-
1
-
-
0032416104
-
Molecular chaperones: Biology and prospects for pharmacological intervention
-
Smith, D. F.; Whitesell, L.; Katsanis, E. Molecular Chaperones: Biology and Prospects for Pharmacological Intervention. Pharmacol. Rev. 1998, 50, 493-513.
-
(1998)
Pharmacol. Rev.
, vol.50
, pp. 493-513
-
-
Smith, D.F.1
Whitesell, L.2
Katsanis, E.3
-
2
-
-
0016840757
-
Induced thermal resistance in hela cells
-
Gerner, E. W.; Schneider, M. J. Induced Thermal Resistance in Hela Cells. Nature 1975, 256, 500-502.
-
(1975)
Nature
, vol.256
, pp. 500-502
-
-
Gerner, E.W.1
Schneider, M.J.2
-
3
-
-
0032850421
-
A method for the quantitative an alysis of human heat shock gene expression using a multiplex RT-PCR assay
-
Wang, S. M.; Khandekar, J. D.; Kaul, K. L.; Winchester, D. J.; Morimoto, R. I. A Method for the Quantitative an alysis of Human Heat Shock Gene Expression Using a Multiplex RT-PCR Assay. Cell Stress Chap. 1999, 4, 153-161.
-
(1999)
Cell Stress Chap.
, vol.4
, pp. 153-161
-
-
Wang, S.M.1
Khandekar, J.D.2
Kaul, K.L.3
Winchester, D.J.4
Morimoto, R.I.5
-
4
-
-
0034924812
-
Folding of newly translated proteins in vivo: The role of molecular chaperones
-
Frydman, J. Folding of Newly Translated Proteins in Vivo: the Role of Molecular Chaperones. Annu. Rev. Biochem. 2001, 70, 603-647.
-
(2001)
Annu. Rev. Biochem.
, vol.70
, pp. 603-647
-
-
Frydman, J.1
-
5
-
-
0031873752
-
The 90-Kda molecular chaperone family: Structure, function, and clinical applications. A comprehensive review
-
Csermely, P.; Schnaider, T.; Soti, C.; Prohaskka, Z.; Nardai, G. The 90-Kda Molecular Chaperone Family: Structure, Function, and Clinical Applications. A Comprehensive Review. Pharmacol. Ther. 1998, 79, 129-168.
-
(1998)
Pharmacol. Ther.
, vol.79
, pp. 129-168
-
-
Csermely, P.1
Schnaider, T.2
Soti, C.3
Prohaskka, Z.4
Nardai, G.5
-
6
-
-
3542995049
-
Stress-inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection
-
Morimoto, R. I.; Santoro, M. G. Stress-Inducible Responses and Heat Shock Proteins: New Pharmacologic Targets for Cytoprotection. Nature Biotech. 1998, 16, 833-838.
-
(1998)
Nature Biotech.
, vol.16
, pp. 833-838
-
-
Morimoto, R.I.1
Santoro, M.G.2
-
7
-
-
0035989680
-
Hsp90 as a new therapeutic target for cancer therapy: The story unfolds
-
Maloney, A.; Workman, P. Hsp90 as a New Therapeutic Target for Cancer Therapy: the Story Unfolds. Expert Opin. Biol. Ther. 2002, 2, 3-24.
-
(2002)
Expert Opin. Biol. Ther.
, vol.2
, pp. 3-24
-
-
Maloney, A.1
Workman, P.2
-
8
-
-
0035176758
-
The Hsp90 chaperone as a promising drug target
-
Piper, P. W. The Hsp90 Chaperone as a Promising Drug Target. Curr. Opin. Invest. Drugs 2001, 2, 1606-1610.
-
(2001)
Curr. Opin. Invest. Drugs
, vol.2
, pp. 1606-1610
-
-
Piper, P.W.1
-
9
-
-
0032862606
-
New aspects in the vertebrate heat shock factor system: Hsf3 and Hsf4
-
Nakai, A. New Aspects in the Vertebrate Heat Shock Factor System: Hsf3 and Hsf4. Cell Stress Chap. 1999, 4, 86-93.
-
(1999)
Cell Stress Chap.
, vol.4
, pp. 86-93
-
-
Nakai, A.1
-
10
-
-
0027406535
-
Characterization of a novel chicken heat shock transcription factor, HSF3, suggests a new regulatory pathway
-
Nakai, A.; Morimoto, R. I. Characterization of a Novel Chicken Heat Shock Transcription Factor, HSF3, Suggests a New Regulatory Pathway. Mol. Cell Biol. 1993, 13, 1983-1997.
-
(1993)
Mol. Cell Biol.
, vol.13
, pp. 1983-1997
-
-
Nakai, A.1
Morimoto, R.I.2
-
11
-
-
0025755922
-
Heat shock factor and the heat shock response
-
Sorger, P. K. Heat Shock Factor and the Heat Shock Response. Cell 1991, 65, 363-366.
-
(1991)
Cell
, vol.65
, pp. 363-366
-
-
Sorger, P.K.1
-
12
-
-
0028896839
-
Heat-inducible DNA binding of purified heat shock transcription factor 1
-
Goodson, M. L.; Sarge, K. D. Heat-Inducible DNA Binding of Purified Heat Shock Transcription Factor 1. J. Biol. Chem. 1995, 270, 2447-2450.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2447-2450
-
-
Goodson, M.L.1
Sarge, K.D.2
-
13
-
-
0032780311
-
Heat shock factor function and regulation in response to cellular stress, growth and differentiation signals
-
Morano, K. A.; Thiele, D. J. Heat Shock Factor Function and Regulation in Response to Cellular Stress, Growth and Differentiation Signals. Gene. Exp. 1999, 7, 271-282.
-
(1999)
Gene. Exp.
, vol.7
, pp. 271-282
-
-
Morano, K.A.1
Thiele, D.J.2
-
14
-
-
0030949494
-
Function and regulation of heat shock factor 2 during mouse embryogenesis
-
Rallu, M.; Loones, M. T.; Lallemand, Y.; Morimoto, R. I.; Morange, M.; Mezger, V. Function and Regulation of Heat Shock Factor 2 During Mouse Embryogenesis. Proc. Natl. Acad. Sci. USA 1997, 94, 2392-2397.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 2392-2397
-
-
Rallu, M.1
Loones, M.T.2
Lallemand, Y.3
Morimoto, R.I.4
Morange, M.5
Mezger, V.6
-
15
-
-
0026746491
-
Activation of heat shock factor 2 during hemin-induced differentiation of human erythroleukemnia cells
-
Sistonen, L.; Sarge, K. D.; Phillips, B.; Morimoto, R. I. Activation of Heat Shock Factor 2 During Hemin-Induced Differentiation of Human Erythroleukemnia Cells. Mol. Cell Biol. 1992, 12, 4104-4111.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 4104-4111
-
-
Sistonen, L.1
Sarge, K.D.2
Phillips, B.3
Morimoto, R.I.4
-
16
-
-
0030966628
-
Overexpression of HSF2-Beta inhibits hemin-induced heat shock gene expression and erythroid differentiation in K562 cells
-
Leppa, S.; Pirkkala, L.; Saarento, H.; Sarge, K. D.; Sistonen, L. Overexpression of HSF2-Beta Inhibits Hemin-Induced Heat Shock Gene Expression and Erythroid Differentiation in K562 Cells. J. Biol. Chem. 1997, 272, 15293-15298.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15293-15298
-
-
Leppa, S.1
Pirkkala, L.2
Saarento, H.3
Sarge, K.D.4
Sistonen, L.5
-
17
-
-
0034674061
-
JNK targeting phosphorylation of heat shock factor-1 suppress its transcriptional activity
-
Dai, R.; Frejtag, W.; He, B.; Zhang, Y.; Mivechi, N. F. JNK Targeting and Phosphorylation of Heat Shock Factor-1 Suppress Its Transcriptional Activity. J. Biol. Chem. 2000, 275, 18210-18218.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 18210-18218
-
-
Dai, R.1
Frejtag, W.2
He, B.3
Zhang, Y.4
Mivechi, N.F.5
-
18
-
-
0032535245
-
Regulation of the heat shock transcriptional response: Cross talk between a family of heat shock factors, molecular chaperones, and negative regulators
-
Morimoto, R. I. Regulation of the Heat Shock Transcriptional Response: Cross Talk Between a Family of Heat Shock Factors, Molecular Chaperones, and Negative Regulators. Genes. Devel. 1998, 12, 3788-3796.
