메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages 34-64

Antagonism by bioactive polyphenols against inflammation: A systematic view

Author keywords

ACE; AMPK; Antioxidation; Cytokine; FOXO; HIF; Inflammation; JAK STAT; MTORC1; NF B; Phytochemical; PI3K AkT; Polyphenol; TNF

Indexed keywords

AMYLOID; ANTHOCYANIN; BLOOD CLOTTING FACTOR; C REACTIVE PROTEIN; CAPSAICIN; CATECHIN; CHEMOKINE; CURCUMIN; CYTOKINE; GALLIC ACID; GELATINASE A; GENISTEIN; GINGEROL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; LEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; PATTERN RECOGNITION RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; POLYPHENOL; PROTEIN KINASE B; QUERCETIN; RESVERATROL; SERINE PROTEINASE OMI; THROMBOCYTE ACTIVATING FACTOR; TOLL LIKE RECEPTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR; UNINDEXED DRUG; ACTIVATING TRANSCRIPTION FACTOR 6; ALPHA INTERFERON; CAFFEIC ACID DERIVATIVE; HYPOXIA INDUCIBLE FACTOR; I KAPPA B; IMMUNOGLOBULIN; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 8; JANUS KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; POLYPHENOL DERIVATIVE; PROTEIN IRE1; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXO; TUMOR NECROSIS FACTOR ALPHA;

EID: 84893486058     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/1871528112666131119211002     Document Type: Review
Times cited : (42)

References (236)
  • 1
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan, C.; Ding, A. Nonresolving inflammation. Cell, 2010, 140(6), 871-882.
    • (2010) Cell , vol.140 , Issue.6 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 2
    • 84882289346 scopus 로고    scopus 로고
    • Contribution of the inflammasomes to autoinflammatory diseases and recent mouse models as research tools
    • Heymann M. C.; Rösen-Wolff A. Contribution of the inflammasomes to autoinflammatory diseases and recent mouse models as research tools. Clin. Immunol., 2013, 147(3), 175-184.
    • (2013) Clin. Immunol , vol.147 , Issue.3 , pp. 175-184
    • Heymann, M.C.1    Rösen-Wolff, A.2
  • 3
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G. S. Inflammation and metabolic disorders. Nature, 2006, 444, 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 4
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • Wellen, K. E.; Hotamisligil G. S. Inflammation, stress, and diabetes. J. Clin. Invest., 2005, 115, 1111-1119.
    • (2005) J. Clin. Invest , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 5
    • 48149091097 scopus 로고    scopus 로고
    • Epidemic inflammation: Pondering obesity
    • Nathan, C. Epidemic inflammation: pondering obesity. Mol. Med., 2008, 14, 485-492.
    • (2008) Mol. Med , vol.14 , pp. 485-492
    • Nathan, C.1
  • 6
    • 84867940403 scopus 로고    scopus 로고
    • New insights into the role of macrophages in adipose tissue inflammation and fatty liver disease: Modulation by endogenous omega-3 fatty acid-derived lipid mediators
    • Clària, J.; González-Périz, A.; López-Vicario, C.; Rius, B.; Titos, E. New insights into the role of macrophages in adipose tissue inflammation and fatty liver disease: modulation by endogenous omega-3 fatty acid-derived lipid mediators. Front. Immunol., 2011, 2, 49.
    • (2011) Front. Immunol , vol.2 , pp. 49
    • Clària, J.1    González-Périz, A.2    López-Vicario, C.3    Rius, B.4    Titos, E.5
  • 7
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross, R. Atherosclerosis-an inflammatory disease. N. Engl. J. Med., 1999, 340, 115-126.
    • (1999) N. Engl. J. Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 8
    • 84865485915 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. Inflammation in atherosclerosis. Arterioscler. Thromb. Vasc. Biol., 2012, 32, 2045-2051.
    • (2012) Arterioscler. Thromb. Vasc. Biol , vol.32 , pp. 2045-2051
    • Libby, P.1
  • 9
    • 84872166189 scopus 로고    scopus 로고
    • Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure
    • Swirski, F. K.; Nahrendorf M. Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science, 2013, 339, 161-166.
    • (2013) Science , vol.339 , pp. 161-166
    • Swirski, F.K.1    Nahrendorf, M.2
  • 10
    • 84872130535 scopus 로고    scopus 로고
    • Anti-Inflammatory therapy in chronic disease: Challenges and opportunities
    • Tabas, I.; Glass, C. K. Anti-Inflammatory therapy in chronic disease: challenges and opportunities. Science, 2013, 339, 166-172.
    • (2013) Science , vol.339 , pp. 166-172
    • Tabas, I.1    Glass, C.K.2
  • 11
    • 84874720620 scopus 로고    scopus 로고
    • Reactive oxygen species, Nox and angiotensin II in angiogenesis: Implications for retinopathy
    • Wilkinson-Berka, J. L.; Rana, I.; Armani, R.; Agrotis, A. Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy. Clin. Sci. (Lond), 2013, 124, 597-615.
    • (2013) Clin. Sci. (Lond) , vol.124 , pp. 597-615
    • Wilkinson-Berka, J.L.1    Rana, I.2    Armani, R.3    Agrotis, A.4
  • 12
    • 0037373455 scopus 로고    scopus 로고
    • Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein
    • Marnett, L. J.; Riggins, J. N.; West, J. D. Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J. Clin. Invest., 2003, 111, 583-593.
    • (2003) J. Clin. Invest , vol.111 , pp. 583-593
    • Marnett, L.J.1    Riggins, J.N.2    West, J.D.3
  • 13
    • 37149012352 scopus 로고    scopus 로고
    • Fenton chemistry in biology and medicine
    • Prousek, J. Fenton chemistry in biology and medicine. Pure. Appl. Chem., 2007, 79, 2325-2338.
    • (2007) Pure. Appl. Chem , vol.79 , pp. 2325-2338
    • Prousek, J.1
  • 14
    • 84867756222 scopus 로고    scopus 로고
    • Mitochondria and organismal longevity
    • Hwang, A. B.; Jeong, D. E.; Lee, S. J. Mitochondria and organismal longevity. Curr. Genomics, 2012, 13, 519-532.
    • (2012) Curr. Genomics , vol.13 , pp. 519-532
    • Hwang, A.B.1    Jeong, D.E.2    Lee, S.J.3
  • 15
    • 77950355880 scopus 로고    scopus 로고
    • SnapShot: Reactive Oxygen Intermediates (ROI)
    • Nathan C.; Ding A. SnapShot: Reactive Oxygen Intermediates (ROI). Cell, 2010, 140, 951-952.
    • (2010) Cell , vol.140 , pp. 951-952
    • Nathan, C.1    Ding, A.2
  • 16
    • 84867466090 scopus 로고    scopus 로고
    • Oxidatively induced DNA damage: Mechanisms, repair and disease
    • Dizdaroglu M. Oxidatively induced DNA damage: mechanisms, repair and disease. Cancer Lett., 2012, 327, 26-47.
    • (2012) Cancer Lett , vol.327 , pp. 26-47
    • Dizdaroglu, M.1
  • 17
    • 84655169936 scopus 로고    scopus 로고
    • Tumor suppressor genes and ROS: Complex networks of interactions
    • Vurusaner, B, Poli, G, Basaga, H. Tumor suppressor genes and ROS: complex networks of interactions. Free Radic. Biol. Med., 2012, 52, 7-18.
    • (2012) Free Radic. Biol. Med , vol.52 , pp. 7-18
    • Vurusaner, B.1    Poli, G.2    Basaga, H.3
  • 18
    • 77953485565 scopus 로고    scopus 로고
    • Molecular pathways linking inflammation and cancer
    • Mantovani, A. Molecular pathways linking inflammation and cancer. Curr. Mol. Med., 2010, 10, 369-373.
    • (2010) Curr. Mol. Med , vol.10 , pp. 369-373
    • Mantovani, A.1
  • 19
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov, S. I.; Greten, F. R.; Karin, M. Immunity, inflammation, and cancer. Cell, 2010, 140, 883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 20
    • 84872445265 scopus 로고    scopus 로고
    • Neutralizing tumorpromoting chronic inflammation: A magic bullet?
    • Coussens, L. M.; Zitvogel, L.; Palucka, A. K. Neutralizing tumorpromoting chronic inflammation: a magic bullet? Science, 2013, 339, 286-291.
    • (2013) Science , vol.339 , pp. 286-291
    • Coussens, L.M.1    Zitvogel, L.2    Palucka, A.K.3
  • 21
    • 84872166765 scopus 로고    scopus 로고
    • Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
    • Odegaard, J. I.; Chawla, A. Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis. Science, 2013, 339, 172-177.
    • (2013) Science , vol.339 , pp. 172-177
    • Odegaard, J.I.1    Chawla, A.2
  • 22
    • 84863041791 scopus 로고    scopus 로고
    • Role of pancreaticderived factor in type 2 diabetes: Evidence from pancreatic β cells and liver
    • Wang, C.; Burkhardt, B. R.; Guan, Y.; Yang, J. Role of pancreaticderived factor in type 2 diabetes: evidence from pancreatic β cells and liver. Nutr. Rev., 2012, 70(2), 100-106.
    • (2012) Nutr. Rev , vol.70 , Issue.2 , pp. 100-106
    • Wang, C.1    Burkhardt, B.R.2    Guan, Y.3    Yang, J.4
  • 23
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • Glass, C. K.; Saijo, K.; Winner, B.; Marchetto, M. C.; Gage F. H. Mechanisms underlying inflammation in neurodegeneration. Cell, 2010, 140, 918-934.
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 25
    • 84861960811 scopus 로고    scopus 로고
    • Hypoxia-inducible factors: Crosstalk between inflammation and metabolism
    • Shay, J. E.; Celeste Simon, M. Hypoxia-inducible factors: crosstalk between inflammation and metabolism. Semin. Cell Dev. Biol., 2012, 23(4), 389-394.
    • (2012) Semin. Cell Dev. Biol , vol.23 , Issue.4 , pp. 389-394
    • Shay, J.E.1    Celeste Simon, M.2
  • 26
    • 84866736117 scopus 로고    scopus 로고
    • Macrophage polarization and plasticity in health and disease
    • Biswas, S. K.; Chittezhath, M.; Shalova, I. N.; Lim, J. Y. Macrophage polarization and plasticity in health and disease. Immunol. Res., 2012, 53(1-3), 11-24.
    • (2012) Immunol. Res , vol.53 , Issue.1-3 , pp. 11-24
    • Biswas, S.K.1    Chittezhath, M.2    Shalova, I.N.3    Lim, J.Y.4
  • 27
    • 84885102672 scopus 로고    scopus 로고
    • Pathways mediating resolution of inflammation: When enough is too much
    • Fullerton, J. N.; O'Brien, A. J.; Gilroy, D. W. Pathways mediating resolution of inflammation: when enough is too much. J. Pathol., 2013, 231(1), 8-20.
    • (2013) J. Pathol , vol.231 , Issue.1 , pp. 8-20
    • Fullerton, J.N.1    O'Brien, A.J.2    Gilroy, D.W.3
  • 28
    • 84865435543 scopus 로고    scopus 로고
    • New lives given by cell death: Macrophage differentiation following their encounter with apoptotic leukocytes during the resolution of inflammation
    • Ariel, A.; Serhan, C. N. New lives given by cell death: macrophage differentiation following their encounter with apoptotic leukocytes during the resolution of inflammation. Front. Immunol., 2012, 3, 4.
    • (2012) Front. Immunol , vol.3 , pp. 4
    • Ariel, A.1    Serhan, C.N.2
  • 30
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi, O.; Akira, S. Pattern recognition receptors and inflammation. Cell, 2010, 140(6), 805-820.
    • (2010) Cell , vol.140 , Issue.6 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 31
    • 84865299726 scopus 로고    scopus 로고
    • PAMPs and DAMPs: Signal 0s that spur autophagy and immunity
    • Tang, D.; Kang, R.; Coyne, C. B.; Zeh, H. J.; Lotze, M. T. PAMPs and DAMPs: signal 0s that spur autophagy and immunity. Immunol. Rev., 2012, 249(1), 158-175.
    • (2012) Immunol. Rev , vol.249 , Issue.1 , pp. 158-175
    • Tang, D.1    Kang, R.2    Coyne, C.B.3    Zeh, H.J.4    Lotze, M.T.5
  • 32
    • 84877585473 scopus 로고    scopus 로고
    • Toll-like receptor activation and mechanical force stimulation promote the secretion of matrix metalloproteinases 1, 3 and 10 of human periodontal fibroblasts via p38, JNK and NF-kB
    • Lisboa, R. A.; Andrade, M. V.; Cunha-Melo, J. R.; Toll-like receptor activation and mechanical force stimulation promote the secretion of matrix metalloproteinases 1, 3 and 10 of human periodontal fibroblasts via p38, JNK and NF-kB. Arch. Oral Biol., 2013, 58(6), 731-739.
