-
1
-
-
0036671894
-
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
F. Martinon, K. Burns, J. Tschopp, The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta, Mol. Cell 10 (2002) 417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
2
-
-
0035474227
-
The NOD: a signaling module that regulates apoptosis and host defense against pathogens
-
N. Inohara, G. Nunez, The NOD: a signaling module that regulates apoptosis and host defense against pathogens, Oncogene 20 (2001) 6473-6481.
-
(2001)
Oncogene
, vol.20
, pp. 6473-6481
-
-
Inohara, N.1
Nunez, G.2
-
3
-
-
29144452851
-
The C-type lectin-like domain superfamily
-
A.N. Zelensky, J.E. Gready, The C-type lectin-like domain superfamily, FEBS J. 272 (2005) 6179-6217.
-
(2005)
FEBS J.
, vol.272
, pp. 6179-6217
-
-
Zelensky, A.N.1
Gready, J.E.2
-
4
-
-
79956292569
-
Myeloid C-type lectin receptors in pathogen recognition and host defense
-
F. Osorio, C. Reis e Sousa, Myeloid C-type lectin receptors in pathogen recognition and host defense, Immunity 34 (2011) 651-664.
-
(2011)
Immunity
, vol.34
, pp. 651-664
-
-
Osorio, F.1
Reise Sousa, C.2
-
5
-
-
79956314622
-
Immune signaling by RIG-I-like receptors
-
Y.M. Loo, M. Gale Jr., Immune signaling by RIG-I-like receptors, Immunity 34 (2011) 680-692.
-
(2011)
Immunity
, vol.34
, pp. 680-692
-
-
Loo, Y.M.1
Gale Jr, M.2
-
6
-
-
0037077283
-
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
-
S.M. Srinivasula, J.L. Poyet, M. Razmara, P. Datta, Z. Zhang, E.S. Alnemri, The PYRIN-CARD protein ASC is an activating adaptor for caspase-1, J. Biol. Chem. 277 (2002) 21119-21122.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21119-21122
-
-
Srinivasula, S.M.1
Poyet, J.L.2
Razmara, M.3
Datta, P.4
Zhang, Z.5
Alnemri, E.S.6
-
7
-
-
79951578449
-
Inflammasomes: current understanding and open questions
-
F. Bauernfeind, A. Ablasser, E. Bartok, S. Kim, J. Schmid-Burgk, T. Cavlar, V. Hornung, Inflammasomes: current understanding and open questions, Cell. Mol. Life Sci. 68 (2011) 765-783.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 765-783
-
-
Bauernfeind, F.1
Ablasser, A.2
Bartok, E.3
Kim, S.4
Schmid-Burgk, J.5
Cavlar, T.6
Hornung, V.7
-
8
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
C.A. Dinarello, Immunological and inflammatory functions of the interleukin-1 family, Annu. Rev. Immunol. 27 (2009) 519-550.
-
(2009)
Annu. Rev. Immunol.
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
9
-
-
0031004174
-
Caspase-1 processes IFN-gammainducing factor and regulates LPS-induced IFN-gamma production
-
T. Ghayur, S. Banerjee, M. Hugunin, D. Butler, L. Herzog, A. Carter, L. Quintal, L. Sekut, R. Talanian, M. Paskind, W. Wong, R. Kamen, D. Tracey, H. Allen, Caspase-1 processes IFN-gammainducing factor and regulates LPS-induced IFN-gamma production, Nature 386 (1997) 619-623.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
Butler, D.4
Herzog, L.5
Carter, A.6
Quintal, L.7
Sekut, L.8
Talanian, R.9
Paskind, M.10
Wong, W.11
Kamen, R.12
Tracey, D.13
Allen, H.14
-
10
-
-
0026507126
-
A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes
-
N.A. Thornberry, H.G. Bull, J.R. Calaycay, K.T. Chapman, A.D. Howard, M.J. Kostura, D.K. Miller, S.M. Molineaux, J.R. Weidner, J. Aunins, A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes, Nature 356 (1992) 768-774.
-
(1992)
Nature
, vol.356
, pp. 768-774
-
-
Thornberry, N.A.1
Bull, H.G.2
Calaycay, J.R.3
Chapman, K.T.4
Howard, A.D.5
Kostura, M.J.6
Miller, D.K.7
Molineaux, S.M.8
Weidner, J.R.9
Aunins, J.10
-
12
-
-
33947717153
-
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
-
J.M. Bruey, N. Bruey-Sedano, F. Luciano, D. Zhai, R. Balpai, C. Xu, C.L. Kress, B. Bailly-Maitre, X. Li, A. Osterman, S. Matsuzawa, A.V. Terskikh, B. Faustin, J.C. Reed, Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1, Cell 129 (2007) 45-56.
-
(2007)
Cell
, vol.129
, pp. 45-56
-
-
Bruey, J.M.1
Bruey-Sedano, N.2
Luciano, F.3
Zhai, D.4
Balpai, R.5
Xu, C.6
Kress, C.L.7
Bailly-Maitre, B.8
Li, X.9
Osterman, A.10
Matsuzawa, S.11
Terskikh, A.V.12
Faustin, B.13
Reed, J.C.14
-
13
-
-
31744441475
-
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
-
E.D. Boyden, W.F. Dietrich, Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin, Nat. Genet. 38 (2006) 240-244.
-
(2006)
Nat. Genet.
, vol.38
, pp. 240-244
-
-
Boyden, E.D.1
Dietrich, W.F.2
-
14
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
V. Hornung, A. Ablasser, M. Charrel-Dennis, F. Bauernfeind, G. Horvath, D.R. Caffrey, E. Latz, K.A. Fitzgerald, AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC, Nature 458 (2009) 514-518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Latz, E.7
Fitzgerald, K.A.8
-
15
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
E.A. Miao, C.M. Puche-Aranda, M. Dors, A.E. Clark, M.W. Bader, S.I. Miller, A. Aderem, Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf, Nat. Immunol. 7 (2006) 569-575.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Puche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
Aderem, A.7
-
16
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonellainfected macrophages
-
L. Franchi, A. Amer, M. Body-Malapel, T.D. Kanneganti, N. Ozoren, R. Jagirdar, N. Inohara, P. Vandenabeele, J. Bertin, A. Coyle, E.P. Grant, G. Nunez, Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonellainfected macrophages, Nat. Immunol. 7 (2006) 576-582.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
17
-
-
0035958867
-
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
-
J.L. Poyet, S.M. Srinivasula, M. Tnani, M. Razmara, T. Fernandes-Alnemri, E.S. Alnemri, Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1, J. Biol. Chem. 276 (2001) 28309-28313.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28309-28313
-
-
Poyet, J.L.1
Srinivasula, S.M.2
Tnani, M.3
Razmara, M.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
18
-
-
69549119940
-
Molecular mechanisms involved in inflammasome activation
-
C. Bryant, K.A. Fitzgerald, Molecular mechanisms involved in inflammasome activation, Trends Cell Biol. 19 (2009) 455-464.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 455-464
-
-
Bryant, C.1
Fitzgerald, K.A.2
-
19
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
S. Mariathasan, D.S. Weiss, K. Newton, J. McBride, K. O'Rourke, M. Roose-Girma, W.P. Lee, Y. Weinrauch, D.M. Monack, V.M. Dixit, Cryopyrin activates the inflammasome in response to toxins and ATP, Nature 440 (2006) 228-232.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O'Rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
20
-
-
70449360107
-
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
-
R.R. Craven, X. Gao, I.C. Allen, D. Gris, W.J. Bubeck, E. Elvania-Tekippe, J.P. Ting, J.A. Duncan, Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells, PLoS One 4 (2009) e7446.
