-
1
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
DOI 10.1016/S0140-6736(00)04046-0
-
Balkwill F, Mantovani A (2001) Inflammation and cancer: back to Virchow? Lancet 357:539-545 (Pubitemid 32173595)
-
(2001)
Lancet
, vol.357
, Issue.9255
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
2
-
-
0036187615
-
The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
-
DOI 10.1002/path.1027
-
Bingle L, Brown NJ, Lewis CE (2002) The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol 196:254-265 (Pubitemid 34189413)
-
(2002)
Journal of Pathology
, vol.196
, Issue.3
, pp. 254-265
-
-
Bingle, L.1
Brown, N.J.2
Lewis, C.E.3
-
3
-
-
0040034149
-
Evidence of hypoxic areas within the arterial wall in vivo
-
Bjornheden T, Levin M, Evaldsson M, Wiklund O (1999) Evidence of hypoxic areas within the arterial wall in vivo. Arterioscler Thromb Vasc Biol 19:870-876 (Pubitemid 29177331)
-
(1999)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.19
, Issue.4
, pp. 870-876
-
-
Bjornheden, T.1
Levin, M.2
Evaldsson, M.3
Wiklund, O.4
-
6
-
-
0032053823
-
The unique physiology of solid tumors: Opportunities (and problems) for cancer therapy
-
Brown JM, Giaccia AJ (1998) The unique physiology of solid tumors: opportunities (and problems) for cancer therapy. Cancer Res 58:1408-1416 (Pubitemid 28193601)
-
(1998)
Cancer Research
, vol.58
, Issue.7
, pp. 1408-1416
-
-
Brown, J.M.1
Giaccia, A.J.2
-
7
-
-
0036007293
-
Expression of HIF-Iα by human macrophages: Implications for the use of macrophages in hypoxia-regulated cancer gene therapy
-
DOI 10.1002/path.1029
-
Burke B, Tang N, Corke KP, Tazzyman D, Ameri K, Wells M, Lewis CE (2002) Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxiaregulated cancer gene therapy. J Pathol 196:204-212 (Pubitemid 34110902)
-
(2002)
Journal of Pathology
, vol.196
, Issue.2
, pp. 204-212
-
-
Burke, B.1
Tang, N.2
Corke, K.P.3
Tazzyman, D.4
Ameri, K.5
Wells, M.6
Lewis, C.E.7
-
8
-
-
0027935309
-
Leukocyte-endothelial adhesion molecules
-
Carlos TM, Harlan JM (1994) Leukocyte-endothelial adhesion molecules. Blood 84:2068-2101 (Pubitemid 24296363)
-
(1994)
Blood
, vol.84
, Issue.7
, pp. 2068-2101
-
-
Carlos, T.M.1
Harlan, J.M.2
-
9
-
-
16644389516
-
HIFs, hypoxia, and vascular development
-
DOI 10.1016/S0070-2153(04)62002-3, PII S0070215304620023, Developmental Vascular Biology
-
Covello KL, Simon MC (2004) HIFs, hypoxia, and vascular development. Curr Top Dev Biol 62:37-54 (Pubitemid 39752374)
-
(2004)
Current Topics in Developmental Biology
, vol.62
, pp. 37-54
-
-
Covello, K.L.1
Simon, M.C.2
-
10
-
-
0037423948
-
HIF-1α is essential for myeloid cell-mediated inflammation
-
DOI 10.1016/S0092-8674(03)00154-5
-
Cramer T, Yamanishi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V et al (2003) HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell 112:645-657 (Pubitemid 36331777)
-
(2003)
Cell
, vol.112
, Issue.5
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Forster, I.4
Pawlinski, R.5
Mackman, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
Firestein, G.S.11
Gerber, H.-P.12
Ferrara, N.13
Johnson, R.S.14
-
11
-
-
0026006260
-
The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome
-
Dinarello CA (1991) The proinflammatory cytokines interleukin-1 and tumor necrosis factor and treatment of the septic shock syndrome. J Infect Dis 163:1177-1184
-
(1991)
J Infect Dis
, vol.163
, pp. 1177-1184
-
-
Dinarello, C.A.1
-
12
-
-
0026661026
-
Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha
-