    • (2013) Arch. Oral Biol , vol.58 , Issue.6 , pp. 731-739
    • Lisboa, R.A.1    Andrade, M.V.2    Cunha-Melo, J.R.3
  • 33
    • 84885930898 scopus 로고    scopus 로고
    • Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264. 7 cells
    • Endale, M.; Park, S. C.; Kim, S.; Kim, S. H.; Yang, Y.; Cho, J. Y.; Rhee, M. H. Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264. 7 cells. Immunobiology, 2013, 218 (12), 1452-1467.
    • (2013) Immunobiology , vol.218 , Issue.12 , pp. 1452-1467
    • Endale, M.1    Park, S.C.2    Kim, S.3    Kim, S.H.4    Yang, Y.5    Cho, J.Y.6    Rhee, M.H.7
  • 34
    • 0036565888 scopus 로고    scopus 로고
    • Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: A molecular basis for priming and synergism with bacterial lipopolysaccharide
    • Bosisio, D.; Polentarutti, N.; Sironi, M.; Bernasconi, S.; Miyake, K.; Webb, G. R.; Martin, M. U.; Mantovani, A.; Muzio, M. Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood, 2002, 99(9), 3427-3431.
    • (2002) Blood , vol.99 , Issue.9 , pp. 3427-3431
    • Bosisio, D.1    Polentarutti, N.2    Sironi, M.3    Bernasconi, S.4    Miyake, K.5    Webb, G.R.6    Martin, M.U.7    Mantovani, A.8    Muzio, M.9
  • 35
    • 84884169017 scopus 로고    scopus 로고
    • Inflammation in tuberculosis: Interactions, imbalances and interventions
    • Kaufmann, S. H.; Dorhoi A. Inflammation in tuberculosis: interactions, imbalances and interventions. Curr. Opin. Immunol., 2013, 25(4), 441-449.
    • (2013) Curr. Opin. Immunol , vol.25 , Issue.4 , pp. 441-449
    • Kaufmann, S.H.1    Dorhoi, A.2
  • 36
    • 84866628737 scopus 로고    scopus 로고
    • The role of NF-κB activation during protection against Leishmania infection
    • Reinhard, K.; Huber, M.; Lohoff, M.; Visekruna, A. The role of NF-κB activation during protection against Leishmania infection. Int. J. Med. Microbiol., 2012, 302(4-5), 230-235.
    • (2012) Int. J. Med. Microbiol , vol.302 , Issue.4-5 , pp. 230-235
    • Reinhard, K.1    Huber, M.2    Lohoff, M.3    Visekruna, A.4
  • 38
    • 84867411780 scopus 로고    scopus 로고
    • Subversion of cytokine networks by virally encoded decoy receptors
    • Epperson, M. L.; Lee, C. A.; Fremont, D. H. Subversion of cytokine networks by virally encoded decoy receptors. Immunol. Rev., 2012, 250(1), 199-215.
    • (2012) Immunol. Rev , vol.250 , Issue.1 , pp. 199-215
    • Epperson, M.L.1    Lee, C.A.2    Fremont, D.H.3
  • 39
    • 34347336666 scopus 로고    scopus 로고
    • The role of chemokines as inflammatory mediators in chronic hepatitis C virus infection
    • Zeremski, M.; Petrovic, L. M.; Talal, A. H. The role of chemokines as inflammatory mediators in chronic hepatitis C virus infection. J. Viral Hepat., 2007, 14(10), 675-687.
    • (2007) J. Viral Hepat , vol.14 , Issue.10 , pp. 675-687
    • Zeremski, M.1    Petrovic, L.M.2    Talal, A.H.3
  • 40
  • 41
    • 84872294911 scopus 로고    scopus 로고
    • Immunovirological parameters and cytokines in HIV infection
    • Tasca, K. I.; Calvi, S. A.; Souza, Ldo, R. Immunovirological parameters and cytokines in HIV infection. Rev. Soc. Bras. Med. Trop., 2012, 45(6), 663-669.
    • (2012) Rev. Soc. Bras. Med. Trop , vol.45 , Issue.6 , pp. 663-669
    • Tasca, K.I.1    Calvi, S.A.2    Souza, L.R.3
  • 42
    • 80052139666 scopus 로고    scopus 로고
    • Sensing damage by the NLRP3 inflammasome
    • Leemans, J. C.; Cassel, S. L.; Sutterwala, F. S. Sensing damage by the NLRP3 inflammasome. Immunol. Rev., 2011, 243(1), 152-162.
    • (2011) Immunol. Rev , vol.243 , Issue.1 , pp. 152-162
    • Leemans, J.C.1    Cassel, S.L.2    Sutterwala, F.S.3
  • 43
    • 84866907391 scopus 로고    scopus 로고
    • The Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory Diseases
    • Yang, C. S.; Shin, D. M.; Jo, E. K. The Role of NLR-related Protein 3 Inflammasome in Host Defense and Inflammatory Diseases. Int. Neurourol. J., 2012, 16(1), 2-12.
    • (2012) Int. Neurourol. J , vol.16 , Issue.1 , pp. 2-12
    • Yang, C.S.1    Shin, D.M.2    Jo, E.K.3
  • 44
    • 57149122316 scopus 로고    scopus 로고
    • Complexity of complement activation in sepsis
    • Markiewski, M. M.; DeAngelis, R. A.; Lambris, J. D. Complexity of complement activation in sepsis. J. Cell Mol. Med., 2008, 12(6A), 2245-2254.
    • (2008) J. Cell Mol. Med , vol.12 , Issue.6 A , pp. 2245-2254
    • Markiewski, M.M.1    DeAngelis, R.A.2    Lambris, J.D.3
  • 45
    • 84859778293 scopus 로고    scopus 로고
    • MTOR signaling in growth control and disease
    • Laplante, M.; Sabatini, D. M. mTOR signaling in growth control and disease. Cell, 2012, 149, 274-293.
    • (2012) Cell , vol.149 , pp. 274-293
    • Laplante, M.1    Sabatini, D.M.2
  • 46
    • 34347220473 scopus 로고    scopus 로고
    • Defining the role of mTOR in cancer
    • Guertin, D. A.; Sabatini, D. M. Defining the role of mTOR in cancer. Cancer Cell, 2007, 12, 9-22.
    • (2007) Cancer Cell , vol.12 , pp. 9-22
    • Guertin, D.A.1    Sabatini, D.M.2
  • 47
    • 84858079914 scopus 로고    scopus 로고
    • PI3K/AKT/mTOR Pathway in angiogenesis
    • Karar, J.; Maity, A. PI3K/AKT/mTOR Pathway in angiogenesis. Front. Mol. Neurosci., 2010, 4, 51.
    • (2010) Front. Mol. Neurosci , vol.4 , pp. 51
    • Karar, J.1    Maity, A.2
  • 48
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil, G. S. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell, 2010, 140(6), 900-917.
    • (2010) Cell , vol.140 , Issue.6 , pp. 900-917
    • Hotamisligil, G.S.1
  • 50
    • 84872585484 scopus 로고    scopus 로고
    • Focus issue: Understanding mechanisms of inflammation
    • Foley, J. F. Focus issue: understanding mechanisms of inflammation. Sci. Signal., 2013, 6(258), eg2.
    • (2013) Sci. Signal , vol.6 , Issue.258
    • Foley, J.F.1
  • 53
    • 84870383878 scopus 로고    scopus 로고
    • Tumor necrosis factor
    • Chu, W. M. Tumor necrosis factor. Cancer Lett., 2013, 328, 222-225.
    • (2013) Cancer Lett , vol.328 , pp. 222-225
    • Chu, W.M.1
  • 54
    • 79951829343 scopus 로고    scopus 로고
    • Hypoxia and inflammation
    • Eltzschig, H. K.; Carmeliet P. Hypoxia and inflammation. N. Engl. J. Med., 2011, 364(7), 656-665.
    • (2011) N. Engl. J. Med , vol.364 , Issue.7 , pp. 656-665
    • Eltzschig, H.K.1    Carmeliet, P.2
  • 55
    • 78149409458 scopus 로고    scopus 로고
    • Hypoxia-inducible factors as essential regulators of inflammation
    • Imtiyaz, H. Z.; Simon, M. C. Hypoxia-inducible factors as essential regulators of inflammation. Curr. Top. Microbiol. Immunol., 2010, 345, 105-120.
    • (2010) Curr. Top. Microbiol. Immunol , vol.345 , pp. 105-120
    • Imtiyaz, H.Z.1    Simon, M.C.2
  • 56
    • 84885950065 scopus 로고    scopus 로고
    • Targeting the HIF pathway in inflammation and immunity
    • Scholz, C. C.; Taylor, C. T. Targeting the HIF pathway in inflammation and immunity. Curr. Opin. Pharmacol., 2013, 13(14), 646-653.
    • (2013) Curr. Opin. Pharmacol , vol.13 , Issue.14 , pp. 646-653
    • Scholz, C.C.1    Taylor, C.T.2
  • 57
    • 84869119767 scopus 로고    scopus 로고
    • Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes
    • Jiang, S.; Wang, W.; Miner, J.; Fromm, M. Cross regulation of sirtuin 1, AMPK, and PPARγ in conjugated linoleic acid treated adipocytes. PLoS One, 2012, 7(11), e48874.
    • (2012) PLoS One , vol.7 , Issue.11
    • Jiang, S.1    Wang, W.2    Miner, J.3    Fromm, M.4
  • 58
    • 70450204007 scopus 로고    scopus 로고
    • An emerging role of mTOR in lipid biosynthesis
    • Laplante, M.; Sabatini, D. M. An emerging role of mTOR in lipid biosynthesis. Curr. Biol., 2009, 19, R1046-R1052.
    • (2009) Curr. Biol , vol.19
    • Laplante, M.1    Sabatini, D.M.2
  • 59
    • 38149120449 scopus 로고    scopus 로고
    • Targeting phosphoinositide 3-kinase: Moving towards therapy
    • Marone, R.; Cmiljanovic, V.; Giese, B.; Wymann, M. P. Targeting phosphoinositide 3-kinase: moving towards therapy. Biochim. Biophys. Acta, 2008, 1784(1), 159-185.
    • (2008) Biochim. Biophys. Acta , vol.1784 , Issue.1 , pp. 159-185
    • Marone, R.1    Cmiljanovic, V.2    Giese, B.3    Wymann, M.P.4
  • 60
    • 33751268902 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis
    • Reedquist, K. A.; Ludikhuize, J.; Tak, P. P. Phosphoinositide 3-kinase signalling and FoxO transcription factors in rheumatoid arthritis. Biochem. Soc. Trans., 2006, 34(Pt 5), 727-730.
    • (2006) Biochem. Soc. Trans , vol.34 , Issue.PART 5 , pp. 727-730
    • Reedquist, K.A.1    Ludikhuize, J.2    Tak, P.P.3
  • 61
    • 0034988813 scopus 로고    scopus 로고
    • Adenovirus type 7 induces interleukin-8 production via activation of extracellular regulated kinase 1/2
    • Alcorn, M. J.; Booth, J. L.; Coggeshall, K. M.; Metcalf, J. P. Adenovirus type 7 induces interleukin-8 production via activation of extracellular regulated kinase 1/2. J. Virol., 2001, 75(14), 6450-6459.
    • (2001) J. Virol , vol.75 , Issue.14 , pp. 6450-6459
    • Alcorn, M.J.1    Booth, J.L.2    Coggeshall, K.M.3    Metcalf, J.P.4
  • 62
    • 84859972127 scopus 로고    scopus 로고
    • JAK and STAT signaling molecules in immunoregulation and immune-mediated disease
    • O'Shea, J. J.; Plenge, R. JAK and STAT signaling molecules in immunoregulation and immune-mediated disease. Immunity, 2012, 36(4), 542-550.
    • (2012) Immunity , vol.36 , Issue.4 , pp. 542-550
    • O'Shea, J.J.1    Plenge, R.2
  • 63
    • 68949131070 scopus 로고    scopus 로고
    • STAT3 in CD4+ T helper cell differentiation and inflammatory diseases
    • Egwuagu, C. E. STAT3 in CD4+ T helper cell differentiation and inflammatory diseases. Cytokine, 2009, 47(3), 149-156.
    • (2009) Cytokine , vol.47 , Issue.3 , pp. 149-156
    • Egwuagu, C.E.1
  • 64
    • 84863792755 scopus 로고    scopus 로고
    • Fractalkine upregulates inflammation through CX3CR1 and the Jak-Stat pathway in severe acute pancreatitis rat model
    • Huang, L. Y.; Chen, P.; Xu, L. X.; Zhou, Y. F.; Zhang, Y. P.; Yuan, Y. Z. Fractalkine upregulates inflammation through CX3CR1 and the Jak-Stat pathway in severe acute pancreatitis rat model. Inflammation, 2012, 35(3), 1023-1030.
