Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers

Nature

Volumn 451, Issue 7182, 2008, Pages 1116-1120

  Sakai, Wataru ^a   Swisher, Elizabeth M ^b,c   Karlan, Beth Y ^d   Agarwal, Mukesh K ^e   Higgins, Jake ^c   Friedman, Cynthia ^a   Villegas, Emily ^a   Jacquemont, Céline ^a   Farrugia, Daniel J ^e   Couch, Fergus J ^e   Urban, Nicole ^a   Taniguchi, Toshiyasu ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d CEDARS SINAI MEDICAL CENTER   (United States)

^e MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AG 14361; CISPLATIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; POLY(ADENOSINE DIPHOSPHATE RIBOSE); UNCLASSIFIED DRUG;

CANCER; CHEMOTHERAPY; DRUG RESISTANCE; INHIBITOR; MUTATION; PLATINUM; TUMOR;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; GENE FUNCTION; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN FUNCTION; RECURRENT CANCER; SEQUENCE ANALYSIS; TUMOR SUPPRESSOR GENE;

EID: 39849106300     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06633     Document Type: Article

References (39)