-
(1998)
Genes. Devel.
, vol.12
, pp. 3788-3796
-
-
Morimoto, R.I.1
-
19
-
-
17744372861
-
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
-
Pirkkala, L.; Nykanen, P.; Sistonen, L. Roles of the Heat Shock Transcription Factors in Regulation of the Heat Shock Response and Beyond. FASEB J. 2001, 15, 1118-1131.
-
(2001)
FASEB J.
, vol.15
, pp. 1118-1131
-
-
Pirkkala, L.1
Nykanen, P.2
Sistonen, L.3
-
20
-
-
0032571397
-
Targeted disruption of heat shock transcription factor 1 abolishes thermotolerance and protection against heat-inducible apoptosis
-
Mcmillan, D. R.; Xiao, X.; Shao, L.; Graves, K.; Benjamin, I. J. Targeted Disruption of Heat Shock Transcription Factor 1 Abolishes Thermotolerance and Protection against Heat-Inducible Apoptosis. J. Biol. Chem. 1998, 273, 7523-7528.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7523-7528
-
-
Mcmillan, D.R.1
Xiao, X.2
Shao, L.3
Graves, K.4
Benjamin, I.J.5
-
21
-
-
0033229880
-
HSF1 Is required for extra-embryonic development, postnatal growth and protection during inflammatory responses in mice
-
Xiao, X.; Zuo, X.; Davis, A. A.; Mcmillan, D. R.; Curry, B. B.; Richardson, J. A.; Benjamin, I. J. HSF1 Is Required for Extra-Embryonic Development, Postnatal Growth and Protection During Inflammatory Responses in Mice. EMBO J. 1999, 18, 5943-5952.
-
(1999)
EMBO J.
, vol.18
, pp. 5943-5952
-
-
Xiao, X.1
Zuo, X.2
Davis, A.A.3
Mcmillan, D.R.4
Curry, B.B.5
Richardson, J.A.6
Benjamin, I.J.7
-
22
-
-
0030988941
-
Repression of the heat shock factor 1 transcriptional activation domain is modulated by constitutive phosphorylation
-
Kline, M. P.Morimoto, R. I. Repression of the Heat Shock Factor 1 Transcriptional Activation Domain Is Modulated by Constitutive Phosphorylation. Mol. Cell Biol. 1997, 17, 2107-2115.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 2107-2115
-
-
Kline, M.P.1
Morimoto, R.I.2
-
23
-
-
0032541032
-
Transcriptional activity of heat shock factor 1 at 37 degrees C is repressed through phosphorylation on two distinct serine residues by glycogen synthase kinase 3 and protein kinases calpha and czeta
-
Chu, B.; Zhong, R.; Soncin, F.; Stevenson, M. A.; Calderwood, S. K. Transcriptional Activity of Heat Shock Factor 1 At 37 Degrees C Is Repressed Through Phosphorylation on Two Distinct Serine Residues by Glycogen Synthase Kinase 3 and Protein Kinases Calpha and Czeta. J. Biol. Chem. 1998, 273, 18640-18646.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 18640-18646
-
-
Chu, B.1
Zhong, R.2
Soncin, F.3
Stevenson, M.A.4
Calderwood, S.K.5
-
24
-
-
0032555685
-
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 Complex) that forms a stress-sensitive complex with HSF1
-
Zou, J.; Guo, Y.; Guettouche, T.; Smith, D. F.; Voellmy, R. Repression of Heat Shock Transcription Factor HSF1 Activation by HSP90 (HSP90 Complex) That Forms a Stress-Sensitive Complex with HSF1. Cell 1998, 94, 471-480.
-
(1998)
Cell
, vol.94
, pp. 471-480
-
-
Zou, J.1
Guo, Y.2
Guettouche, T.3
Smith, D.F.4
Voellmy, R.5
-
25
-
-
0031866191
-
HSP90 interacts with and regulates the activity of heat shock factor 1 in xenopus oocytes
-
Ali, A.; Bharadwaj, S.; O'Carroll, R.; Ovsenek, N. HSP90 Interacts with and Regulates the Activity of Heat Shock Factor 1 in Xenopus Oocytes. Mol. Cell Biol. 1998, 18, 4949-4960.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 4949-4960
-
-
Ali, A.1
Bharadwaj, S.2
O'Carroll, R.3
Ovsenek, N.4
-
26
-
-
0033499798
-
Multiple components of the HSP90 chaperone complex function in regulation of heat shock factor 1 in vivo
-
Bharadwaj, S.; Ali, A.; Ovsenek, N. Multiple Components of the HSP90 Chaperone Complex Function in Regulation of Heat Shock Factor 1 in Vivo. Mol. Cell Biol. 1999, 19, 8033-8041.
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 8033-8041
-
-
Bharadwaj, S.1
Ali, A.2
Ovsenek, N.3
-
27
-
-
0030324952
-
A pathway of multi-chaperone interactions common to diverse regulatory proteins estrogen receptor, fes tyrosine kinase, heat shock transcription factor HSF1, and the aryl hydrocarbon receptor
-
Nair, S. C.; Toran, E. J.; Rimerman, R. A.; Hjermstad, S.; Smithgall, T. E.; Smith, D. F. A Pathway of Multi-Chaperone Interactions Common to Diverse Regulatory Proteins: Estrogen Receptor, Fes Tyrosine Kinase, Heat Shock Transcription Factor HSF1, and the Aryl Hydrocarbon Receptor. Cell Stress Chap. 1996, 1, 237-250.
-
(1996)
Cell Stress Chap.
