The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells

Nature Cell Biology

Volumn 12, Issue 5, 2010, Pages 492-499

  Stolz, Ailine ^a   Ertych, Norman ^a   Kienitz, Anne ^a   Vogel, Celia ^a,e   Schneider, Verena ^a   Fritz, Barbara ^a   Jacob, Ralf ^a   Dittmar, Gunnar ^b   Weichert, Wilko ^c,f   Petersen, Iver ^d   Bastians, Holger ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^e NETHERLANDS CANCER INSTITUTE   (Netherlands)

^f UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; CHECKPOINT KINASE 2; PROTEIN P53;

ARTICLE; CANCER INHIBITION; CELL GROWTH; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME SEGREGATION; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GENE LOSS; HUMAN; HUMAN CELL; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; SOMATIC CELL; SPINDLE CELL;

BRCA1 PROTEIN; CELL LINE; CHROMOSOMAL INSTABILITY; HUMANS; MITOSIS; MITOTIC SPINDLE APPARATUS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 77951971957     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb2051     Document Type: Article

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