • Solid lipid nanoparticles for ocular drug delivery
    • Seyfoddin A, Shaw J, Al-Kassas R. (2010). Solid lipid nanoparticles for ocular drug delivery. Drug Deliv, 17:467-489.
    • (2010) Drug Deliv , vol.17 , pp. 467-489
    • Seyfoddin, A.1    Shaw, J.2    Al-Kassas, R.3
  • 21
    • 0035999073 scopus 로고    scopus 로고
    • Ocular preparations: The formulation approach
    • DOI 10.1081/DDC-120003445
    • Kaur IP, Kanwar M. (2002). Ocular preparations: the formulation approach. Drug Dev Ind Pharm, 28:473-493. (Pubitemid 34680549)
    • (2002) Drug Development and Industrial Pharmacy , vol.28 , Issue.5 , pp. 473-493
    • Kaur, I.P.1    Kanwar, M.2
  • 22
    • 52449132114 scopus 로고    scopus 로고
    • Development of efective ocular preparations of antifungal agents
    • Kaur IP, Rana C, Singh H. (2008). Development of efective ocular preparations of antifungal agents. J Ocul Pharmacol Ter, 24:481-493.
    • (2008) J Ocul Pharmacol ter , vol.24 , pp. 481-493
    • Kaur, I.P.1    Rana, C.2    Singh, H.3
  • 24
    • 0030944482 scopus 로고    scopus 로고
    • Peptide-loaded solid lipid nanoparticles (SLN): Influence of production parameters
    • DOI 10.1016/S0378-5173(97)04885-0, PII S0378517397048850
    • Almeida A J, Runge S, Müller RH. (1997) Peptide-loaded solid lipid nanoparticles (SLN): Infuence of production parameters, Int J Pharm, 149: 255-265. (Pubitemid 27193412)
    • (1997) International Journal of Pharmaceutics , vol.149 , Issue.2 , pp. 255-265
    • Almeida, A.J.1    Runge, S.2    Muller, R.H.3
  • 25
    • 33947128784 scopus 로고    scopus 로고
    • Investigation of surface-modified solid lipid nanocontainers formulated with a heterolipid-templated homolipid
    • DOI 10.1016/j.ijpharm.2006.10.032, PII S0378517306008969
    • Attama AA, Müller-Goymann CC. (2007). Investigation of surface-modifed solid lipid nanocontainers formulated with a heterolipid-templated homolipid. Int J Pharm, 334:179-189. (Pubitemid 46400318)
    • (2007) International Journal of Pharmaceutics , vol.334 , Issue.1-2 , pp. 179-189
    • Attama, A.A.1    Muller-Goymann, C.C.2
  • 26
    • 51649130848 scopus 로고    scopus 로고
    • A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers
    • Nie. X, LiKong J, Li N, Ju C y, Pan WS. (2008) A controlled-release ocular delivery system for ibuprofen based on nanostructured lipid carriers. Int J Pharm, 363: 177-182.
    • (2008) Int J Pharm , vol.363 , pp. 177-182
    • Nie, X.1    Likong, J.2    Li, N.3    Ju, C.Y.4    Pan, W.S.5
  • 27
    • 26244444984 scopus 로고    scopus 로고
    • Preparation and characterization of stearic acid nanostructured lipid carriers by solvent diffusion method in an aqueous system
    • DOI 10.1016/j.colsurfb.2005.08.005, PII S092777650500247X
    • Hu FQ, Jiang SP, Du YZ, Yuan H, Ye YQ, Zeng S. (2005). Preparation and characterization of stearic acid nanostructured lipid carriers by solvent difusion method in an aqueous system. Colloids Surf B Biointerfaces, 45:167-173. (Pubitemid 41415646)
    • (2005) Colloids and Surfaces B: Biointerfaces , vol.45 , Issue.3-4 , pp. 167-173
    • Hu, F.-Q.1    Jiang, S.-P.2    Du, Y.-Z.3    Yuan, H.4    Ye, Y.-Q.5    Zeng, S.6
  • 28
    • 71549165819 scopus 로고    scopus 로고
    • Incorporation of liquid lipid in lipid nanoparticles for ocular drug delivery enhancement
    • Shen J, Sun M, Ping Q, Ying Z, Liu W. (2010) Incorporation of liquid lipid in lipid nanoparticles for ocular drug delivery enhancement, Nanotech, 21: 1-10.