, vol.1
, pp. 237-250
-
-
Nair, S.C.1
Toran, E.J.2
Rimerman, R.A.3
Hjermstad, S.4
Smithgall, T.E.5
Smith, D.F.6
-
28
-
-
0027475243
-
Hsp90 chaperonins possess atpase activity and bind heat shock transcription factors and peptidyl prolyl isomerases
-
Nadeau, K.; Das, A.; Walsh, C. T. Hsp90 Chaperonins Possess Atpase Activity and Bind Heat Shock Transcription Factors and Peptidyl Prolyl Isomerases. J. Biol. Chem. 1993, 268, 1479-1487.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1479-1487
-
-
Nadeau, K.1
Das, A.2
Walsh, C.T.3
-
29
-
-
0030043401
-
Activation of heat shock factor 1 DNA biniding precedes stress-induced serine phosphorylation
-
Cotto, J. J.; Kline, M.; Morimoto, R. I. Activation of Heat Shock Factor 1 DNA Biniding Precedes Stress-Induced Serine Phosphorylation. J. Biol. Chem. 1996, 271, 3355-3358.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3355-3358
-
-
Cotto, J.J.1
Kline, M.2
Morimoto, R.I.3
-
30
-
-
0031055277
-
Hyperphosphorylation of heat shock transcription factor 1 is correlated with transcriptional competence and slow dissociation of active factor trimers
-
Xia, W.; Voellmy, R. Hyperphosphorylation of Heat Shock Transcription Factor 1 Is Correlated with Transcriptional Competence and Slow Dissociation of Active Factor Trimers. J. Biol. Chem. 1997, 272, 4094-4102.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 4094-4102
-
-
Xia, W.1
Voellmy, R.2
-
31
-
-
0035955662
-
Regulation of heat shock transcription factor 1 by stress-induced SUMO-I modification
-
Hong, Y.; Rogers, R.; Matunis, M. J.; Mayhew, C. N.; Goodson, M.; Park-Sarge, O. K.; Sarge, K. D. Regulation of Heat Shock Transcription Factor 1 by Stress-Induced SUMO-I Modification. J. Biol. Chem. 2001, 276, 40263-40267.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40263-40267
-
-
Hong, Y.1
Rogers, R.2
Matunis, M.J.3
Mayhew, C.N.4
Goodson, M.5
Park-Sarge, O.K.6
Sarge, K.D.7
-
32
-
-
0032612322
-
Stress-induced activation of the heat-shock response: Cell and molecular biology of heat-shock factors
-
Cotto, J. J.; Morimoto, R. I. Stress-Induced Activation of the Heat-Shock Response: Cell and Molecular Biology of Heat-Shock Factors. Biochem. Soc. Symp. 1999, 64, 105-118.
-
(1999)
Biochem. Soc. Symp.
, vol.64
, pp. 105-118
-
-
Cotto, J.J.1
Morimoto, R.I.2
-
33
-
-
0032031725
-
Molecular chaperones as HSF1-Specific transcriptional repressors
-
Shi, Y.; Mosser, D. D.; Morimoto, R. I. Molecular Chaperones as HSF1-Specific Transcriptional Repressors. Genes. Devel. 1998, 12, 654-666.
-
(1998)
Genes. Devel.
, vol.12
, pp. 654-666
-
-
Shi, Y.1
Mosser, D.D.2
Morimoto, R.I.3
-
34
-
-
0035824621
-
Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex
-
Guo, Y.; Guettouche, T.; Fenna, M.; Boellmann, F.; Pratt, W. B.; to ft, D. O.; Smith, D. F.; Voellmy, R. Evidence for a Mechanism of Repression of Heat Shock Factor 1 Transcriptional Activity by a Multichaperone Complex. J. Biol. Chem. 2001, 276, 45791-45799.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45791-45799
-
-
Guo, Y.1
Guettouche, T.2
Fenna, M.3
Boellmann, F.4
Pratt, W.B.5
Toft, D.O.6
Smith, D.F.7
Voellmy, R.8
-
35
-
-
0028847062
-
Short circuiting stress protein expression via a tyrosine kinase inhibitor, herbimycin A
-
Hegde, R.; Zuo, J.; Voellmy, R.; Welch, W. Short Circuiting Stress Protein Expression Via a Tyrosine Kinase Inhibitor, Herbimycin A. J. Cell Physiol. 1995, 165, 186.
-
(1995)
J. Cell Physiol.
, vol.165
, pp. 186
-
-
Hegde, R.1
Zuo, J.2
Voellmy, R.3
Welch, W.4
-
36
-
-
0025744556
-
Induction of Hsp72/73 by herbimycin A, an inhibitor of transformation by tyrosine kinase oncogenes
-
Murakami, Y.; Uehara, Y.; Yamamoto, C.; Fukazawa, H.; Mizuno, S. Induction of Hsp72/73 by Herbimycin A, an Inhibitor of Transformation by Tyrosine Kinase Oncogenes. Exp. Cell Res. 1991, 195, 338-344.
-
(1991)
Exp. Cell Res.
, vol.195
, pp. 338-344
-
-
Murakami, Y.1
Uehara, Y.2
Yamamoto, C.3
Fukazawa, H.4
Mizuno, S.5
-
37
-
-
0033890818
-
Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of Hsp90 binding agents
-
Bagatell, R.; Paine-Murrieta, G.; Taylor, C.; Pulcini, E.; Akinaga, S.; Benjamin, I.; Whitesell, L. Induction of a Heat Shock Factor 1-Dependent Stress Response Alters the Cytotoxic Activity of Hsp90 Binding Agents. Clin. Cancer Res. 2000, 6, 3312-3318.
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3312-3318
-
-
Bagatell, R.1
Paine-Murrieta, G.2
Taylor, C.3
Pulcini, E.4
Akinaga, S.5
Benjamin, I.6
Whitesell, L.7
-
38
-
-
0031006855
-
Xenopus heat shock factor 1 is a nuclear protein before heat stress
-
Mercier, P. A.; Foksa, J.; Ovsenek, N.; Westwood, J. T. Xenopus Heat Shock Factor 1 Is a Nuclear Protein Before Heat Stress. J. Biol. Chem. 1997, 272, 14147-14151.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14147-14151
-
-
Mercier, P.A.1
Foksa, J.2
Ovsenek, N.3
Westwood, J.T.4
-
39
-
-
0033536006
-
Rapid and reversible relocalization of heat shock factor 1 within seconds to nuclear stress granules
-
Jolly, C.; Usson, Y.; Morimoto, R. I. Rapid and Reversible Relocalization of Heat Shock Factor 1 Within Seconds to Nuclear Stress Granules. Proc. Natl. Acad. Sci. USA 1999, 96, 6769-6774.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6769-6774
-
-
Jolly, C.1
Usson, Y.2
Morimoto, R.I.3
-
40
-
-
0030878952
-
Geldanamycin-stmulated destabilization of mutated p53 is mediated by the proteasome in vivo
-
Whitesell, L.; Sutphin, P.; An, W. G.; Schulte, T.; Blagosklonny, M. V.; Neckers, L. Geldanamycin-Stmulated Destabilization of Mutated p53 is Mediated by the Proteasome in vivo. Oncogene 1997, 14, 2809-2816.
