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Volumn 217, Issue 5, 2012, Pages 521-532

CD40 Ligand: A neo-inflammatory molecule in vascular diseases

Author keywords

Athero thrombosis; Atherosclerosis; CD40; CD40 Ligand; Restenosis; Vascular cells; IIb 3, 5 1, and M 2 integrins

Indexed keywords

ALPHAIIBBETA3 INTEGRIN; ALPHAVBETA1 INTEGRIN; CD11B ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; GAMMA INTERFERON; GELATINASE A; GELATINASE B; GLYCOPROTEIN; INTERSTITIAL COLLAGENASE; STROMELYSIN; THROMBOPLASTIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG;

EID: 84858783225     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2011.03.010     Document Type: Review
Times cited : (76)

References (96)
  • 1
    • 0037143597 scopus 로고    scopus 로고
    • Platelet-derived CD40L: the switch-hitting player of cardiovascular disease
    • Andre P., Nannizzi-Alaimo L., Prasad S.K., Phillips D.R. Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation 2002, 106:896-899.
    • (2002) Circulation , vol.106 , pp. 896-899
    • Andre, P.1    Nannizzi-Alaimo, L.2    Prasad, S.K.3    Phillips, D.R.4
  • 3
    • 0344850187 scopus 로고    scopus 로고
    • Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes
    • Aukrust P., Muller F., Ueland T., Berget T., Aaser E., Brunsvig A., Solum N.O., Forfang K., Froland S.S., Gullestad L. Enhanced levels of soluble and membrane-bound CD40 ligand in patients with unstable angina. Possible reflection of T lymphocyte and platelet involvement in the pathogenesis of acute coronary syndromes. Circulation 1999, 100:614-620.
    • (1999) Circulation , vol.100 , pp. 614-620
    • Aukrust, P.1    Muller, F.2    Ueland, T.3    Berget, T.4    Aaser, E.5    Brunsvig, A.6    Solum, N.O.7    Forfang, K.8    Froland, S.S.9    Gullestad, L.10
  • 4
    • 0035129359 scopus 로고    scopus 로고
    • Inflammatory cytokines stimulate vascular smooth muscle cells locomotion and growth by enhancing alpha5beta1 integrin expression and function
    • Barillari G., Albonici L., Incerpi S., Bogetto L., Pistritto G., Volpi A., Ensoli B., Manzari V. Inflammatory cytokines stimulate vascular smooth muscle cells locomotion and growth by enhancing alpha5beta1 integrin expression and function. Atherosclerosis 2001, 154:377-385.
    • (2001) Atherosclerosis , vol.154 , pp. 377-385
    • Barillari, G.1    Albonici, L.2    Incerpi, S.3    Bogetto, L.4    Pistritto, G.5    Volpi, A.6    Ensoli, B.7    Manzari, V.8
  • 5
    • 0028171951 scopus 로고
    • Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1
    • Blystone S.D., Graham I.L., Lindberg F.P., Brown E.J. Integrin alpha v beta 3 differentially regulates adhesive and phagocytic functions of the fibronectin receptor alpha 5 beta 1. J. Cell Biol. 1994, 127:1129-1137.
    • (1994) J. Cell Biol. , vol.127 , pp. 1129-1137
    • Blystone, S.D.1    Graham, I.L.2    Lindberg, F.P.3    Brown, E.J.4
  • 7
    • 34147111879 scopus 로고    scopus 로고
    • Endothelin-1 induces functionally active CD40 protein via nuclear factor-kappaB in human vascular smooth muscle cells
    • Browatzki M., Pfeiffer C.A., Schmidt J., Kranzhofer R. Endothelin-1 induces functionally active CD40 protein via nuclear factor-kappaB in human vascular smooth muscle cells. Eur. J. Med. Res. 2007, 12:129-133.
    • (2007) Eur. J. Med. Res. , vol.12 , pp. 129-133
    • Browatzki, M.1    Pfeiffer, C.A.2    Schmidt, J.3    Kranzhofer, R.4
  • 9
    • 24944468632 scopus 로고    scopus 로고
    • Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1
    • Cascone I., Napione L., Maniero F., Serini G., Bussolino F. Stable interaction between alpha5beta1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1. J. Cell Biol. 2005, 170:993-1004.
