Microscopic and spectroscopic evaluation of novel PLGA-chitosan Nanoplexes as an ocular delivery system

Colloids and Surfaces B: Biointerfaces

Volumn 82, Issue 2, 2011, Pages 397-403

  Jain, Gaurav K ^a   Pathan, Shadab A ^a   Akhter, Sohail ^a   Jayabalan, Nirmal ^b   Talegaonkar, Sushma ^a   Khar, Roop K ^a   Ahmad, Farhan J ^a  

^a HAMDARD UNIVERSITY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Chitosan; Confocal microscopy; Nanoplexes; Ocular drug delivery; PLGA

Indexed keywords

DRUG CARRIER; ENCAPSULATION EFFICIENCY; EPITHELIAL CELLS; EX-VIVO; IN-VIVO; IONOTROPIC GELATION; MEAN DIAMETER; NANOPLEXES; OCULAR DELIVERY; OCULAR DRUG DELIVERY; PLGA; SEM; SPECTROFLUORIMETRY; SPECTROSCOPIC EVALUATION; SURFACE EXPOSURE; TEM; TIGHT JUNCTIONS; UPTAKE MECHANISM;

CHITIN; CHITOSAN; COAGULATION; CONFOCAL MICROSCOPY; DRUG DELIVERY; ENCAPSULATION; GELATION; MOLECULAR BIOLOGY; SULFUR COMPOUNDS;

MULTILAYERS;

CHITOSAN; DRUG CARRIER; NANOPARTICLE; POLYGLACTIN; POLYGLACTIN CHITOSAN NANOPLEX; RHODAMINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORNEA; CORNEA EPITHELIUM; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; EPITHELIUM CELL; EX VIVO STUDY; EXPERIMENTAL RABBIT; EYE; GELATION; IN VIVO STUDY; IONOTROPIC GELATION; MORPHOLOGY; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PH; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SHEAR STRESS; SPECTROFLUOROMETRY; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY; VISCOSITY; ZETA POTENTIAL;

ANIMALS; CHITOSAN; DRUG DELIVERY SYSTEMS; EYE; FLUORESCENT DYES; HUMANS; LACTIC ACID; MATERIALS TESTING; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; NANOTECHNOLOGY; PARTICLE SIZE; POLYGLYCOLIC ACID; RABBITS; RHODAMINES; SPECTROPHOTOMETRY; TIME FACTORS;

ORYCTOLAGUS CUNICULUS;

EID: 78649442663     PISSN: 09277765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2010.09.010     Document Type: Article

References (32)

1. Bourlais C.L., Acar L., Zia H., Sado P.A., Needham T., Leverge R. Prog. Retin. Eye Res. 1998, 17:33.
2. Lee V.H.L., Robinson J.R. J. Ocul. Pharmacol. 1986, 2:67.
3. Urtti A. Adv. Drug Deliv. Rev. 2006, 58:1131.
4. Gaudana R., Jwala J., Boddu S.H., Mitra A.K. Pharm. Res. 2009, 26:1197.
5. Calvo P., Alonso M.J., Vila-Jato J.L., Robinson J.R. J. Pharm. Pharmacol. 1996, 48:1147.
6. Cai X., Conley S., Naash M. Vis. Res. 2008, 48:319.
7. Wadhwa S., Paliwal R., Paliwal S.R., Vyas S.P. Curr. Pharm. Des. 2009, 15:2724.
8. Vandervoort J., Ludwig A. Nanomedicine 2007, 2:11.
9. Bu H.Z., Gukasyan H.J., Goulet L., Lou X.J., Xiang C., Koudriakova T. Curr. Drug Metab. 2007, 8:91.
10. Vargas A., Pegaz B., Debefve E., Konan-Kouakou Y., Lange N., Ballini J.P., van den Bergh H., Gurny R., Delie F. Int. J. Pharm. 2004, 286:131-145.
11. Bejjani R.A., BenEzra D., Cohen H., Rieger J., Andrieu C., Jeanny J.C., Gollomb G., Behar-Cohen F.F. Mol. Vis. 2005, 11:124.
12. Dillen K., Vandervoort J., Ludwig A. J. Contr. Release 2005, 101:369.
13. Mandal B., Halder K.K., Dey S.K., Bhoumik M., Debnath M.C., Ghosh L.K. Pharmazie 2009, 64:445.
14. Gupta H., Aqil M., Khar R.K., Bhatnagar A., Mittal G. Nanomedicine 2010, 6:324.
15. Vega E., Egea M.A., Valls O., Espina M., García M.L. J. Pharm. Sci. 2006, 95:2393.
16. Araújo J., Vega E., Lopes C., Egea M.A., Garcia M.L., Souto E.B. Colloids Surf. B: Biointerf. 2009, 72:48.
17. Vega E., Gamisans F., García M.L., Chauvet A., Lacoulonche F., Egea M.A. J. Pharm. Sci. 2008, 97:5306.
18. Davies N.M., Farr S.J., Hadgraft J., Kellaway I.W. Pharm. Res. 1992, 9:1137.
19. Paolicelli P., dela Fuente M., Sánchez A., Seijo B., Alonso M.J. Expert Opin. Drug Deliv. 2009, 6:239.
20. Badawi A.A., El-Laithy H.M., El Qidra R.K., El Mofty H., El dally M. Arch. Pharm. Res. 2008, 31:1040.
21. Enríquez de Salamanca A., Diebold Y., Calonge M., García-Vazquez C., Callejo S., Vila A., Alonso M.J. Invest. Ophthalmol. Vis. Sci. 2006, 47:1416.
22. Alonso M.J., Sánchez A.J. Pharm. Pharmacol. 2003, 55:1451.
23. Calvo P., Vila-Jato J.L., Alonso M.J. Int. J. Pharm. 1997, 153:41.
24. Jain G.K., Jain N., Pathan S.A., Akhter S., Talegaonkar S., Chander P., Khar R.K., Ahmad F.J. J. Pharm. Biomed. Anal. 2010, 52:110-113.
25. Motwani S.K., Chopra S., Talegaonkar S., Kohli K., Ahmad F.J., Khar R.K. Eur. J. Pharm. Biopharm. 2008, 68:513.
26. Qaddoumi M.G., Gukasyan H.J., Davda J., Labhasetwar V., Kim K.J., Lee V.H. Mol. Vis. 2003, 9:559.
27. Qaddoumi M.G., Ueda H., Yang J., Davda J., Labhasetwar V., Lee V.H. Pharm. Res. 2004, 21:641.
28. DeCampos A., Sanchez A., Alonso M.J. Int. J. Pharm. 2001, 224:159.
29. Dodane V., Khan M.A., Merwin J.R. Int. J. Pharm. 1999, 182:21.
30. Koch M.A., Dodane V., Khan M.A., Merwin J.R. Scanning 1998, 20:262.
31. Calvo P., Thomas C., Alonso M.J., Vila-Jato J.L., Robinson J.R. Int. J. Pharm. 1994, 103:283.
32. Wood R.W., Li V.H., Kreuter R., Robinson J.R. Int. J. Pharm. 1985, 23:175.