Abnormal cytokinesis in cells deficient in the breast cancer susceptibility protein BRCA2

Science

Volumn 306, Issue 5697, 2004, Pages 876-879

  Daniels, Matthew J ^a   Wang, Yunmei ^a   Lee, MiYoung ^a   Venkitaraman, Ashok R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; PROTEINS; RNA; TUMORS;

CELL DIVISION; CHROMOSOMAL INSTABILITY; CHROMOSOME NUMBERS; CYTOKINESIS;

CELLS;

BRCA2 PROTEIN; MYOSIN II;

BIOLOGY;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CELL DIVISION; CELL KINETICS; CELL SEPARATION; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOKINESIS; FIBROBLAST; GENE DISRUPTION; HEREDITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DEFICIENCY; RNA INTERFERENCE;

ANAPHASE; ANEUPLOIDY; ANIMALS; BRCA2 PROTEIN; CELL DIVISION; CELL LINE, TUMOR; CELL NUCLEUS; CELLS, CULTURED; EMBRYO; GENE TARGETING; GENES, BRCA2; HELA CELLS; HUMANS; MICE; MITOSIS; MYOSIN TYPE II; RNA, SMALL INTERFERING;

ANIMALIA; MURINAE;

EID: 7444222440     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1102574     Document Type: Article

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21. We thank J. Pines and L.K. Ferrigno (Cambridge) for helpful comments on this paper. M.J.D. received an AstraZeneca studentship through the Cambridge University M.B., Ph.D. program. Work in A.R.V.'s laboratory is supported by Cancer Research UK and the Medical Research Council.