    • (2005) J. Cell Biol. , vol.170 , pp. 993-1004
    • Cascone, I.1    Napione, L.2    Maniero, F.3    Serini, G.4    Bussolino, F.5
  • 10
    • 67349206531 scopus 로고    scopus 로고
    • Soluble CD40 ligand induces human coronary artery smooth muscle cells proliferation and migration
    • Chai H., Aghaie K., Zhou W. Soluble CD40 ligand induces human coronary artery smooth muscle cells proliferation and migration. Surgery 2009, 146:5-11.
    • (2009) Surgery , vol.146 , pp. 5-11
    • Chai, H.1    Aghaie, K.2    Zhou, W.3
  • 14
    • 0842321794 scopus 로고    scopus 로고
    • Cutting edge: T cells trigger CD40-dependent platelet activation and granular RANTES release: a novel pathway for immune response amplification
    • Danese S., de la Motte C., Reyes B.M., Sans M., Levine A.D., Fiocchi C. Cutting edge: T cells trigger CD40-dependent platelet activation and granular RANTES release: a novel pathway for immune response amplification. J. Immunol. 2004, 172:2011-2015.
    • (2004) J. Immunol. , vol.172 , pp. 2011-2015
    • Danese, S.1    de la Motte, C.2    Reyes, B.M.3    Sans, M.4    Levine, A.D.5    Fiocchi, C.6
  • 15
    • 21344454903 scopus 로고    scopus 로고
    • Platelet activation and the CD40/CD40 ligand pathway: mechanisms and implications for human disease
    • Danese S., Fiocchi C. Platelet activation and the CD40/CD40 ligand pathway: mechanisms and implications for human disease. Crit. Rev. Immunol. 2005, 25:103-121.
    • (2005) Crit. Rev. Immunol. , vol.25 , pp. 103-121
    • Danese, S.1    Fiocchi, C.2
  • 17
    • 0038719721 scopus 로고    scopus 로고
    • CD40-dependent activation of phosphatidylinositol 3-kinase/akt pathway mediates endothelial cell survival and in vitro angiogenesis
    • Deregibus M.C., Buttiglieri S., Russo S., Bussolati B., Camussi G. CD40-dependent activation of phosphatidylinositol 3-kinase/akt pathway mediates endothelial cell survival and in vitro angiogenesis. J. Biol. Chem. 2003, 278:18008-18014.
    • (2003) J. Biol. Chem. , vol.278 , pp. 18008-18014
    • Deregibus, M.C.1    Buttiglieri, S.2    Russo, S.3    Bussolati, B.4    Camussi, G.5
  • 21
    • 33746271624 scopus 로고    scopus 로고
    • Estradiol blocks the induction of CD40 and CD40L expression on endothelial cells and prevents neutrophil adhesion: an ERalpha-mediated pathway
    • Geraldes P., Gagnon S., Hadjadj S., Merhi Y., Sirois M.G., Cloutier I., Tanguay J.F. Estradiol blocks the induction of CD40 and CD40L expression on endothelial cells and prevents neutrophil adhesion: an ERalpha-mediated pathway. Cardiovasc. Res. 2006, 71:566-573.
    • (2006) Cardiovasc. Res. , vol.71 , pp. 566-573
    • Geraldes, P.1    Gagnon, S.2    Hadjadj, S.3    Merhi, Y.4    Sirois, M.G.5    Cloutier, I.6    Tanguay, J.F.7
  • 23
    • 0033792781 scopus 로고    scopus 로고
    • Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16 (Fc gammaRIII)
    • Hakkinen T., Karkola K., Yla-Herttuala S. Macrophages, smooth muscle cells, endothelial cells, and T-cells express CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16 (Fc gammaRIII). Virchows Arch. 2000, 437:396-405.
    • (2000) Virchows Arch. , vol.437 , pp. 396-405
    • Hakkinen, T.1    Karkola, K.2    Yla-Herttuala, S.3
  • 24
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson G.K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 2005, 352:1685-1695.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 25
    • 0035883087 scopus 로고    scopus 로고
    • The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40
    • Henn V., Steinbach S., Buchner K., Presek P., Kroczek R.A. The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood 2001, 98:1047-1054.
    • (2001) Blood , vol.98 , pp. 1047-1054
    • Henn, V.1    Steinbach, S.2    Buchner, K.3    Presek, P.4    Kroczek, R.A.5
  • 27
    • 74949106854 scopus 로고    scopus 로고
    • Soluble CD40 ligand impairs the function of peripheral blood angiogenic outgrowth cells and increases neointimal formation after arterial injury
    • Hristov M., Gumbel D., Lutgens E., Zernecke A., Weber C. Soluble CD40 ligand impairs the function of peripheral blood angiogenic outgrowth cells and increases neointimal formation after arterial injury. Circulation 2010, 121:315-324.