-
(2009)
PLoS One
, vol.4
-
-
Craven, R.R.1
Gao, X.2
Allen, I.C.3
Gris, D.4
Bubeck, W.J.5
Elvania-Tekippe, E.6
Ting, J.P.7
Duncan, J.A.8
-
21
-
-
32944462834
-
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
-
T.D. Kanneganti, N. Ozoren, M. Body-Malapel, A. Amer, J.H. Park, L. Franchi, J. Whitfield, W. Barchet, M. Colonna, P. Vandenabeele, J. Bertin, A. Coyle, E.P. Grant, S. Akira, G. Nunez, Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3, Nature 440 (2006) 233-236.
-
(2006)
Nature
, vol.440
, pp. 233-236
-
-
Kanneganti, T.D.1
Ozoren, N.2
Body-Malapel, M.3
Amer, A.4
Park, J.H.5
Franchi, L.6
Whitfield, J.7
Barchet, W.8
Colonna, M.9
Vandenabeele, P.10
Bertin, J.11
Coyle, A.12
Grant, E.P.13
Akira, S.14
Nunez, G.15
-
22
-
-
33846014297
-
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
T.D. Kanneganti, M. Body-Malapel, A. Amer, J.H. Park, J. Whitfield, L. Franchi, Z.F. Taraporewala, D. Miller, J.T. Patton, N. Inohara, G. Nunez, Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA, J. Biol. Chem. 281 (2006) 36560-36568.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
Park, J.H.4
Whitfield, J.5
Franchi, L.6
Taraporewala, Z.F.7
Miller, D.8
Patton, J.T.9
Inohara, N.10
Nunez, G.11
-
23
-
-
65549154784
-
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
-
A.G. Hise, J. Tomalka, S. Ganesan, K. Patel, B.A. Hall, G.D. Brown, K.A. Fitzgerald, An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans, Cell HostMicrobe 5 (2009) 487-497.
-
(2009)
Cell HostMicrobe
, vol.5
, pp. 487-497
-
-
Hise, A.G.1
Tomalka, J.2
Ganesan, S.3
Patel, K.4
Hall, B.A.5
Brown, G.D.6
Fitzgerald, K.A.7
-
24
-
-
70349317039
-
Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome
-
S. Joly, N. Ma, J.J. Sadler, D.R. Soll, S.L. Cassel, F.S. Sutterwala, Cutting edge: Candida albicans hyphae formation triggers activation of the Nlrp3 inflammasome, J. Immunol. 183 (2009) 3578-3581.
-
(2009)
J. Immunol.
, vol.183
, pp. 3578-3581
-
-
Joly, S.1
Ma, N.2
Sadler, J.J.3
Soll, D.R.4
Cassel, S.L.5
Sutterwala, F.S.6
-
25
-
-
67349271142
-
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
-
O. Gross, H. Poeck, M. Bscheider, C. Dostert, N. Hannesschlager, S. Endres, G. Hartmann, A. Tardivel, E. Schweighoffer, V. Tybulewicz, A. Mocsai, J. Tschopp, J. Ruland, Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence, Nature 459 (2009) 433-436.
-
(2009)
Nature
, vol.459
, pp. 433-436
-
-
Gross, O.1
Poeck, H.2
Bscheider, M.3
Dostert, C.4
Hannesschlager, N.5
Endres, S.6
Hartmann, G.7
Tardivel, A.8
Schweighoffer, E.9
Tybulewicz, V.10
Mocsai, A.11
Tschopp, J.12
Ruland, J.13
-
26
-
-
77954951536
-
Interleukin- 1, inflammasomes and the skin
-
L. Feldmeyer, S. Werner, L.E. French, H.D. Beer, Interleukin- 1, inflammasomes and the skin, Eur. J. Cell Biol. 89 (2010) 638-644.
-
(2010)
Eur. J. Cell Biol.
, vol.89
, pp. 638-644
-
-
Feldmeyer, L.1
Werner, S.2
French, L.E.3
Beer, H.D.4
-
27
-
-
47849097202
-
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
-
V. Hornung, F. Bauernfeind, A. Halle, E.O. Samstad, H. Kono, K.L. Rock, K.A. Fitzgerald, E. Latz, Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization, Nat. Immunol. 9 (2008) 847-856.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 847-856
-
-
Hornung, V.1
Bauernfeind, F.2
Halle, A.3
Samstad, E.O.4
Kono, H.5
Rock, K.L.6
Fitzgerald, K.A.7
Latz, E.8
-
28
-
-
32944468985
-
Goutassociated uric acid crystals activate the NALP3 inflammasome
-
F. Martinon, V. Petrilli, A. Mayor, A. Tardivel, J. Tschopp, Goutassociated uric acid crystals activate the NALP3 inflammasome, Nature 440 (2006) 237-241.
-
(2006)
Nature
, vol.440
, pp. 237-241
-
-
Martinon, F.1
Petrilli, V.2
Mayor, A.3
Tardivel, A.4
Tschopp, A.5
-
29
-
-
37849013277
-
Sunburned skin activates inflammasomes
-
B. Faustin, J.C. Reed, Sunburned skin activates inflammasomes, Trends Cell Biol. 18 (2008) 4-8.
-
(2008)
Trends Cell Biol.
, vol.18
, pp. 4-8
-
-
Faustin, B.1
Reed, J.C.2
-
30
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
V. Petrilli, S. Papin, C. Dostert, A. Mayor, F. Martinon, J. Tschopp, Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration, Cell Death Differ. 14 (2007) 1583-1589.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
31
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
R. Zhou, A.S. Yazdi, P. Menu, J. Tschopp, A role for mitochondria in NLRP3 inflammasome activation, Nature 469 (2011) 221-225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
32
-
-
79960542894
-
Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome
-
F. Bauernfeind, E. Bartok, A. Rieger, L. Franchi, G. Nunez, V. Hornung, Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome, J. Immunol. 187 (2011) 613-617.