    • (2010) Nanotech , vol.21 , pp. 1-10
    • Shen, J.1    Sun, M.2    Ping, Q.3    Ying, Z.4    Liu, W.5
  • 29
    • 34547663284 scopus 로고    scopus 로고
    • Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: Characterization and ability to bind the pEGFP-plasmid
    • DOI 10.1016/j.ejpb.2007.02.006, PII S093964110700029X
    • Vighi E, Ruozi B, Montanari M, Battini R, Leo E. (2007). Re-dispersible cationic solid lipid nanoparticles (SLNs) freeze-dried without cryoprotectors: characterization and ability to bind the pEGFP-plasmid. Eur J Pharm Biopharm, 67:320-328. (Pubitemid 47211893)
    • (2007) European Journal of Pharmaceutics and Biopharmaceutics , vol.67 , Issue.2 , pp. 320-328
    • Vighi, E.1    Ruozi, B.2    Montanari, M.3    Battini, R.4    Leo, E.5
  • 30
    • 0037453180 scopus 로고    scopus 로고
    • Preparation and purification of cationic solid lipid nanospheres - Effects on particle size, physical stability and cell toxicity
    • DOI 10.1016/S0378-5173(02)00688-9
    • Heydenreich AV, Westmeier R, Pedersen N, Poulsen HS, Kristensen HG. (2003). Preparation and purifcation of cationic solid lipid nanospheres-efects on particle size, physical stability and cell toxicity. Int J Pharm, 254:83-87. (Pubitemid 36259816)
    • (2003) International Journal of Pharmaceutics , vol.254 , Issue.1 , pp. 83-87
    • Heydenreich, A.V.1    Westmeier, R.2    Pedersen, N.3    Poulsen, H.S.4    Kristensen, H.G.5
  • 31
    • 52949112251 scopus 로고    scopus 로고
    • Lipid nanoparticles as vehicles for topical psoralen delivery: Solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC)
    • Fang JY, Fang CL, Liu CH, Su YH. (2008). Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC). Eur J Pharm Biopharm, 70:633-640.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 633-640
    • Fang, J.Y.1    Fang, C.L.2    Liu, C.H.3    Su, Y.H.4
  • 32
    • 84874453028 scopus 로고    scopus 로고
    • A potential new therapeutic system for glaucoma: Solid lipid nanoparticles containing methazolamide
    • Li R, Jiang S, Liu D, Bi X, Wang F, Zhang Q, Xu Q, (2010) A potential new therapeutic system for glaucoma: solid lipid nanoparticles containing methazolamide, J Microencapsul, 1-8.
    • (2010) J Microencapsul , pp. 1-8
    • Li, R.1    Jiang, S.2    Liu, D.3    Bi, X.4    Wang, F.5    Zhang, Q.6    Xu, Q.7
  • 33
    • 79953234715 scopus 로고    scopus 로고
    • Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo
    • Liu Z, Zhang X, Wu H, Li J, Shu L, Liu R et al. (2011). Preparation and evaluation of solid lipid nanoparticles of baicalin for ocular drug delivery system in vitro and in vivo. Drug Dev Ind Pharm, 37:475-481.
    • (2011) Drug Dev Ind Pharm , vol.37 , pp. 475-481
    • Liu, Z.1    Zhang, X.2    Wu, H.3    Li, J.4    Shu, L.5    Liu, R.6
  • 34
    • 0030604042 scopus 로고    scopus 로고
    • Evaluation of ocular permeation enhancers: In vitro effects on corneal transport of four β-blockers, and in vitro/in vivo toxic activity
    • DOI 10.1016/0378-5173(96)04663-7
    • Saettone M F, Chetoni P, Cerbai R, Mazzanti G, Braghiroli L. (1996) Evaluation of ocular permeation enhancers: In vitro efects on corneal transport of four [beta]-blockers, and in vitro/in vivo toxic activity. Int J Pharm, 142: 103-113. (Pubitemid 26343835)
    • (1996) International Journal of Pharmaceutics , vol.142 , Issue.1 , pp. 103-113
    • Saettone, M.F.1    Chetoni, P.2    Cerbai, R.3    Mazzanti, G.4    Braghiroli, L.5
  • 35
    • 0037203690 scopus 로고    scopus 로고
    • Increased corneal hydration induced by potential ocular penetration enhancers: Assessment by differential scanning calorimetry (DSC) and by desiccation
    • DOI 10.1016/S0378-5173(01)00907-3, PII S0378517301009073