    • (2012) Inflammation , vol.35 , Issue.3 , pp. 1023-1030
    • Huang, L.Y.1    Chen, P.2    Xu, L.X.3    Zhou, Y.F.4    Zhang, Y.P.5    Yuan, Y.Z.6
  • 66
    • 84871048026 scopus 로고    scopus 로고
    • Purinergic signaling during inflammation
    • Eltzschig, H. K.; Sitkovsky, M. V.; Robson, S. C. Purinergic signaling during inflammation. N. Engl. J. Med., 2012, 367(24), 2322-2333.
    • (2012) N. Engl. J. Med , vol.367 , Issue.24 , pp. 2322-2333
    • Eltzschig, H.K.1    Sitkovsky, M.V.2    Robson, S.C.3
  • 67
    • 77949358343 scopus 로고    scopus 로고
    • Blood coagulation as an intrinsic pathway for proinflammation: A mini review
    • Chu, A. J. Blood coagulation as an intrinsic pathway for proinflammation: a mini review. Inflamm. Allergy Drug Targets, 2010, 9, 32-44.
    • (2010) Inflamm. Allergy Drug Targets , vol.9 , pp. 32-44
    • Chu, A.J.1
  • 68
    • 32844470037 scopus 로고    scopus 로고
    • Role of tissue factor in thrombosis: Coagulationinflammation-thrombosis circuit
    • Chu, A. J. Role of tissue factor in thrombosis: coagulationinflammation-thrombosis circuit. Front. Biosci., 2006, 11, 256-271.
    • (2006) Front. Biosci , vol.11 , pp. 256-271
    • Chu, A.J.1
  • 69
    • 34547485957 scopus 로고    scopus 로고
    • Multifunctional effects of bradykinin on glial cells in relation to potential antiinflammatory effects
    • Noda, M.; Sasaki, K.; Ifuku, M.; Wada, K. Multifunctional effects of bradykinin on glial cells in relation to potential antiinflammatory effects. Neurochem. Int., 2007, 51(2-4), 185-191.
    • (2007) Neurochem. Int , vol.51 , Issue.2-4 , pp. 185-191
    • Noda, M.1    Sasaki, K.2    Ifuku, M.3    Wada, K.4
  • 71
    • 84881118554 scopus 로고    scopus 로고
    • Cellular signalling of the receptor for advanced glycation end products (RAGE)
    • Xie, J.; Méndez, J. D.; Méndez-Valenzuela, V.; Aguilar-Hernández, M. M. Cellular signalling of the receptor for advanced glycation end products (RAGE). Cell Signal., 2013, 25(11), 2185-2197.
    • (2013) Cell Signal , vol.25 , Issue.11 , pp. 2185-2197
    • Xie, J.1    Méndez, J.D.2    Méndez-Valenzuela, V.3    Aguilar-Hernández, M.M.4
  • 72
    • 0033081409 scopus 로고    scopus 로고
    • The physiological structure of human C-reactive protein and its complex with phosphocholine
    • Thompson, D.; Pepys, M. B.; Wood, S. P. The physiological structure of human C-reactive protein and its complex with phosphocholine. Structure, 1999, 7 (2), 169-77.
    • (1999) Structure , vol.7 , Issue.2 , pp. 169-177
    • Thompson, D.1    Pepys, M.B.2    Wood, S.P.3
  • 73
    • 84865511829 scopus 로고    scopus 로고
    • Plasmin as a proinflammatory cell activator
    • Syrovets, T.; Lunov, O.; Simmet, T. Plasmin as a proinflammatory cell activator. J. Leukoc. Biol., 2012, 92(3), 509-519.
    • (2012) J. Leukoc. Biol , vol.92 , Issue.3 , pp. 509-519
    • Syrovets, T.1    Lunov, O.2    Simmet, T.3
  • 74
    • 84869023220 scopus 로고    scopus 로고
    • The serine protease plasmin triggers expression of the CC-chemokine ligand 20 in dendritic cells via Akt/NF-κB-dependent pathways
    • Li, X.; Syrovets, T.; Simmet, T. The serine protease plasmin triggers expression of the CC-chemokine ligand 20 in dendritic cells via Akt/NF-κB-dependent pathways. J. Biomed. Biotechnol., 2012, 2012, 186710.
    • (2012) J. Biomed. Biotechnol , vol.2012 , pp. 186710
    • Li, X.1    Syrovets, T.2    Simmet, T.3
  • 75
    • 33745445478 scopus 로고    scopus 로고
    • TSG-6: A pluripotent inflammatory mediator?
    • Milner, C. M.; Higman, V. A.; Day, A. J. TSG-6: a pluripotent inflammatory mediator? Biochem. Soc. Trans., 2006, 34(Pt 3), 446-450.
    • (2006) Biochem. Soc. Trans , vol.34 , Issue.PART 3 , pp. 446-450
    • Milner, C.M.1    Higman, V.A.2    Day, A.J.3
  • 76
    • 84872041743 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS)-a family of fate deciding molecules pivotal in constructive inflammation and wound healing
    • Bryan, N.; Ahswin, H.; Smart, N.; Bayon, Y.; Wohlert, S.; Hunt, J. A. Reactive oxygen species (ROS)-a family of fate deciding molecules pivotal in constructive inflammation and wound healing. Eur. Cell Mater., 2012, 24, 249-261.
    • (2012) Eur. Cell Mater , vol.24 , pp. 249-261
    • Bryan, N.1    Ahswin, H.2    Smart, N.3    Bayon, Y.4    Wohlert, S.5    Hunt, J.A.6
  • 77
    • 79952712223 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species drive proinflammatory cytokine production
    • Naik, E.; Dixit, V. M. Mitochondrial reactive oxygen species drive proinflammatory cytokine production. J. Exp. Med., 2011, 208, 417-420.
    • (2011) J. Exp. Med , vol.208 , pp. 417-420
    • Naik, E.1    Dixit, V.M.2
  • 78
    • 0033053617 scopus 로고    scopus 로고
    • Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity
    • Bonizzi, G.; Piette, J.; Schoonbroodt, S.; Greimers, R.; Havard, L.; Merville, M. P.; Bours, V. Reactive oxygen intermediate-dependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity. Mol. Cell Biol., 1999, 19, 1950-1960.
    • (1999) Mol. Cell Biol , vol.19 , pp. 1950-1960
    • Bonizzi, G.1    Piette, J.2    Schoonbroodt, S.3    Greimers, R.4    Havard, L.5    Merville, M.P.6    Bours, V.7
  • 79
    • 8344273480 scopus 로고    scopus 로고
    • Nuclear factor kappa B activation by NADPH oxidases
    • Clark, R. A.; Valente, A. J. Nuclear factor kappa B activation by NADPH oxidases. Mech. Ageing Dev., 2004, 125, 799-810.
    • (2004) Mech. Ageing Dev , vol.125 , pp. 799-810
    • Clark, R.A.1    Valente, A.J.2
  • 80
    • 10644262971 scopus 로고    scopus 로고
    • The Nox family of NAD(P)H oxidases: Host defense and beyond
    • Geiszt, M.; Leto, T. L. The Nox family of NAD(P)H oxidases: host defense and beyond. J. Biol. Chem., 2004, 279, 51715-51718.
    • (2004) J. Biol. Chem , vol.279 , pp. 51715-51718
    • Geiszt, M.1    Leto, T.L.2
  • 83
    • 47749151450 scopus 로고    scopus 로고
    • Biological Roles for the NOX Family NADPH Oxidases
    • Nauseef, W. M. Biological Roles for the NOX Family NADPH Oxidases. J. Biol. Chem., 2008, 283, 16961-16965.
    • (2008) J. Biol. Chem , vol.283 , pp. 16961-16965
    • Nauseef, W.M.1
  • 84
    • 3042660859 scopus 로고    scopus 로고
    • Physiological roles of xanthine oxidoreductase
    • Harrison, R. Physiological roles of xanthine oxidoreductase. Drug Metab. Rev., 2004, 36, 363-375.
    • (2004) Drug Metab. Rev , vol.36 , pp. 363-375
    • Harrison, R.1
  • 85
    • 84864403641 scopus 로고    scopus 로고
    • Role of NADPH oxidase/ROS in proinflammatory mediators-induced airway and pulmonary diseases
    • Lee, I. T.; Yang, C. M. Role of NADPH oxidase/ROS in proinflammatory mediators-induced airway and pulmonary diseases. Biochem. Pharmacol., 2012, 84(5), 581-590.
    • (2012) Biochem. Pharmacol , vol.84 , Issue.5 , pp. 581-590
    • Lee, I.T.1    Yang, C.M.2
  • 86
    • 3442884545 scopus 로고    scopus 로고
    • The effects of calpain inhibition on IkB alpha degradation after activation of PBMCs: Identification of the calpain cleavage sites
    • Schaecher, K.; Goust, J. M.; Banik, N. L. The effects of calpain inhibition on IkB alpha degradation after activation of PBMCs: identification of the calpain cleavage sites. Neurochem. Res., 2004, 29(7), 1443-1451.
    • (2004) Neurochem. Res , vol.29 , Issue.7 , pp. 1443-1451
    • Schaecher, K.1    Goust, J.M.2    Banik, N.L.3
  • 88
    • 84858783225 scopus 로고    scopus 로고
    • CD40 ligand: A neoinflammatory molecule in vascular diseases
    • Hassan, G. S.; Merhi, Y.; Mourad, W. CD40 ligand: a neoinflammatory molecule in vascular diseases. Immunobiology, 2012, 217(5), 521-532.
    • (2012) Immunobiology , vol.217 , Issue.5 , pp. 521-532
    • Hassan, G.S.1    Merhi, Y.2    Mourad, W.3
  • 89
    • 56449099652 scopus 로고    scopus 로고
    • CD40-CD40 ligand interactions in oxidative stress, inflammation and vascular disease
    • Rizvi, M.; Pathak, D.; Freedman, J. E.; Chakrabarti S. CD40-CD40 ligand interactions in oxidative stress, inflammation and vascular disease. Trends Mol. Med., 2008, 14(12), 530-538.
    • (2008) Trends Mol. Med , vol.14 , Issue.12 , pp. 530-538
    • Rizvi, M.1    Pathak, D.2    Freedman, J.E.3    Chakrabarti, S.4
  • 90
    • 82955233553 scopus 로고    scopus 로고
    • The role of mast cells in allergic inflammation
    • Amin, K. The role of mast cells in allergic inflammation. Respir. Med., 2012, 106(1), 9-14.
    • (2012) Respir. Med , vol.106 , Issue.1 , pp. 9-14
    • Amin, K.1
  • 92
    • 84870562887 scopus 로고    scopus 로고
    • Role of high mobility group box 1 in inflammatory disease: Focus on sepsis
    • Bae, J. S. Role of high mobility group box 1 in inflammatory disease: focus on sepsis. Arch. Pharm. Res., 2012, 35(9), 1511-1523.
    • (2012) Arch. Pharm. Res , vol.35 , Issue.9 , pp. 1511-1523
    • Bae, J.S.1
  • 93
    • 79959956336 scopus 로고    scopus 로고
    • AMP-activated protein kinase inhibits NF-κB signaling and inflammation: Impact on healthspan and lifespan
    • Salminen, A.; Hyttinen, J. M.; Kaarniranta, K. AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan. J. Mol. Med. (Berl), 2011, 89(7), 667-676.
    • (2011) J. Mol. Med. (Berl) , vol.89 , Issue.7 , pp. 667-676
    • Salminen, A.1    Hyttinen, J.M.2    Kaarniranta, K.3
  • 94
    • 80052971895 scopus 로고    scopus 로고
    • PI3K-AKT-FoxO axis in cancer and aging
    • Tzivion, G.; Hay, N. PI3K-AKT-FoxO axis in cancer and aging. Biochim. Biophys. Acta, 2011, 1813(11), 1925-1931.
    • (2011) Biochim. Biophys. Acta , vol.1813 , Issue.11 , pp. 1925-1931
    • Tzivion, G.1    Hay, N.2
  • 95
    • 79960527353 scopus 로고    scopus 로고
    • FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease
    • Hwang, J. W.; Rajendrasozhan, S.; Yao, H.; Chung, S.; Sundar, I. K.; Huyck, H. L.; Pryhuber, G. S.; Kinnula, V. L; Rahman, I. FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease. J. Immunol., 2011, 187(2), 987-998.
    • (2011) J. Immunol , vol.187 , Issue.2 , pp. 987-998
    • Hwang, J.W.1    Rajendrasozhan, S.2    Yao, H.3    Chung, S.4    Sundar, I.K.5    Huyck, H.L.6    Pryhuber, G.S.7    Kinnula, V.L.8    Rahman, I.9
  • 96
    • 70349507649 scopus 로고    scopus 로고
    • FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation
    • Zhou, W.; Cao, Q.; Peng, Y.; Zhang, Q. J.; Castrillon, D. H.; DePinho, R. A.; Liu, Z. P. FoxO4 inhibits NF-kappaB and protects mice against colonic injury and inflammation. Gastroenterology, 2009, 137(4), 1403-1414.