-
(2011)
J. Immunol.
, vol.187
, pp. 613-617
-
-
Bauernfeind, F.1
Bartok, E.2
Rieger, A.3
Franchi, L.4
Nunez, G.5
Hornung, V.6
-
33
-
-
77749304034
-
Critical functions of priming and lysosomal damage for NLRP3 activation
-
V. Hornung, E. Latz, Critical functions of priming and lysosomal damage for NLRP3 activation, Eur. J. Immunol. 40 (2010) 620-623.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 620-623
-
-
Hornung, V.1
Latz, E.2
-
34
-
-
58149185720
-
Active caspase-1-mediated secretion of retinoic acid inducible gene-I
-
M.J. Kim, J.Y. Yoo, Active caspase-1-mediated secretion of retinoic acid inducible gene-I, J. Immunol. 181 (2008) 7324-7331.
-
(2008)
J. Immunol.
, vol.181
, pp. 7324-7331
-
-
Kim, M.J.1
Yoo, J.Y.2
-
35
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
H. Poeck, M. Bscheider, O. Gross, K. Finger, S. Roth, M. Rebsamen, N. Hannesschlager, M. Schlee, S. Rothenfusser, W. Barchet, H. Kato, S. Akira, S. Inoue, S. Endres, C. Peschel, G. Hartmann, V. Hornung, J. Ruland, Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production, Nat. Immunol. 11 (2010) 63-69.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
Hannesschlager, N.7
Schlee, M.8
Rothenfusser, S.9
Barchet, W.10
Kato, H.11
Akira, S.12
Inoue, S.13
Endres, S.14
Peschel, C.15
Hartmann, G.16
Hornung, V.17
Ruland, J.18
-
36
-
-
79956061094
-
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
-
N. Kerur, M.V. Veettil, N. Sharma-Walia, V. Bottero, S. Sadagopan, P. Otageri, B. Chandran, IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection, Cell Host Microbe 9 (2011) 363-375.
-
(2011)
Cell Host Microbe
, vol.9
, pp. 363-375
-
-
Kerur, N.1
Veettil, M.V.2
Sharma-Walia, N.3
Bottero, V.4
Sadagopan, S.5
Otageri, P.6
Chandran, B.7
-
37
-
-
84858820108
-
Novel inflammasomes and type II diabetes, intestinal inflammation and psoriasis as newly inflammasome-related diseases
-
M.C. Heymann, S.R. Hofmann, Novel inflammasomes and type II diabetes, intestinal inflammation and psoriasis as newly inflammasome-related diseases, J. Genet. Syndr. Gene Ther. S3:001 (2011) 1-8.
-
(2011)
J. Genet. Syndr. Gene Ther.
, vol.1 S3
, pp. 1-8
-
-
Heymann, M.C.1
Hofmann, S.R.2
-
38
-
-
0033515520
-
Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes
-
M.F. McDermott, I. Aksentijevich, J. Galon, E.M. McDermott, B.W. Ogunkolade, M. Centola, E. Mansfield, M. Gadina, L. Karenko, T. Pettersson, J. McCarthy, D.M. Frucht, M. Aringer, Y. Torosyan, A.M. Teppo, M. Wilson, H.M. Karaarslan, Y. Wan, I. Todd, G. Wood, R. Schlimgen, T.R. Kumarajeewa, S.M. Cooper, J.P. Vella, C.I. Amos, J. Mulley, K.A. Quane, M.G. Molloy, A. Ranki, R.J. Powell, G.A. Hitman, J.J. O'Shea, D.L. Kastner, Germline mutations in the extracellular domains of the 55 kDa TNF receptor, TNFR1, define a family of dominantly inherited autoinflammatory syndromes, Cell 97 (1999) 133-144.
-
(1999)
Cell
, vol.97
, pp. 133-144
-
-
McDermott, M.F.1
Aksentijevich, I.2
Galon, J.3
McDermott, E.M.4
Ogunkolade, B.W.5
Centola, M.6
Mansfield, E.7
Gadina, M.8
Karenko, L.9
Pettersson, T.10
McCarthy, J.11
Frucht, D.M.12
Aringer, M.13
Torosyan, Y.14
Teppo, A.M.15
Wilson, M.16
Karaarslan, H.M.17
Wan, Y.18
Todd, I.19
Wood, G.20
Schlimgen, R.21
Kumarajeewa, T.R.22
Cooper, S.M.23
Vella, J.P.24
Amos, C.I.25
Mulley, J.26
Quane, K.A.27
Molloy, M.G.28
Ranki, A.29
Powell, R.J.30
Hitman, G.A.31
O'Shea, J.J.32
Kastner, D.L.33
more..
-
39
-
-
0030745449
-
The International FMF Consortium
-
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever
-
Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The International FMF Consortium, Cell 90 (1997) 797-807.
-
(1997)
Cell
, vol.90
, pp. 797-807
-
-
-
40
-
-
77950363011
-
Autoinflammatory disease reloaded: a clinical perspective
-
D.L. Kastner, I. Aksentijevich, R. Goldbach-Mansky, Autoinflammatory disease reloaded: a clinical perspective, Cell 140 (2010) 784-790.
-
(2010)
Cell
, vol.140
, pp. 784-790
-
-
Kastner, D.L.1
Aksentijevich, I.2
Goldbach-Mansky, R.3
-
41
-
-
84867364866
-
Autoinflammatory syndromes and cellular responses to stress: pathophysiology, diagnosis and new treatment perspectives
-
S. Savic, L.J. Dickie, M. Wittmann, M.F. McDermott, Autoinflammatory syndromes and cellular responses to stress: pathophysiology, diagnosis and new treatment perspectives, Best Pract. Res. Clin. Rheumatol. 26 (2012) 505-533.
-
(2012)
Best Pract. Res. Clin. Rheumatol.
, vol.26
, pp. 505-533
-
-
Savic, S.1
Dickie, L.J.2
Wittmann, M.3
McDermott, M.F.4
-
42
-
-
33748367018
-
A proposed classification of the immunological diseases
-
D. McGonagle, M.F. McDermott, A proposed classification of the immunological diseases, PLoS Med. 3 (2006) e297.
-
(2006)
PLoS Med.
, vol.3
-
-
McGonagle, D.1
McDermott, M.F.2
-
43
-
-
71149092284
-
Autoinflammation: the prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses
-
R. Goldbach-Mansky, D.L. Kastner, Autoinflammation: the prominent role of IL-1 in monogenic autoinflammatory diseases and implications for common illnesses, J. Allergy Clin. Immunol. 124 (2009) 1141-1149.
-
(2009)
J. Allergy Clin. Immunol.
, vol.124
, pp. 1141-1149
-
-
Goldbach-Mansky, R.1
Kastner, D.L.2
-
44
-
-
66049094734
-
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes
-
H.J. Lachmann, P. Lowe, S.D. Felix, C. Rordorf, K. Leslie, S. Madhoo, H. Wittkowski, S. Bek, N. Hartmann, S. Bosset, P.N. Hawkins, T. Jung, In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes, J. Exp. Med. 206 (2009) 1029-1036.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1029-1036
-
-
Lachmann, H.J.1
Lowe, P.2
Felix, S.D.3
Rordorf, C.4
Leslie, K.5
Madhoo, S.6
Wittkowski, H.7
Bek, S.8
Hartmann, N.9
Bosset, S.10
Hawkins, P.N.11
Jung, T.12
-
45
-
-
84856367507
-
Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1
-
R. Goldbach-Mansky, Immunology in clinic review series; focus on autoinflammatory diseases: update on monogenic autoinflammatory diseases: the role of interleukin (IL)-1 and an emerging role for cytokines beyond IL-1, Clin. Exp. Immunol. 167 (2012) 391-404.