    • Monti D, Chetoni P, Burgalassi S, Najarro M, Saettone MF. (2002). Increased corneal hydration induced by potential ocular penetration enhancers: assessment by diferential scanning calorimetry (DSC) and by desiccation. Int J Pharm, 232:139-147. (Pubitemid 34076759)
    • (2002) International Journal of Pharmaceutics , vol.232 , Issue.1-2 , pp. 139-147
    • Monti, D.1    Chetoni, P.2    Burgalassi, S.3    Najarro, M.4    Saettone, M.F.5
  • 36
    • 0021052458 scopus 로고
    • Corneal penetration behavior of β-blocking agents. I: Physicochemical factors
    • Schoenwald RD, Huang HS. (1983). Corneal penetration behavior of beta-blocking agents I: Physiochemical factors. J Pharm Sci, 72:1266-1272. (Pubitemid 14229733)
    • (1983) Journal of Pharmaceutical Sciences , vol.72 , Issue.11 , pp. 1266-1272
    • Schoenwald, R.D.1    Huang, H.S.2
  • 38
    • 64149094878 scopus 로고    scopus 로고
    • Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery
    • Lv Q, Yu A, Xi Y, Li H, Song Z, Cui J et al. (2009). Development and evaluation of penciclovir-loaded solid lipid nanoparticles for topical delivery. Int J Pharm, 372:191-198.
    • (2009) Int J Pharm , vol.372 , pp. 191-198
    • Lv, Q.1    Yu, A.2    Xi, Y.3    Li, H.4    Song, Z.5    Cui, J.6
  • 39
    • 0037433842 scopus 로고    scopus 로고
    • Preparation of solid lipid nanoparticles by a solvent emulsification-diffusion technique
    • DOI 10.1016/S0378-5173(03)00135-2
    • Trotta M, Debernardi F, Caputo O. (2003). Preparation of solid lipid nanoparticles by a solvent emulsifcation-difusion technique. Int J Pharm, 257:153-160. (Pubitemid 36507041)
    • (2003) International Journal of Pharmaceutics , vol.257 , Issue.1-2 , pp. 153-160
    • Trotta, M.1    Debernardi, F.2    Caputo, O.3
  • 40
    • 66049142567 scopus 로고    scopus 로고
    • Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin
    • Subedi RK, Kang KW, Choi HK. (2009). Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin. Eur J Pharm Sci, 37:508-513.
    • (2009) Eur J Pharm Sci , vol.37 , pp. 508-513
    • Subedi, R.K.1    Kang, K.W.2    Choi, H.K.3
  • 41
    • 17644410411 scopus 로고    scopus 로고
    • Why should researchers report the confidence interval in modern research?
    • Attia A. (2005) Why should researchers report the confdence interval in modern research?, Mid East Ferti Soci J, 10: 78-81. (Pubitemid 40559472)
    • (2005) Middle East Fertility Society Journal , vol.10 , Issue.1 , pp. 78-81
    • Attia, A.1
  • 42
    • 33845314297 scopus 로고    scopus 로고
    • Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery
    • DOI 10.1016/j.ijpharm.2006.08.007, PII S0378517306006582
    • Liu J, Hu W, Chen H, Ni Q, Xu H, Yang X. (2007). Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery. Int J Pharm, 328:191-195. (Pubitemid 44880576)
    • (2007) International Journal of Pharmaceutics , vol.328 , Issue.2 , pp. 191-195
    • Liu, J.1    Hu, W.2    Chen, H.3    Ni, Q.4    Xu, H.5    Yang, X.6
  • 43
    • 34247536269 scopus 로고    scopus 로고
    • Preparation and characterization of a self-emulsifying pellet formulation
    • DOI 10.1016/j.ejpb.2006.11.015, PII S093964110600333X
    • Abdalla A, Mäder K. (2007). Preparation and characterization of a self-emulsifying pellet formulation. Eur J Pharm Biopharm, 66:220-226. (Pubitemid 46654779)
    • (2007) European Journal of Pharmaceutics and Biopharmaceutics , vol.66 , Issue.2 , pp. 220-226
    • Abdalla, A.1    Mader, K.2
  • 44
    • 0028299388 scopus 로고
    • Automated high-performance liquid chromatographic method for the determination of acyclovir in plasma
    • DOI 10.1016/0021-9673(94)80496-6
