Cancer suppression by the chromosome custodians, BRCA1 and BRCA2

Science

Volumn 343, Issue 6178, 2014, Pages 1470-1475

  Venkitaraman, Ashok R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; DNA HELICASE; NUCLEOPROTEIN; PHOSPHOPEPTIDE; RAD51 PROTEIN; RNA POLYMERASE II;

BIOCHEMICAL COMPOSITION; CANCER; CHROMOSOME; MOLECULAR ANALYSIS; PROTEIN;

ANEUPLOIDY; BREAST CANCER; CANCER GROWTH; CANCER INHIBITION; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL CYCLE; CELL PROLIFERATION; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOMAL INSTABILITY; CHROMOSOME; CHROMOSOME DUPLICATION; CHROMOSOME SEGREGATION; CLINICAL FEATURE; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; GENE EXPRESSION; GENE MUTATION; HUMAN; KINETOCHORE MICROTUBULE; M PHASE CELL CYCLE CHECKPOINT; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; RING FINGER MOTIF; STRUCTURAL CHROMOSOME ABERRATION; TISSUE SPECIFICITY; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; BREAST TUMOR; CHROMOSOME ABERRATION; FEMALE; GENETICS; GERMLINE MUTATION; PATHOLOGY; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOGENESIS; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATIONS; FEMALE; GENES, TUMOR SUPPRESSOR; GERM-LINE MUTATION; HUMANS; MODELS, GENETIC; ORGAN SPECIFICITY;

EID: 84896940791     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1252230     Document Type: Review

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