-
(2012)
Clin. Exp. Immunol.
, vol.167
, pp. 391-404
-
-
Goldbach-Mansky, R.1
-
46
-
-
2542452727
-
Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC
-
T.A. Dowds, J. Masumoto, L. Zhu, N. Inohara, G. Nunez, Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC, J. Biol. Chem. 279 (2004) 21924-21928.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21924-21928
-
-
Dowds, T.A.1
Masumoto, J.2
Zhu, L.3
Inohara, N.4
Nunez, G.5
-
48
-
-
34247252063
-
The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model
-
I. Aksentijevich, D. Putnam, E.F. Remmers, J.L. Mueller, J. Le, R.D. Kolodner, Z. Moak, M. Chuang, F. Austin, R. Goldbach-Mansky, H.M. Hoffman, D.L. Kastner, The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model, Arthritis Rheum. 56 (2007) 1273-1285.
-
(2007)
Arthritis Rheum.
, vol.56
, pp. 1273-1285
-
-
Aksentijevich, I.1
Putnam, D.2
Remmers, E.F.3
Mueller, J.L.4
Le, J.5
Kolodner, R.D.6
Moak, Z.7
Chuang, M.8
Austin, F.9
Goldbach-Mansky, R.10
Hoffman, H.M.11
Kastner, D.L.12
-
49
-
-
79951517164
-
Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France
-
L. Cuisset, I. Jeru, B. Dumont, A. Fabre, E. Cochet, B.J. Le, M. Delpech, S. Amselem, I. Touitou, Mutations in the autoinflammatory cryopyrin-associated periodic syndrome gene: epidemiological study and lessons from eight years of genetic analysis in France, Ann. Rheum. Dis. 70 (2011) 495-499.
-
(2011)
Ann. Rheum. Dis.
, vol.70
, pp. 495-499
-
-
Cuisset, L.1
Jeru, I.2
Dumont, B.3
Fabre, A.4
Cochet, E.5
Le, B.J.6
Delpech, M.7
Amselem, S.8
Touitou, I.9
-
50
-
-
0035179970
-
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
-
H.M. Hoffman, J.L. Mueller, D.H. Broide, A.A. Wanderer, R.D. Kolodner, Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome, Nat. Genet. 29 (2001) 301-305.
-
(2001)
Nat. Genet.
, vol.29
, pp. 301-305
-
-
Hoffman, H.M.1
Mueller, J.L.2
Broide, D.H.3
Wanderer, A.A.4
Kolodner, R.D.5
-
51
-
-
0036302235
-
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
-
J. Feldmann, A.M. Prieur, P. Quartier, P. Berquin, S. Certain, E. Cortis, D. Teillac-Hamel, A. Fischer, B.G. de Saint, Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes, Am. J. Hum. Genet. 71 (2002) 198-203.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 198-203
-
-
Feldmann, J.1
Prieur, A.M.2
Quartier, P.3
Berquin, P.4
Certain, S.5
Cortis, E.6
Teillac-Hamel, D.7
Fischer, A.8
de Saint, B.G.9
-
52
-
-
75749147108
-
Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap)
-
L.D. Church, S. Savic, M.F. McDermott, Long term management of patients with cryopyrin-associated periodic syndromes (CAPS): focus on rilonacept (IL-1 Trap), Biologics 2 (2008) 733-742.
-
(2008)
Biologics
, vol.2
, pp. 733-742
-
-
Church, L.D.1
Savic, S.2
McDermott, M.F.3
-
53
-
-
0036899758
-
De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases
-
I. Aksentijevich, M. Nowak, M. Mallah, J.J. Chae, W.T. Watford, S.R. Hofmann, L. Stein, R. Russo, D. Goldsmith, P. Dent, H.F. Rosenberg, F. Austin, E.F. Remmers, J.E. Balow Jr., S. Rosenzweig, H. Komarow, N.G. Shoham, G. Wood, J. Jones, N. Mangra, H. Carrero, B.S. Adams, T.L. Moore, K. Schikler, H. Hoffman, D.J. Lovell, R. Lipnick, K. Barron, J.J. O'Shea, D.L. Kastner, R. Goldbach-Mansky, De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases, Arthritis Rheum. 46 (2002) 3340-3348.
-
(2002)
Arthritis Rheum.
, vol.46
, pp. 3340-3348
-
-
Aksentijevich, I.1
Nowak, M.2
Mallah, M.3
Chae, J.J.4
Watford, W.T.5
Hofmann, S.R.6
Stein, L.7
Russo, R.8
Goldsmith, D.9
Dent, P.10
Rosenberg, H.F.11
Austin, F.12
Remmers, E.F.13
Balow Jr., J.E.14
Rosenzweig, S.15
Komarow, H.16
Shoham, N.G.17
Wood, G.18
Jones, J.19
Mangra, N.20
Carrero, H.21
Adams, B.S.22
Moore, T.L.23
Schikler, K.24
Hoffman, H.25
Lovell, D.J.26
Lipnick, R.27
Barron, K.28
O'Shea, J.J.29
Kastner, D.L.30
Goldbach-Mansky, R.31
more..
-
54
-
-
33846219617
-
Arthropathy of neonatal onset multisystem inflammatory disease (NOMID/CINCA)
-
S.C. Hill, M. Namde, A. Dwyer, A. Poznanski, S. Canna, R. Goldbach-Mansky, Arthropathy of neonatal onset multisystem inflammatory disease (NOMID/CINCA), Pediatr. Radiol. 37 (2007) 145-152.
-
(2007)
Pediatr. Radiol.
, vol.37
, pp. 145-152
-
-
Hill, S.C.1
Namde, M.2
Dwyer, A.3
Poznanski, A.4
Canna, S.5
Goldbach-Mansky, R.6
-
55
-
-
0023894493
-
A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients
-
A.M. Prieur, C. Griscelli, F. Lampert, H. Truckenbrodt, M.A. Guggenheim, D.J. Lovell, P. Pelkonnen, J. Chevrant-Breton, B.M. Ansell, A chronic, infantile, neurological, cutaneous and articular (CINCA) syndrome. A specific entity analysed in 30 patients, Scand. J. Rheumatol. Suppl. 66 (1987) 57-68.
-
(1987)
Scand. J. Rheumatol.