    • (2009) Gastroenterology , vol.137 , Issue.4 , pp. 1403-1414
    • Zhou, W.1    Cao, Q.2    Peng, Y.3    Zhang, Q.J.4    Castrillon, D.H.5    DePinho, R.A.6    Liu, Z.P.7
  • 97
    • 77953811224 scopus 로고    scopus 로고
    • Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells
    • Ouyang, W.; Beckett, O.; Ma, Q.; Paik, J. H.; DePinho, R. A.; Li, M. O. Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells. Nat. Immunol., 2010, 11(7), 618-627.
    • (2010) Nat. Immunol , vol.11 , Issue.7 , pp. 618-627
    • Ouyang, W.1    Beckett, O.2    Ma, Q.3    Paik, J.H.4    DePinho, R.A.5    Li, M.O.6
  • 99
    • 84872576236 scopus 로고    scopus 로고
    • Metabolism of inflammation limited by AMPK and pseudo-starvation
    • O'Neill, L. A.; Hardie, D. G. Metabolism of inflammation limited by AMPK and pseudo-starvation. Nature, 2013, 493, 346-355.
    • (2013) Nature , vol.493 , pp. 346-355
    • O'Neill, L.A.1    Hardie, D.G.2
  • 100
    • 84879509534 scopus 로고    scopus 로고
    • Transcriptional repression of mitochondrial function in aging: A novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor
    • Liu, S.; Reilly, S. M.; Lee, C. H. Transcriptional repression of mitochondrial function in aging: a novel role for the silencing mediator of retinoid and thyroid hormone receptors co-repressor. Antioxid. Redox. Signal, 2013, 19(3), 299-309.
    • (2013) Antioxid. Redox. Signal , vol.19 , Issue.3 , pp. 299-309
    • Liu, S.1    Reilly, S.M.2    Lee, C.H.3
  • 101
    • 84872527628 scopus 로고    scopus 로고
    • mTOR is a key modulator of ageing and age-related disease
    • Johnson, S. C.; Rabinovitch, P. S.; Kaeberlein, M. mTOR is a key modulator of ageing and age-related disease. Nature, 2013, 493, 338-345.
    • (2013) Nature , vol.493 , pp. 338-345
    • Johnson, S.C.1    Rabinovitch, P.S.2    Kaeberlein, M.3
  • 103
    • 84867091296 scopus 로고    scopus 로고
    • Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies
    • Foster, J. G.; Blunt, M. D.; Carter, E.; Ward, S. G. Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies. Pharmacol. Rev., 2012, 64(4), 1027-1054.
    • (2012) Pharmacol. Rev , vol.64 , Issue.4 , pp. 1027-1054
    • Foster, J.G.1    Blunt, M.D.2    Carter, E.3    Ward, S.G.4
  • 104
    • 79958091431 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase isoforms as novel drug targets
    • Błajecka, K.; Borgström, A.; Arcaro A. Phosphatidylinositol 3-kinase isoforms as novel drug targets. Curr. Drug Targets, 2011, 12(7), 1056-1081.
    • (2011) Curr. Drug Targets , vol.12 , Issue.7 , pp. 1056-1081
    • Błajecka, K.1    Borgström, A.2    Arcaro, A.3
  • 105
    • 77649160181 scopus 로고    scopus 로고
    • PI3K inhibition in inflammation: Toward tailored therapies for specific diseases
    • Ghigo, A.; Damilano, F.; Braccini, L.; Hirsch, E. PI3K inhibition in inflammation: Toward tailored therapies for specific diseases. Bioessays, 2010, 32(3), 185-196.
    • (2010) Bioessays , vol.32 , Issue.3 , pp. 185-196
    • Ghigo, A.1    Damilano, F.2    Braccini, L.3    Hirsch, E.4
  • 106
    • 82355190327 scopus 로고    scopus 로고
    • Inhibition of TNF-α-induced inflammation by andrographolide via down-regulation of the PI3K/Akt signaling pathway
    • Chen, H. W.; Lin, A. H.; Chu, H. C.; Li, C. C.; Tsai, C. W.; Chao, C. Y.; Wang, C. J.; Lii, C. K.; Liu, K. L. Inhibition of TNF-α-induced inflammation by andrographolide via down-regulation of the PI3K/Akt signaling pathway. J. Nat. Prod., 2011, 74(11), 2408-2413.
    • (2011) J. Nat. Prod , vol.74 , Issue.11 , pp. 2408-2413
    • Chen, H.W.1    Lin, A.H.2    Chu, H.C.3    Li, C.C.4    Tsai, C.W.5    Chao, C.Y.6    Wang, C.J.7    Lii, C.K.8    Liu, K.L.9
  • 107
    • 0037199972 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
    • Guha, M.; Mackman, N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J. Biol. Chem., 2002, 277, 32124-32132.
    • (2002) J. Biol. Chem , vol.277 , pp. 32124-32132
    • Guha, M.1    Mackman, N.2
  • 108
    • 23944486750 scopus 로고    scopus 로고
    • Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
    • Martin, M.; Rehani, K.; Jope, R. S.; Michalek, S. M. Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat. Immunol., 2005, 6, 777-784.
    • (2005) Nat. Immunol , vol.6 , pp. 777-784
    • Martin, M.1    Rehani, K.2    Jope, R.S.3    Michalek, S.M.4
  • 109
    • 4544341116 scopus 로고    scopus 로고
    • Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor
    • Takada, Y.; Fang, X.; Jamaluddin, M. S.; Boyd, D. D.; Aggarwal, B. B. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. J. Biol. Chem., 2004, 279, 39541-39554.
    • (2004) J. Biol. Chem , vol.279 , pp. 39541-39554
    • Takada, Y.1    Fang, X.2    Jamaluddin, M.S.3    Boyd, D.D.4    Aggarwal, B.B.5
  • 110
    • 78651075836 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: A point of convergence for the host inflammatory response
    • Wang, H.; Brown, J.; Martin, M. Glycogen synthase kinase 3: A point of convergence for the host inflammatory response. Cytokine, 2011, 53(2), 130-140.
    • (2011) Cytokine , vol.53 , Issue.2 , pp. 130-140
    • Wang, H.1    Brown, J.2    Martin, M.3
  • 111
    • 84872065897 scopus 로고    scopus 로고
    • JAKs and STATs in immunity, immunodeficiency, and cancer
    • O'Shea, J. J.; Holland, S. M.; Staudt, L. M. JAKs and STATs in immunity, immunodeficiency, and cancer. N. Engl. J. Med., 2013, 368(2), 161-170.
    • (2013) N. Engl. J. Med , vol.368 , Issue.2 , pp. 161-170
    • O'Shea, J.J.1    Holland, S.M.2    Staudt, L.M.3
  • 112
    • 0035347847 scopus 로고    scopus 로고
    • Expression of E-and Pselectin in tumor necrosis factor-induced dermatitis in dogs
    • Tremblay, C.; Paradis, M.; Doré, M. Expression of E-and Pselectin in tumor necrosis factor-induced dermatitis in dogs. Vet. Pathol., 2001, 38, 261-8.
    • (2001) Vet. Pathol , vol.38 , pp. 261-268
    • Tremblay, C.1    Paradis, M.2    Doré, M.3
  • 113
    • 0032926847 scopus 로고    scopus 로고
    • Functional roles of MCP-1 in Propionibacterium acnes-induced, T cell-mediated pulmonary granulomatosis in rabbits
    • Ichiyasu, H.; Suga, M.; Matsukawa, A.; Iyonaga, K.; Mizobe, T.; Takahashi, T.; Ando, M. Functional roles of MCP-1 in Propionibacterium acnes-induced, T cell-mediated pulmonary granulomatosis in rabbits. J. Leukoc. Biol., 1999, 65, 482-491.
    • (1999) J. Leukoc. Biol , vol.65 , pp. 482-491
    • Ichiyasu, H.1    Suga, M.2    Matsukawa, A.3    Iyonaga, K.4    Mizobe, T.5    Takahashi, T.6    Ando, M.7
  • 114
    • 0037243234 scopus 로고    scopus 로고
    • Anti-interleukin-6 therapy for Crohn's disease
    • Ito, H. Anti-interleukin-6 therapy for Crohn's disease. Curr. Pharm. Des., 2003, 9, 295-305.
    • (2003) Curr. Pharm. Des , vol.9 , pp. 295-305
    • Ito, H.1
  • 115
    • 0037161360 scopus 로고    scopus 로고
    • Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein
    • Verma, S.; Li, S. H.; Badiwala, M. V.; Weisel, R. D.; Fedak, P. W.; Li, R. K.; Dhillon, B. Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation, 2002, 105, 1890-1896.
    • (2002) Circulation , vol.105 , pp. 1890-1896
    • Verma, S.1    Li, S.H.2    Badiwala, M.V.3    Weisel, R.D.4    Fedak, P.W.5    Li, R.K.6    Dhillon, B.7
  • 116
    • 0028239555 scopus 로고
    • Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome: Results from a randomized, double-blind, placebocontrolled trial: Phase III rhIL-1ra Sepsis Syndrome Study Group
    • Fisher, C. J. Jr.; Dhainaut, J. F.; Opal, S. M.; Pribble, J. P.; Balk, R. A.; Slotman, G. J. Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome: results from a randomized, double-blind, placebocontrolled trial: Phase III rhIL-1ra Sepsis Syndrome Study Group. J. Am. Med. Assoc., 1994, 271, 1836-1843.
    • (1994) J. Am. Med. Assoc , vol.271 , pp. 1836-1843
    • Fisher Jr., C.J.1    Dhainaut, J.F.2    Opal, S.M.3    Pribble, J.P.4    Balk, R.A.5    Slotman, G.J.6
  • 117
    • 0029348036 scopus 로고
    • Blockade of tumor necrosis factor reduces lipopolysaccharide lethality, but not the lethality of cecal ligation and puncture
    • Remick, D.; Manohar, P.; Bolgos, G.; Rodriguez, J.; Moldower, L.; Wollenberg, G. Blockade of tumor necrosis factor reduces lipopolysaccharide lethality, but not the lethality of cecal ligation and puncture. Shock, 1995, 4, 89-95.
    • (1995) Shock , vol.4 , pp. 89-95
    • Remick, D.1    Manohar, P.2    Bolgos, G.3    Rodriguez, J.4    Moldower, L.5    Wollenberg, G.6
  • 118
    • 34247169134 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor F(ab)2 antibody fragments protect in murine polymicrobial sepsis: Concentration and early intervention are fundamental to the outcome
    • Marquez-Velasco, R.; Bojalil, R.; Buelna, A.; Flores-Guzman, F.; Estevez-Ramirez, J.; Laguna, J.; Hernandez, A. M. Anti-tumor necrosis factor F(ab)2 antibody fragments protect in murine polymicrobial sepsis: concentration and early intervention are fundamental to the outcome. Inflamm. Res., 2006, 55, 378-384.
    • (2006) Inflamm. Res , vol.55 , pp. 378-384
    • Marquez-Velasco, R.1    Bojalil, R.2    Buelna, A.3    Flores-Guzman, F.4    Estevez-Ramirez, J.5    Laguna, J.6    Hernandez, A.M.7
  • 119
    • 8544262221 scopus 로고    scopus 로고
    • Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
    • Panacek, E. A.; Marshall, J.; Albertson, T. E.; Johnson, D. H.; Johnson, S.; MacArthur, R. D. Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab)2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit. Care Med., 2004, 32, 21730-21782.
    • (2004) Crit. Care Med , vol.32 , pp. 21730-21782
    • Panacek, E.A.1    Marshall, J.2    Albertson, T.E.3    Johnson, D.H.4    Johnson, S.5    McArthur, R.D.6
  • 120
    • 0032495658 scopus 로고    scopus 로고
    • Double-blind randomized controlled trial of monoclonal antibody to human tumor necrosis factor in treatment of septic shock: NORASEPT II Study Group
    • Abraham, E.; Anzueto, A.; Gutierrez, G.; Tessler, S.; San Pedro, G.; Wunderink, R. Double-blind randomized controlled trial of monoclonal antibody to human tumor necrosis factor in treatment of septic shock: NORASEPT II Study Group. Lancet, 1998, 351, 929-933.
    • (1998) Lancet , vol.351 , pp. 929-933
    • Abraham, E.1    Anzueto, A.2    Gutierrez, G.3    Tessler, S.4    San Pedro, G.5    Wunderink, R.6
  • 121
    • 0035100346 scopus 로고    scopus 로고
    • Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: A randomized, double-blind, placebo-controlled, multicenter phase III trial with 1, 342 patients
    • Abraham, E.; Laterre, P. F.; Garbino, J.; Pingleton, S.; Butler, T.; Dugernier, T. Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1, 342 patients. Crit. Care Med., 2001, 29, 503-510.