    • (2010) Circulation , vol.121 , pp. 315-324
    • Hristov, M.1    Gumbel, D.2    Lutgens, E.3    Zernecke, A.4    Weber, C.5
  • 29
    • 0030272101 scopus 로고    scopus 로고
    • Integrin activation: the link between ligand binding and signal transduction
    • Humphries M.J. Integrin activation: the link between ligand binding and signal transduction. Curr. Opin. Cell Biol. 1996, 8:632-640.
    • (1996) Curr. Opin. Cell Biol. , vol.8 , pp. 632-640
    • Humphries, M.J.1
  • 30
    • 0037877918 scopus 로고    scopus 로고
    • CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation
    • Inwald D.P., McDowall A., Peters M.J., Callard R.E., Klein N.J. CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. Circ. Res. 2003, 92:1041-1048.
    • (2003) Circ. Res. , vol.92 , pp. 1041-1048
    • Inwald, D.P.1    McDowall, A.2    Peters, M.J.3    Callard, R.E.4    Klein, N.J.5
  • 31
    • 0029073133 scopus 로고
    • CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression
    • Karmann K., Hughes C.C., Schechner J., Fanslow W.C., Pober J.S. CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:4342-4346.
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 4342-4346
    • Karmann, K.1    Hughes, C.C.2    Schechner, J.3    Fanslow, W.C.4    Pober, J.S.5
  • 32
    • 58049208322 scopus 로고    scopus 로고
    • Platelets influence vascularized organ transplants from start to finish
    • Kirk A.D., Morrell C.N., Baldwin W.M. Platelets influence vascularized organ transplants from start to finish. Am. J. Transplant. 2009, 9:14-22.
    • (2009) Am. J. Transplant. , vol.9 , pp. 14-22
    • Kirk, A.D.1    Morrell, C.N.2    Baldwin, W.M.3
  • 33
    • 0033867971 scopus 로고    scopus 로고
    • Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes
    • Kotowicz K., Dixon G.L., Klein N.J., Peters M.J., Callard R.E. Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes. Immunology 2000, 100:441-448.
    • (2000) Immunology , vol.100 , pp. 441-448
    • Kotowicz, K.1    Dixon, G.L.2    Klein, N.J.3    Peters, M.J.4    Callard, R.E.5
  • 34
    • 20444459484 scopus 로고    scopus 로고
    • Sustained elevation of serum CD40 ligand levels one month after coronary angioplasty predicts angiographic restenosis
    • L'Allier P.L., Tardif J.C., Gregoire J., Joyal M., Lesperance J., Fortier A., Guertin M.C. Sustained elevation of serum CD40 ligand levels one month after coronary angioplasty predicts angiographic restenosis. Can. J. Cardiol. 2005, 21:495-500.
    • (2005) Can. J. Cardiol. , vol.21 , pp. 495-500
    • L'Allier, P.L.1    Tardif, J.C.2    Gregoire, J.3    Joyal, M.4    Lesperance, J.5    Fortier, A.6    Guertin, M.C.7
  • 36
    • 0038301121 scopus 로고    scopus 로고
    • LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells
    • Li D., Liu L., Chen H., Sawamura T., Mehta J.L. LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. Arterioscler. Thromb. Vasc. Biol. 2003, 23:816-821.
    • (2003) Arterioscler. Thromb. Vasc. Biol. , vol.23 , pp. 816-821
    • Li, D.1    Liu, L.2    Chen, H.3    Sawamura, T.4    Mehta, J.L.5
  • 37
    • 42049091649 scopus 로고    scopus 로고
    • CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury
    • Li G., Sanders J.M., Bevard M.H., Sun Z., Chumley J.W., Galkina E.V., Ley K., Sarembock I.J. CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury. Am. J. Pathol. 2008, 172:1141-1152.
    • (2008) Am. J. Pathol. , vol.172 , pp. 1141-1152
    • Li, G.1    Sanders, J.M.2    Bevard, M.H.3    Sun, Z.4    Chumley, J.W.5    Galkina, E.V.6    Ley, K.7    Sarembock, I.J.8
  • 38
    • 0033669156 scopus 로고    scopus 로고
    • Multiple mechanisms of thrombosis complicating atherosclerotic plaques
    • VI-3-7
    • Libby P. Multiple mechanisms of thrombosis complicating atherosclerotic plaques. Clin. Cardiol. 2000, 23(Suppl. 6). VI-3-7.
