-
1
-
-
46249131123
-
Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
-
Bennardo, N., A. Cheng, N. Huang, and J.M. Stark. 2008. Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet. 4:e1000110. http://dx.doi.org/10.1371/journal.pgen .1000110
-
(2008)
PLoS Genet.
, vol.4
-
-
Bennardo, N.1
Cheng, A.2
Huang, N.3
Stark, J.M.4
-
2
-
-
3142608985
-
Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains
-
Botuyan, M.V., Y. Nominé, X. Yu, N. Juranic, S. Macura, J. Chen, and G. Mer. 2004. Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains. Structure. 12:1137-1146. http://dx.doi.org/10.1016/j.str.2004.06.002
-
(2004)
Structure.
, vol.12
, pp. 1137-1146
-
-
Botuyan, M.V.1
Nominé, Y.2
Yu, X.3
Juranic, N.4
Macura, S.5
Chen, J.6
Mer, G.7
-
3
-
-
43149118369
-
Cell cycle-dependent complex formation of BRCA1
-
Chen, L., C.J. Nievera, A.Y. Lee, and X. Wu. 2008. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. J. Biol. Chem. 283:7713-7720. http://dx.doi.org/10.1074/ jbc.M710245200
-
(2008)
CtIP.MRN is important for DNA double-strand break repair. J. Biol. Chem.
, vol.283
, pp. 7713-7720
-
-
Chen, L.1
Nievera, C.J.2
Lee, A.Y.3
Wu, X.4
-
4
-
-
17644375501
-
Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency
-
Chen, P.L., F. Liu, S. Cai, X. Lin, A. Li, Y. Chen, B. Gu, E.Y. Lee, and W.H. Lee. 2005. Inactivation of CtIP leads to early embryonic lethality mediated by G1 restraint and to tumorigenesis by haploid insufficiency. Mol. Cell. Biol. 25:3535-3542. http://dx.doi.org/10.1128/MCB.25.9.3535-3542.2005
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3535-3542
-
-
Chen, P.L.1
Liu, F.2
Cai, S.3
Lin, X.4
Li, A.5
Chen, Y.6
Gu, B.7
Lee, E.Y.8
Lee, W.H.9
-
5
-
-
28644435986
-
CtIP, a candidate tumor susceptibility gene is a team player with luminaries
-
Chinnadurai, G. 2006. CtIP, a candidate tumor susceptibility gene is a team player with luminaries. Biochim. Biophys. Acta. 1765:67-73.
-
(2006)
Biochim. Biophys. Acta.
, vol.1765
, pp. 67-73
-
-
Chinnadurai, G.1
-
6
-
-
2542489188
-
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
-
Clapperton, J.A., I.A. Manke, D.M. Lowery, T. Ho, L.F. Haire, M.B. Yaffe, and S.J. Smerdon. 2004. Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer. Nat. Struct. Mol. Biol. 11:512-518. http://dx.doi.org/10.1038/nsmb775
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 512-518
-
-
Clapperton, J.A.1
Manke, I.A.2
Lowery, D.M.3
Ho, T.4
Haire, L.F.5
Yaffe, M.B.6
Smerdon, S.J.7
-
7
-
-
84876877091
-
A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice
-
Escribano-Díaz, C., A. Orthwein, A. Fradet-Turcotte, M. Xing, J.T. Young, J. Tkác̊, M.A. Cook, A.P. Rosebrock, M. Munro, M.D. Canny, et al. 2013. A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol. Cell. 49:872-883. http://dx.doi.org/10.1016/j.molcel.2013.01.001
-
(2013)
Mol. Cell.
, vol.49
, pp. 872-883
-
-
Escribano-Díaz, C.1
Orthwein, A.2
Fradet-Turcotte, A.3
Xing, M.4
Young, J.T.5
Tkác̊, J.6
Cook, M.A.7
Rosebrock, A.P.8
Munro, M.9
Canny, M.D.10
-
8
-
-
29944434644
-
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
-
Greenberg, R.A., B. Sobhian, S. Pathania, S.B. Cantor, Y. Nakatani, and D.M. Livingston. 2006. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev. 20:34-46. http://dx.doi.org/10.1101/gad.1381306
-
(2006)
Genes Dev.