, Issue.SUPPL. 66
, pp. 57-68
-
-
Prieur, A.M.1
Griscelli, C.2
Lampert, F.3
Truckenbrodt, H.4
Guggenheim, M.A.5
Lovell, D.J.6
Pelkonnen, P.7
Chevrant-Breton, J.8
Ansell, B.M.9
-
56
-
-
84862272333
-
Recent advances in autoinflammatory diseases and animal models
-
S.R. Hofmann, M.C. Heymann, A. Hermsdorf, A. Roesen-Wolff, Recent advances in autoinflammatory diseases and animal models, J. Genet. Syndr. Gene Ther. S3:002 (2011) 1-7.
-
(2011)
J. Genet. Syndr. Gene Ther.
, vol.2
, Issue.S3
, pp. 1-7
-
-
Hofmann, S.R.1
Heymann, M.C.2
Hermsdorf, A.3
Roesen-Wolff, A.4
-
57
-
-
84871608014
-
Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1beta
-
H. Luksch, M.J. Romanowski, O. Chara, V. Tungler, E.R. Caffarena, M.C. Heymann, P. Lohse, I. Aksentijevich, E.F. Remmers, S. Flecks, N. Quoos, J. Gramatte, C. Petzold, S.R. Hofmann, S. Winkler, F. Pessler, T. Kallinich, G. Ganser, A. Nimtz-Talaska, U. Baumann, V. Runde, B. Grimbacher, J. Birmelin,M. Gahr, J. Roesler, A. Rosen-Wolff, Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1beta, Hum. Mutat. 34 (2013) 122-131.
-
(2013)
Hum. Mutat.
, vol.34
, pp. 122-131
-
-
Luksch, H.1
Romanowski, M.J.2
Chara, O.3
Tungler, V.4
Caffarena, E.R.5
Heymann, M.C.6
Lohse, P.7
Aksentijevich, I.8
Remmers, E.F.9
Flecks, S.10
Quoos, N.11
Gramatte, J.12
Petzold, C.13
Hofmann, S.R.14
Winkler, S.15
Pessler, F.16
Kallinich, T.17
Ganser, G.18
Nimtz-Talaska, A.19
Baumann, U.20
Runde, V.21
Grimbacher, B.22
Birmelin, J.23
Gahr, M.24
Roesler, J.25
Rosen-Wolff, A.26
more..
-
58
-
-
80053894653
-
Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor kappaB signaling
-
K. Kersse, M. Lamkanfi, M.J. Bertrand, B.T. Vanden, P. Vandenabeele, Interaction patches of procaspase-1 caspase recruitment domains (CARDs) are differently involved in procaspase-1 activation and receptor-interacting protein 2 (RIP2)-dependent nuclear factor kappaB signaling, J. Biol. Chem. 286 (2011) 35874-35882.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 35874-35882
-
-
Kersse, K.1
Lamkanfi, M.2
Bertrand, M.J.3
Vanden, B.T.4
Vandenabeele, P.5
-
59
-
-
2642517305
-
Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity
-
M. Lamkanfi, M. Kalai, X. Saelens, W. Declercq, P. Vandenabeele, Caspase-1 activates nuclear factor of the kappa-enhancer in B cells independently of its enzymatic activity, J. Biol. Chem. 279 (2004) 24785-24793.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24785-24793
-
-
Lamkanfi, M.1
Kalai, M.2
Saelens, X.3
Declercq, W.4
Vandenabeele, P.5
-
60
-
-
35349011610
-
The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers
-
S.M. Woerner, M. Kloor, Y. Schwitalle, H. Youmans, M.K. Doeberitz, J. Gebert, S. Dihlmann, The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers, Genes Chromosomes Cancer 46 (2007) 1080-1089.
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 1080-1089
-
-
Woerner, S.M.1
Kloor, M.2
Schwitalle, Y.3
Youmans, H.4
Doeberitz, M.K.5
Gebert, J.6
Dihlmann, S.7
-
61
-
-
84859007742
-
-
Overexpression of the DNA sensor proteins, absent in melanoma 2 and interferon-inducible 16, contributes to tumorigenesis of oral squamous cell carcinoma with p53 inactivation
-
Y. Kondo, K. Nagai, S. Nakahata, Y. Saito, T. Ichikawa, A. Suekane, T. Taki, R. Iwakawa, M. Enari, M. Taniwaki, J. Yokota, S. Sakoda, K. Morishita, Overexpression of the DNA sensor proteins, absent in melanoma 2 and interferon-inducible 16, contributes to tumorigenesis of oral squamous cell carcinoma with p53 inactivation, Cancer Sci. 103 (2012) 782-790.
-
(2012)
Cancer Sci.
, vol.103
, pp. 782-790
-
-
Kondo, Y.1
Nagai, K.2
Nakahata, S.3
Saito, Y.4
Ichikawa, T.5
Suekane, A.6
Taki, T.7
Iwakawa, R.8
Enari, M.9
Taniwaki, M.10
Yokota, J.11
Sakoda, S.12
Morishita, K.13
-
62
-
-
77958088176
-
Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs
-
A. Alkhateeb, F. Qarqaz, Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs, Arch. Dermatol. Res. 302 (2010) 631-634.
-
(2010)
Arch. Dermatol. Res.
, vol.302
, pp. 631-634
-
-
Alkhateeb, A.1
Qarqaz, F.2
-
63
-
-
34447304633
-
Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population
-
Y. Jin, S.A. Birlea, P.R. Fain, R.A. Spritz, Genetic variations in NALP1 are associated with generalized vitiligo in a Romanian population, J. Invest. Dermatol. 127 (2007) 2558-2562.
-
(2007)
J. Invest. Dermatol.
, vol.127
, pp. 2558-2562
-
-
Jin, Y.1
Birlea, S.A.2
Fain, P.R.3
Spritz, R.A.4
-
64
-
-
79952361297
-
The missense variation Q705K in CIAS1/NALP3/NLRP3 gene and an NLRP1 haplotype are associated with celiac disease
-
A. Pontillo, A. Vendramin, E. Catamo, A. Fabris, S. Crovella, The missense variation Q705K in CIAS1/NALP3/NLRP3 gene and an NLRP1 haplotype are associated with celiac disease, Am. J. Gastroenterol. 106 (2011) 539-544.
-
(2011)
Am. J. Gastroenterol.
, vol.106
, pp. 539-544
-
-
Pontillo, A.1
Vendramin, A.2
Catamo, E.3
Fabris, A.4
Crovella, S.5
-
65
-
-
67650354198
-
Recurrent febrile syndromes: what a rheumatologist needs to know
-
H.M. Hoffman, A. Simon, Recurrent febrile syndromes: what a rheumatologist needs to know, Nat. Rev. Rheumatol. 5 (2009) 249-256.
-
(2009)
Nat. Rev. Rheumatol.
, vol.5
, pp. 249-256
-
-
Hoffman, H.M.1
Simon, A.2
-
66
-
-
84856394478
-
Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes
-
V.U. Ozkurede, L. Franchi, Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes, Clin. Exp. Immunol. 167 (2012) 382-390.
-
(2012)
Clin. Exp. Immunol.