    • (2000) Clin. Cardiol. , vol.23 , Issue.SUPPL. 6
    • Libby, P.1
  • 42
    • 0036140664 scopus 로고    scopus 로고
    • CD40-CD40L interactions in atherosclerosis
    • Lutgens E., Daemen M.J. CD40-CD40L interactions in atherosclerosis. Trends Cardiovasc. Med. 2002, 12:27-32.
    • (2002) Trends Cardiovasc. Med. , vol.12 , pp. 27-32
    • Lutgens, E.1    Daemen, M.J.2
  • 46
    • 0343742520 scopus 로고    scopus 로고
    • Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor
    • Mach F., Schonbeck U., Bonnefoy J.Y., Pober J.S., Libby P. Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor. Circulation 1997, 96:396-399.
    • (1997) Circulation , vol.96 , pp. 396-399
    • Mach, F.1    Schonbeck, U.2    Bonnefoy, J.Y.3    Pober, J.S.4    Libby, P.5
  • 47
    • 0345084445 scopus 로고    scopus 로고
    • CD40 signaling in vascular cells: a key role in atherosclerosis?
    • Mach F., Schonbeck U., Libby P. CD40 signaling in vascular cells: a key role in atherosclerosis?. Atherosclerosis 1998, 137(Suppl.):S89-S95.
    • (1998) Atherosclerosis , vol.137 , Issue.SUPPL.
    • Mach, F.1    Schonbeck, U.2    Libby, P.3
  • 48
    • 0031049711 scopus 로고    scopus 로고
    • Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis
    • Mach F., Schonbeck U., Sukhova G., Bourcier T., Bonnefoy J., Pober J., Libby P. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:1931-1936.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 1931-1936
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.3    Bourcier, T.4    Bonnefoy, J.5    Pober, J.6    Libby, P.7
  • 49
    • 2642608661 scopus 로고    scopus 로고
    • Reduction of atherosclerosis in mice by inhibition of CD40 signalling
    • Mach F., Schonbeck U., Sukhova G.K., Atkinson E., Libby P. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature 1998, 394:200-203.
    • (1998) Nature , vol.394 , pp. 200-203
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.K.3    Atkinson, E.4    Libby, P.5
  • 50
    • 2442635429 scopus 로고    scopus 로고
    • Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses
    • Mathur R.K., Awasthi A., Wadhone P., Ramanamurthy B., Saha B. Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses. Nat. Med. 2004, 10:540-544.
    • (2004) Nat. Med. , vol.10 , pp. 540-544
    • Mathur, R.K.1    Awasthi, A.2    Wadhone, P.3    Ramanamurthy, B.4    Saha, B.5
  • 51
    • 0037109144 scopus 로고    scopus 로고
    • Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells
    • May A.E., Kalsch T., Massberg S., Herouy Y., Schmidt R., Gawaz M. Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells. Circulation 2002, 106:2111-2117.
    • (2002) Circulation , vol.106 , pp. 2111-2117
    • May, A.E.1    Kalsch, T.2    Massberg, S.3    Herouy, Y.4    Schmidt, R.5    Gawaz, M.6
  • 52
    • 0034548824 scopus 로고    scopus 로고
    • Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo
    • Melter M., Reinders M.E., Sho M., Pal S., Geehan C., Denton M.D., Mukhopadhyay D., Briscoe D.M. Ligation of CD40 induces the expression of vascular endothelial growth factor by endothelial cells and monocytes and promotes angiogenesis in vivo. Blood 2000, 96:3801-3808.
    • (2000) Blood , vol.96 , pp. 3801-3808
    • Melter, M.1    Reinders, M.E.2    Sho, M.3    Pal, S.4    Geehan, C.5    Denton, M.D.6    Mukhopadhyay, D.7    Briscoe, D.M.8
  • 53
    • 0031907778 scopus 로고    scopus 로고
    • CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression
    • Miller D.L., Yaron R., Yellin M.J. CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression. J. Leukoc. Biol. 1998, 63:373-379.
    • (1998) J. Leukoc. Biol. , vol.63 , pp. 373-379
    • Miller, D.L.1    Yaron, R.2    Yellin, M.J.3
  • 54
    • 0345735394 scopus 로고    scopus 로고
    • CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway
    • Mukundan L., Milhorn D.M., Matta B., Suttles J. CD40-mediated activation of vascular smooth muscle cell chemokine production through a Src-initiated, MAPK-dependent pathway. Cell Signal. 2004, 16:375-384.