    • (2001) Crit. Care Med , vol.29 , pp. 503-510
    • Abraham, E.1    Laterre, P.F.2    Garbino, J.3    Pingleton, S.4    Butler, T.5    Dugernier, T.6
  • 123
    • 0034086432 scopus 로고    scopus 로고
    • Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression
    • Krunkosky, T. M.; Fischer, B. M.; Martin, L. D.; Jones, N.; Akley, N. J.; Adler, K. B. Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro. Signaling pathways controlling surface and gene expression. Am. J. Respir. Cell Mol. Biol., 2000, 22, 685-692.
    • (2000) Am. J. Respir. Cell Mol. Biol , vol.22 , pp. 685-692
    • Krunkosky, T.M.1    Fischer, B.M.2    Martin, L.D.3    Jones, N.4    Akley, N.J.5    Adler, K.B.6
  • 124
    • 0242413703 scopus 로고    scopus 로고
    • Lipopolysaccharide activates nuclear factor-kappaB through toll-like receptors and related molecules in cultured biliary epithelial cells
    • Harada, K.; Ohira, S.; Isse, K.; Ozaki, S.; Zen, Y.; Sato, Y.; Nakanuma, Y. Lipopolysaccharide activates nuclear factor-kappaB through toll-like receptors and related molecules in cultured biliary epithelial cells. Lab. Invest., 2003, 83, 1657-1667.
    • (2003) Lab. Invest , vol.83 , pp. 1657-1667
    • Harada, K.1    Ohira, S.2    Isse, K.3    Ozaki, S.4    Zen, Y.5    Sato, Y.6    Nakanuma, Y.7
  • 125
    • 0041317268 scopus 로고    scopus 로고
    • Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4
    • Tamai, R.; Asai, Y.; Hashimoto, M.; Fukase, K.; Kusumoto, S.; Ishida, H. Cell activation by monosaccharide lipid A analogues utilizing Toll-like receptor 4. Immunology, 2003, 110, 66-72.
    • (2003) Immunology , vol.110 , pp. 66-72
    • Tamai, R.1    Asai, Y.2    Hashimoto, M.3    Fukase, K.4    Kusumoto, S.5    Ishida, H.6
  • 126
    • 85047690873 scopus 로고    scopus 로고
    • Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes
    • Meng, G.; Rutz, M.; Schiemann, M.; Metzger, J.; Grabiec, A.; Schwandner, R. Antagonistic antibody prevents toll-like receptor 2-driven lethal shock-like syndromes. J. Clin. Invest., 2004, 113, 1473-1481.
    • (2004) J. Clin. Invest , vol.113 , pp. 1473-1481
    • Meng, G.1    Rutz, M.2    Schiemann, M.3    Metzger, J.4    Grabiec, A.5    Schwandner, R.6
  • 127
    • 1642405415 scopus 로고    scopus 로고
    • Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4
    • Bozinovski, S.; Jones, J.; Beavitt, S. J.; Cook, A. D.; Hamilton, J. A.; Anderson, G. P. Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4. Am. J. Physiol. Lung Cell Mol. Physio., 2004, 286, L877-885.
    • (2004) Am. J. Physiol. Lung Cell Mol. Physio , vol.286 , pp. 877-885
    • Bozinovski, S.1    Jones, J.2    Beavitt, S.J.3    Cook, A.D.4    Hamilton, J.A.5    Anderson, G.P.6
  • 128
    • 0037217697 scopus 로고    scopus 로고
    • Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans
    • Verbon, A.; Meijers, J. C.; Spek, C. A.; Hack, C. E.; Pribble, J. P.; Turner, T. Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans. J. Infect Dis., 2003, 187, 55-61.
    • (2003) J. Infect Dis , vol.187 , pp. 55-61
    • Verbon, A.1    Meijers, J.C.2    Spek, C.A.3    Hack, C.E.4    Pribble, J.P.5    Turner, T.6
  • 129
    • 0028835918 scopus 로고
    • CD14 and tissue factor expression by bacterial lipopolysaccharide-stimulated bovine alveolar macrophages in vitro
    • Yang, Z.; Carter, C. D.; Miller, M. S.; Bochsler, P. N. CD14 and tissue factor expression by bacterial lipopolysaccharide-stimulated bovine alveolar macrophages in vitro. Infect. Immunity, 1995, 63, 51-56.
    • (1995) Infect. Immunity , vol.63 , pp. 51-56
    • Yang, Z.1    Carter, C.D.2    Miller, M.S.3    Bochsler, P.N.4
  • 130
    • 0036721025 scopus 로고    scopus 로고
    • Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin based human whole blood model of inflammation
    • Mollnes, T. E.; Brekke, O. L.; Fung, M.; Fure, H.; Christiansen, D.; Bergseth, G. Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin based human whole blood model of inflammation. Blood, 2002, 100, 1869-1877.
    • (2002) Blood , vol.100 , pp. 1869-1877
    • Mollnes, T.E.1    Brekke, O.L.2    Fung, M.3    Fure, H.4    Christiansen, D.5    Bergseth, G.6
  • 131
    • 0035680366 scopus 로고    scopus 로고
    • Signal transduction system for interleukin-6 synthesis stimulated by lipopolysaccharide in human osteoblasts
    • Kondo, A.; Koshihara, Y.; Togari, A. Signal transduction system for interleukin-6 synthesis stimulated by lipopolysaccharide in human osteoblasts. J. Interferon Cytokine Res., 2001, 21, 943-950.
    • (2001) J. Interferon Cytokine Res , vol.21 , pp. 943-950
    • Kondo, A.1    Koshihara, Y.2    Togari, A.3
  • 132
    • 0344132646 scopus 로고    scopus 로고
    • Bacterial cell envelopes (ghosts) but not S-layers activate human endothelial cells (HUVECs) through sCD14 and LBP mechanism
    • Furst-Ladani, S.; Redl, H.; Haslberger, A.; Lubitz, W.; Messner, P.; Sleytr, U. B. Bacterial cell envelopes (ghosts) but not S-layers activate human endothelial cells (HUVECs) through sCD14 and LBP mechanism. Vaccine, 1999, 18, 440-448.
    • (1999) Vaccine , vol.18 , pp. 440-448
    • Furst-Ladani, S.1    Redl, H.2    Haslberger, A.3    Lubitz, W.4    Messner, P.5    Sleytr, U.B.6
  • 133
    • 0141922968 scopus 로고    scopus 로고
    • Effect of IC14, an anti-CD14 antibody, on plasma and cell-associated chemokines during human endotoxemia
    • Olszyna, D. P.; Verbon, A.; Pribble, J. P.; Turner, T.; Axtelle, T.; van Deventer, S. J. Effect of IC14, an anti-CD14 antibody, on plasma and cell-associated chemokines during human endotoxemia. Eur. Cytokine Netw., 2003, 14, 158-162.
    • (2003) Eur. Cytokine Netw , vol.14 , pp. 158-162
    • Olszyna, D.P.1    Verbon, A.2    Pribble, J.P.3    Turner, T.4    Axtelle, T.5    van Deventer, S.J.6
  • 134
    • 0033051016 scopus 로고    scopus 로고
    • Lipopolysaccharide enhances the production of vascular endothelial growth factor by human pulp cells in culture
    • Matsushita, K.; Motani, R.; Sakuta, T.; Nagaoka, S.; Matsuyama, T.; Abeyama, K. Lipopolysaccharide enhances the production of vascular endothelial growth factor by human pulp cells in culture. Infect Immun., 1999, 67, 1633-1639.
    • (1999) Infect Immun , vol.67 , pp. 1633-1639
    • Matsushita, K.1    Motani, R.2    Sakuta, T.3    Nagaoka, S.4    Matsuyama, T.5    Abeyama, K.6
  • 135
    • 84874160105 scopus 로고    scopus 로고
    • Oral inflammatory diseases and systemic inflammation: Role of the macrophage
    • Hasturk, H.; Kantarci, A.; Van Dyke, T. E. Oral inflammatory diseases and systemic inflammation: role of the macrophage. Front. Immunol., 2012, 3, 118.
    • (2012) Front. Immunol , vol.3 , pp. 118
    • Hasturk, H.1    Kantarci, A.2    Van Dyke, T.E.3
  • 136
    • 78751672975 scopus 로고    scopus 로고
    • Autophagy in immunity and inflammation
    • Levine, B.; Mizushima, N.; Virgin, H. W. Autophagy in immunity and inflammation. Nature, 2011, 469(7330), 323-335.
    • (2011) Nature , vol.469 , Issue.7330 , pp. 323-335
    • Levine, B.1    Mizushima, N.2    Virgin, H.W.3
  • 137
    • 84885953361 scopus 로고    scopus 로고
    • Resolution phase lipid mediators of inflammation: Agonists of resolution
    • Serhan, C. N.; Chiang, N. Resolution phase lipid mediators of inflammation: agonists of resolution. Curr. Opin. Pharmacol., 2013, 13(4), 632-640.
    • (2013) Curr. Opin. Pharmacol , vol.13 , Issue.4 , pp. 632-640
    • Serhan, C.N.1    Chiang, N.2
  • 138
    • 77953408091 scopus 로고    scopus 로고
    • Lipoxin and aspirin-triggered lipoxins
    • Romano, M. Lipoxin and aspirin-triggered lipoxins. ScientificWorld J., 2010, 10, 1048-1064.
    • (2010) ScientificWorld J , vol.10 , pp. 1048-1064
    • Romano, M.1
  • 139
    • 77952897873 scopus 로고    scopus 로고
    • Therapeutic applicability of anti-inflammatory and proresolving polyunsaturated fatty acid-derived lipid mediators
    • Bannenberg, G. L. Therapeutic applicability of anti-inflammatory and proresolving polyunsaturated fatty acid-derived lipid mediators. ScientificWorld J., 2010, 10, 676-712.
    • (2010) ScientificWorld J , vol.10 , pp. 676-712
    • Bannenberg, G.L.1
  • 141
  • 142
    • 84870038215 scopus 로고    scopus 로고
    • The vagus nerve and the inflammatory reflex-linking immunity and metabolism
    • Pavlov, V. A.; Tracey, K. J. The vagus nerve and the inflammatory reflex-linking immunity and metabolism. Nat. Rev. Endocrinol., 2012, 8(12), 743-754.
    • (2012) Nat. Rev. Endocrinol , vol.8 , Issue.12 , pp. 743-754
    • Pavlov, V.A.1    Tracey, K.J.2
  • 143
    • 33646788790 scopus 로고    scopus 로고
    • Glutamine prevents activation of NF-pB and stress kinase pathways, attenuates inflammatory cytokine release, and prevents acute respiratory distress syndrome (ARDS) following sepsis
    • Singleton, K. D.; Beckey, V. E.; Wischmeyer, P. E. Glutamine prevents activation of NF-pB and stress kinase pathways, attenuates inflammatory cytokine release, and prevents acute respiratory distress syndrome (ARDS) following sepsis. Shock, 2005, 24, 583-589.
    • (2005) Shock , vol.24 , pp. 583-589
    • Singleton, K.D.1    Beckey, V.E.2    Wischmeyer, P.E.3
  • 144
    • 84861673228 scopus 로고    scopus 로고
    • Novel therapeutic approaches in limiting oxidative stress and inflammation
    • Spychalowicz, A.; Wilk, G.; Śliwa, T.; Ludew, D.; Guzik, T. J. Novel therapeutic approaches in limiting oxidative stress and inflammation. Curr. Pharm. Biotechnol., 2012, 13(13), 2456-2466.
    • (2012) Curr. Pharm. Biotechnol , vol.13 , Issue.13 , pp. 2456-2466
    • Spychalowicz, A.1    Wilk, G.2    Śliwa, T.3    Ludew, D.4    Guzik, T.J.5
  • 145
    • 26844433194 scopus 로고    scopus 로고
    • Anti-inflammatory action of glucocorticoids-new mechanisms for old drugs
    • Rhen, T.; Cidlowski, J. A. Anti-inflammatory action of glucocorticoids-new mechanisms for old drugs. N. Engl. J. Med., 2005, 353(16), 1711-1723.
    • (2005) N. Engl. J. Med , vol.353 , Issue.16 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 146
    • 77954761710 scopus 로고    scopus 로고
    • AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival
    • Woodard, J.; Platanias, L. C. AMP-activated kinase (AMPK)-generated signals in malignant melanoma cell growth and survival. Biochem. Biophys. Res. Commun., 2010, 398(1), 135-139.