Doherty GM, Lange JR, Langstein HN, Alexander HR, Buresh CM, Norton JA (1992) Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha. J Immunol 149:1666-1670
-
(1992)
J Immunol
, vol.149
, pp. 1666-1670
-
-
Doherty, G.M.1
Lange, J.R.2
Langstein, H.N.3
Alexander, H.R.4
Buresh, C.M.5
Norton, J.A.6
-
13
-
-
68249140395
-
Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia
-
Fang HY, Hughes R, Murdoch C, Coffelt SB, Biswas SK, Harris AL, Johnson RS, Imityaz HZ, Simon MC, Fredlund E et al (2009) Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia. Blood 114:844-859
-
(2009)
Blood
, vol.114
, pp. 844-859
-
-
Fang, H.Y.1
Hughes, R.2
Murdoch, C.3
Coffelt, S.B.4
Biswas, S.K.5
Harris, A.L.6
Johnson, R.S.7
Imityaz, H.Z.8
Simon, M.C.9
Fredlund, E.10
-
14
-
-
33745003285
-
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB
-
DOI 10.1042/BJ20051839
-
Frede S, Stockmann C, Freitag P, Fandrey J (2006) Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB. Biochem J 396:517-527 (Pubitemid 44228166)
-
(2006)
Biochemical Journal
, vol.396
, Issue.3
, pp. 517-527
-
-
Frede, S.1
Stockmann, C.2
Freitag, P.3
Fandrey, J.4
-
15
-
-
0034658009
-
Clinical implications of expression of interleukin 8 related to angiogenesis in uterine cervical cancers
-
Fujimoto J, Sakaguchi H, Aoki I, Tamaya T (2000) Clinical implications of expression of interleukin 8 related to angiogenesis in uterine cervical cancers. Cancer Res 60:2632-2635 (Pubitemid 30318237)
-
(2000)
Cancer Research
, vol.60
, Issue.10
, pp. 2632-2635
-
-
Fujimoto, J.1
Sakaguchi, H.2
Aoki, I.3
Tamaya, T.4
-
16
-
-
0037265240
-
Alternative activation of macrophages
-
DOI 10.1038/nri978
-
Gordon S (2003) Alternative activation of macrophages. Nat Rev Immunol 3:23-35 (Pubitemid 37328697)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.1
, pp. 23-35
-
-
Gordon, S.1
-
17
-
-
0033998433
-
The macrophage - A novel system to deliver gene therapy to pathological hypoxia
-
Griffiths L, Binley K, Iqball S, Kan O, Maxwell P, Ratcliffe P, Lewis C, Harris A, Kingsman S, Naylor S (2000) The macrophage -a novel system to deliver gene therapy to pathological hypoxia. Gene Ther 7:255-262 (Pubitemid 30113775)
-
(2000)
Gene Therapy
, vol.7
, Issue.3
, pp. 255-262
-
-
Griffiths, L.1
Binley, K.2
Iqball, S.3
Kan, O.4
Maxwell, P.5
Ratcliffe, P.6
Lewis, C.7
Harris, A.8
Kingsman, S.9
Naylor, S.10
-
18
-
-
0035101398
-
Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation - A potential mechanism
-
DOI 10.1002/1521-4141(200102)31:2<480::AID-IMMU480>3.0.CO;2-L
-
Grimshaw MJ, Balkwill FR (2001) Inhibition of monocyte and macrophage chemotaxis by hypoxia and inflammation -a potential mechanism. Eur J Immunol 31:480-489 (Pubitemid 32166603)
-
(2001)
European Journal of Immunology
, vol.31
, Issue.2
, pp. 480-489
-
-
Grimshaw, M.J.1
Balkwill, F.R.2
-
19
-
-
0029086009
-
Hypoxia prolongs neutrophil survival in vitro
-
Hannah S, Mecklenburgh K, Rahman I, Bellingan GJ, Greening A, Haslett C, Chilvers ER (1995) Hypoxia prolongs neutrophil survival in vitro. FEBS Lett 372:233-237
-
(1995)
FEBS Lett
, vol.372
, pp. 233-237
-
-
Hannah, S.1
Mecklenburgh, K.2
Rahman, I.3
Bellingan, G.J.4
Greening, A.5
Haslett, C.6
Chilvers, E.R.7
-
20
-
-
0025134961
-
The role of IFN-γ in the pathology of experimental endotoxemia
-
Heinzel FP (1990) The role of IFN-gamma in the pathology of experimental endotoxemia. J Immunol 145:2920-2924 (Pubitemid 20382561)
-
(1990)
Journal of Immunology
, vol.145
, Issue.9
, pp. 2920-2924
-
-
Heinzel, F.P.1
-
21
-
-
0035925098
-
Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
-