-
(1997)
Oncogene
, vol.14
, pp. 2809-2816
-
-
Whitesell, L.1
Sutphin, P.2
An, W.G.3
Schulte, T.4
Blagosklonny, M.V.5
Neckers, L.6
-
41
-
-
0029963674
-
U pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90
-
Schneider, C.; Sepp-Lorenzino, L.; Nimmesgern, E.; Ouerfelli, O.; Danishefsky, S.; Rosen, N.; Hartl, F. U, Pharmacologic Shifting of a Balance Between Protein Refolding and Degradation Mediated by Hsp90. Proc. Natl. Acad. Sci. USA 1996, 93, 14536-14541.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14536-14541
-
-
Schneider, C.1
Sepp-Lorenzino, L.2
Nimmesgern, E.3
Ouerfelli, O.4
Danishefsky, S.5
Rosen, N.6
Hartl, F.7
-
42
-
-
0035490924
-
Proteasome inhibitors differentially affect heat shock protein response in cancer cells
-
Ashok, B. T.; Kim, E.; Mittelman, A.; Tiwari, R. K. Proteasome Inhibitors Differentially Affect Heat Shock Protein Response in Cancer Cells. Int. J. MoL Med. 2001, 8, 385-390.
-
(2001)
Int. J. MoL Med.
, vol.8
, pp. 385-390
-
-
Ashok, B.T.1
Kim, E.2
Mittelman, A.3
Tiwari, R.K.4
-
43
-
-
0037022365
-
Complementary whole-genome technologies reveal the cellular response to proteasome inhibition by PS-341
-
Fleming, J. A.; Lightcap, E. S.; Sadis, S.; Thoroddsen, V.; Bulawa, C. E.; Blackman, R. K. Complementary Whole-Genome Technologies Reveal the Cellular Response to Proteasome Inhibition by PS-341. Proc. Natl. Acad. Sci. USA 2002, 99, 1461-1466.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1461-1466
-
-
Fleming, J.A.1
Lightcap, E.S.2
Sadis, S.3
Thoroddsen, V.4
Bulawa, C.E.5
Blackman, R.K.6
-
44
-
-
4243592951
-
Biologic rationale for the combination of an Hsp90 an tagonist with a proteasome inhibitor
-
Mimnaugh, E. G.; Neckers, L. Biologic Rationale for the Combination of an Hsp90 an tagonist with a Proteasome Inhibitor. Clin. Cancer Res. 2001, 7 (Supplement), 3779s.
-
(2001)
Clin. Cancer Res.
, vol.7
, Issue.SUPPL.
-
-
Mimnaugh, E.G.1
Neckers, L.2
-
45
-
-
17844386323
-
Phosphorylation of serine 230 promotes inducible transcriptional activity of heat shock factor 1
-
Holmberg, C. I.; Hietakangas, V.; Mikhailov, A.; Rantanen, J. O.; Kallio, M.; Meinander, A.; Hellman, J.; Morrice, N.; Mackintosh, C.; Morimoto, R. I.; Eriksson, J. E.; Sistonen, L. Phosphorylation of Serine 230 Promotes Inducible Transcriptional Activity of Heat Shock Factor 1. EMBO J. 2001, 20, 3800-3810.
-
(2001)
EMBO J.
, vol.20
, pp. 3800-3810
-
-
Holmberg, C.I.1
Hietakangas, V.2
Mikhailov, A.3
Rantanen, J.O.4
Kallio, M.5
Meinander, A.6
Hellman, J.7
Morrice, N.8
Mackintosh, C.9
Morimoto, R.I.10
Eriksson, J.E.11
Sistonen, L.12
-
46
-
-
0037067712
-
Geldanamycin leads to superoxide formation by enzymatic and non-enzymatic redox cycling. Implications for studies of Hsp90 and endothelial cell nitric-oxide synthase
-
Dikalov, S.; Landmesser, U.; Harrison, D. G. Geldanamycin Leads to Superoxide Formation by Enzymatic and Non-Enzymatic Redox Cycling. Implications for Studies of Hsp90 and Endothelial Cell Nitric-Oxide Synthase. J. Biol. Chem. 2002, 277, 25480-25485.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25480-25485
-
-
Dikalov, S.1
Landmesser, U.2
Harrison, D.G.3
-
47
-
-
0031844350
-
Antibiotic radicicol binds to the N-terminal domain of Hsp90 and shares important biologic activities with geldanamycin
-
Schulte, T. W.; Akinaga, S.; Soga, S.; Sullivan, W.; Stensgard, B.; Toft, D.; Neckers, L. M. Antibiotic Radicicol Binds to the N-Terminal Domain of Hsp90 and Shares Important Biologic Activities with Geldanamycin. Cell Stress Chap. 1998, 3, 100-108.
-
(1998)
Cell Stress Chap.
, vol.3
, pp. 100-108
-
-
Schulte, T.W.1
Akinaga, S.2
Soga, S.3
Sullivan, W.4
Stensgard, B.5
Toft, D.6
Neckers, L.M.7
-
48
-
-
0031891726
-
Geldanamycin, an Hsp90/GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway
-
Lawson, B.; Brewer, J. W.; Hendershot, L. M. Geldanamycin, an Hsp90/GRP94-Binding Drug, Induces Increased Transcription of Endoplasmic Reticulum (ER) Chaperones Via the ER Stress Pathway. J. Cell Physiol. 1998, 174, 170-178.
-
(1998)
J. Cell Physiol.
, vol.174
, pp. 170-178
-
-
Lawson, B.1
Brewer, J.W.2
Hendershot, L.M.3
-
49
-
-
0035966320
-
The unfolding tale of the unfolded protein response
-
Ma, Y.; Hendershot, L. M. The Unfolding Tale of the Unfolded Protein Response. Cell 2001, 107, 827-830.
-
(2001)
Cell
, vol.107
, pp. 827-830
-
-
Ma, Y.1
Hendershot, L.M.2
-
50
-
-
0027251913
-
Correlation of the survival of ovarian cancer patients with mrna expression of the 60kda heat shock protein Hsp60
-
Kimura, E.; Erns, R. E.; Alcaraz, J. E.; Arboleda, J.; Slamon, D. J.; Howell, S. B. Correlation of the Survival of Ovarian Cancer Patients with Mrna Expression of the 60kda Heat Shock Protein Hsp60. J. Clin. Oncol. 1993, 11, 891-898.
-
(1993)
J. Clin. Oncol.
, vol.11
, pp. 891-898
-
-
Kimura, E.1
Erns, R.E.2
Alcaraz, J.E.3
Arboleda, J.4
Slamon, D.J.5
Howell, S.B.6
-
51
-
-
0027503365
-
Heat shock protein Hsp70 in patients with axillary lymph node-negative breast cancer: Prognostic implications
-
Ciocca, D. R.; Clark, G. M.; Tandon, A. K.; Fuqua, S. A. W.; Welch, W. J.; Mcguire, W. L. Heat Shock Protein Hsp70 in Patients with Axillary Lymph Node- Negative Breast Cancer: Prognostic Implications. J. Natl. Cancer Inst. 1993, 85, 570-574.
-
(1993)
J. Natl. Cancer Inst.
, vol.85
, pp. 570-574
-
-
Ciocca, D.R.1
Clark, G.M.2
Tandon, A.K.3
Fuqua, S.A.W.4
Welch, W.J.5
Mcguire, W.L.6
-
52
-
-
0032058966
-
Autoantibodies to the 90kda heat shock protein and poor survival in breast cancer patients
-
Conroy, S. E.; Sasieni, P. D.; Fentiman, I.; Latchman, D. S. Autoantibodies to the 90kda Heat Shock Protein and Poor Survival in Breast Cancer Patients. Eur. J. Cancer 1998, 34, 942-943.
