Mucoadhesive effect of thiolated PEG stearate and its modified NLC for ocular drug delivery

Journal of Controlled Release

Volumn 137, Issue 3, 2009, Pages 217-223

  Shen, Jie ^a   Wang, Yu ^a   Ping, Qineng ^a   Xiao, Yanyu ^a   Huang, Xin ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Mucoadhesive; Nanostructured lipid carrier; Polyethylene glycol stearate; Precorneal retention; Thiomers

Indexed keywords

CONCENTRATION OF; CYCLOSPORINE A; DISULPHIDE BONDS; FREE THIOL GROUP; INTERMEDIATE FORMATION; MUCIN PARTICLES; MUCOADHESIVE; MUCOADHESIVE PROPERTIES; NANO PARTICULATES; NANOCARRIERS; NANOSTRUCTURED LIPID CARRIER; NANOSTRUCTURED LIPID CARRIERS; OCULAR DRUG DELIVERY; OCULAR DRUG DELIVERY SYSTEMS; PRECORNEAL RETENTION; RETENTION TIME; THIOMERS;

CONTROLLED DRUG DELIVERY; EMULSIFICATION; ETHYLENE GLYCOL; POLYETHYLENE OXIDES; POLYETHYLENES; SIMULATED ANNEALING; SURFACE ACTIVE AGENTS; THERMOPLASTICS; ZETA POTENTIAL;

POLYETHYLENE GLYCOLS;

CARBONYL DERIVATIVE; CYCLOSPORIN A; CYSTEINE; DISULFIDE; LIPID; MACROGOL STEARATE; MUCIN; NANOCARRIER; NANOMATERIAL; NONIONIC SURFACTANT; THIOL DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORNEA; DISULFIDE BOND; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; DRUG SYNTHESIS; MALE; MELTING POINT; MUCOADHESION; NANOEMULSION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RABBIT; STRUCTURE ANALYSIS; ZETA POTENTIAL;

ADHESIVENESS; ANIMALS; CYCLOSPORINE; CYSTEINE; LIPIDS; MALE; MUCINS; NANOSTRUCTURES; OPHTHALMIC SOLUTIONS; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RABBITS; SULFHYDRYL COMPOUNDS; SWINE; TEARS; VISCOSITY;

EID: 67649101315     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.04.021     Document Type: Article

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