Mucoadhesive nanoparticles for prolonged ocular delivery of natamycin: In vitro and pharmacokinetics studies

International Journal of Pharmaceutics

Volumn 432, Issue 1-2, 2012, Pages 105-112

  Bhatta, R S ^a   Chandasana, H ^b   Chhonker, Y S ^a   Rathi, C ^b   Kumar, D ^a   Mitra, K ^a   Shukla, P K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b National Institute of Pharmaceutical Education and Research (NIPER)   (India)

Author keywords

Chitosan; Lecithin; Nanoparticles; Natamycin; Ocular pharmacokinetic

Indexed keywords

CHITOSAN MUCOADHESIVE NANOPARTICLE; LECITHIN MUCOADHESIVE NANOPARTICLE; MUCIN; NANOCARRIER; NATAMET; NATAMYCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIFUNGAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DOSE REGIMEN; EXPERIMENTAL RABBIT; IN VITRO STUDY; MALE; MEAN RESIDENCE TIME; MINIMUM INHIBITORY CONCENTRATION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN BINDING; SIMULATION; SLOW DRUG RELEASE; ZETA POTENTIAL;

ADMINISTRATION, OPHTHALMIC; ANIMALS; ANTIFUNGAL AGENTS; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CHITOSAN; DRUG CARRIERS; LECITHINS; MALE; MICROBIAL SENSITIVITY TESTS; MUCINS; NANOPARTICLES; NATAMYCIN; PARTICLE SIZE; RABBITS;

EID: 84861600703     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.04.060     Document Type: Article

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