-
(1998)
Eur. J. Cancer
, vol.34
, pp. 942-943
-
-
Conroy, S.E.1
Sasieni, P.D.2
Fentiman, I.3
Latchman, D.S.4
-
53
-
-
0028970484
-
Differential expression of Mr 70,000 heat shock protein in normal, premalignant, and malignant human uterine cervix
-
Ralhan, R.; Kaur, J. Differential Expression of Mr 70,000 Heat Shock Protein in Normal, Premalignant, and Malignant Human Uterine Cervix. Clin. Cancer Res. 1995, 1, 1217-1222.
-
(1995)
Clin. Cancer Res.
, vol.1
, pp. 1217-1222
-
-
Ralhan, R.1
Kaur, J.2
-
54
-
-
0029642276
-
Differential expression of 70-Kda heat shock-protein in human oral tumorigenesis
-
Kaur, J.; Ralhan, R. Differential Expression of 70-Kda Heat Shock-Protein in Human Oral Tumorigenesis. Int. J Cancer 1995, 63, 774-779.
-
(1995)
Int. J Cancer
, vol.63
, pp. 774-779
-
-
Kaur, J.1
Ralhan, R.2
-
55
-
-
0030750217
-
Expression of heat shock protein 72 in renal cell carcinoma: Possible role and prognostic implications in cancer patients
-
Santarosa, M.; Favaro, D.; Quaia, M.; Galligioni, E. Expression of Heat Shock Protein 72 in Renal Cell Carcinoma: Possible Role and Prognostic Implications in Cancer Patients. Euro. J. Cancer. 1997, 33, 873-877.
-
(1997)
Euro. J. Cancer
, vol.33
, pp. 873-877
-
-
Santarosa, M.1
Favaro, D.2
Quaia, M.3
Galligioni, E.4
-
56
-
-
0029011834
-
Analysis of heat shock protein expression in myeloid leukaemia cells by flow cytometry
-
Chant, I. D.; Rose, P. E.; Morris, A. G. an alysis of Heat Shock Protein Expression in Myeloid Leukaemia Cells by Flow Cytometry. Br. J. Haematol. 1995, 90, 163-168.
-
(1995)
Br. J. Haematol.
, vol.90
, pp. 163-168
-
-
Chant, I.D.1
Rose, P.E.2
Morris, A.G.3
-
57
-
-
0026664393
-
High constitutive expression of heat shock protein 90a in human acute leukemia cells
-
Yufu, Y.; Nishimura, J.; Nawata, H. High Constitutive Expression of Heat Shock Protein 90a in Human Acute Leukemia Cells. Leuk. Res. 1992, 16, 597-605.
-
(1992)
Leuk. Res.
, vol.16
, pp. 597-605
-
-
Yufu, Y.1
Nishimura, J.2
Nawata, H.3
-
58
-
-
0026544498
-
Clinical and biological significance of Hsp90a in human breast cancer
-
Jameel, A.; Skilton, R. A.; Campbell, T. A.; Chander, S. K.; Coombes, R. C.; Luqmani, Y. A. Clinical and Biological Significance of Hsp90a in Human Breast Cancer. Int. J. Cancer 1992, 50, 409-415.
-
(1992)
Int. J. Cancer
, vol.50
, pp. 409-415
-
-
Jameel, A.1
Skilton, R.A.2
Campbell, T.A.3
Chander, S.K.4
Coombes, R.C.5
Luqmani, Y.A.6
-
59
-
-
0029849363
-
Expression and roles of heat shock proteins in human breast cancer
-
Yano, M.; Naito, Z.; Tanaka, S.; Asano, G. Expression and Roles of Heat Shock Proteins in Human Breast Cancer. Jpn. J. Cancer Res. 1996, 87, 908-915.
-
(1996)
Jpn. J. Cancer Res.
, vol.87
, pp. 908-915
-
-
Yano, M.1
Naito, Z.2
Tanaka, S.3
Asano, G.4
-
60
-
-
0031733457
-
Prognostic significance of heat shock proteins HSP70 and HSP90 in endometrial carcinomas
-
Nanbu, K.; Konishi, I.; Mandai, M.; Kuroda, H.; Hamid, A. A.; Komatsu, T.; Mori, T. Prognostic Significance of Heat Shock Proteins HSP70 and HSP90 in Endometrial Carcinomas. Cancer Detection & Prevention, 1998, 22, 549-555.
-
(1998)
Cancer Detection & Prevention
, vol.22
, pp. 549-555
-
-
Nanbu, K.1
Konishi, I.2
Mandai, M.3
Kuroda, H.4
Hamid, A.A.5
Komatsu, T.6
Mori, T.7
-
61
-
-
0033988478
-
Antibodies to heat shock protein 90 in osteosarcoma patients correlate with response to neoadjuvant chemotherapy
-
Trieb, K.; Gerth, R.; Holzer, G.; Grohs, J. G.; Berger, P.; Kotz, R. an tibodies to Heat Shock Protein 90 in Osteosarcoma Patients Correlate with Response to Neoadjuvant Chemotherapy. Br. J. Cancer 2000, 82, 85-87.
-
(2000)
Br. J. Cancer
, vol.82
, pp. 85-87
-
-
Trieb, K.1
Gerth, R.2
Holzer, G.3
Grohs, J.G.4
Berger, P.5
Kotz, R.6
-
62
-
-
0038668000
-
Escaping cell death: Survival proteins in cancer
-
Jaattela, M. Escaping Cell Death: Survival Proteins in Cancer. Exp. Cell Res. 1999, 248, 30-43.
-
(1999)
Exp. Cell Res.
, vol.248
, pp. 30-43
-
-
Jaattela, M.1
-
63
-
-
0030999750
-
Apoptosis and the dilemma of cancer chemotherapy
-
Hannun, Y. Apoptosis and the Dilemma of Cancer Chemotherapy. Blood 1997, 89, 1845-1853.
-
(1997)
Blood
, vol.89
, pp. 1845-1853
-
-
Hannun, Y.1
-
64
-
-
0030016274
-
Drug resistance against gemcitabine and topotecan mediated by constitutive Hsp70 overexpression in vitro: Implication of quercetin as sensitizer in chemotherapy
-
Sliutz, G.; Karlseder, J.; Tempfer, C.; Orel, L.; Holzer, G.; Simon, M. M. Drug Resistance against Gemcitabine and Topotecan Mediated by Constitutive Hsp70 Overexpression in Vitro: Implication of Quercetin as Sensitizer in Chemotherapy. Br. J. Cancer 1996, 74, 172-177.