, vol.167
, pp. 382-390
-
-
Ozkurede, V.U.1
Franchi, L.2
-
67
-
-
35549004467
-
Familial Mediterranean fever: clinical, molecular and management advancements
-
M. Lidar, A. Livneh, Familial Mediterranean fever: clinical, molecular and management advancements, Neth. J. Med. 65 (2007) 318-324.
-
(2007)
Neth. J. Med.
, vol.65
, pp. 318-324
-
-
Lidar, M.1
Livneh, A.2
-
68
-
-
84866502550
-
The effect of colchicine on pyrin and pyrin interacting proteins
-
E.Z. Taskiran, A. Cetinkaya, B. Balci-Peynircioglu, Y.Z. Akkaya, E. Yilmaz, The effect of colchicine on pyrin and pyrin interacting proteins, J. Cell. Biochem. 113 (2012) 3536-3546.
-
(2012)
J. Cell. Biochem.
, vol.113
, pp. 3536-3546
-
-
Taskiran, E.Z.1
Cetinkaya, A.2
Balci-Peynircioglu, B.3
Akkaya, Y.Z.4
Yilmaz, E.5
-
69
-
-
0035914452
-
Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis
-
N. Richards, P. Schaner, A. Diaz, J. Stuckey, E. Shelden, A. Wadhwa, D.L. Gumucio, Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis, J. Biol. Chem. 276 (2001) 39320-39329.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39320-39329
-
-
Richards, N.1
Schaner, P.2
Diaz, A.3
Stuckey, J.4
Shelden, E.5
Wadhwa, A.6
Gumucio, D.L.7
-
70
-
-
0037349294
-
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
-
J.J. Chae, H.D. Komarow, J. Cheng, G. Wood, N. Raben, P.P. Liu, D.L. Kastner, Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis, Mol. Cell 11 (2003) 591-604.
-
(2003)
Mol. Cell
, vol.11
, pp. 591-604
-
-
Chae, J.J.1
Komarow, H.D.2
Cheng, J.3
Wood, G.4
Raben, N.5
Liu, P.P.6
Kastner, D.L.7
-
71
-
-
34547138176
-
The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing
-
S. Papin, S. Cuenin, L. Agostini, F. Martinon, S. Werner, H.D. Beer, C. Grutter, M. Grutter, J. Tschopp, The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing, Cell Death Differ. 14 (2007) 1457-1466.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1457-1466
-
-
Papin, S.1
Cuenin, S.2
Agostini, L.3
Martinon, F.4
Werner, S.5
Beer, H.D.6
Grutter, C.7
Grutter, M.8
Tschopp, J.9
-
72
-
-
0037436868
-
Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product
-
T.A. Dowds, J. Masumoto, F.F. Chen, Y. Ogura, N. Inohara, G. Nunez, Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product, Biochem. Biophys. Res. Commun. 302 (2003) 575-580.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.302
, pp. 575-580
-
-
Dowds, T.A.1
Masumoto, J.2
Chen, F.F.3
Ogura, Y.4
Inohara, N.5
Nunez, G.6
-
73
-
-
84861344389
-
Rare hereditary autoinflammatory disorders: towards an understanding of critical in vivo inflammatory pathways
-
N. Kanazawa, Rare hereditary autoinflammatory disorders: towards an understanding of critical in vivo inflammatory pathways, J. Dermatol. Sci. 66 (2012) 183-189.
-
(2012)
J. Dermatol. Sci.
, vol.66
, pp. 183-189
-
-
Kanazawa, N.1
-
74
-
-
33745631232
-
The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production
-
J.J. Chae, G. Wood, S.L. Masters, K. Richard, G. Park, B.J. Smith, D.L. Kastner, The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production, Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 9982-9987.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 9982-9987
-
-
Chae, J.J.1
Wood, G.2
Masters, S.L.3
Richard, K.4
Park, G.5
Smith, B.J.6
Kastner, D.L.7
-
75
-
-
35348934890
-
Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants
-
J.W. Yu, T. Fernandes-Alnemri, P. Datta, J. Wu, C. Juliana, L. Solorzano, M. McCormick, Z. Zhang, E.S. Alnemri, Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants, Mol. Cell 28 (2007) 214-227.
-
(2007)
Mol. Cell
, vol.28
, pp. 214-227
-
-
Yu, J.W.1
Fernandes-Alnemri, T.2
Datta, P.3
Wu, J.4
Juliana, C.5
Solorzano, L.6
McCormick, M.7
Zhang, Z.8
Alnemri, E.S.9
-
76
-
-
34548768341
-
Pyrin levels in human monocytes and monocytederived macrophages regulate IL-1beta processing and release
-
S. Seshadri, M.D. Duncan, J.M. Hart, M.A. Gavrilin, M.D. Wewers, Pyrin levels in human monocytes and monocytederived macrophages regulate IL-1beta processing and release, J. Immunol. 179 (2007) 1274-1281.
-
(2007)
J. Immunol.
, vol.179
, pp. 1274-1281
-
-
Seshadri, S.1
Duncan, M.D.2
Hart, J.M.3
Gavrilin, M.A.4
Wewers, M.D.5
-
78
-
-
79956299492
-
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin- 1beta activation and severe autoinflammation in mice
-
J.J. Chae, Y.H. Cho, G.S. Lee, J. Cheng, P.P. Liu, L. Feigenbaum, S.I. Katz, D.L. Kastner, Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin- 1beta activation and severe autoinflammation in mice, Immunity 34 (2011) 755-768.
-
(2011)
Immunity
, vol.34
, pp. 755-768
-
-
Chae, J.J.1
Cho, Y.H.2
Lee, G.S.3
Cheng, J.4
Liu, P.P.5
Feigenbaum, L.6
Katz, S.I.7
Kastner, D.L.8
-
79
-
-
0030804743
-
A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome
-
N.M. Lindor, T.M. Arsenault, H. Solomon, C.E. Seidman, M.T. McEvoy, A new autosomal dominant disorder of pyogenic sterile arthritis, pyoderma gangrenosum, and acne: PAPA syndrome, Mayo Clin. Proc. 72 (1997) 611-615.
-
(1997)
Mayo Clin. Proc.
, vol.72
, pp. 611-615
-
-
Lindor, N.M.1
Arsenault, T.M.2
Solomon, H.3
Seidman, C.E.4
McEvoy, M.T.5
-
80
-
-
78650006414
-
Clinical, molecular, and genetic characteristics of PAPA syndrome: a review
-
E.J. Smith, F. Allantaz, L. Bennett, D. Zhang, X. Gao, G. Wood, D.L. Kastner, M. Punaro, I. Aksentijevich, V. Pascual, C.A. Wise, Clinical, molecular, and genetic characteristics of PAPA syndrome: a review, Curr. Genomics 11 (2010) 519-527.