, vol.20
, pp. 34-46
-
-
Greenberg, R.A.1
Sobhian, B.2
Pathania, S.3
Cantor, S.B.4
Nakatani, Y.5
Livingston, D.M.6
-
9
-
-
0030981170
-
Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation
-
Hakem, R., J.L. de la Pompa, A. Elia, J. Potter, and T.W. Mak. 1997. Partial rescue of Brca1 (5-6) early embryonic lethality by p53 or p21 null mutation. Nat. Genet. 16:298-302. http://dx.doi.org/10.1038/ng0797-298
-
(1997)
Nat. Genet.
, vol.16
, pp. 298-302
-
-
Hakem, R.1
de la Pompa, J.L.2
Elia, A.3
Potter, J.4
Mak, T.W.5
-
10
-
-
58149289464
-
Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA
-
Hartsuiker, E., M.J. Neale, and A.M. Carr. 2009. Distinct requirements for the Rad32(Mre11) nuclease and Ctp1(CtIP) in the removal of covalently bound topoisomerase I and II from DNA. Mol. Cell. 33:117-123. http://dx.doi.org/10.1016/j.molcel.2008.11.021
-
(2009)
Mol. Cell.
, vol.33
, pp. 117-123
-
-
Hartsuiker, E.1
Neale, M.J.2
Carr, A.M.3
-
11
-
-
75149189204
-
BRCA1 and its toolbox for the maintenance of genome integrity
-
Huen, M.S., S.M. Sy, and J. Chen. 2010. BRCA1 and its toolbox for the maintenance of genome integrity. Nat. Rev. Mol. Cell Biol. 11:138-148. http://dx.doi.org/10.1038/nrm2831
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 138-148
-
-
Huen, M.S.1
Sy, S.M.2
Chen, J.3
-
12
-
-
34547655427
-
CCDC98 is a BRCA1-BRCT domainbinding protein involved in the DNA damage response
-
Kim, H., J. Huang, and J. Chen. 2007. CCDC98 is a BRCA1-BRCT domainbinding protein involved in the DNA damage response. Nat. Struct. Mol. Biol. 14:710-715. http://dx.doi.org/10.1038/nsmb1277
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 710-715
-
-
Kim, H.1
Huang, J.2
Chen, J.3
-
13
-
-
34548401682
-
Saccharomyces cerevisiae Sae2-and Tel1-dependent single-strand DNA formation at DNA break promotes microhomologymediated end joining
-
Lee, K., and S.E. Lee. 2007. Saccharomyces cerevisiae Sae2-and Tel1-dependent single-strand DNA formation at DNA break promotes microhomologymediated end joining. Genetics. 176:2003-2014. http://dx.doi.org/10.1534/genetics.107.076539
-
(2007)
Genetics.
, vol.176
, pp. 2003-2014
-
-
Lee, K.1
Lee, S.E.2
-
14
-
-
84866608818
-
Links between genome integrity and BRCA1 tumor suppression
-
Li, M.L., and R.A. Greenberg. 2012. Links between genome integrity and BRCA1 tumor suppression. Trends Biochem. Sci. 37:418-424. http://dx.doi.org/10.1016/j.tibs.2012.06.007
-
(2012)
Trends Biochem. Sci.
, vol.37
, pp. 418-424
-
-
Li, M.L.1
Greenberg, R.A.2
-
15
-
-
34948872046
-
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
-
Limbo, O., C. Chahwan, Y. Yamada, R.A. de Bruin, C. Wittenberg, and P. Russell. 2007. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell. 28:134-146. http://dx.doi.org/10.1016/j.molcel.2007.09.009
-
(2007)
Mol. Cell.
, vol.28
, pp. 134-146
-
-
Limbo, O.1
Chahwan, C.2
Yamada, Y.3
de Bruin, R.A.4
Wittenberg, C.5
Russell, P.6
-
16
-
-
0029784528
-
Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development
-
Liu, C.-Y., A. Flesken-Nikitin, S. Li, Y. Zeng, and W.-H. Lee. 1996. Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development. Genes Dev. 10:1835-1843. http://dx.doi.org/10.1101/gad.10.14.1835
-
(1996)
Genes Dev.