-
(1996)
Br. J. Cancer
, vol.74
, pp. 172-177
-
-
Sliutz, G.1
Karlseder, J.2
Tempfer, C.3
Orel, L.4
Holzer, G.5
Simon, M.M.6
-
65
-
-
0034253533
-
Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the apaf-1 apoptosome
-
Beere, H. M.; Wolf, B. B.; Cain, K.; Mosser, D. D.; Mahboubi, A.; Kuwana, T.; Tailor, P.; Morimoto, R. I.; Cohen, G. M.; Green, D. R. Heat-Shock Protein 70 Inhibits Apoptosis by Preventing Recruitment of Procaspase-9 to the Apaf-1 Apoptosome. Nature Cell Biol. 2000, 2, 469-475.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 469-475
-
-
Beere, H.M.1
Wolf, B.B.2
Cain, K.3
Mosser, D.D.4
Mahboubi, A.5
Kuwana, T.6
Tailor, P.7
Morimoto, R.I.8
Cohen, G.M.9
Green, D.R.10
-
66
-
-
0034253474
-
Negative regulation of the Apaf-1 apoptosome by Hsp70
-
Saleh, A.; Srinivasula, S. M.; Balkir, L.; Robbins, P. D.; Alnemri, E. S. Negative Regulation of the Apaf-1 Apoptosome by Hsp70. Nature Cell Biol. 2000, 2, 476-483.
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 476-483
-
-
Saleh, A.1
Srinivasula, S.M.2
Balkir, L.3
Robbins, P.D.4
Alnemri, E.S.5
-
67
-
-
0033830374
-
The chaperone function of Hsp70 is required for protection against stress-induced apoptosis
-
Mosser, D. D.; Caron, A. W.; Bourget, L.; Meriin, A. B.; Sherman, M. Y.; Morimoto, R. I.; Massie, B. The Chaperone Function of Hsp70 Is Required for Protection against Stress-Induced Apoptosis. Mol. Cell Biol. 2000, 20, 7146-7159.
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 7146-7159
-
-
Mosser, D.D.1
Caron, A.W.2
Bourget, L.3
Meriin, A.B.4
Sherman, M.Y.5
Morimoto, R.I.6
Massie, B.7
-
68
-
-
0034608892
-
Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2
-
Nylandsted, J.; Rohde, M.; Brand, K.; Bastholm, L.; Elling, F.; Jaattela, M. Selective Depletion of Heat Shock Protein 70 (Hsp70) Activates a Tumor-Specific Death Program That Is Independent of Caspases and Bypasses Bcl-2. Proc. Natl. Acad. Sci. USA 2000, 97, 7871-7876.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7871-7876
-
-
Nylandsted, J.1
Rohde, M.2
Brand, K.3
Bastholm, L.4
Elling, F.5
Jaattela, M.6
-
69
-
-
0030667932
-
In vivo functions of the saccharomyces cerevisiae Hsp90 chaperone
-
Nathan, D. E.; Vos, M. H.; Lindquist, S. in Vivo Functions of the Saccharomyces Cerevisiae Hsp90 Chaperone. Proc. Natl. Acad Sci. USA 1997, 94, 12949-12956.
-
(1997)
Proc. Natl. Acad Sci. USA
, vol.94
, pp. 12949-12956
-
-
Nathan, D.E.1
Vos, M.H.2
Lindquist, S.3
-
70
-
-
0031895351
-
The Hsp90-based chaperone system: Involvement in signal transduction from a variety of hormone and growth factor receptors
-
Pratt, W. B. The Hsp90-Based Chaperone System: Involvement in Signal Transduction From a Variety of Hormone and Growth Factor Receptors. Proc. Soc. Exp. Biol. Med. 1998, 217, 420-431.
-
(1998)
Proc. Soc. Exp. Biol. Med.
, vol.217
, pp. 420-431
-
-
Pratt, W.B.1
-
71
-
-
0037047429
-
Dynamic remodeling of transcription complexes by molecular chaperones
-
Morimoto, R. I. Dynamic Remodeling of Transcription Complexes by Molecular Chaperones. Cell 2002, 110, 281-284.
-
(2002)
Cell
, vol.110
, pp. 281-284
-
-
Morimoto, R.I.1
-
72
-
-
0027484097
-
Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes
-
Smith, D. F. Dynamics of Heat Shock Protein 90-Progesterone Receptor Binding and the Disactivation Loop Model for Steroid Receptor Complexes. Mol. Endo. 1993, 7, 1418-1429.
-
(1993)
Mol. Endo.
, vol.7
, pp. 1418-1429
-
-
Smith, D.F.1
-
73
-
-
0028064940
-
Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone an samycins: Essential role for stress proteins in oncogenic transformation
-
Whitesell, L.; Mimnaugh, E. G.; De Costa, B.; Myers, C. E.; Neckers, L. M. Inhibition of Heat Shock Protein HSP90-Pp60v-Src Heteroprotein Complex Formation by Benzoquinone an samycins: Essential Role for Stress Proteins in Oncogenic Transformation. Proc. Natl. Acad. Sci. USA 1994, 91, 8324-8328.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8324-8328
-
-
Whitesell, L.1
Mimnaugh, E.G.2
De Costa, B.3
Myers, C.E.4
Neckers, L.M.5
-
74
-
-
0031909866
-
The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an Hsp90-binding agent
-
Whitesell, L.; Sutphin, P. D.; Pulcini, E. J.; Martinez, J. D.; Cook, P. H. The Physical Association of Multiple Molecular Chaperone Proteins with Mutant p53 Is Altered by Geldanamycin, an Hsp90-Binding Agent. Mol. Cell Biol. 1998, 18, 1517-1524.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 1517-1524
-
-
Whitesell, L.1
Sutphin, P.D.2
Pulcini, E.J.3
Martinez, J.D.4
Cook, P.H.5
-
75
-
-
0029737509
-
Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90
-
Blagosklonny, M. V.; to retsky, J.; Bohen, S.; Neckers, L. Mutant Conformation of p53 Translated in Vitro or in Vivo Requires Functional HSP90. Proc. Natl. Acad. Sci. USA 1996, 93, 8379-8383.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8379-8383
-
-
Blagosklonny, M.V.1
Toretsky, J.2
Bohen, S.3
Neckers, L.4
-
76
-
-
15844363948
-
Heat shock protein 84 forms a complex with mutant p53 protein predominantly within a cytoplasmic compartment of the cell
-
Sepehrnia, B.; Paz, I. B.; Dasgupta, G.; Momand, J. Heat Shock Protein 84 Forms a Complex with Mutant p53 Protein Predominantly within a Cytoplasmic Compartment of the Cell. J. Biol. Chem. 1996, 271, 15084-15090.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15084-15090
-
-
Sepehrnia, B.1
Paz, I.B.2
Dasgupta, G.3
Momand, J.4
-
77
-
-
0032569851
-
Hsp90 as a capacitor for morphological evolution
-
Rutherford, S. L.; Lindquist, S. Hsp90 as a Capacitor for Morphological Evolution. Nature 1998, 396, 336-342.
-
(1998)
Nature
, vol.396
, pp. 336-342
-
-
Rutherford, S.L.1
Lindquist, S.2
-
78
-
-
0037030713
-
Hsp90 as a capacitor of phenotypic variation
-
Queitsch, C.; Sangster, T. A.; Lindquist, S. Hsp90 as a Capacitor of Phenotypic Variation. Nature 2002, 417, 618-624.