    • Swart KJ, Hundt HK, Groenewald AM. (1994). Automated high-performance liquid chromatographic method for the determination of acyclovir in plasma. J Chromatogr A, 663:65-69. (Pubitemid 24075211)
    • (1994) Journal of Chromatography A , vol.663 , Issue.1 , pp. 65-69
    • Swart, K.J.1    Hundt, H.K.L.2    Groenewald, A.M.3
  • 45
    • 33746537717 scopus 로고    scopus 로고
    • Polymorphic behaviour of Compritol®888 ATO as bulk lipid and as SLN and NLC
    • DOI 10.1080/02652040600612439, PII ML7Q574PH727XG10
    • Souto EB, Mehnert W, Müller RH. (2006). Polymorphic behaviour of Compritol888 ATO as bulk lipid and as SLN and NLC. J Microencapsul, 23:417-433. (Pubitemid 44132550)
    • (2006) Journal of Microencapsulation , vol.23 , Issue.4 , pp. 417-433
    • Souto, E.B.1    Mehnert, W.2    Muller, R.H.3
  • 46
    • 53949111819 scopus 로고    scopus 로고
    • Cyclosporine A loaded SLNs: Evaluation of cellular uptake and corneal cytotoxicity
    • Gokce EH, Sandri G, Bonferoni MC, Rossi S, Ferrari F, Güneri T et al. (2008). Cyclosporine A loaded SLNs: evaluation of cellular uptake and corneal cytotoxicity. Int J Pharm, 364:76-86.
    • (2008) Int J Pharm , vol.364 , pp. 76-86
    • Gokce, E.H.1    Sandri, G.2    Bonferoni, M.C.3    Rossi, S.4    Ferrari, F.5    Güneri, T.6
  • 47
    • 72449183701 scopus 로고    scopus 로고
    • Cyclosporine a-loaded solid lipid nanoparticles: Ocular tolerance and in vivo drug release in rabbit eyes
    • Gökçe EH, Sandri G, Egrilmez S, Bonferoni MC, Güneri T, Caramella C. (2009). Cyclosporine a-loaded solid lipid nanoparticles: ocular tolerance and in vivo drug release in rabbit eyes. Curr Eye Res, 34:996-1003.
    • (2009) Curr Eye Res , vol.34 , pp. 996-1003
    • Gökçe, E.H.1    Sandri, G.2    Egrilmez, S.3    Bonferoni, M.C.4    Güneri, T.5    Caramella, C.6
  • 48
    • 0031960962 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery - Drug release and release mechanism
    • DOI 10.1016/S0939-6411(97)00150-1, PII S0939641197001501
    • zur Mühlen A, Schwarz C, Mehnert W. (1998). Solid lipid nanoparticles (SLN) for controlled drug delivery-drug release and release mechanism. Eur J Pharm Biopharm, 45:149-155. (Pubitemid 28167741)
    • (1998) European Journal of Pharmaceutics and Biopharmaceutics , vol.45 , Issue.2 , pp. 149-155
    • Zur Muhlen, A.1    Schwarz, C.2    Mehnert, W.3
  • 49
    • 0032982005 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery. II. Drug incorporation and physicochemical characterization
    • Schwarz C, Mehnert W. (1999). Solid lipid nanoparticles (SLN) for controlled drug delivery. II. Drug incorporation and physicochemical characterization. J Microencapsul, 16:205-213. (Pubitemid 29099602)
    • (1999) Journal of Microencapsulation , vol.16 , Issue.2 , pp. 205-213
    • Schwarz, C.1    Mehnert, W.2
  • 51
    • 0345390953 scopus 로고    scopus 로고
    • Correlation between long-term stability of solid lipid nanoparticles (SLN(TM)) and crystallinity of the lipid phase
    • DOI 10.1016/S0939-6411(98)00074-5, PII S0939641198000745
    • Freitas C, Müller RH. (1999). Correlation between long-term stability of solid lipid nanoparticles (SLN) and crystallinity of the lipid phase. Eur J Pharm Biopharm, 47:125-132. (Pubitemid 29185115)
    • (1999) European Journal of Pharmaceutics and Biopharmaceutics , vol.47 , Issue.2 , pp. 125-132
    • Freitas, C.1    Muller, R.H.2
  • 52
    • 0342350239 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) based on binary mixtures of liquid and solid lipids: A (1) H-NMR study
    • Jenning V, Mäder K, Gohla SH. (2000). Solid lipid nanoparticles (SLN) based on binary mixtures of liquid and solid lipids: a (1) H-NMR study. Int J Pharm, 205:15-21.