, vol.10
, pp. 1835-1843
-
-
Liu, C.-Y.1
Flesken-Nikitin, A.2
Li, S.3
Zeng, Y.4
Lee, W.-H.5
-
17
-
-
34547662882
-
CCDC98 targets BRCA1 to DNA damage sites
-
Liu, Z., J. Wu, and X. Yu. 2007. CCDC98 targets BRCA1 to DNA damage sites. Nat. Struct. Mol. Biol. 14:716-720. http://dx.doi.org/10.1038/nsmb1279
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 716-720
-
-
Liu, Z.1
Wu, J.2
Yu, X.3
-
18
-
-
0030924656
-
Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos
-
Ludwig, T., D.L. Chapman, V.E. Papaioannou, and A. Efstratiadis. 1997. Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos. Genes Dev. 11:1226-1241. http://dx.doi.org/10.1101/gad.11.10.1226
-
(1997)
Genes Dev.
, vol.11
, pp. 1226-1241
-
-
Ludwig, T.1
Chapman, D.L.2
Papaioannou, V.E.3
Efstratiadis, A.4
-
19
-
-
0030759699
-
A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2
-
McKee, A.H., and N. Kleckner. 1997. A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics. 146:797-816.
-
(1997)
Genetics.
, vol.146
, pp. 797-816
-
-
McKee, A.H.1
Kleckner, N.2
-
20
-
-
54849404458
-
MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
-
McVey, M., and S.E. Lee. 2008. MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends Genet. 24:529-538. http://dx.doi.org/10.1016/j.tig.2008.08.007
-
(2008)
Trends Genet.
, vol.24
, pp. 529-538
-
-
McVey, M.1
Lee, S.E.2
-
21
-
-
53649104599
-
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
-
Mimitou, E.P., and L.S. Symington. 2008. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature. 455:770-774. http://dx.doi.org/10.1038/nature07312
-
(2008)
Nature.
, vol.455
, pp. 770-774
-
-
Mimitou, E.P.1
Symington, L.S.2
-
22
-
-
77649131406
-
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
-
Moynahan, M.E., and M. Jasin. 2010. Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis. Nat. Rev. Mol. Cell Biol. 11:196-207. http://dx.doi.org/10.1038/nrm2851
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 196-207
-
-
Moynahan, M.E.1
Jasin, M.2
-
23
-
-
0033213392
-
Brca1 controls homology-directed DNA repair
-
Moynahan, M.E., J.W. Chiu, B.H. Koller, and M. Jasin. 1999. Brca1 controls homology-directed DNA repair. Mol. Cell. 4:511-518. http://dx.doi.org/10.1016/S1097-2765(00)80202-6
-
(1999)
Mol. Cell.
, vol.4
, pp. 511-518
-
-
Moynahan, M.E.1
Chiu, J.W.2
Koller, B.H.3
Jasin, M.4
-
24
-
-
0035874894
-
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation
-
Moynahan, M.E., T.Y. Cui, and M. Jasin. 2001a. Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutation. Cancer Res. 61:4842-4850.
-
(2001)
Cancer Res.
, vol.61
, pp. 4842-4850
-
-
Moynahan, M.E.1
Cui, T.Y.2
Jasin, M.3
-
25
-
-
0035099044
-
BRCA2 is required for homology-directed repair of chromosomal breaks
-
Moynahan, M.E., A.J. Pierce, and M. Jasin. 2001b. BRCA2 is required for homology-directed repair of chromosomal breaks. Mol. Cell. 7:263-272. http://dx.doi.org/10.1016/S1097-2765(01)00174-5
-
(2001)
Mol. Cell.
, vol.7
, pp. 263-272
-
-
Moynahan, M.E.1
Pierce, A.J.2
Jasin, M.3
-
26
-
-
76749157216
-
Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair
-
Nakamura, K., T. Kogame, H. Oshiumi, A. Shinohara, Y. Sumitomo, K. Agama, Y. Pommier, K.M. Tsutsui, K. Tsutsui, E. Hartsuiker, et al. 2010. Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair. PLoS Genet. 6:e1000828. http://dx.doi.org/10.1371/journal.pgen.1000828
-
(2010)
PLoS Genet.