Hockel M, Vaupel P (2001) Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst 93:266-276 (Pubitemid 32219813)
-
(2001)
Journal of the National Cancer Institute
, vol.93
, Issue.4
, pp. 266-276
-
-
Hockel, M.1
Vaupel, P.2
-
22
-
-
0027408695
-
Interleukin 10 protects mice from lethal endotoxemia
-
Howard M, Muchamuel T, Andrade S, Menon S (1993) Interleukin 10 protects mice from lethal endotoxemia. J Exp Med 177:1205-1208 (Pubitemid 23097411)
-
(1993)
Journal of Experimental Medicine
, vol.177
, Issue.4
, pp. 1205-1208
-
-
Howard, M.1
Muchamuel, T.2
Andrade, S.3
Menon, S.4
-
23
-
-
0345491599
-
Differential Roles of Hypoxia-Inducible Factor 1α (HIF-1α) and HIF-2α in Hypoxic Gene Regulation
-
DOI 10.1128/MCB.23.24.9361-9374.2003
-
Hu CJ, Wang LY, Chodosh LA, Keith B, Simon MC (2003) Differential roles of hypoxiainducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation. Mol Cell Biol 23:9361-9374 (Pubitemid 37499822)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.24
, pp. 9361-9374
-
-
Hu, C.-J.1
Wang, L.-Y.2
Chodosh, L.A.3
Keith, B.4
Simon, M.C.5
-
24
-
-
0035917313
-
2 sensing
-
Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin WG Jr. (2001) HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292:464-468 (Pubitemid 32335941)
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
25
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ et al (2001) Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292:468-472 (Pubitemid 32335942)
-
(2001)
Science
, vol.292
, Issue.5516
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.-M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Von Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
26
-
-
44449117540
-
Hypoxia and hypoxia-inducible factor-1 alpha modulate lipopolysaccharide-induced dendritic cell activation and function
-
Jantsch J, Chakravortty D, Turza N, Prechtel AT, Buchholz B, Gerlach RG, Volke M, Glasner J, Warnecke C, Wiesener MS et al (2008) Hypoxia and hypoxia-inducible factor-1 alpha modulate lipopolysaccharide-induced dendritic cell activation and function. J Immunol 180:4697-4705
-
(2008)
J Immunol
, vol.180
, pp. 4697-4705
-
-
Jantsch, J.1
Chakravortty, D.2
Turza, N.3
Prechtel, A.T.4
Buchholz, B.5
Gerlach, R.G.6
Volke, M.7
Glasner, J.8
Warnecke, C.9
Wiesener, M.S.10
-
27
-
-
34047258169
-
Cellular mechanisms in sepsis
-
Jean-Baptiste E (2007) Cellular mechanisms in sepsis. J Intensive Care Med 22:63-72
-
(2007)
J Intensive Care Med
, vol.22
, pp. 63-72
-
-
Jean-Baptiste, E.1
-
28
-
-
0038434290
-
Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxaminestimulated HMC-1 cells
-
Jeong HJ, Chung HS, Lee BR, Kim SJ, Yoo SJ, Hong SH, Kim HM (2003) Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxaminestimulated HMC-1 cells. Biochem Biophys Res Commun 306:805-811
-
(2003)
Biochem Biophys Res Commun
, vol.306
, pp. 805-811
-
-
Jeong, H.J.1
Chung, H.S.2
Lee, B.R.3
Kim, S.J.4
Yoo, S.J.5
Hong, S.H.6
Kim, H.M.7
-
29
-
-
0037444823
-
Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor κB activation
-
DOI 10.1042/BJ20021279
-
Jung Y, Isaacs JS, Lee S, Trepel J, Liu ZG, Neckers L (2003a) Hypoxia-inducible factor induction by tumour necrosis factor in normoxic cells requires receptor-interacting protein-dependent nuclear factor kappa B activation. Biochem J 370:1011-1017 (Pubitemid 36399095)
-
(2003)
Biochemical Journal
, vol.370
, Issue.3
, pp. 1011-1017
-
-
Jung, Y.1
Isaacs, J.S.2
Lee, S.3
Trepel, J.4
Liu, Z.-G.5
Neckers, L.6
-
30
-
-
0347334750
-
IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
