In Vivo Gene Transfer into the Ocular Ciliary Muscle Mediated by Ultrasound and Microbubbles

Ultrasound in Medicine and Biology

Volumn 37, Issue 11, 2011, Pages 1814-1827

  Kowalczuk, Laura ^a,b   Boudinet, Michèle ^c   El Sanharawi, Mohamed ^a,b   Touchard, Elodie ^a,b   Naud, Marie Christine ^a,b   Saïed, Amena ^c   Jeanny, Jean Claude ^a,b   Behar Cohen, Francine ^a,b,d   Laugier, Pascal ^c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d HÔTEL DIEU   (France)

Author keywords

Ciliary muscle; Eye; Microbubble; Non viral gene therapy; Sonoporation; Targeted protein delivery; Ultrasound

Indexed keywords

CILIARY MUSCLE; EYE; MICRO-BUBBLE; NON-VIRAL GENE THERAPY; SONOPORATION; TARGETED PROTEIN DELIVERY;

ENZYME ACTIVITY; GENE TRANSFER; GENES; LENSES; PROTEINS; ULTRASONIC APPLICATIONS; ULTRASONICS;

MUSCLE;

BETA GALACTOSIDASE; GREEN FLUORESCENT PROTEIN; LUCIFERASE; PLASMID DNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CILIARY MUSCLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; FEASIBILITY STUDY; FEMALE; GENETIC TRANSFECTION; HISTOCHEMISTRY; IN VIVO GENE TRANSFER; LENS; LUMINESCENCE; MICROBUBBLE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RADIATION EXPOSURE; RAT; REPORTER GENE; TEMPERATURE; ULTRASOUND; ULTRASOUND ASSISTED GENE DELIVERY SYSTEM; ULTRASOUND TRANSDUCER;

ANALYSIS OF VARIANCE; ANIMALS; BETA-GALACTOSIDASE; CILIARY BODY; EYE DISEASES; FEASIBILITY STUDIES; FEMALE; GENE TRANSFER TECHNIQUES; GREEN FLUORESCENT PROTEINS; IN SITU NICK-END LABELING; LUCIFERASES; MICROBUBBLES; PLASMIDS; RATS; RATS, INBRED LEW; SONICATION; STATISTICS, NONPARAMETRIC; TRANSFECTION;

EID: 80054756038     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2011.07.010     Document Type: Article

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