, vol.6
-
-
Nakamura, K.1
Kogame, T.2
Oshiumi, H.3
Shinohara, A.4
Sumitomo, Y.5
Agama, K.6
Pommier, Y.7
Tsutsui, K.M.8
Tsutsui, K.9
Hartsuiker, E.10
-
27
-
-
78649805560
-
Mre11-Rad50-Xrs2 and Sae2 promote 5 strand resection of DNA double-strand breaks
-
Nicolette, M.L., K. Lee, Z. Guo, M. Rani, J.M. Chow, S.E. Lee, and T.T. Paull. 2010. Mre11-Rad50-Xrs2 and Sae2 promote 5 strand resection of DNA double-strand breaks. Nat. Struct. Mol. Biol. 17:1478-1485. http://dx.doi.org/10.1038/nsmb.1957
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1478-1485
-
-
Nicolette, M.L.1
Lee, K.2
Guo, Z.3
Rani, M.4
Chow, J.M.5
Lee, S.E.6
Paull, T.T.7
-
28
-
-
77956302112
-
Mechanism of the ATP-dependent DNA endresection machinery from Saccharomyces cerevisiae
-
Niu, H., W.H. Chung, Z. Zhu, Y. Kwon, W. Zhao, P. Chi, R. Prakash, C. Seong, D. Liu, L. Lu, et al. 2010. Mechanism of the ATP-dependent DNA endresection machinery from Saccharomyces cerevisiae. Nature. 467:108-111. http://dx.doi.org/10.1038/nature09318
-
(2010)
Nature.
, vol.467
, pp. 108-111
-
-
Niu, H.1
Chung, W.H.2
Zhu, Z.3
Kwon, Y.4
Zhao, W.5
Chi, P.6
Prakash, R.7
Seong, C.8
Liu, D.9
Lu, L.10
-
29
-
-
35348821296
-
A backup DNA repair pathway moves to the forefront
-
Nussenzweig, A., and M.C. Nussenzweig. 2007. A backup DNA repair pathway moves to the forefront. Cell. 131:223-225. http://dx.doi.org/10.1016/j.cell.2007.10.005
-
(2007)
Cell.
, vol.131
, pp. 223-225
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
30
-
-
37149043618
-
A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination
-
Penkner, A., Z. Portik-Dobos, L. Tang, R. Schnabel, M. Novatchkova, V. Jantsch, and J. Loidl. 2007. A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination. EMBO J. 26:5071-5082. http://dx.doi.org/10.1038/sj.emboj.7601916
-
(2007)
EMBO J.
, vol.26
, pp. 5071-5082
-
-
Penkner, A.1
Portik, Z.2
Tang, L.3
Schnabel, R.4
Novatchkova, M.5
Jantsch, V.6
Loidl, J.7
-
31
-
-
80052609660
-
Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair
-
Peterson, S.E., Y. Li, B.T. Chait, M.E. Gottesman, R. Baer, and J. Gautier. 2011. Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair. J. Cell Biol. 194:705-720. http://dx.doi.org/10.1083/jcb.201103103
-
(2011)
J. Cell Biol.
, vol.194
, pp. 705-720
-
-
Peterson, S.E.1
Li, Y.2
Chait, B.T.3
Gottesman, M.E.4
Baer, R.5
Gautier, J.6
-
32
-
-
0035893363
-
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
-
Pierce, A.J., P. Hu, M. Han, N. Ellis, and M. Jasin. 2001. Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells. Genes Dev. 15:3237-3242. http://dx.doi.org/10.1101/gad.946401
-
(2001)
Genes Dev.
, vol.15
, pp. 3237-3242
-
-
Pierce, A.J.1
Hu, P.2
Han, M.3
Ellis, N.4
Jasin, M.5
-
33
-
-
0030811331
-
Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae
-
Prinz, S., A. Amon, and F. Klein. 1997. Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics. 146:781-795.
-
(1997)
Genetics.
, vol.146
, pp. 781-795
-
-
Prinz, S.1
Amon, A.2
Klein, F.3
-
34
-
-
58549098527
-
E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks
-
Reid, L.J., R. Shakya, A.P. Modi, M. Lokshin, J.-T. Cheng, M. Jasin, R. Baer, and T. Ludwig. 2008. E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc. Natl. Acad. Sci. USA. 105:20876-20881. http://dx.doi.org/10.1073/pnas.0811203106
-
(2008)
Proc. Natl. Acad. Sci. USA.
, vol.105
, pp. 20876-20881
-
-
Reid, L.J.1
Shakya, R.2
Modi, A.P.3
Lokshin, M.4
Cheng, J.-T.5
Jasin, M.6
Baer, R.7
Ludwig, T.8
-
35
-
-
84555196106
-
BRCA1 and BRCA2: different roles in a common pathway of genome protection
-
Roy, R., J. Chun, and S.N. Powell. 2012. BRCA1 and BRCA2: different roles in a common pathway of genome protection. Nat. Rev. Cancer. 12:68-78. http://dx.doi.org/10.1038/nrc3181
-
(2012)
Nat. Rev. Cancer.