-
Jung YJ, Isaacs JS, Lee S, Trepel J, Neckers L (2003b) IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. Faseb J 17:2115-2117
-
(2003)
Faseb J
, vol.17
, pp. 2115-2117
-
-
Jung, Y.J.1
Isaacs, J.S.2
Lee, S.3
Trepel, J.4
Neckers, L.5
-
31
-
-
43149084780
-
Prognostic significance of HIF-2α expression on tumor infiltrating macrophages in patients with uterine cervical cancer undergoing radiotherapy
-
DOI 10.2152/jmi.55.78
-
Kawanaka T, Kubo A, Ikushima H, Sano T, Takegawa Y, Nishitani H (2008) Prognostic significance of HIF-2alpha expression on tumor infiltrating macrophages in patients with uterine cervical cancer undergoing radiotherapy. J Med Invest 55:78-86 (Pubitemid 351643597)
-
(2008)
Journal of Medical Investigation
, vol.55
, Issue.1-2
, pp. 78-86
-
-
Kawanaka, T.1
Kubo, A.2
Ikushima, H.3
Sano, T.4
Takegawa, Y.5
Nishitani, H.6
-
32
-
-
0023836831
-
Macrophages in human breast disease: A quantitative immunohistochemical study
-
Kelly PM, Davison RS, Bliss E, McGee JO (1988) Macrophages in human breast disease: a quantitative immunohistochemical study. Br J Cancer 57:174-177 (Pubitemid 18085399)
-
(1988)
British Journal of Cancer
, vol.57
, Issue.2
, pp. 174-177
-
-
Kelly, P.M.A.1
Davison, R.S.2
Bliss, E.3
McGee, J.O.4
-
33
-
-
77949383238
-
Hypoxic stress up-regulates the expression of toll-like receptor 4 in macrophages via hypoxia-inducible factor
-
Kim SY, Choi YJ, Joung SM, Lee BH, Jung YS, Lee JY (2009) Hypoxic stress up-regulates the expression of toll-like receptor 4 in macrophages via hypoxia-inducible factor. Immunology 4:516-524
-
(2009)
Immunology
, vol.4
, pp. 516-524
-
-
Kim, S.Y.1
Choi, Y.J.2
Joung, S.M.3
Lee, B.H.4
Jung, Y.S.5
Lee, J.Y.6
-
34
-
-
3142752573
-
2 integrin gene expression
-
DOI 10.1073/pnas.0401339101
-
Kong T, Eltzschig HK, Karhausen J, Colgan SP, Shelley CS (2004) Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression. Proc Natl Acad Sci USA 101:10440-10445 (Pubitemid 38924944)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.28
, pp. 10440-10445
-
-
Kong, T.1
Eltzschig, H.K.2
Karhausen, J.3
Colgan, S.P.4
Shelley, C.S.5
-
35
-
-
0029975877
-
Tumor necrosis factor α and interleukin 1β are responsible for in vitro myocardial cell depression induced by human septic shock serum
-
DOI 10.1084/jem.183.3.949
-
Kumar A, Thota V, Dee L, Olson J, Uretz E, Parrillo JE (1996) Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum. J Exp Med 183:949-958 (Pubitemid 26113964)
-
(1996)
Journal of Experimental Medicine
, vol.183
, Issue.3
, pp. 949-958
-
-
Kumar, A.1
Thota, V.2
Dee, L.3
Olson, J.4
Uretz, E.5
Parrillo, J.E.6
-
36
-
-
0036469038
-
Asparagine hydroxylation of the HIF transactivation domain: A hypoxic switch
-
DOI 10.1126/science.1068592
-
Lando D, Peet DJ, Whelan DA, Gorman JJ, Whitelaw ML (2002) Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch. Science 295:858-861 (Pubitemid 34118367)
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 858-861
-
-
Lando, D.1
Peet, D.J.2
Whelan, D.A.3
Gorman, J.J.4
Whitelaw, M.L.5
-
37
-
-
54049109247
-
Mast cells can mediate vascular permeability through regulation of the PI3KHIF-1alpha-VEGF axis
-
Lee KS, Kim SR, Park SJ, Min KH, Lee KY, Choe YH, Park SY, Chai OH, Zhang X, Song CH, Lee YC (2008) Mast cells can mediate vascular permeability through regulation of the PI3KHIF-1alpha-VEGF axis. Am J Respir Crit Care Med 178:787-797
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 787-797
-
-
Lee, K.S.1
Kim, S.R.2
Park, S.J.3
Min, K.H.4
Lee, K.Y.5
Choe, Y.H.6
Park, S.Y.7