    • (2010) Biochem. Biophys. Res. Commun , vol.398 , Issue.1 , pp. 135-139
    • Woodard, J.1    Platanias, L.C.2
  • 147
    • 79957899628 scopus 로고    scopus 로고
    • Mechanisms for the antiinflammatory effects of statins
    • Bu, D. X.; Griffin, G.; Lichtman, A. H. Mechanisms for the antiinflammatory effects of statins. Curr. Opin. Lipidol., 2011, 22(3), 165-170.
    • (2011) Curr. Opin. Lipidol , vol.22 , Issue.3 , pp. 165-170
    • Bu, D.X.1    Griffin, G.2    Lichtman, A.H.3
  • 148
    • 77949354684 scopus 로고    scopus 로고
    • Statins suppress interleukin-6-induced monocyte chemoattractant protein-1 by inhibiting Janus kinase/signal transducers and activators of transcription pathways in human vascular endothelial cells
    • Jougasaki, M.; Ichiki, T.; Takenoshita, Y.; Setoguchi, M. Statins suppress interleukin-6-induced monocyte chemoattractant protein-1 by inhibiting Janus kinase/signal transducers and activators of transcription pathways in human vascular endothelial cells. Br. J. Pharmacol., 2010, 159(6), 1294-1303.
    • (2010) Br. J. Pharmacol , vol.159 , Issue.6 , pp. 1294-1303
    • Jougasaki, M.1    Ichiki, T.2    Takenoshita, Y.3    Setoguchi, M.4
  • 149
    • 79957650480 scopus 로고    scopus 로고
    • Atorvastatin reduces lipopolysaccharide-induced expression of C-reactive protein in human lung epithelial cells
    • Xing, X. Q.; Duan, S.; Wu, X. W.; Gan, Y.; Zhao, S. P.; Chen, P.; Wu, S. J. Atorvastatin reduces lipopolysaccharide-induced expression of C-reactive protein in human lung epithelial cells. Mol. Med. Rep., 2011, 4(4), 753-757.
    • (2011) Mol. Med. Rep , vol.4 , Issue.4 , pp. 753-757
    • Xing, X.Q.1    Duan, S.2    Wu, X.W.3    Gan, Y.4    Zhao, S.P.5    Chen, P.6    Wu, S.J.7
  • 151
  • 152
    • 11344277830 scopus 로고    scopus 로고
    • Statins for atherosclerosis-as good as it gets?
    • Ehrenstein, M. R.; Jury, E. C.; Mauri, C. Statins for atherosclerosis-as good as it gets? N. Engl. J. Med., 2005, 352(1), 73-75.
    • (2005) N. Engl. J. Med , vol.352 , Issue.1 , pp. 73-75
    • Ehrenstein, M.R.1    Jury, E.C.2    Mauri, C.3
  • 153
    • 37548998982 scopus 로고    scopus 로고
    • Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling
    • Nakao, T.; Shiota, M.; Tatemoto, Y.; Izumi, Y.; Iwao, H. Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling. J. Pharmacol. Sci., 2007, 105(4), 334-341.
    • (2007) J. Pharmacol. Sci , vol.105 , Issue.4 , pp. 334-341
    • Nakao, T.1    Shiota, M.2    Tatemoto, Y.3    Izumi, Y.4    Iwao, H.5
  • 154
    • 84888206250 scopus 로고    scopus 로고
    • Statins enhance expression of growth factors and activate the PI3K/Aktmediated signaling pathway after experimental intracerebral hemorrhage
    • Yang, D.; Han, Y.; Zhang, J.; Chopp, M.; Seyfried, D. M. Statins enhance expression of growth factors and activate the PI3K/Aktmediated signaling pathway after experimental intracerebral hemorrhage. World J. Neurosci., 2012, 2(2), 74-80.
    • (2012) World J. Neurosci , vol.2 , Issue.2 , pp. 74-80
    • Yang, D.1    Han, Y.2    Zhang, J.3    Chopp, M.4    Seyfried, D.M.5
  • 157
    • 84862556342 scopus 로고    scopus 로고
    • Enzymatic mechanisms regulating protein S-nitrosylation: Implications in health and disease
    • Anand, P.; Stamler, J. S. Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease. J. Mol. Med. (Berl), 2013, 90(3), 233-244.
    • (2013) J. Mol. Med. (Berl) , vol.90 , Issue.3 , pp. 233-244
    • Anand, P.1    Stamler, J.S.2
  • 159
    • 84879973586 scopus 로고    scopus 로고
    • Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b
    • Curtale, G.; Mirolo, M.; Renzi, T. A.; Rossato, M.; Bazzoni, F.; Locati, M. Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b. Proc. Natl. Acad. Sci. U S A., 2013, 110(28), 11499-11504.
    • (2013) Proc. Natl. Acad. Sci. U S A , vol.110 , Issue.28 , pp. 11499-11504
    • Curtale, G.1    Mirolo, M.2    Renzi, T.A.3    Rossato, M.4    Bazzoni, F.5    Locati, M.6
  • 160
    • 36048937343 scopus 로고    scopus 로고
    • Complement-targeted therapeutics
    • Ricklin, D.; Lambris, J. D. Complement-targeted therapeutics. Nat. Biotechnol., 2007, 25, 1265-1275.
    • (2007) Nat. Biotechnol , vol.25 , pp. 1265-1275
    • Ricklin, D.1    Lambris, J.D.2
  • 161
    • 0035947583 scopus 로고    scopus 로고
    • Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase
    • Pritchard, K. Jr.; Ackerman, A. W.; Gross, E. R.; Stepp, D. W.; Shi, Y.; Fontana, J. T.; Baker, J. E.; Sessa, W. C. Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase. J. Biol. Chem., 2001, 276(21), 17621-17624.
    • (2001) J. Biol. Chem , vol.276 , Issue.21 , pp. 17621-17624
    • Pritchard Jr., K.1    Ackerman, A.W.2    Gross, E.R.3    Stepp, D.W.4    Shi, Y.5    Fontana, J.T.6    Baker, J.E.7    Sessa, W.C.8
  • 163
    • 0034718540 scopus 로고    scopus 로고
    • Modulation of Akt kinase activity by binding to Hsp90
    • Sato, S.; Fujita, N.; Tsuruo, T. Modulation of Akt kinase activity by binding to Hsp90. Proc. Natl. Acad. Sci. USA, 2000, 97(20), 10832-10837.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.20 , pp. 10832-10837
    • Sato, S.1    Fujita, N.2    Tsuruo, T.3
  • 164
    • 0141819958 scopus 로고    scopus 로고
    • The stress response: Implications for the clinical development of hsp90 inhibitors
    • Whitesell, L.; Bagatell, R.; Falsey, R. The stress response: implications for the clinical development of hsp90 inhibitors. Curr. Cancer Drug Targets, 2003, 3(5), 349-358.
    • (2003) Curr. Cancer Drug Targets , vol.3 , Issue.5 , pp. 349-358
    • Whitesell, L.1    Bagatell, R.2    Falsey, R.3
  • 165
    • 79551632511 scopus 로고    scopus 로고
    • Chapter II: Blood coagulation fuels inflammation implementing a blood coagulation-inflammation-thrombosis circuit
    • In:, Tondre, R., Lebegue, C., Eds.; Nova Science Publishers, Inc
    • Chu, A. J. Chapter II: Blood coagulation fuels inflammation implementing a blood coagulation-inflammation-thrombosis circuit. In: Handbook of Hematology Research. Tondre, R., Lebegue, C., Eds.; Nova Science Publishers, Inc.; 2010, pp. 33-86.
    • (2010) Handbook of Hematology Research , pp. 33-86
    • Chu, A.J.1
  • 166
    • 42649132029 scopus 로고    scopus 로고
    • Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp
    • Kamio, N.; Hashizume, H.; Nakao, S.; Matsushima, K.; Sugiya, H. Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp. Biochem. Pharmacol., 2008, 75, 1974-1980.
    • (2008) Biochem. Pharmacol , vol.75 , pp. 1974-1980
    • Kamio, N.1    Hashizume, H.2    Nakao, S.3    Matsushima, K.4    Sugiya, H.5
  • 167
    • 0041328272 scopus 로고    scopus 로고
    • The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells
    • Arisato, T.; Sarker, K. P.; Kawahara, K.; Nakata, M.; Hashiguchi, T.; Osame, M.; Kitajima, I.; Maruyama, I. The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells. Cell Mol. Life Sci., 2003, 60, 1716-1724.
    • (2003) Cell Mol. Life Sci , vol.60 , pp. 1716-1724
    • Arisato, T.1    Sarker, K.P.2    Kawahara, K.3    Nakata, M.4    Hashiguchi, T.5    Osame, M.6    Kitajima, I.7    Maruyama, I.8
  • 168
    • 0036533649 scopus 로고    scopus 로고
    • Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
    • Asokananthan, N.; Graham, P. T.; Fink, J.; Knight, D. A.; Bakker, A. J.; McWilliam, A. S. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J. Immunol., 2002, 168, 3577-3585.
    • (2002) J. Immunol , vol.168 , pp. 3577-3585
    • Asokananthan, N.1    Graham, P.T.2    Fink, J.3    Knight, D.A.4    Bakker, A.J.5    McWilliam, A.S.6
  • 171
    • 33845995107 scopus 로고    scopus 로고
    • Serratia marcescens serralysin induces inflammatory responses through proteaseactivated receptor 2
    • Kida, Y.; Inoue, H.; Shimizu, T.; Kuwano, K. Serratia marcescens serralysin induces inflammatory responses through proteaseactivated receptor 2. Infect. Immun., 2007, 75, 164-174.
    • (2007) Infect. Immun , vol.75 , pp. 164-174
    • Kida, Y.1    Inoue, H.2    Shimizu, T.3    Kuwano, K.4
  • 172
    • 0036721731 scopus 로고    scopus 로고
    • Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release
    • Temkin, V.; Kantor, B.; Weg, V.; Hartman, M. L.; Levi-Schaffer, F. Tryptase activates the mitogen-activated protein kinase/activator protein-1 pathway in human peripheral blood eosinophils, causing cytokine production and release. J. Immunol., 2002, 169, 2662-2669.
    • (2002) J. Immunol , vol.169 , pp. 2662-2669
    • Temkin, V.1    Kantor, B.2    Weg, V.3    Hartman, M.L.4    Levi-Schaffer, F.5
  • 175
    • 36049027020 scopus 로고    scopus 로고
    • Protease-activated receptor-4 inhibition protects from multiorgan failure in a murine model of systemic inflammation
    • Slofstra, S. H.; Bijlsma, M. F.; Groot, A. P.; Reitsma, P. H.; Lindhout, T.; ten Cate, H.; Spek, C. A. Protease-activated receptor-4 inhibition protects from multiorgan failure in a murine model of systemic inflammation. Blood, 2007, 110, 3176-3182.
    • (2007) Blood , vol.110 , pp. 3176-3182
    • Slofstra, S.H.1    Bijlsma, M.F.2    Groot, A.P.3    Reitsma, P.H.4    Lindhout, T.5    ten Cate, H.6    Spek, C.A.7
  • 176
    • 84876577003 scopus 로고    scopus 로고
    • Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors
    • Mandard, S.; Patsouris, D. Nuclear control of the inflammatory response in mammals by peroxisome proliferator-activated receptors. PPAR Res., 2013, 2013, 613864.
    • (2013) PPAR Res , vol.2013 , pp. 613864
    • Mandard, S.1    Patsouris, D.2
  • 177
    • 84885611134 scopus 로고    scopus 로고
    • The Sirtuin system: The Holy Grail of Resveratrol?
    • Mohar, D. S.; Malik, S. The Sirtuin system: The Holy Grail of Resveratrol? J. Clin. Exp. Cardiolog., 2012, 3(11), pii: 216.
    • (2012) J. Clin. Exp. Cardiolog , vol.3 , Issue.11 , pp. 216
    • Mohar, D.S.1    Malik, S.2
  • 178
    • 80755167213 scopus 로고    scopus 로고
    • Nutritional antioxidants and adaptive cell responses: An update
    • Speciale, A.; Chirafisi, J.; Saija, A.; Cimino, F. Nutritional antioxidants and adaptive cell responses: an update. Curr. Mol. Med., 2011, 11, 770-789.
    • (2011) Curr. Mol. Med , vol.11 , pp. 770-789
    • Speciale, A.1    Chirafisi, J.2    Saija, A.3    Cimino, F.4
  • 179
    • 84862318573 scopus 로고    scopus 로고
    • Resveratrol and health: The starting point
    • Biasutto, L.; Mattarei, A.; Zoratti, M. Resveratrol and health: the starting point. Chembiochem., 2012, 13, 1256-1259.
    • (2012) Chembiochem , vol.13 , pp. 1256-1259
    • Biasutto, L.1    Mattarei, A.2    Zoratti, M.3
  • 181
    • 84862283308 scopus 로고    scopus 로고
    • Capsaicinoids and capsinoids. A? A systematic review of the evidence
    • Whiting, S.; Derbyshire, E.; Tiwari, B. K. Capsaicinoids and capsinoids. A? A systematic review of the evidence. Appetite, 2012, 59, 341-348.