, vol.12
, pp. 68-78
-
-
Roy, R.1
Chun, J.2
Powell, S.N.3
-
36
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori, A.A., C. Lukas, J. Coates, M. Mistrik, S. Fu, J. Bartek, R. Baer, J. Lukas, and S.P. Jackson. 2007. Human CtIP promotes DNA end resection. Nature. 450:509-514. http://dx.doi.org/10.1038/nature06337
-
(2007)
Nature.
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
37
-
-
33744947315
-
BRCA1 promotes induction of ssDNA by ionizing radiation
-
Schlegel, B.P., F.M. Jodelka, and R. Nunez. 2006. BRCA1 promotes induction of ssDNA by ionizing radiation. Cancer Res. 66:5181-5189. http://dx.doi.org/10.1158/0008-5472.CAN-05-3209
-
(2006)
Cancer Res.
, vol.66
, pp. 5181-5189
-
-
Schlegel, B.P.1
Jodelka, F.M.2
Nunez, R.3
-
38
-
-
0025075831
-
An expression vector system for stable expression of oncogenes
-
Schuermann, M. 1990. An expression vector system for stable expression of oncogenes. Nucleic Acids Res. 18:4945-4946. http://dx.doi.org/10.1093/nar/18.16.4945
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 4945-4946
-
-
Schuermann, M.1
-
39
-
-
80055092789
-
BRCT phosphoprotein recognition, but not E3 ligase activity, is essential for BRCA1 tumor suppression
-
Shakya, R., L.J. Reid, C.R. Reczek, F. Cole, D. Egli, C.-S. Lin, D.G. de Rooij, S. Hirsch, R. Kandasamy, J.B. Hicks, et al. 2011. BRCT phosphoprotein recognition, but not E3 ligase activity, is essential for BRCA1 tumor suppression. Science. 334:525-528. http://dx.doi.org/10.1126/science.1209909
-
(2011)
Science.
, vol.334
, pp. 525-528
-
-
Shakya, R.1
Reid, L.J.2
Reczek, C.R.3
Cole, F.4
Egli, D.5
Lin, C.-S.6
de Rooij, D.G.7
Hirsch, S.8
Kandasamy, R.9
Hicks, J.B.10
-
40
-
-
2342484423
-
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling
-
Shiozaki, E.N., L. Gu, N. Yan, and Y. Shi. 2004. Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling. Mol. Cell. 14:405-412. http://dx.doi.org/10.1016/S1097-2765 (04)00238-2
-
(2004)
Mol. Cell.
, vol.14
, pp. 405-412
-
-
Shiozaki, E.N.1
Gu, L.2
Yan, N.3
Shi, Y.4
-
41
-
-
0033590171
-
BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene
-
Snouwaert, J.N., L.C. Gowen, A.M. Latour, A.R. Mohn, A. Xiao, L. Di Biase, and B.H. Koller. 1999. BRCA1 deficient embryonic stem cells display a decreased homologous recombination frequency and an increased frequency of non-homologous recombination that is corrected by expression of a brca1 transgene. Oncogene. 18:7900-7907. http://dx.doi.org/10.1038/sj.onc.1203334
-
(1999)
Oncogene.
, vol.18
, pp. 7900-7907
-
-
Snouwaert, J.N.1
Gowen, L.C.2
Latour, A.M.3
Mohn, A.R.4
Xiao, A.5
Di Biase, L.6
Koller, B.H.7
-
42
-
-
33751252292
-
Direct observation of individual endogenous protein complexes in situ by proximity ligation
-
Söderberg, O., M. Gullberg, M. Jarvius, K. Ridderstrale, K.J. Leuchowius, J. Jarvius, K. Wester, P. Hydbring, F. Bahram, L.G. Larsson, and U. Landegren. 2006. Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat. Methods. 3:995-1000. http://dx.doi.org/10.1038/nmeth947
-
(2006)
Nat. Methods.