    • (2004) Cell Signal. , vol.16 , pp. 375-384
    • Mukundan, L.1    Milhorn, D.M.2    Matta, B.3    Suttles, J.4
  • 56
    • 36148940267 scopus 로고    scopus 로고
    • CD40-induced countercurrent conduits for tumor escape or elimination?
    • Murugaiyan G., Martin S., Saha B. CD40-induced countercurrent conduits for tumor escape or elimination?. Trends Immunol. 2007, 28:467-473.
    • (2007) Trends Immunol. , vol.28 , pp. 467-473
    • Murugaiyan, G.1    Martin, S.2    Saha, B.3
  • 57
    • 0346732383 scopus 로고    scopus 로고
    • Induction of beta-chemokine secretion by human brain microvessel endothelial cells via CD40/CD40L interactions
    • Omari K.M., Chui R., Dorovini-Zis K. Induction of beta-chemokine secretion by human brain microvessel endothelial cells via CD40/CD40L interactions. J. Neuroimmunol. 2004, 146:203-208.
    • (2004) J. Neuroimmunol. , vol.146 , pp. 203-208
    • Omari, K.M.1    Chui, R.2    Dorovini-Zis, K.3
  • 58
    • 0042328366 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the alpha 5 beta 1 integrin
    • Orecchia A., Lacal P.M., Schietroma C., Morea V., Zambruno G., Failla C.M. Vascular endothelial growth factor receptor-1 is deposited in the extracellular matrix by endothelial cells and is a ligand for the alpha 5 beta 1 integrin. J. Cell Sci. 2003, 116:3479-3489.
    • (2003) J. Cell Sci. , vol.116 , pp. 3479-3489
    • Orecchia, A.1    Lacal, P.M.2    Schietroma, C.3    Morea, V.4    Zambruno, G.5    Failla, C.M.6
  • 59
    • 38749112555 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction
    • Packard R.R., Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin. Chem. 2008, 54:24-38.
    • (2008) Clin. Chem. , vol.54 , pp. 24-38
    • Packard, R.R.1    Libby, P.2
  • 60
    • 61849157355 scopus 로고    scopus 로고
    • CD40: lord of the endothelial cell
    • Phipps R.P. CD40: lord of the endothelial cell. Blood 2008, 112:3531-3532.
    • (2008) Blood , vol.112 , pp. 3531-3532
    • Phipps, R.P.1
  • 62
    • 0142091359 scopus 로고    scopus 로고
    • Soluble CD40 ligand induces beta3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling
    • Prasad K.S., Andre P., He M., Bao M., Manganello J., Phillips D.R. Soluble CD40 ligand induces beta3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:12367-12371.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 12367-12371
    • Prasad, K.S.1    Andre, P.2    He, M.3    Bao, M.4    Manganello, J.5    Phillips, D.R.6
  • 63
    • 0032532104 scopus 로고    scopus 로고
    • Modulation of RGD sequence motifs regulates disintegrin recognition of alphaIIb beta3 and alpha5 beta1 integrin complexes. Replacement of elegantin alanine-50 with proline, N-terminal to the RGD sequence, diminishes recognition of the alpha5 beta1 complex with restoration induced by Mn2+ cation
    • Rahman S., Aitken A., Flynn G., Formstone C., Savidge G.F. Modulation of RGD sequence motifs regulates disintegrin recognition of alphaIIb beta3 and alpha5 beta1 integrin complexes. Replacement of elegantin alanine-50 with proline, N-terminal to the RGD sequence, diminishes recognition of the alpha5 beta1 complex with restoration induced by Mn2+ cation. Biochem. J. 1998, 335(Pt 2):247-257.
    • (1998) Biochem. J. , vol.335 , Issue.PART 2 , pp. 247-257
    • Rahman, S.1    Aitken, A.2    Flynn, G.3    Formstone, C.4    Savidge, G.F.5
  • 64
    • 0035793922 scopus 로고    scopus 로고
    • Absence of CD40 signaling is associated with an increase in intimal thickening after arterial injury
    • Remskar M., Li H., Chyu K.Y., Shah P.K., Cercek B. Absence of CD40 signaling is associated with an increase in intimal thickening after arterial injury. Circ. Res. 2001, 88:390-394.