    • (2012) Appetite , vol.59 , pp. 341-348
    • Whiting, S.1    Derbyshire, E.2    Tiwari, B.K.3
  • 182
    • 84871717518 scopus 로고    scopus 로고
    • Phytochemicals and their impact on adipose tissue inflammation and diabetes
    • Leiherer, A.; Mündlein, A.; Drexel, H. Phytochemicals and their impact on adipose tissue inflammation and diabetes. Vascul. Pharmacol., 2013, 58, 3-20.
    • (2013) Vascul. Pharmacol , vol.58 , pp. 3-20
    • Leiherer, A.1    Mündlein, A.2    Drexel, H.3
  • 183
    • 33745632762 scopus 로고    scopus 로고
    • The anti-inflammatory effect of curcumin in an experimentalmodel of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-p
    • Siddiqui, A. M.; Cui, X.; Wu, R.; Dong W.; Zhou, M.; Hu, M.; Simms, H. H.; Wang, P. The anti-inflammatory effect of curcumin in an experimentalmodel of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-p. Crit. Care Med., 2006, 34, 1874-1882.
    • (2006) Crit. Care Med , vol.34 , pp. 1874-1882
    • Siddiqui, A.M.1    Cui, X.2    Wu, R.3    Dong, W.4    Zhou, M.5    Hu, M.6    Simms, H.H.7    Wang, P.8
  • 184
    • 84925287216 scopus 로고    scopus 로고
    • Curcumin and curcumin-like molecules: From spice to drugs
    • Marchiani, A.; Rozzo, C.; Fadda, A.; Delogu, G.; Ruzza, P. Curcumin and curcumin-like molecules: from spice to drugs. Curr. Med. Chem., 2013, 21(2), 204-222.
    • (2013) Curr. Med. Chem , vol.21 , Issue.2 , pp. 204-222
    • Marchiani, A.1    Rozzo, C.2    Fadda, A.3    Delogu, G.4    Ruzza, P.5
  • 185
    • 84875399748 scopus 로고    scopus 로고
    • A review of therapeutic effects of curcumin
    • Noorafshan, A.; Ashkani-Esfahani, S. A review of therapeutic effects of curcumin. Curr. Pharm. Des., 2013, 19, 2032-2046.
    • (2013) Curr. Pharm. Des , vol.19 , pp. 2032-2046
    • Noorafshan, A.1    Ashkani-Esfahani, S.2
  • 187
    • 84867735113 scopus 로고    scopus 로고
    • Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle
    • Tsuda, S.; Egawa, T.; Ma, X.; Oshima, R.; Kurogi, E.; Hayashi, T. Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle. J. Nutr. Biochem., 2012, 23, 1403-1409.
    • (2012) J. Nutr. Biochem , vol.23 , pp. 1403-1409
    • Tsuda, S.1    Egawa, T.2    Ma, X.3    Oshima, R.4    Kurogi, E.5    Hayashi, T.6
  • 188
    • 84877970486 scopus 로고    scopus 로고
    • In vivo and In vitro anti{dotless}neoplastic actions of caffeic ccid phenethyl ester (CAPE): Therapeutic perspectives
    • Akyol, S.; Ozturk, G.; Ginis, Z.; Armutcu, F.; Yigitoglu, M. R.; Akyol, O. In vivo and In vitro anti{dotless}neoplastic actions of caffeic ccid phenethyl ester (CAPE): therapeutic perspectives. Nutr. Cancer, 2013, 65, 515-526.
    • (2013) Nutr. Cancer , vol.65 , pp. 515-526
    • Akyol, S.1    Ozturk, G.2    Ginis, Z.3    Armutcu, F.4    Yigitoglu, M.R.5    Akyol, O.6
  • 189
    • 80052986267 scopus 로고    scopus 로고
    • The molecular basis for the pharmacological activity of anthocyans
    • Domitrovic, R. The molecular basis for the pharmacological activity of anthocyans. Curr. Med. Chem., 2011, 18, 4454-4469.
    • (2011) Curr. Med. Chem , vol.18 , pp. 4454-4469
    • Domitrovic, R.1
  • 190
    • 84872730845 scopus 로고    scopus 로고
    • Novel epigallocatechin gallate analogs as potential anticancer agents: A patent review (2009-present)
    • Landis-Piwowar, K.; Chen, D.; Foldes, R.; Chan, T. H.; Dou, Q. P. Novel epigallocatechin gallate analogs as potential anticancer agents: a patent review (2009-present). Expert. Opin. Ther. Pat., 2013, 23, 189-202.
    • (2013) Expert. Opin. Ther. Pat , vol.23 , pp. 189-202
    • Landis-Piwowar, K.1    Chen, D.2    Foldes, R.3    Chan, T.H.4    Dou, Q.P.5
  • 191
    • 80555123045 scopus 로고    scopus 로고
    • Green tea catechin, epigallocatechin-3-gallate (EGCG): Mechanisms, perspectives and clinical applications
    • Singh, B. N.; Shankar, S.; Srivastava, R. K. Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications. Biochem. Pharmacol., 2011, 82(12), 1807-1821.
    • (2011) Biochem. Pharmacol , vol.82 , Issue.12 , pp. 1807-1821
    • Singh, B.N.1    Shankar, S.2    Srivastava, R.K.3
  • 192
    • 84874284327 scopus 로고    scopus 로고
    • Antiinfective properties of epigallocatechin-3-gallate (EGCG), a component of green tea
    • Steinmann, J.; Buer, J.; Pietschmann, T.; Steinmann, E. Antiinfective properties of epigallocatechin-3-gallate (EGCG), a component of green tea. Br. J. Pharmacol., 2013, 168, 1059-1073.
    • (2013) Br. J. Pharmacol , vol.168 , pp. 1059-1073
    • Steinmann, J.1    Buer, J.2    Pietschmann, T.3    Steinmann, E.4
  • 194
    • 34147182364 scopus 로고    scopus 로고
    • Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages
    • Chow, S. E.; Hshu, Y. C.; Wang, J. S.; Chen, J. K. Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages. J. Appl. Physiol., 2007, 102, 1520-1527.
    • (2007) J. Appl. Physiol , vol.102 , pp. 1520-1527
    • Chow, S.E.1    Hshu, Y.C.2    Wang, J.S.3    Chen, J.K.4
  • 195
    • 84875625176 scopus 로고    scopus 로고
    • Apocynin: Chemical and biophysical properties of a NADPH oxidase inhibitor
    • Petrônio, M. S.; Zeraik, M. L.; Fonseca, L. M.; Ximenes, V. F. Apocynin: chemical and biophysical properties of a NADPH oxidase inhibitor. Molecules, 2013, 18, 2821-2839.
    • (2013) Molecules , vol.18 , pp. 2821-2839
    • Petrônio, M.S.1    Zeraik, M.L.2    Fonseca, L.M.3    Ximenes, V.F.4
  • 196
    • 45549107844 scopus 로고    scopus 로고
    • Synthesis of resveratrol analogues, and evaluation of their cytotoxic and xanthine oxidase inhibitory activities
    • Huang, X. F.; Li, H. Q.; Shi, L.; Xue, J. Y.; Ruan, B. F.; Zhu, H. L. Synthesis of resveratrol analogues, and evaluation of their cytotoxic and xanthine oxidase inhibitory activities. Chem. Biodivers., 2008, 5, 636-642.
    • (2008) Chem. Biodivers , vol.5 , pp. 636-642
    • Huang, X.F.1    Li, H.Q.2    Shi, L.3    Xue, J.Y.4    Ruan, B.F.5    Zhu, H.L.6
  • 197
    • 71749105325 scopus 로고    scopus 로고
    • Insights into the inhibition of xanthine oxidase by curcumin
    • Shen, L.; Ji, H. F. Insights into the inhibition of xanthine oxidase by curcumin. Bioorg. Med. Chem. Lett., 2009, 19, 5990-5993.
    • (2009) Bioorg. Med. Chem. Lett , vol.19 , pp. 5990-5993
    • Shen, L.1    Ji, H.F.2
  • 198
    • 0031427013 scopus 로고    scopus 로고
    • Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis)
    • Aucamp, J.; Gaspar, A.; Hara, Y.; Apostolides Z. Inhibition of xanthine oxidase by catechins from tea (Camellia sinensis). Anticancer Res., 1997, 17, 4381-4385.
    • (1997) Anticancer Res , vol.17 , pp. 4381-4385
    • Aucamp, J.1    Gaspar, A.2    Hara, Y.3    Apostolides, Z.4
  • 200
    • 84864287434 scopus 로고    scopus 로고
    • Xanthine oxidase inhibitors from Vietnamese Blumea balsamifera L
    • Nguyen, M. T.; Nguyen, N. T. Xanthine oxidase inhibitors from Vietnamese Blumea balsamifera L. Phytother. Res., 2012, 26, 1178-1181.
    • (2012) Phytother. Res , vol.26 , pp. 1178-1181
    • Nguyen, M.T.1    Nguyen, N.T.2
  • 201
    • 84874823622 scopus 로고    scopus 로고
    • Extracts, anthocyanins and procyanidins from Aronia melanocarpa as radical scavengers and enzyme inhibitors
    • Bräunlich, M.; Slimestad, R.; Wangensteen, H.; Brede, C.; Malterud, K. E.; Barsett, H. Extracts, anthocyanins and procyanidins from Aronia melanocarpa as radical scavengers and enzyme inhibitors. Nutrients, 2013, 5, 663-678.
    • (2013) Nutrients , vol.5 , pp. 663-678
    • Bräunlich, M.1    Slimestad, R.2    Wangensteen, H.3    Brede, C.4    Malterud, K.E.5    Barsett, H.6
  • 202
    • 84864348569 scopus 로고    scopus 로고
    • NRF2 and cancer: The good, the bad and the importance of context
    • Sporn, M. B.; Liby, K. T. NRF2 and cancer: the good, the bad and the importance of context. Nat. Rev. Cancer, 2012, 12, 564-571.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 564-571
    • Sporn, M.B.1    Liby, K.T.2
  • 203
    • 84893437861 scopus 로고    scopus 로고
    • Phytochemicals in disease preventions and interventions: A current view
    • In:, Martirosyan, D.M., Ed.; Food Science Publishers, Inc.; Chapter 11
    • Chu, A. J. Phytochemicals in disease preventions and interventions: a current view. In: Introduction to Functional Food Science: Textbook. Martirosyan, D. M., Ed.; Food Science Publishers, Inc.; 2013, Chapter 11: Vol. 1, pp. 155-194.
    • (2013) Introduction to Functional Food Science: Textbook , vol.1 , pp. 155-194
    • Chu, A.J.1
  • 205
    • 84874104757 scopus 로고    scopus 로고
    • Molecular mechanisms of curcumin action: Signal transduction
    • Shehzad, A.; Lee, Y. S. Molecular mechanisms of curcumin action: signal transduction. Biofactors, 2013, 39, 27-36.
    • (2013) Biofactors , vol.39 , pp. 27-36
    • Shehzad, A.1    Lee, Y.S.2
  • 207
    • 78449241484 scopus 로고    scopus 로고
    • Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR
    • Liu, M.; Wilk, S. A.; Wang, A.; Zhou, L.; Wang, R. H.; Ogawa, W.; Deng, C.; Dong, L. Q.; Liu, F. Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR. J. Biol. Chem., 2010, 285(47), 36387-36394.
    • (2010) J. Biol. Chem , vol.285 , Issue.47 , pp. 36387-36394
    • Liu, M.1    Wilk, S.A.2    Wang, A.3    Zhou, L.4    Wang, R.H.5    Ogawa, W.6    Deng, C.7    Dong, L.Q.8    Liu, F.9
  • 208
    • 68549083507 scopus 로고    scopus 로고
    • Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling
    • Johnson, S. M.; Gulhati, P.; Arrieta, I.; Wang, X.; Uchida, T.; Gao, T.; Evers, B. M. Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling. Anticancer Res., 2009, 29(8), 3185-3190.
    • (2009) Anticancer Res , vol.29 , Issue.8 , pp. 3185-3190
    • Johnson, S.M.1    Gulhati, P.2    Arrieta, I.3    Wang, X.4    Uchida, T.5    Gao, T.6    Evers, B.M.7
  • 209
    • 59149091041 scopus 로고    scopus 로고
    • Curcumin disrupts the mammalian target of rapamycin-raptor complex
    • Beevers, C. S.; Chen, L.; Liu, L.; Luo, Y.; Webster, N. J.; Huang, S. Curcumin disrupts the mammalian target of rapamycin-raptor complex. Cancer Res., 2009, 69(3), 1000-1008.