, vol.3
, pp. 995-1000
-
-
Söderberg, O.1
Gullberg, M.2
Jarvius, M.3
Ridderstrale, K.4
Leuchowius, K.J.5
Jarvius, J.6
Wester, K.7
Hydbring, P.8
Bahram, F.9
Larsson, L.G.10
Landegren, U.11
-
43
-
-
6344234817
-
Genetic steps of mammalian homologous repair with distinct mutagenic consequences
-
Stark, J.M., A.J. Pierce, J. Oh, A. Pastink, and M. Jasin. 2004. Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol. Cell. Biol. 24:9305-9316. http://dx.doi.org/10.1128/MCB.24.21.9305-9316.2004
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9305-9316
-
-
Stark, J.M.1
Pierce, A.J.2
Oh, J.3
Pastink, A.4
Jasin, M.5
-
44
-
-
80755187806
-
Double-strand break end resection and repair pathway choice
-
Symington, L.S., and J. Gautier. 2011. Double-strand break end resection and repair pathway choice. Annu. Rev. Genet. 45:247-271. http://dx.doi.org/10.1146/annurev-genet-110410-132435
-
(2011)
Annu. Rev. Genet.
, vol.45
, pp. 247-271
-
-
Symington, L.S.1
Gautier, J.2
-
45
-
-
37149054791
-
A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene
-
Uanschou, C., T. Siwiec, A. Pedrosa-Harand, C. Kerzendorfer, E. Sanchez-Moran, M. Novatchkova, S. Akimcheva, A. Woglar, F. Klein, and P. Schlögelhofer. 2007. A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene. EMBO J. 26:5061-5070. http://dx.doi.org/10.1038/sj.emboj.7601913
-
(2007)
EMBO J.
, vol.26
, pp. 5061-5070
-
-
Uanschou, C.1
Siwiec, T.2
Pedrosa-Harand, A.3
Kerzendorfer, C.4
Sanchez-Moran, E.5
Novatchkova, M.6
Akimcheva, S.7
Woglar, A.8
Klein, F.9
Schlögelhofer, P.10
-
46
-
-
23944510641
-
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex
-
Varma, A.K., R.S. Brown, G. Birrane, and J.A. Ladias. 2005. Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex. Biochemistry. 44:10941-10946. http://dx.doi.org/10.1021/bi0509651
-
(2005)
Biochemistry.
, vol.44
, pp. 10941-10946
-
-
Varma, A.K.1
Brown, R.S.2
Birrane, G.3
Ladias, J.A.4
-
47
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang, B., S. Matsuoka, B.A. Ballif, D. Zhang, A. Smogorzewska, S.P. Gygi, and S.J. Elledge. 2007. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science. 316:1194-1198. http://dx.doi.org/10.1126/science.1139476
-
(2007)
Science.
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
Elledge, S.J.7
-
48
-
-
0028278325
-
The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development
-
Warren, A.J., W.H. Colledge, M.B.L. Carlton, M.J. Evans, A.J.H. Smith, and T.H. Rabbitts. 1994. The oncogenic cysteine-rich LIM domain protein rbtn2 is essential for erythroid development. Cell. 78:45-57. http://dx.doi.org/10.1016/0092-8674(94)90571-1
-
(1994)
Cell.
, vol.78
, pp. 45-57
-
-
Warren, A.J.1
Colledge, W.H.2
Carlton, M.B.L.3
Evans, M.J.4
Smith, A.J.H.5
Rabbitts, T.H.6
-
49
-
-
2542490186
-
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
-
Williams, R.S., M.S. Lee, D.D. Hau, and J.N. Glover. 2004. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat. Struct. Mol. Biol. 11:519-525. http://dx.doi.org/10.1038/nsmb776
-
(2004)
Nat. Struct. Mol. Biol.
, vol.11
, pp. 519-525
-
-
Williams, R.S.1
Lee, M.S.2
Hau, D.D.3
Glover, J.N.4
-
50
-
-
7844246154
-
Characterization of a carboxy-terminal BRCA1 interacting protein
-
Wong, A.K., P.A. Ormonde, R. Pero, Y. Chen, L. Lian, G. Salada, S. Berry, Q. Lawrence, P. Dayananth, P. Ha, et al. 1998. Characterization of a carboxy-terminal BRCA1 interacting protein. Oncogene. 17:2279-2285. http://dx.doi.org/10.1038/sj.onc.1202150
-
(1998)
Oncogene.
