Resveratrol down-regulates interferon-γ-inducible inflammatory genes in macrophages: Molecular mechanism via decreased STAT-1 activation

Journal of Nutritional Biochemistry

Volumn 22, Issue 10, 2011, Pages 902-909

  Chung, Eun Yong ^a   Kim, Byung Hak ^a   Hong, Jin Tae ^a   Lee, Chong Kil ^a   Ahn, Byeongwoo ^a   Nam, Sang Yoon ^a   Han, Sang Bae ^a   Kim, Youngsoo ^a  

^a Chungbuk National University   (South Korea)

Author keywords

Inflammatory macrophages; Interferon ; Phytoalexin; Resveratrol; STAT 1

Indexed keywords

CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INDUCIBLE NITRIC OXIDE SYNTHASE; INOSINATE DEHYDROGENASE; JANUS KINASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PHYTOALEXIN; RESVERATROL; SERINE; STAT1 PROTEIN; TOLL LIKE RECEPTOR 4; TYROSINE;

ANIMAL CELL; ARTICLE; BONE MARROW; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; INFLAMMATION; MACROPHAGE; MALE; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; CHEMOKINE CXCL10; DOWN-REGULATION; HUMANS; INTERFERON-GAMMA; JANUS KINASE 2; MACROPHAGES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHORYLATION; RNA, MESSENGER; STAT1 TRANSCRIPTION FACTOR; STILBENES; TRANSCRIPTION, GENETIC;

CUCURBITA; MUS; VITACEAE;

EID: 80053091840     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2010.07.012     Document Type: Article

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