    • (2000) Int J Pharm , vol.205 , pp. 15-21
    • Jenning, V.1    Mäder, K.2    Gohla, S.H.3
  • 53
    • 79954567170 scopus 로고    scopus 로고
    • Enhanced delivery of lopinavir to the CNS using Compritol®-based solid lipid nanoparticles
    • Alex A, Paul W, Chacko A, Sharma C P. (2011) Enhanced delivery of lopinavir to the CNS using Compritol®-based solid lipid nanoparticles, Terap Del, 2: 25-35.
    • (2011) Terap Del , vol.2 , pp. 25-35
    • Alex, A.1    Paul, W.2    Chacko, A.3    Sharma, C.P.4
  • 54
    • 67349203156 scopus 로고    scopus 로고
    • Efect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery
    • Paliwal R, Rai S, Vaidya B, Khatri K, Goyal AK, Mishra N et al. (2009). Efect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery. Nanomedicine, 5:184-191.
    • (2009) Nanomedicine , vol.5 , pp. 184-191
    • Paliwal, R.1    Rai, S.2    Vaidya, B.3    Khatri, K.4    Goyal, A.K.5    Mishra, N.6
  • 56
    • 34547913461 scopus 로고    scopus 로고
    • Stability of lipid excipients in solid lipid nanoparticles
    • DOI 10.1016/j.addr.2007.04.004, PII S0169409X07000385, Lipid Nanoparticles: Recent Advances
    • Radomska-Soukharev A. (2007). Stability of lipid excipients in solid lipid nanoparticles. Adv Drug Deliv Rev, 59:411-418. (Pubitemid 47259223)
    • (2007) Advanced Drug Delivery Reviews , vol.59 , Issue.6 , pp. 411-418
    • Radomska-Soukharev, A.1
  • 57
    • 0031006729 scopus 로고    scopus 로고
    • Investigation of the gel formation of phospholipid-stabilized solid lipid nanoparticles
    • DOI 10.1016/S0378-5173(97)04890-4, PII S0378517397048904
    • Westesen K, Siekmann B, (1997)Investigation of the gel formation of phospholipid-stabilized solid lipid nanoparticles, Int J Pharm, 151: 35-45. (Pubitemid 27212302)
    • (1997) International Journal of Pharmaceutics , vol.151 , Issue.1 , pp. 35-45
    • Westesen, K.1    Siekmann, B.2
  • 59
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art
    • DOI 10.1016/S0939-6411(00)00087-4, PII S0939641100000874
    • Müller RH, Mäder K, Gohla S. (2000). Solid lipid nanoparticles (SLN) for controlled drug delivery-a review of the state of the art. Eur J Pharm Biopharm, 50:161-177. (Pubitemid 30326695)
    • (2000) European Journal of Pharmaceutics and Biopharmaceutics , vol.50 , Issue.1 , pp. 161-177
    • Muller, R.H.1    Mader, K.2    Gohla, S.3
  • 60
    • 1242338847 scopus 로고    scopus 로고
    • Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy
    • DOI 10.1016/j.jconrel.2003.11.012
    • Jores K, Mehnert W, Drechsler M, Bunjes H, Johann C, Mäder K. (2004). Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, feld-fow fractionation and transmission electron microscopy. J Control Release, 95:217-227. (Pubitemid 38230037)
    • (2004) Journal of Controlled Release , vol.95 , Issue.2 , pp. 217-227
    • Jores, K.1    Mehnert, W.2    Drechsler, M.3    Bunjes, H.4    Johann, C.5    Mader, K.6
  • 61
    • 0037006918 scopus 로고    scopus 로고
    • Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin
    • DOI 10.1016/S0378-5173(02)00009-1, PII S0378517302000091
    • Gwak HS, Chun IK. (2002). Efect of vehicles and penetration enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. Int J Pharm, 236:57-64. (Pubitemid 34219373)
    • (2002) International Journal of Pharmaceutics , vol.236 , Issue.1-2 , pp. 57-64
    • Gwak, H.S.1    Chun, I.K.2
  • 62
    • 44849087456 scopus 로고    scopus 로고
    • Design and evaluation of self-microemulsifying drug delivery system (SMEDDS) of tacrolimus
    • Borhade V, Nair H, Hegde D. (2008). Design and evaluation of self-microemulsifying drug delivery system (SMEDDS) of tacrolimus. AAPS PharmSciTech, 9:13-21.