    • (2009) Cancer Res , vol.69 , Issue.3 , pp. 1000-1008
    • Beevers, C.S.1    Chen, L.2    Liu, L.3    Luo, Y.4    Webster, N.J.5    Huang, S.6
  • 210
    • 56349161083 scopus 로고    scopus 로고
    • Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells
    • Madan, E.; Prasad, S.; Roy, P.; George, J.; Shukla, Y. Regulation of apoptosis by resveratrol through JAK/STAT and mitochondria mediated pathway in human epidermoid carcinoma A431 cells. Biochem. Biophys. Res. Commun., 2008, 377(4), 1232-1237.
    • (2008) Biochem. Biophys. Res. Commun , vol.377 , Issue.4 , pp. 1232-1237
    • Madan, E.1    Prasad, S.2    Roy, P.3    George, J.4    Shukla, Y.5
  • 211
    • 80053091840 scopus 로고    scopus 로고
    • Resveratrol down-regulates interferon-γ-inducible inflammatory genes in macrophages: Molecular mechanism via decreased STAT-1 activation
    • Chung, E. Y.; Kim, B. H.; Hong, J. T.; Lee, C. K.; Ahn, B. Nam, S.; Han, S. B.; Kim, Y. Resveratrol down-regulates interferon-γ-inducible inflammatory genes in macrophages: molecular mechanism via decreased STAT-1 activation. J. Nutr. Biochem., 2011, 22(10), 902-909.
    • (2011) J. Nutr. Biochem , vol.22 , Issue.10 , pp. 902-909
    • Chung, E.Y.1    Kim, B.H.2    Hong, J.T.3    Lee, C.K.4    Ahn, B.5    Nam, S.6    Han, S.B.7    Kim, Y.8
  • 212
    • 84873474982 scopus 로고    scopus 로고
    • Resveratrol suppresses tumor progression via the regulation of indoleamine 2, 3-dioxygenase
    • Noh, K. T.; Chae, S. H.; Chun, S. H.; Jung, I. D.; Kang, H. K.; Park, Y. M. Resveratrol suppresses tumor progression via the regulation of indoleamine 2, 3-dioxygenase. Biochem. Biophys. Res. Commun., 2013, 431(2), 348-353.
    • (2013) Biochem. Biophys. Res. Commun , vol.431 , Issue.2 , pp. 348-353
    • Noh, K.T.1    Chae, S.H.2    Chun, S.H.3    Jung, I.D.4    Kang, H.K.5    Park, Y.M.6
  • 213
    • 31044449456 scopus 로고    scopus 로고
    • Inhibition of angiotensin converting enzyme activity by flavanol-rich foods
    • Actis-Goretta, L.; Ottaviani, J. I.; Fraga, C. G. Inhibition of angiotensin converting enzyme activity by flavanol-rich foods. J. Agric. Food Chem., 2006, 54, 229-234.
    • (2006) J. Agric. Food Chem , vol.54 , pp. 229-234
    • Actis-Goretta, L.1    Ottaviani, J.I.2    Fraga, C.G.3
  • 214
    • 0031958254 scopus 로고    scopus 로고
    • Insulin stimulation of glucose uptake in skeletal muscles and adipose tissues in vivo is NO dependent
    • Roy, D.; Perreault, M.; Marette, A. Insulin stimulation of glucose uptake in skeletal muscles and adipose tissues in vivo is NO dependent. Am. J. Physiol., 1998, 274, E692-699.
    • (1998) Am. J. Physiol , vol.274 , pp. 692-699
    • Roy, D.1    Perreault, M.2    Marette, A.3
  • 215
    • 0033664017 scopus 로고    scopus 로고
    • Activation of glucose transport by AMPactivated kinase via stimulation of nitric oxide synthesis
    • Fryer, L. G. D.; Hajduch, E.; Rencurel, F.; Salt, I. P.; Hundal, H. S.; Hardie, G.; Carling, D. Activation of glucose transport by AMPactivated kinase via stimulation of nitric oxide synthesis. Diabetes, 2000, 49, 1978-1985.
    • (2000) Diabetes , vol.49 , pp. 1978-1985
    • Fryer, L.G.D.1    Hajduch, E.2    Rencurel, F.3    Salt, I.P.4    Hundal, H.S.5    Hardie, G.6    Carling, D.7
  • 216
    • 0037167677 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase
    • Wallerath, T.; Deckert, G.; Ternes, T.; Anderson, H.; Li, H.; Witte, K.; Förstermann, U. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation, 2002, 106, 1652-1658.
    • (2002) Circulation , vol.106 , pp. 1652-1658
    • Wallerath, T.1    Deckert, G.2    Ternes, T.3    Anderson, H.4    Li, H.5    Witte, K.6    Förstermann, U.7
  • 217
    • 84871712223 scopus 로고    scopus 로고
    • The vasorelaxing effect of resveratrol on abdominal aorta from rats and its underlying mechanisms
    • Shen, M.; Zhao, L.; Wu, R. X.; Yue, S. Q.; Pei, J. M. The vasorelaxing effect of resveratrol on abdominal aorta from rats and its underlying mechanisms. Vascul. Pharmacol., 2013, 58, 64-70.
    • (2013) Vascul. Pharmacol , vol.58 , pp. 64-70
    • Shen, M.1    Zhao, L.2    Wu, R.X.3    Yue, S.Q.4    Pei, J.M.5
  • 218
    • 0030857901 scopus 로고    scopus 로고
    • Exercisestimulated glucose transport in skeletal muscle is nitric oxide dependent
    • Roberts, C. K.; Barnard, R. J.; Scheck, S. H.; Balon, T. W. Exercisestimulated glucose transport in skeletal muscle is nitric oxide dependent. Am. J. Physiol., 1997, 273, E220-225.
    • (1997) Am. J. Physiol , vol.273 , pp. 220-225
    • Roberts, C.K.1    Barnard, R.J.2    Scheck, S.H.3    Balon, T.W.4
  • 219
    • 79955115879 scopus 로고    scopus 로고
    • α-glucosidase inhibitors from plants: A natural approach to treat diabetes
    • Kumar, S.; Narwal, S.; Kumar, V.; Prakash, O. α-glucosidase inhibitors from plants: A natural approach to treat diabetes. Pharmacogn. Rev., 2011, 5, 19-29.
    • (2011) Pharmacogn. Rev , vol.5 , pp. 19-29
    • Kumar, S.1    Narwal, S.2    Kumar, V.3    Prakash, O.4
  • 220
    • 84862619179 scopus 로고    scopus 로고
    • Natural mood foods: The actions of polyphenols against psychiatric and cognitive disorders
    • Gomez-Pinilla, F.; Nguyen, T. T. Natural mood foods: the actions of polyphenols against psychiatric and cognitive disorders. Nutr. Neurosci., 2012, 15, 127-133.
    • (2012) Nutr. Neurosci , vol.15 , pp. 127-133
    • Gomez-Pinilla, F.1    Nguyen, T.T.2
  • 222
    • 84865967160 scopus 로고    scopus 로고
    • A comprehensive review of the carcinogenic and anticarcinogenic potential of capsaicin
    • Bley, K.; Boorman, G.; Mohammad, B.; McKenzie, D.; Babbar, S. A comprehensive review of the carcinogenic and anticarcinogenic potential of capsaicin. Toxicol. Pathol., 2012, 40, 847-873.
    • (2012) Toxicol. Pathol , vol.40 , pp. 847-873
    • Bley, K.1    Boorman, G.2    Mohammad, B.3    McKenzie, D.4    Babbar, S.5
  • 223
    • 84862248921 scopus 로고    scopus 로고
    • Cancer cell signaling pathways targeted by spice-derived nutraceuticals
    • Sung, B.; Prasad, S.; Yadav, V. R.; Aggarwal, B. B. Cancer cell signaling pathways targeted by spice-derived nutraceuticals. Nutr. Cancer, 2012, 64, 173-197.
    • (2012) Nutr. Cancer , vol.64 , pp. 173-197
    • Sung, B.1    Prasad, S.2    Yadav, V.R.3    Aggarwal, B.B.4
  • 226
    • 67349235348 scopus 로고    scopus 로고
    • Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
    • Thomasset, S.; Teller, N.; Cai, H.; Marko, D.; Berry, D. P.; Steward, W. P.; Gescher, A. J. Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? Cancer Chemother. Pharmacol., 2009, 64, 201-211.
    • (2009) Cancer Chemother. Pharmacol , vol.64 , pp. 201-211
    • Thomasset, S.1    Teller, N.2    Cai, H.3    Marko, D.4    Berry, D.P.5    Steward, W.P.6    Gescher, A.J.7
  • 227
    • 80054966931 scopus 로고    scopus 로고
    • Induction of cancer cell death by isoflavone: The role of multiple signaling pathways
    • Li, Y.; Kong, D.; Bao, B.; Ahmad, A.; Sarkar, F. H. Induction of cancer cell death by isoflavone: the role of multiple signaling pathways. Nutrients, 2011, 3, 877-896.
    • (2011) Nutrients , vol.3 , pp. 877-896
    • Li, Y.1    Kong, D.2    Bao, B.3    Ahmad, A.4    Sarkar, F.H.5
  • 228
    • 79952084858 scopus 로고    scopus 로고
    • Dietary polyphenols and obesity
    • Meydani, M.; Hasan, S. T. Dietary polyphenols and obesity. Nutrients, 2011, 2, 737-751.
    • (2011) Nutrients , vol.2 , pp. 737-751
    • Meydani, M.1    Hasan, S.T.2
  • 229
    • 84872857675 scopus 로고    scopus 로고
    • Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans
    • Saito, M.; Yoneshiro, T. Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans. Curr. Opin. Lipidol., 2013, 24, 71-77.
    • (2013) Curr. Opin. Lipidol , vol.24 , pp. 71-77
    • Saito, M.1    Yoneshiro, T.2
  • 230
    • 84874714758 scopus 로고    scopus 로고
    • Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead box O1 mediated upregulation of antioxidant enzymes
    • Higuchi, M.; Dusting, G. J.; Peshavariya, H.; Jiang, F.; Hsiao, S. T.; Chan, E. C.; Liu, G. S. Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead box O1 mediated upregulation of antioxidant enzymes. Stem Cells Dev., 2013, 22, 878-888.
    • (2013) Stem Cells Dev , vol.22 , pp. 878-888
    • Higuchi, M.1    Dusting, G.J.2    Peshavariya, H.3    Jiang, F.4    Hsiao, S.T.5    Chan, E.C.6    Liu, G.S.7
  • 232
    • 0036296295 scopus 로고    scopus 로고
    • Wine flavonoids protect against LDL oxidation and atherosclerosis
    • Aviram, M.; Fuhrman, B. Wine flavonoids protect against LDL oxidation and atherosclerosis. Ann. N. Y. Acad. Sci., 2002, 957, 146-161.
    • (2002) Ann. N.Y. Acad. Sci , vol.957 , pp. 146-161
    • Aviram, M.1    Fuhrman, B.2
  • 233
    • 80052213096 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease
    • Smith, B. W.; Adams, L. A. Non-alcoholic fatty liver disease. Crit. Rev. Clin. Lab. Sci., 2011, 48(3), 97-113.
    • (2011) Crit. Rev. Clin. Lab. Sci , vol.48 , Issue.3 , pp. 97-113
    • Smith, B.W.1    Adams, L.A.2
  • 234
    • 84862777613 scopus 로고    scopus 로고
    • Isoflavones as a smart curer for nonalcoholic fatty liver disease and pathological adiposity via ChREBP and Wnt signaling
    • Kim, M. H.; Kang, K. S. Isoflavones as a smart curer for nonalcoholic fatty liver disease and pathological adiposity via ChREBP and Wnt signaling. Prev. Med., 2012, 54, S57-63.
    • (2012) Prev. Med , vol.54 , pp. 57-63
    • Kim, M.H.1    Kang, K.S.2
  • 235
    • 77955067063 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1
    • Leng, S.; Zhang, W.; Zheng, Y.; Liberman, Z.; Rhodes, C. J.; Eldar-Finkelman, H.; Sun, X. J. Glycogen synthase kinase 3 beta mediates high glucose-induced ubiquitination and proteasome degradation of insulin receptor substrate 1. J. Endocrinol., 2010, 206(2), 171-181.
    • (2010) J. Endocrinol , vol.206 , Issue.2 , pp. 171-181
    • Leng, S.1    Zhang, W.2    Zheng, Y.3    Liberman, Z.4    Rhodes, C.J.5    Eldar-Finkelman, H.6    Sun, X.J.7
  • 236
    • 84887569819 scopus 로고    scopus 로고
    • Antibacterial and antidiarrheal activities of plant products against enterotoxinogenic Escherichia coli
    • Dubreuil, J. D. Antibacterial and antidiarrheal activities of plant products against enterotoxinogenic Escherichia coli. Toxins, 2013, 5, 2009-2041.
    • (2013) Toxins , vol.5 , pp. 2009-2041
    • Dubreuil, J.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.