The effects of calpain inhibition on IkBα degradation after activation of PBMCs: Identification of the calpain cleavage sites

Neurochemical Research

Volumn 29, Issue 7, 2004, Pages 1443-1451

  Schaecher, Kurt ^a,b   Goust, Jean Michel ^a   Banik, Naren L ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

Author keywords

Calpain; Calpain inhibitor; Calpeptin; NFkB; Proteinase; T cell activation; Translocation

Indexed keywords

AMINO ACID; ANTIBODY; CALPAIN; CALPASTATIN; CALPEPTIN; CD28 ANTIBODY; CD3 ANTIBODY; GLUTAMIC ACID; GLUTAMINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEPTIDE; RECOMBINANT PROTEIN; SERINE; THREONINE; TRITON X 100; UNCLASSIFIED DRUG; CD28 ANTIGEN; CD3 ANTIGEN; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDE; I KAPPA B; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MONITORING; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; SEQUENCE ANALYSIS; TIME; UBIQUITINATION; AMINO ACID SEQUENCE; BLOOD; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; KINETICS; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; METABOLISM; MOLECULAR GENETICS; MONONUCLEAR CELL; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PHYSIOLOGY;

SUIDAE;

AMINO ACID SEQUENCE; ANTIGENS, CD28; ANTIGENS, CD3; BASE SEQUENCE; CALPAIN; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; HUMANS; I-KAPPA B PROTEINS; KINETICS; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MOLECULAR SEQUENCE DATA; NF-KAPPA B; OLIGONUCLEOTIDE PROBES;

EID: 3442884545     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NERE.0000026410.56000.dd     Document Type: Article

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