Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling

Journal of Pharmacological Sciences

Volumn 105, Issue 4, 2007, Pages 334-341

  Nakao, Takafumi ^a   Shiota, Masayuki ^a   Tatemoto, Yasuyoshi ^a   Izumi, Yasukatsu ^a   Iwao, Hiroshi ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Akt; Endothelial cell; Mammalian target of rapamycin (mTOR); p70 S6 kinase; Pravastatin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PRAVASTATIN; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE;

ANGIOGENESIS; ANIMAL CELL; AORTA; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; NONHUMAN; RAT; SIGNAL TRANSDUCTION;

EID: 37548998982     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.FP0070682     Document Type: Article

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