    • (2001) Circ. Res. , vol.88 , pp. 390-394
    • Remskar, M.1    Li, H.2    Chyu, K.Y.3    Shah, P.K.4    Cercek, B.5
  • 65
    • 1542350044 scopus 로고    scopus 로고
    • CD40/CD40 homodimers are required for CD40-induced phosphatidylinositol 3-kinase-dependent expression of B7.2 by human B lymphocytes
    • Reyes-Moreno C., Girouard J., Lapointe R., Darveau A., Mourad W. CD40/CD40 homodimers are required for CD40-induced phosphatidylinositol 3-kinase-dependent expression of B7.2 by human B lymphocytes. J. Biol. Chem. 2004, 279:7799-7806.
    • (2004) J. Biol. Chem. , vol.279 , pp. 7799-7806
    • Reyes-Moreno, C.1    Girouard, J.2    Lapointe, R.3    Darveau, A.4    Mourad, W.5
  • 67
    • 60749115540 scopus 로고    scopus 로고
    • Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function
    • Rub A., Dey R., Jadhav M., Kamat R., Chakkaramakkil S., Majumdar S., Mukhopadhyaya R., Saha B. Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function. Nat. Immunol. 2009, 10:273-280.
    • (2009) Nat. Immunol. , vol.10 , pp. 273-280
    • Rub, A.1    Dey, R.2    Jadhav, M.3    Kamat, R.4    Chakkaramakkil, S.5    Majumdar, S.6    Mukhopadhyaya, R.7    Saha, B.8
  • 68
    • 11144275336 scopus 로고    scopus 로고
    • Induction of endothelin-1 production in endothelial cells via co-operative action between CD40 and lectin-like oxidized LDL receptor (LOX-1)
    • Sakurai K., Cominacini L., Garbin U., Fratta Pasini A., Sasaki N., Takuwa Y., Masaki T., Sawamura T. Induction of endothelin-1 production in endothelial cells via co-operative action between CD40 and lectin-like oxidized LDL receptor (LOX-1). J. Cardiovasc. Pharmacol. 2004, 44(Suppl. 1):S173-S180.
    • (2004) J. Cardiovasc. Pharmacol. , vol.44 , Issue.SUPPL. 1
    • Sakurai, K.1    Cominacini, L.2    Garbin, U.3    Fratta Pasini, A.4    Sasaki, N.5    Takuwa, Y.6    Masaki, T.7    Sawamura, T.8
  • 69
    • 33750889367 scopus 로고    scopus 로고
    • Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils
    • Sandilands G.P., McCrae J., Hill K., Perry M., Baxter D. Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils. Immunology 2006, 119:562-571.
    • (2006) Immunology , vol.119 , pp. 562-571
    • Sandilands, G.P.1    McCrae, J.2    Hill, K.3    Perry, M.4    Baxter, D.5
  • 70
    • 11144238727 scopus 로고    scopus 로고
    • CD40 ligand enhances monocyte tissue factor expression and thrombin generation via oxidative stress in patients with hypercholesterolemia
    • Sanguigni V., Ferro D., Pignatelli P., Del Ben M., Nadia T., Saliola M., Sorge R., Violi F. CD40 ligand enhances monocyte tissue factor expression and thrombin generation via oxidative stress in patients with hypercholesterolemia. J. Am. Coll. Cardiol. 2005, 45:35-42.
    • (2005) J. Am. Coll. Cardiol. , vol.45 , pp. 35-42
    • Sanguigni, V.1    Ferro, D.2    Pignatelli, P.3    Del Ben, M.4    Nadia, T.5    Saliola, M.6    Sorge, R.7    Violi, F.8
  • 71
    • 0037016008 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells
    • Schonbeck U., Gerdes N., Varo N., Reynolds R.S., Horton D.B., Bavendiek U., Robbie L., Ganz P., Kinlay S., Libby P. Oxidized low-density lipoprotein augments and 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors limit CD40 and CD40L expression in human vascular cells. Circulation 2002, 106:2888-2893.
    • (2002) Circulation , vol.106 , pp. 2888-2893
    • Schonbeck, U.1    Gerdes, N.2    Varo, N.3    Reynolds, R.S.4    Horton, D.B.5    Bavendiek, U.6    Robbie, L.7    Ganz, P.8    Kinlay, S.9    Libby, P.10
  • 72
    • 0035824895 scopus 로고    scopus 로고
    • CD40 signaling and plaque instability
    • Schonbeck U., Libby P. CD40 signaling and plaque instability. Circ. Res. 2001, 89:1092-1103.