, vol.17
, pp. 2279-2285
-
-
Wong, A.K.1
Ormonde, P.A.2
Pero, R.3
Chen, Y.4
Lian, L.5
Salada, G.6
Berry, S.7
Lawrence, Q.8
Dayananth, P.9
Ha, P.10
-
51
-
-
14144253224
-
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
-
Yang, H., Q. Li, J. Fan, W.K. Holloman, and N.P. Pavletich. 2005. The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction. Nature. 433:653-657. http://dx.doi.org/10.1038/nature03234
-
(2005)
Nature.
, vol.433
, pp. 653-657
-
-
Yang, H.1
Li, Q.2
Fan, J.3
Holloman, W.K.4
Pavletich, N.P.5
-
52
-
-
77954313601
-
DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints
-
You, Z., and J.M. Bailis. 2010. DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints. Trends Cell Biol. 20:402-409. http://dx.doi.org/10.1016/j.tcb.2010.04.002
-
(2010)
Trends Cell Biol.
, vol.20
, pp. 402-409
-
-
You, Z.1
Bailis, J.M.2
-
53
-
-
72149103012
-
CtIP links DNA doublestrand break sensing to resection
-
You, Z., L.Z. Shi, Q. Zhu, P. Wu, Y.W. Zhang, A. Basilio, N. Tonnu, I.M. Verma, M.W. Berns, and T. Hunter. 2009. CtIP links DNA doublestrand break sensing to resection. Mol. Cell. 36:954-969. http://dx.doi.org/10.1016/j.molcel.2009.12.002
-
(2009)
Mol. Cell.
, vol.36
, pp. 954-969
-
-
You, Z.1
Shi, L.Z.2
Zhu, Q.3
Wu, P.4
Zhang, Y.W.5
Basilio, A.6
Tonnu, N.7
Verma, I.M.8
Berns, M.W.9
Hunter, T.10
-
54
-
-
0034674706
-
Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor
-
Yu, X., and R. Baer. 2000. Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor. J. Biol. Chem. 275:18541-18549. http://dx.doi.org/10.1074/jbc.M909494199
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18541-18549
-
-
Yu, X.1
Baer, R.2
-
55
-
-
6344264992
-
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains
-
Yu, X., and J. Chen. 2004. DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol. Cell. Biol. 24:9478-9486. http://dx.doi.org/10.1128/MCB.24.21.9478-9486.2004
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 9478-9486
-
-
Yu, X.1
Chen, J.2
-
56
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu, X., L.C. Wu, A.M. Bowcock, A. Aronheim, and R. Baer. 1998. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J. Biol. Chem. 273:25388-25392. http://dx.doi.org/10.1074/jbc.273.39.25388
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
57
-
-
67349246802
-
CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle
-
Yun, M.H., and K. Hiom. 2009. CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle. Nature. 459:460-463. http://dx.doi.org/10.1038/nature07955
-
(2009)
Nature.
, vol.459
, pp. 460-463
-
-
Yun, M.H.1
Hiom, K.2
-
58
-
-
78650995499
-
An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway
-
Zhang, Y., and M. Jasin. 2011. An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway. Nat. Struct. Mol. Biol. 18:80-84. http://dx.doi.org/10.1038/nsmb.1940
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 80-84
-
-
Zhang, Y.1
Jasin, M.2
-
59
-
-
33847413700
-
A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination
-
Zhao, G.Y., E. Sonoda, L.J. Barber, H. Oka, Y. Murakawa, K. Yamada, T. Ikura, X. Wang, M. Kobayashi, K. Yamamoto, et al. 2007. A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination. Mol. Cell. 25:663-675. http://dx.doi.org/10.1016/j.molcel.2007.01.029
-
(2007)
Mol. Cell.
, vol.25
, pp. 663-675
-
-
Zhao, G.Y.1
Sonoda, E.2
Barber, L.J.3
Oka, H.4
Murakawa, Y.5
Yamada, K.6
Ikura, T.7
Wang, X.8
Kobayashi, M.9
Yamamoto, K.10
-
60
-
-
51549095956
-
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
-
Zhu, Z., W.H. Chung, E.Y. Shim, S.E. Lee, and G. Ira. 2008. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell. 134:981-994. http://dx.doi.org/10.1016/j.cell.2008.08.037
-
(2008)
Cell.
, vol.134
, pp. 981-994
-
-
Zhu, Z.1
Chung, W.H.2
Shim, E.Y.3
Lee, S.E.4
Ira, G.5
|