Development of O/W nanoemulsions for ophthalmic administration of timolol

International Journal of Pharmaceutics

Volumn 440, Issue 2, 2013, Pages 126-134

  Gallarate, M ^a   Chirio, D ^a   Bussano, R ^a   Peira, E ^a   Battaglia, L ^a   Baratta, F ^a   Trotta, M ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Corneal irritation; Ion pair; Nanoemulsions; Ocular administration; Timolol

Indexed keywords

CHITOSAN; POLYMER; TIMOLOL; WATER OIL CREAM;

ANIMAL EXPERIMENT; ANIMAL MODEL; AQUEOUS SOLUTION; ARTICLE; CHEMICAL INTERACTION; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA OPACITY; DRUG ACCUMULATION; DRUG FORMULATION; DRUG PENETRATION; EPITHELIUM CELL; EX VIVO STUDY; EYE IRRITATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPOPHILICITY; MALE; NANOEMULSION; NONHUMAN; OSMOLARITY; PH; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RABBIT; SURFACE TENSION; VISCOSITY; ZETA POTENTIAL;

ADMINISTRATION, OPHTHALMIC; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BIOLOGICAL AVAILABILITY; CHITOSAN; CORNEAL OPACITY; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIONS; NANOTECHNOLOGY; RABBITS; SODIUM HYDROXIDE; SUCCINATES; TIMOLOL;

EID: 84872339222     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.10.015     Document Type: Article

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