    • (2001) Circ. Res. , vol.89 , pp. 1092-1103
    • Schonbeck, U.1    Libby, P.2
  • 73
  • 74
    • 1842406550 scopus 로고    scopus 로고
    • Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta
    • Schonbeck U., Mach F., Bonnefoy J.Y., Loppnow H., Flad H.D., Libby P. Ligation of CD40 activates interleukin 1beta-converting enzyme (caspase-1) activity in vascular smooth muscle and endothelial cells and promotes elaboration of active interleukin 1beta. J. Biol. Chem. 1997, 272:19569-19574.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19569-19574
    • Schonbeck, U.1    Mach, F.2    Bonnefoy, J.Y.3    Loppnow, H.4    Flad, H.D.5    Libby, P.6
  • 75
    • 0342872046 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?
    • Schonbeck U., Mach F., Sukhova G., Murphy C., Bonnefoy J., Fabunmi R., Libby P. Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?. J. Circ. Res. 1997, 81:448-454.
    • (1997) J. Circ. Res. , vol.81 , pp. 448-454
    • Schonbeck, U.1    Mach, F.2    Sukhova, G.3    Murphy, C.4    Bonnefoy, J.5    Fabunmi, R.6    Libby, P.7
  • 79
    • 27844599692 scopus 로고    scopus 로고
    • A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering beta1 integrin sialylation
    • Seales E.C., Shaikh F.M., Woodard-Grice A.V., Aggarwal P., McBrayer A.C., Hennessy K.M., Bellis S.L. A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering beta1 integrin sialylation. J. Biol. Chem. 2005, 280:37610-37615.
    • (2005) J. Biol. Chem. , vol.280 , pp. 37610-37615
    • Seales, E.C.1    Shaikh, F.M.2    Woodard-Grice, A.V.3    Aggarwal, P.4    McBrayer, A.C.5    Hennessy, K.M.6    Bellis, S.L.7
  • 81
    • 0033375952 scopus 로고    scopus 로고
    • CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets
    • Thienel U., Loike J., Yellin M.J. CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsets. Cell. Immunol. 1999, 198:87-95.
    • (1999) Cell. Immunol. , vol.198 , pp. 87-95
    • Thienel, U.1    Loike, J.2    Yellin, M.J.3
  • 82
    • 31344432119 scopus 로고    scopus 로고
    • Usefulness of preprocedural soluble CD40 ligand for predicting restenosis after percutaneous coronary intervention in patients with stable coronary artery disease
    • Turker S., Guneri S., Akdeniz B., Ozcan M.A., Baris N., Badak O., Kirimli O., Yuksel F. Usefulness of preprocedural soluble CD40 ligand for predicting restenosis after percutaneous coronary intervention in patients with stable coronary artery disease. Am. J. Cardiol. 2006, 97:198-202.
    • (2006) Am. J. Cardiol. , vol.97 , pp. 198-202
    • Turker, S.1    Guneri, S.2    Akdeniz, B.3    Ozcan, M.A.4    Baris, N.5    Badak, O.6    Kirimli, O.7    Yuksel, F.8
  • 85
    • 0037079695 scopus 로고    scopus 로고
    • Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1
    • Wagner A.H., Gebauer M., Pollok-Kopp B., Hecker M. Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1. Blood 2002, 99:520-525.
    • (2002) Blood , vol.99 , pp. 520-525
    • Wagner, A.H.1    Gebauer, M.2    Pollok-Kopp, B.3    Hecker, M.4
  • 86
    • 1842527883 scopus 로고    scopus 로고
    • CD154/CD40-mediated expression of CD154 in endothelial cells: consequences for endothelial cell-monocyte interaction
    • Wagner A.H., Guldenzoph B., Lienenluke B., Hecker M. CD154/CD40-mediated expression of CD154 in endothelial cells: consequences for endothelial cell-monocyte interaction. Arterioscler. Thromb. Vasc. Biol. 2004, 24:715-720.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , pp. 715-720
    • Wagner, A.H.1    Guldenzoph, B.2    Lienenluke, B.3    Hecker, M.4
  • 87
    • 33644836179 scopus 로고    scopus 로고
    • Fibronectin promotes brain capillary endothelial cell survival and proliferation through alpha5beta1 and alphavbeta3 integrins via MAP kinase signalling
    • Wang J., Milner R. Fibronectin promotes brain capillary endothelial cell survival and proliferation through alpha5beta1 and alphavbeta3 integrins via MAP kinase signalling. J. Neurochem. 2006, 96:148-159.
