Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences

EMBO Journal

Volumn 20, Issue 17, 2001, Pages 4704-4716

  Tutt, Andrew ^a   Bertwistle, David ^a   Valentine, Janet ^a   Gabriel, Anastasia ^a   Swift, Sally ^a   Ross, Gillian ^a   Griffin, Carol ^b   Thacker, John ^b   Ashworth, Alan ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

BRCA2; DNA repair; Homologous recombination; Single strand annealing; Sister chromatid exchange

Indexed keywords

BRCA2 PROTEIN; DOUBLE STRANDED DNA;

ANIMAL CELL; ARTICLE; BREAST CANCER; CHROMOSOME; DNA CROSS LINKING; DNA REPAIR; DNA STRAND BREAKAGE; GENE CONVERSION; GENE MUTATION; NONHUMAN; NUCLEOTIDE REPEAT; OVARY CANCER; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SISTER CHROMATID EXCHANGE; TUMOR CELL;

ALLELES; ANIMALS; BRCA2 PROTEIN; BREAST NEOPLASMS; CELL LINE; CLONING, MOLECULAR; DNA DAMAGE; DNA REPAIR; DRUG RESISTANCE, NEOPLASM; EXONS; FEMALE; GENETIC MARKERS; HUMANS; MICE; MUTAGENESIS, SITE-DIRECTED; MUTATION; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; RESTRICTION MAPPING; SEQUENCE DELETION; STEM CELLS; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0035801472     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.17.4704     Document Type: Article

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