-
(2010)
Curr. Genomics
, vol.11
, pp. 519-527
-
-
Smith, E.J.1
Allantaz, F.2
Bennett, L.3
Zhang, D.4
Gao, X.5
Wood, G.6
Kastner, D.L.7
Punaro, M.8
Aksentijevich, I.9
Pascual, V.10
Wise, C.A.11
-
81
-
-
0037091012
-
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
-
C.A. Wise, J.D. Gillum, C.E. Seidman, N.M. Lindor, R. Veile, S. Bashiardes, M. Lovett, Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder, Hum. Mol. Genet. 11 (2002) 961-969.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 961-969
-
-
Wise, C.A.1
Gillum, J.D.2
Seidman, C.E.3
Lindor, N.M.4
Veile, R.5
Bashiardes, S.6
Lovett, M.7
-
82
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
N.G. Shoham, M. Centola, E. Mansfield, K.M. Hull, G. Wood, C.A. Wise, D.L. Kastner, Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway, Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 13501-13506.
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
Centola, M.2
Mansfield, E.3
Hull, K.M.4
Wood, G.5
Wise, C.A.6
Kastner, D.L.7
-
83
-
-
67650222428
-
Pyrin modulates the intracellular distribution of PSTPIP1
-
A.L. Waite, P. Schaner, N. Richards, B. Balci-Peynircioglu, S.L. Masters, S.D. Brydges, M. Fox, A. Hong, E. Yilmaz, D.L. Kastner, E.L. Reinherz, D.L. Gumucio, Pyrin modulates the intracellular distribution of PSTPIP1, PLoS One 4 (2009) e6147.
-
(2009)
PLoS One
, vol.4
-
-
Waite, A.L.1
Schaner, P.2
Richards, N.3
Balci-Peynircioglu, B.4
Masters, S.L.5
Brydges, S.D.6
Fox, M.7
Hong, A.8
Yilmaz, E.9
Kastner, D.L.10
Reinherz, E.L.11
Gumucio, D.L.12
-
84
-
-
60549111042
-
Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin
-
A.L. Waite, P. Schaner, C. Hu, N. Richards, B. Balci-Peynircioglu, A. Hong, M. Fox, D.L. Gumucio, Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin, Exp. Biol. Med. (Maywood) 234 (2009) 40-52.
-
(2009)
Exp. Biol. Med. (Maywood)
, vol.234
, pp. 40-52
-
-
Waite, A.L.1
Schaner, P.2
Hu, C.3
Richards, N.4
Balci-Peynircioglu, B.5
Hong, A.6
Fox, M.7
Gumucio, D.L.8
-
85
-
-
81255136243
-
Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum
-
A.B. Nesterovitch, M.D. Hoffman, M. Simon, P.A. Petukhov, M.D. Tharp, T.T. Glant, Mutations in the PSTPIP1 gene and aberrant splicing variants in patients with pyoderma gangrenosum, Clin. Exp. Dermatol. 36 (2011) 889-895.
-
(2011)
Clin. Exp. Dermatol.
, vol.36
, pp. 889-895
-
-
Nesterovitch, A.B.1
Hoffman, M.D.2
Simon, M.3
Petukhov, P.A.4
Tharp, M.D.5
Glant, T.T.6
-
86
-
-
33746747096
-
MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals
-
C.J. Chen, Y. Shi, A. Hearn, K. Fitzgerald, D. Golenbock, G. Reed, S. Akira, K.L. Rock, MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals, J. Clin. Invest. 116 (2006) 2262-2271.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2262-2271
-
-
Chen, C.J.1
Shi, Y.2
Hearn, A.3
Fitzgerald, K.4
Golenbock, D.5
Reed, G.6
Akira, S.7
Rock, K.L.8
-
87
-
-
34047174085
-
A pilot study of IL-1 inhibition by anakinra in acute gout
-
A. So, S.T. De, S. Revaz, J. Tschopp, A pilot study of IL-1 inhibition by anakinra in acute gout, Arthritis Res. Ther. 9 (2007) R28.
-
(2007)
Arthritis Res. Ther.
, vol.9
-
-
So, A.1
De, S.T.2
Revaz, S.3
Tschopp, J.4
-
88
-
-
53149123653
-
Inflammasomes and rheumatic diseases: evolving concepts
-
P.I. Sidiropoulos, G. Goulielmos, G.K. Voloudakis, E. Petraki, D.T. Boumpas, Inflammasomes and rheumatic diseases: evolving concepts, Ann. Rheum. Dis. 67 (2008) 1382-1389.
-
(2008)
Ann. Rheum. Dis.
, vol.67
, pp. 1382-1389
-
-
Sidiropoulos, P.I.1
Goulielmos, G.2
Voloudakis, G.K.3
Petraki, E.4
Boumpas, D.T.5
-
89
-
-
0022445268
-
Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans
-
K. Bendtzen, T. Mandrup-Poulsen, J. Nerup, J.H. Nielsen, C.A. Dinarello, M. Svenson, Cytotoxicity of human pI 7 interleukin-1 for pancreatic islets of Langerhans, Science 232 (1986) 1545-1547.
-
(1986)
Science
, vol.232
, pp. 1545-1547
-
-
Bendtzen, K.1
Mandrup-Poulsen, T.2
Nerup, J.3
Nielsen, J.H.4
Dinarello, C.A.5
Svenson, M.6
-
90
-
-
0345700727
-
Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
-
J. Spranger, A. Kroke, M. Mohlig, K. Hoffmann, M.M. Bergmann, M. Ristow, H. Boeing, A.F. Pfeiffer, Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study, Diabetes 52 (2003) 812-817.
-
(2003)
Diabetes
, vol.52
, pp. 812-817
-
-
Spranger, J.1
Kroke, A.2
Mohlig, M.3
Hoffmann, K.4
Bergmann, M.M.5
Ristow, M.6
Boeing, H.7
Pfeiffer, A.F.8
-
91
-
-
34247170807
-
Interleukin- 1-receptor antagonist in type 2 diabetes mellitus
-
C.M. Larsen, M. Faulenbach, A. Vaag, A. Volund, J.A. Ehses, B. Seifert, T. Mandrup-Poulsen, M.Y. Donath, Interleukin- 1-receptor antagonist in type 2 diabetes mellitus, N. Engl. J. Med. 356 (2007) 1517-1526.
-
(2007)
N. Engl. J. Med.
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
Volund, A.4
Ehses, J.A.5
Seifert, B.6
Mandrup-Poulsen, T.7
Donath, M.Y.8
-
92
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
P. Duewell, H. Kono, K.J. Rayner, C.M. Sirois, G. Vladimer, F.G. Bauernfeind, G.S. Abela, L. Franchi, G. Nunez, M. Schnurr, T. Espevik, E. Lien, K.A. Fitzgerald, K.L. Rock, K.J. Moore, S.D. Wright, V. Hornung, E. Latz, NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals, Nature 464 (2010) 1357-1361.