    • (2006) J. Neurochem. , vol.96 , pp. 148-159
    • Wang, J.1    Milner, R.2
  • 89
    • 29644438767 scopus 로고    scopus 로고
    • The expression of CD40-CD40L and activities of matrix metalloproteinases in atherosclerotic rats
    • Wu M., Li Y.G. The expression of CD40-CD40L and activities of matrix metalloproteinases in atherosclerotic rats. Mol. Cell. Biochem. 2006, 282:141-146.
    • (2006) Mol. Cell. Biochem. , vol.282 , pp. 141-146
    • Wu, M.1    Li, Y.G.2
  • 90
    • 34547844179 scopus 로고    scopus 로고
    • Activation of adventitial fibroblasts contributes to the early development of atherosclerosis: a novel hypothesis that complements the "Response-to-Injury Hypothesis" and the "Inflammation Hypothesis"
    • Xu F., Ji J., Li L., Chen R., Hu W. Activation of adventitial fibroblasts contributes to the early development of atherosclerosis: a novel hypothesis that complements the "Response-to-Injury Hypothesis" and the "Inflammation Hypothesis" Med. Hypotheses 2007, 69:908-912.
    • (2007) Med. Hypotheses , vol.69 , pp. 908-912
    • Xu, F.1    Ji, J.2    Li, L.3    Chen, R.4    Hu, W.5
  • 91
    • 78650420516 scopus 로고    scopus 로고
    • Enhanced levels of soluble CD40 ligand exacerbate platelet aggregation and thrombus formation through a CD40-dependent tumor necrosis factor receptor-associated factor-2/Rac1/p38 mitogen-activated protein kinase signaling pathway
    • Yacoub D., Hachem A., Theoret J.F., Gillis M.A., Mourad W., Merhi Y. Enhanced levels of soluble CD40 ligand exacerbate platelet aggregation and thrombus formation through a CD40-dependent tumor necrosis factor receptor-associated factor-2/Rac1/p38 mitogen-activated protein kinase signaling pathway. Arterioscler. Thromb. Vasc. Biol. 2010, 30:2424-2433.
    • (2010) Arterioscler. Thromb. Vasc. Biol. , vol.30 , pp. 2424-2433
    • Yacoub, D.1    Hachem, A.2    Theoret, J.F.3    Gillis, M.A.4    Mourad, W.5    Merhi, Y.6
  • 92
    • 33847189235 scopus 로고    scopus 로고
    • Relationship between upregulation of CD40 system and restenosis in patients after percutaneous coronary intervention
    • Yan J.C., Ding S., Liang Y., Ma G.S., Zhu J., Feng Y., Luo D. Relationship between upregulation of CD40 system and restenosis in patients after percutaneous coronary intervention. Acta Pharmacol. Sin. 2007, 28:339-343.
    • (2007) Acta Pharmacol. Sin. , vol.28 , pp. 339-343
    • Yan, J.C.1    Ding, S.2    Liang, Y.3    Ma, G.S.4    Zhu, J.5    Feng, Y.6    Luo, D.7
  • 93
    • 0028783397 scopus 로고
    • Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals
    • Yellin M.J., Brett J., Baum D., Matsushima A., Szabolcs M., Stern D., Chess L. Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signals. J. Exp. Med. 1995, 182:1857-1864.
    • (1995) J. Exp. Med. , vol.182 , pp. 1857-1864
    • Yellin, M.J.1    Brett, J.2    Baum, D.3    Matsushima, A.4    Szabolcs, M.5    Stern, D.6    Chess, L.7
  • 94
    • 0029033142 scopus 로고
    • Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation
    • Yellin M.J., Winikoff S., Fortune S.M., Baum D., Crow M.K., Lederman S., Chess L. Ligation of CD40 on fibroblasts induces CD54 (ICAM-1) and CD106 (VCAM-1) up-regulation and IL-6 production and proliferation. J. Leukoc. Biol. 1995, 58:209-216.
    • (1995) J. Leukoc. Biol. , vol.58 , pp. 209-216
    • Yellin, M.J.1    Winikoff, S.2    Fortune, S.M.3    Baum, D.4    Crow, M.K.5    Lederman, S.6    Chess, L.7


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