Development of a poloxamer analogs/carbopol-based in situ gelling and mucoadhesive ophthalmic delivery system for puerarin

International Journal of Pharmaceutics

Volumn 337, Issue 1-2, 2007, Pages 178-187

  Qi, Hongyi ^a   Chen, Wenwen ^a   Huang, Chunyan ^a   Li, Li ^b   Chen, Chuming ^a   Li, Wenmin ^a   Wu, Chunjie ^a  

^a CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Carbopol; In situ gelling; Mucoadhesive; Ophthalmic delivery system; Poloxamer; Puerarin

Indexed keywords

ADHESIVE AGENT; CARBOMER; CP 1342; CP 980; GELLING AGENT; P 188; P 407; POLOXAMER; PUERARIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG ELIMINATION; DRUG RELEASE; EVALUATION; EYE; GEL; HEAT SENSITIVITY; HUMAN; HYSTERESIS; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR PRESSURE; LACRIMAL FLUID; MUCOSA; NONHUMAN; PRIORITY JOURNAL; SHEAR RATE; SHEAR STRESS;

ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DELAYED-ACTION PREPARATIONS; DIFFUSION; DRUG CARRIERS; DRUG COMPOUNDING; EYE; GELS; INTRAOCULAR PRESSURE; ISOFLAVONES; MUCOUS MEMBRANE; OPHTHALMIC SOLUTIONS; POLOXAMER; POLYVINYLS; RABBITS; RHEOLOGY; SHEAR STRENGTH; SOLUBILITY; TEARS; TEMPERATURE; VASODILATOR AGENTS; VISCOSITY;

EID: 34248571833     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.12.038     Document Type: Article

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