The agonist of the protease-activated receptor-1 (PAR1) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human vascular smooth muscle cells

Cellular and Molecular Life Sciences

Volumn 60, Issue 8, 2003, Pages 1716-1724

  Arisato, T ^a,b   Sarker, K P ^a,b   Kawahara, K ^a   Nakata, M ^a   Hashiguchi, T ^a   Osame, M ^a   Kitajima, I ^c   Maruyama, I ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Ca2+; HVSM cell; p44 42; PAR1; Thrombin; VEGF

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ANTITHROMBIN; CALCIMYCIN; CALCIUM ION; CALPHOSTIN C; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HEPARIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P42; PROTEIN P44; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 3; SATIGREL; THREONYLPHENYLALANYLARGINYLGLYCYLALANYLPROLINE; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE; UNCLASSIFIED DRUG; VASCULOTROPIN;

ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NORTHERN BLOTTING; PROTEIN EXPRESSION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; UPREGULATION; VASCULAR SMOOTH MUSCLE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BASE SEQUENCE; CALCIUM; CELLS, CULTURED; DNA, COMPLEMENTARY; ENDOTHELIAL GROWTH FACTORS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOKINES; MAP KINASE SIGNALING SYSTEM; MUSCLE, SMOOTH, VASCULAR; NF-KAPPA B; PEPTIDE FRAGMENTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; RNA, MESSENGER; THROMBIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0041328272     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3140-6     Document Type: Article

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