-
(2002)
Nature
, vol.417
, pp. 618-624
-
-
Queitsch, C.1
Sangster, T.A.2
Lindquist, S.3
-
79
-
-
0017748765
-
Geldanamycin inhibition of 3-methylcholanthrene-induced rat embryo cell transformation
-
Price, P. J.; Suk, W. A.; Skeen, P. C.; Spahn, G. J.; Chirigos, M. A. Geldanamycin Inhibition of 3-Methylcholanthrene-Induced Rat Embryo Cell Transformation. Proc. Soc. Exp. Biol. Med. 1977, 155, 461-463.
-
(1977)
Proc. Soc. Exp. Biol. Med.
, vol.155
, pp. 461-463
-
-
Price, P.J.1
Suk, W.A.2
Skeen, P.C.3
Spahn, G.J.4
Chirigos, M.A.5
-
80
-
-
0034710542
-
Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the Hsp90 molecular chaperone
-
Clarke, P. A.; Hostein, I.; Bancrji, U.; Stefano, F. D.; Maloney, A.; Walton, M.; Judson, I.; Workman, P. Gene Expression Profiling of Human Colon Cancer Cells Following Inhibition of Signal Transduction by 17-Allylamino-17-Demethoxygeldanamycin, an Inhibitor of the Hsp90 Molecular Chaperone. Oncogene 2000, 19, 4125-4133.
-
(2000)
Oncogene
, vol.19
, pp. 4125-4133
-
-
Clarke, P.A.1
Hostein, I.2
Bancrji, U.3
Stefano, F.D.4
Maloney, A.5
Walton, M.6
Judson, I.7
Workman, P.8
-
81
-
-
0032541344
-
ATP binding hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo
-
Panaretou, B.; Prodromou, C.; Roe, S. M.; O'Brien, R.; Ladbury, J. E.; Piper, P. W.; Pearl, L. H. ATP Binding and Hydrolysis Are Essential to the Function of the Hsp90 Molecular Chaperone in Vivo. EMBO J. 1998, 17, 4829-4836.
-
(1998)
EMBO J.
, vol.17
, pp. 4829-4836
-
-
Panaretou, B.1
Prodromou, C.2
Roe, S.M.3
O'Brien, R.4
Ladbury, J.E.5
Piper, P.W.6
Pearl, L.H.7
-
82
-
-
0038619054
-
Assays for Hsp90 and inhibitors
-
Buolamwini J. K.; Adjei, A. A., Eds.; Humana Press: Totowa, NJ
-
Aherne, W.; Maloney, A.; Prodromou, C; Rowlands, M. G.; Hardcastle, A.; Boxall, K.; Clarke, P.; Walton, M.; Pearl, L.; Workman, P. Assays for Hsp90 and Inhibitors. In Novel Anticancer Drug Protocols, Methods in Molecular Medicine Vol. 85; Buolamwini J. K.; Adjei, A. A., Eds.; Humana Press: Totowa, NJ, 2003, pp.
-
(2003)
Novel Anticancer Drug Protocols, Methods in Molecular Medicine Vol. 85
, vol.85
-
-
Aherne, W.1
Maloney, A.2
Prodromou, C.3
Rowlands, M.G.4
Hardcastle, A.5
Boxall, K.6
Clarke, P.7
Walton, M.8
Pearl, L.9
Workman, P.10
-
83
-
-
0025024265
-
Discordant expression of heat shock protein mrnas in tissues of heat-stressed rats
-
Blake, M. J.; Gershon, D.; Fargnoli, J.; Holbrook, N. J. Discordant Expression of Heat Shock Protein Mrnas in Tissues of Heat-Stressed Rats. J. Biol. Chem. 1990, 265, 15275-15279.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 15275-15279
-
-
Blake, M.J.1
Gershon, D.2
Fargnoli, J.3
Holbrook, N.J.4
-
84
-
-
0036319568
-
Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemia
-
Lu, A.; Ran, R.; Parmentier-Batteur, S.; Nee, A.; Sharp, F. R. Geldanamycin Induces Heat Shock Proteins in Brain and Protects against Focal Cerebral Ischemia. J. Neurochem. 2002, 81, 355-364.
-
(2002)
J. Neurochem.
, vol.81
, pp. 355-364
-
-
Lu, A.1
Ran, R.2
Parmentier-Batteur, S.3
Nee, A.4
Sharp, F.R.5
-
85
-
-
0030048735
-
Regulatory differences in the stress response of hippocampal neurons and glial cells after heat shock
-
Marcuccilli, C. J.; Mathur, S. K.; Morimoto, R. I.; Miller, R. J. Regulatory Differences in the Stress Response of Hippocampal Neurons and Glial Cells After Heat Shock. J. Neurosci. 1996, 16, 478-485.
-
(1996)
J. Neurosci.
, vol.16
, pp. 478-485
-
-
Marcuccilli, C.J.1
Mathur, S.K.2
Morimoto, R.I.3
Miller, R.J.4
-
86
-
-
0028016330
-
Deficient induction of human Hsp70 heat shock gene transcription in Y79 retinoblastoma cells despite activation of heat shock factor 1
-
Mathur, S. K.; Sistonen, L.; Brown, I. R.; Murphy, S. P.; Sarge, K. D.; Morimoto, R. I. Deficient Induction of Human Hsp70 Heat Shock Gene Transcription in Y79 Retinoblastoma Cells Despite Activation of Heat Shock Factor 1. Proc. Natl. Acad. Sci. USA 1994, 91, 8695-8699.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 8695-8699
-
-
Mathur, S.K.1
Sistonen, L.2
Brown, I.R.3
Murphy, S.P.4
Sarge, K.D.5
Morimoto, R.I.6
-
87
-
-
0030791142
-
Potentiation of heat stress-induced Hsp70 expression in vivo by aspirin
-
Fawcett, T. W.; Xu, Q.; Holbrook, N. J. Potentiation of Heat Stress-Induced Hsp70 Expression in Vivo by Aspirin. Cell Stress Chap. 1997, 2, 104-109.
-
(1997)
Cell Stress Chap.
, vol.2
, pp. 104-109
-
-
Fawcett, T.W.1
Xu, Q.2
Holbrook, N.J.3
-
88
-
-
0029161913
-
Pharmacological modulation of heat shock factor I by an tiinflammatory drugs results in protection against stress-induced cellular damage
-
Lee, B. S.; Chen, J.; an gelidis, C.; Jurivich, D. A.; Morimoto, R. I. Pharmacological Modulation of Heat Shock Factor I by an tiinflammatory Drugs Results in Protection against Stress-Induced Cellular Damage. Proc. Natl. Acad. Sci. USA 1995, 92, 7207-7211.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7207-7211
-
-
Lee, B.S.1
Chen, J.2
Angelidis, C.3
Jurivich, D.A.4
Morimoto, R.I.5
-
89
-
-
0031590444
-
Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells
-
Hansen, R. K.; Oesterreich, S.; Lemieux, P.; Sarge, K. D.; Fuqua, S. A. Quercetin Inhibits Heat Shock Protein Induction But Not Heat Shock Factor DNA-Binding in Human Breast Carcinoma Cells. Biochem. Biophys. Res. Comm. 1997, 239, 851-856.
-
(1997)
Biochem. Biophys. Res. Comm.