    • (2008) AAPS PharmSciTech , vol.9 , pp. 13-21
    • Borhade, V.1    Nair, H.2    Hegde, D.3
  • 63
    • 0030817849 scopus 로고    scopus 로고
    • Freeze-drying of drug-free and drug-loaded solid lipid nanoparticles (SLN)
    • DOI 10.1016/S0378-5173(97)00222-6, PII S0378517397002226
    • Schwarz C, Mehnert W. (1997). Freeze-drying of drug-free and drug-loaded solid lipid nanoparticles (SLN). Int J Pharm, 157:171-179. (Pubitemid 27471169)
    • (1997) International Journal of Pharmaceutics , vol.157 , Issue.2 , pp. 171-179
    • Schwarz, C.1    Mehnert, W.2
  • 64
    • 59649111692 scopus 로고    scopus 로고
    • Short-and long-term stability study of lyophilized solid lipid nanoparticles for gene therapy
    • del Pozo-Rodríguez A, Solinís MA, Gascón AR, Pedraz JL. (2009). Short-and long-term stability study of lyophilized solid lipid nanoparticles for gene therapy. Eur J Pharm Biopharm, 71:181-189.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 181-189
    • Del Pozo-Rodríguez, A.1    Solinís, M.A.2    Gascón, A.R.3    Pedraz, J.L.4
  • 66
    • 0030604042 scopus 로고    scopus 로고
    • Evaluation of ocular permeation enhancers: In vitro effects on corneal transport of four β-blockers, and in vitro/in vivo toxic activity
    • DOI 10.1016/0378-5173(96)04663-7
    • Saettone M F, Chetoni P, Cerbai R, Mazzanti G, Braghiroli L. (1996) Evaluation of ocular permeation enhancers: In vitro efects on corneal transport of four β-blockers, and in vitro/in vivo toxic activity, Int J Pharm, 142: 103-113. (Pubitemid 26343835)
    • (1996) International Journal of Pharmaceutics , vol.142 , Issue.1 , pp. 103-113
    • Saettone, M.F.1    Chetoni, P.2    Cerbai, R.3    Mazzanti, G.4    Braghiroli, L.5
  • 67
    • 77952670687 scopus 로고    scopus 로고
    • Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers
    • Patlolla RR, Chougule M, Patel AR, Jackson T, Tata PN, Singh M. (2010). Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers. J Control Release, 144:233-241.
    • (2010) J Control Release , vol.144 , pp. 233-241
    • Patlolla, R.R.1    Chougule, M.2    Patel, A.R.3    Jackson, T.4    Tata, P.N.5    Singh, M.6
  • 69
    • 0041632201 scopus 로고    scopus 로고
    • The effect of spray drying solutions of bendroflumethiazide/polyethylene glycol on the physicochemical properties of the resultant materials
    • DOI 10.1016/S0378-5173(03)00338-7
    • Corrigan DO, Healy AM, Corrigan OI. (2003). Te efect of spray drying solutions of bendrofumethiazide/polyethylene glycol on the physicochemical properties of the resultant materials. Int J Pharm, 262:125-137. (Pubitemid 36966700)
    • (2003) International Journal of Pharmaceutics , vol.262 , Issue.1-2 , pp. 125-137
    • Corrigan, D.O.1    Healy, A.M.2    Corrigan, O.I.3
  • 70
    • 71549165819 scopus 로고    scopus 로고
    • Incorporation of liquid lipid in lipid nanoparticles for ocular drug delivery enhancement
    • Shen J, Sun M, Ping Q, Ying Z, Liu W. (2010). Incorporation of liquid lipid in lipid nanoparticles for ocular drug delivery enhancement. Nanotechnology, 21:025101.
    • (2010) Nanotechnology , vol.21 , pp. 025101
    • Shen, J.1    Sun, M.2    Ping, Q.3    Ying, Z.4    Liu, W.5
  • 71
    • 79952252661 scopus 로고    scopus 로고
    • Design and evaluation of controlled-release niosomes and discomes for naltrexone hydrochloride ocular delivery
    • Abdelkader H, Ismail S, Kamal A, Alany RG. (2011). Design and evaluation of controlled-release niosomes and discomes for naltrexone hydrochloride ocular delivery. J Pharm Sci, 100:1833-1846.
    • (2011) J Pharm Sci , vol.100 , pp. 1833-1846
    • Abdelkader, H.1    Ismail, S.2    Kamal, A.3    Alany, R.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.