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
Kono, H.2
Rayner, K.J.3
Sirois, C.M.4
Vladimer, G.5
Bauernfeind, F.G.6
Abela, G.S.7
Franchi, L.8
Nunez, G.9
Schnurr, M.10
Espevik, T.11
Lien, E.12
Fitzgerald, K.A.13
Rock, K.L.14
Moore, K.J.15
Wright, S.D.16
Hornung, V.17
Latz, E.18
-
93
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
H. Wen, D. Gris, Y. Lei, S. Jha, L. Zhang, M.T. Huang, W.J. Brickey, J.P. Ting, Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling, Nat. Immunol. 12 (2011) 408-415.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
Jha, S.4
Zhang, L.5
Huang, M.T.6
Brickey, W.J.7
Ting, J.P.8
-
94
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
B. Vandanmagsar, Y.H. Youm, A. Ravussin, J.E. Galgani, K. Stadler, R.L. Mynatt, E. Ravussin, J.M. Stephens, V.D. Dixit, The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance, Nat. Med. 17 (2011) 179-188.
-
(2011)
Nat. Med.
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
Galgani, J.E.4
Stadler, K.5
Mynatt, R.L.6
Ravussin, E.7
Stephens, J.M.8
Dixit, V.D.9
-
95
-
-
77956958947
-
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes
-
S.L. Masters, A. Dunne, S.L. Subramanian, R.L. Hull, G.M. Tannahill, F.A. Sharp, C. Becker, L. Franchi, E. Yoshihara, Z. Chen, N. Mullooly, L.A. Mielke, J. Harris, R.C. Coll, K.H. Mills, K.H. Mok, P. Newsholme, G. Nunez, J. Yodoi, S.E. Kahn, E.C. Lavelle, L.A. O'Neill, Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes, Nat. Immunol. 11 (2010) 897-904.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 897-904
-
-
Masters, S.L.1
Dunne, A.2
Subramanian, S.L.3
Hull, R.L.4
Tannahill, G.M.5
Sharp, F.A.6
Becker, C.7
Franchi, L.8
Yoshihara, E.9
Chen, Z.10
Mullooly, N.11
Mielke, L.A.12
Harris, J.13
Coll, R.C.14
Mills, K.H.15
Mok, K.H.16
Newsholme, P.17
Nunez, G.18
Yodoi, J.19
Kahn, S.E.20
Lavelle, E.C.21
O'Neill, L.A.22
more..
-
96
-
-
0024213009
-
Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes
-
A. Clark, C.A. Wells, I.D. Buley, J.K. Cruickshank, R.I. Vanhegan, D.R. Matthews, G.J. Cooper, R.R. Holman, R.C. Turner, Islet amyloid, increased A-cells, reduced B-cells and exocrine fibrosis: quantitative changes in the pancreas in type 2 diabetes, Diabetes Res. 9 (1988) 151-159.
-
(1988)
Diabetes Res.
, vol.9
, pp. 151-159
-
-
Clark, A.1
Wells, C.A.2
Buley, I.D.3
Cruickshank, J.K.4
Vanhegan, R.I.5
Matthews, D.R.6
Cooper, G.J.7
Holman, R.R.8
Turner, R.C.9
-
97
-
-
79952969400
-
Gevokizumab, an anti-IL-1beta mAb for the potential treatment of type 1 and 2 diabetes, rheumatoid arthritis and cardiovascular disease
-
J. Geiler, M.F. McDermott, Gevokizumab, an anti-IL-1beta mAb for the potential treatment of type 1 and 2 diabetes, rheumatoid arthritis and cardiovascular disease, Curr. Opin. Mol. Ther. 12 (2010) 755-769.
-
(2010)
Curr. Opin. Mol. Ther.
, vol.12
, pp. 755-769
-
-
Geiler, J.1
McDermott, M.F.2
-
98
-
-
80055084799
-
Preliminary studies related to anti-interleukin-1beta therapy in children with newly diagnosed type 1 diabetes
-
K.M. Sumpter, S. Adhikari, E.K. Grishman, P.C. White, Preliminary studies related to anti-interleukin-1beta therapy in children with newly diagnosed type 1 diabetes, Pediatr. Diabetes 12 (2011) 656-667.
-
(2011)
Pediatr. Diabetes
, vol.12
, pp. 656-667
-
-
Sumpter, K.M.1
Adhikari, S.2
Grishman, E.K.3
White, P.C.4
-
99
-
-
66949115474
-
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity
-
S.D. Brydges, J.L. Mueller, M.D. McGeough, C.A. Pena, A. Misaghi, C. Gandhi, C.D. Putnam, D.L. Boyle, G.S. Firestein, A.A. Horner, P. Soroosh, W.T. Watford, J.J. O'Shea, D.L. Kastner, H.M. Hoffman, Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity, Immunity 30 (2009) 875-887.
-
(2009)
Immunity
, vol.30
, pp. 875-887
-
-
Brydges, S.D.1
Mueller, J.L.2
McGeough, M.D.3
Pena, C.A.4
Misaghi, A.5
Gandhi, C.6
Putnam, C.D.7
Boyle, D.L.8
Firestein, G.S.9
Horner, A.A.10
Soroosh, P.11
Watford, W.T.12
O'Shea, J.J.13
Kastner, D.L.14
Hoffman, H.M.15
-
100
-
-
66949175347
-
A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
-
G. Meng, F. Zhang, I. Fuss, A. Kitani, W. Strober, A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses, Immunity 30 (2009) 860-874.
-
(2009)
Immunity
, vol.30
, pp. 860-874
-
-
Meng, G.1
Zhang, F.2
Fuss, I.3
Kitani, A.4
Strober, W.5
-
101
-
-
84860475314
-
Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice
-
S.L. Bonar, S.D. Brydges, J.L. Mueller, M.D. McGeough, C. Pena, D. Chen, S.K. Grimston, C.L. Hickman-Brecks, S. Ravindran, A. McAlinden, D.V. Novack, D.L. Kastner, R. Civitelli, H.M. Hoffman, G. Mbalaviele, Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice, PLoS One 7 (2012) e35979.
-
(2012)
PLoS One
, vol.7
-
-
Bonar, S.L.1
Brydges, S.D.2
Mueller, J.L.3
McGeough, M.D.4
Pena, C.5
Chen, D.6
Grimston, S.K.7
Hickman-Brecks, C.L.8
Ravindran, S.9
McAlinden, A.10
Novack, D.V.11
Kastner, D.L.12
Civitelli, R.13
Hoffman, H.M.14
Mbalaviele, G.15
-
102
-
-
0028984948
-
Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
-
P. Li, H. Allen, S. Banerjee, S. Franklin, L. Herzog, C. Johnston, J. McDowell, M. Paskind, L. Rodman, J. Salfeld, Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock, Cell 80 (1995) 401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
103
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
N. Kayagaki, S. Warming, M. Lamkanfi, W.L. Vande, S. Louie, J. Dong, K. Newton, Y. Qu, J. Liu, S. Heldens, J. Zhang, W.P. Lee, M. Roose-Girma, V.M. Dixit, Non-canonical inflammasome activation targets caspase-11, Nature 479 (2011) 117-121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande, W.L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
Zhang, J.11
Lee, W.P.12
Roose-Girma, M.13
Dixit, V.M.14
|