BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a Brca1 transgene

Oncogene

Volumn 18, Issue 55, 1999, Pages 7900-7907

  Snouwaert, John N ^a   Gowen, Lori C ^a   Latour, Anne M ^a   Mohn, Amy R ^a   Xiao, Andrew ^b   Dibiase, Lauren ^a   Koller, Beverly H ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

BRCA1 proteins; DNA repair; ES cells; Homologous recombination; Non homologous recombination

Indexed keywords

BRCA1 PROTEIN; DNA; DOUBLE STRANDED DNA; NUCLEAR PROTEIN; PHOSPHOPROTEIN;

ANIMAL CELL; ARTICLE; BREAST CANCER; CONTROLLED STUDY; DNA INTEGRATION; DNA REPAIR; ELECTROPORATION; EMBRYO; GENE MUTATION; GENE TARGETING; GENETIC RECOMBINATION; HUMAN; MOUSE; NONHUMAN; ONCOGENE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN DEFICIENCY; STEM CELL; TRANSGENE; TUMOR SUPPRESSOR GENE;

ANIMALIA; MURINAE;

EID: 0033590171     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203334     Document Type: Article

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