, vol.239
, pp. 851-856
-
-
Hansen, R.K.1
Oesterreich, S.2
Lemieux, P.3
Sarge, K.D.4
Fuqua, S.A.5
-
90
-
-
0029664396
-
Modulation of prostaglandin al-induced thermotolerance by quercetin in human leukemic cells: Role of heat shock protein 70
-
Elia, G.; Amici, C.; Rossi, A.; Santoro, M. G. Modulation of Prostaglandin Al-Induced Thermotolerance by Quercetin in Human Leukemic Cells: Role of Heat Shock Protein 70. Cancer Res. 1996, 56, 210-217.
-
(1996)
Cancer Res.
, vol.56
, pp. 210-217
-
-
Elia, G.1
Amici, C.2
Rossi, A.3
Santoro, M.G.4
-
91
-
-
0029999052
-
Phase I clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
-
Ferry, D. R.; Smith, A.; Malkhandi, J.; Fyfe, D. W.; Detakats, P. G.; and erson, D.; Baker, J.; Kerr, D. J. Phase I Clinical Trial of the Flavonoid Quercetin: Pharmacokinetics and Evidence for in Vivo Tyrosine Kinase Inhibition. Clin. Cancer Res. 1996, 2, 659-668.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 659-668
-
-
Ferry, D.R.1
Smith, A.2
Malkhandi, J.3
Fyfe, D.W.4
Detakats, P.G.5
Anderson, D.6
Baker, J.7
Kerr, D.J.8
-
92
-
-
0035100834
-
Pre-clinical and clinical study of QC12, a water-soluble, pro-drug of quercetin
-
Mulholland, P. J.; Ferry, D. R.; and erson, D.; Hussain, S. A.; Young, A. M.; Cook, J. E.; Hodgkin, E.; Seymour, L. W.; Kerr, D. J. Pre-Clinical and Clinical Study of QC12, a Water-Soluble, Pro-Drug of Quercetin. Ann. Oncol. 2001, 12, 245-248.
-
(2001)
Ann. Oncol.
, vol.12
, pp. 245-248
-
-
Mulholland, P.J.1
Ferry, D.R.2
Anderson, D.3
Hussain, S.A.4
Young, A.M.5
Cook, J.E.6
Hodgkin, E.7
Seymour, L.W.8
Kerr, D.J.9
-
93
-
-
0029794271
-
Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo
-
Hutter, J. J.; Mestril, R.; Tam, E. K.; Sievers, R. E.; Dillmann, W. H.; Wolfe, C. L. Overexpression of Heat Shock Protein 72 in Transgenic Mice Decreases Infarct Size in Vivo. Circulation. 1996, 94, 1408-1411.
-
(1996)
Circulation
, vol.94
, pp. 1408-1411
-
-
Hutter, J.J.1
Mestril, R.2
Tam, E.K.3
Sievers, R.E.4
Dillmann, W.H.5
Wolfe, C.L.6
-
94
-
-
0032519663
-
Protection against myocardial dysfunction after a brief ischemic period in transgenic mice expressing inducible heat shock protein 70
-
Trost, S. U.; Omens, J. H.; Karlon, W. J.; Meyer, M.; Mestril, R.; Covell, J. W.; Dillmann, W. H. Protection against Myocardial Dysfunction after a Brief Ischemic Period in Transgenic Mice Expressing Inducible Heat Shock Protein 70. J. Clin. Invest. 1998, 101, 855-862.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 855-862
-
-
Trost, S.U.1
Omens, J.H.2
Karlon, W.J.3
Meyer, M.4
Mestril, R.5
Covell, J.W.6
Dillmann, W.H.7
-
95
-
-
0030765644
-
Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury
-
Plumier, J. C.; Krueger, A. M.; Currie, R. W.; Kontoyiannis, D.; Kollias, G.; Pagoulatos, G. N. Transgenic Mice Expressing the Human Inducible Hsp70 Have Hippocampal Neurons Resistant to Ischemic Injury. Cell Stress Chap. 1997, 2, 162-167.
-
(1997)
Cell Stress Chap.
, vol.2
, pp. 162-167
-
-
Plumier, J.C.1
Krueger, A.M.2
Currie, R.W.3
Kontoyiannis, D.4
Kollias, G.5
Pagoulatos, G.N.6
-
96
-
-
0034089551
-
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction
-
Rajdev, S.; Hara, K.; Kokubo, Y.; Mestril, R.; Dillmann, W.; Weinstein, P. R.; Sharp, F. R. Mice Overexpressing Rat Heat Shock Protein 70 Are Protected against Cerebral Infarction. Ann. Neurol. 2000, 47, 782-791.
-
(2000)
Ann. Neurol.
, vol.47
, pp. 782-791
-
-
Rajdev, S.1
Hara, K.2
Kokubo, Y.3
Mestril, R.4
Dillmann, W.5
Weinstein, P.R.6
Sharp, F.R.7
-
97
-
-
0031193541
-
Induction of heat shock proteins by tyrosine kinase inhibitors in rat cardiomyocytes and myogenic cells confers protection against simulated ischemia
-
Conde, A. G.; Lau, S. S.; Dillmann, W. H.; Mestril, R. Induction of Heat Shock Proteins by Tyrosine Kinase Inhibitors in Rat Cardiomyocytes and Myogenic Cells Confers Protection against Simulated Ischemia. J. Mol. Cell Cardiol. 1997, 29, 1927-1938.
-
(1997)
J. Mol. Cell Cardiol.
, vol.29
, pp. 1927-1938
-
-
Conde, A.G.1
Lau, S.S.2
Dillmann, W.H.3
Mestril, R.4
-
98
-
-
0028958208
-
Scrapie prions selectively modify the stress response in neuroblastoma cells
-
Tatzelt, J.; Zuo, J.; Voellmy, R.; Scott, M.; Hartl, U.; Prusiner, S. B. ; Welch, W. J. Scrapie Prions Selectively Modify the Stress Response in Neuroblastoma Cells. Proc. Natl. Acad. Sci. USA 1995, 92, 2944-2948.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 2944-2948
-
-
Tatzelt, J.1
Zuo, J.2
Voellmy, R.3
Scott, M.4
Hartl, U.5
Prusiner, S.B.6
Welch, W.J.7
-
99
-
-
0035977006
-
Geldanamycin restores a defective heat shock response in vivo
-
Winklhofer, K. F.; Reintjes, A.; Hoener, M. C.; Voellmy, R.; Tatzelt, J. Geldanamycin Restores a Defective Heat Shock Response in Vivo. J. Biol. Chem. 2001, 276, 45160-45167.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 45160-45167
-
-
Winklhofer, K.F.1
Reintjes, A.2
Hoener, M.C.3
Voellmy, R.4
Tatzelt, J.5
-
100
-
-
0035363805
-
Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of huntington's disease
-
Sittler, A.; Lurz, R.; Lueder, G.; Priller, J.; Hayer-Hartl, M. K.; Hartl, F. U.; Lehrach, H.; Wanker, E. E. Geldanamycin Activates a Heat Shock Response and Inhibits Huntingtin Aggregation in a Cell Culture Model of Huntington's Disease. Hum. Mol. Genet. 2001, 10, 1307-1315.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1307-1315
-
-
Sittler, A.1
Lurz, R.2
Lueder, G.3
Priller, J.4
Hayer-Hartl, M.K.5
Hartl, F.U.6
Lehrach, H.7
Wanker, E.E.8
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