Chai, O.H.8
Zhang, X.9
Song, C.H.10
Lee, Y.C.11
-
39
-
-
0028080215
-
Cytokine networks in solid human tumors: Regulation of angiogenesis
-
Leek RD, Harris AL, Lewis CE (1994) Cytokine networks in solid human tumors: regulation of angiogenesis. J Leukoc Biol 56:423-435 (Pubitemid 24319901)
-
(1994)
Journal of Leukocyte Biology
, vol.56
, Issue.4
, pp. 423-435
-
-
Leek, R.D.1
Harris, A.L.2
Lewis, C.E.3
-
40
-
-
0029816609
-
Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
-
Leek RD, Lewis CE, Whitehouse R, Greenall M, Clarke J, Harris AL (1996) Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 56:4625-4629 (Pubitemid 26338061)
-
(1996)
Cancer Research
, vol.56
, Issue.20
, pp. 4625-4629
-
-
Leek, R.D.1
Lewis, C.E.2
Whitehouse, R.3
Greenall, M.4
Clarke, J.5
Harris, A.L.6
-
41
-
-
0036493984
-
Relation of hypoxia-inducible factor-2α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
-
Leek RD, Talks KL, Pezzella F, Turley H, Campo L, Brown NS, Bicknell R, Taylor M, Gatter KC, Harris AL (2002) Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Res 62:1326-1329 (Pubitemid 34407787)
-
(2002)
Cancer Research
, vol.62
, Issue.5
, pp. 1326-1329
-
-
Leek, R.D.1
Talks, K.L.2
Pezzella, F.3
Turley, H.4
Campo, L.5
Brown, N.S.6
Bicknell, R.7
Taylor, M.8
Gatter, K.C.9
Harris, A.L.10
-
42
-
-
31544441610
-
Distinct role of macrophages in different tumor microenvironments
-
DOI 10.1158/0008-5472.CAN-05-4005
-
Lewis CE, Pollard JW (2006) Distinct role of macrophages in different tumor microenvironments. Cancer Res 66:605-612 (Pubitemid 43165918)
-
(2006)
Cancer Research
, vol.66
, Issue.2
, pp. 605-612
-
-
Lewis, C.E.1
Pollard, J.W.2
-
43
-
-
0033405817
-
Macrophage responses to hypoxia: Relevance to disease mechanisms
-
Lewis JS, Lee JA, Underwood JC, Harris AL, Lewis CE (1999) Macrophage responses to hypoxia: relevance to disease mechanisms. J Leukoc Biol 66:889-900 (Pubitemid 30010512)
-
(1999)
Journal of Leukocyte Biology
, vol.66
, Issue.6
, pp. 889-900
-
-
Lewis, J.S.1
Lee, J.A.2
Underwood, J.C.E.3
Harris, A.L.4
Lewis, C.E.5
-
44
-
-
0035911221
-
Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy
-
Lin EY, Nguyen AV, Russell RG, Pollard JW (2001) Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193:727-740
-
(2001)
J Exp Med
, vol.193
, pp. 727-740
-
-
Lin, E.Y.1
Nguyen, A.V.2
Russell, R.G.3
Pollard, J.W.4
-
45
-
-
0034266661
-
Tumor associated macrophages in human prostate cancer: Relation to clinicopathological variables and survival
-
Lissbrant IF, Stattin P, Wikstrom P, Damber JE, Egevad L, Bergh A (2000) Tumor associated macrophages in human prostate cancer: relation to clinicopathological variables and survival. Int J Oncol 17:445-451
-
(2000)
Int J Oncol
, vol.17
, pp. 445-451
-
-
Lissbrant, I.F.1
Stattin, P.2
Wikstrom, P.3
Damber, J.E.4
Egevad, L.5
Bergh, A.6
-
46
-
-
0031019222
-
Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production
-
Liu Y, Hulten LM, Wiklund O (1997) Macrophages isolated from human atherosclerotic plaques produce IL-8, and oxysterols may have a regulatory function for IL-8 production. Arterioscler Thromb Vasc Biol 17:317-323 (Pubitemid 27098190)
-
(1997)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.17
, Issue.2
, pp. 317-323
-
-
Liu, Y.1
Hulten, L.M.2
Wiklund, O.3
-
47
-
-
33846839443
-
Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma
-
DOI 10.1016/j.ccr.2006.12.016, PII S1535610807000207
-
Luedde T, Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, Roskams T, Trautwein C, Pasparakis M (2007) Deletion of NEMO/IKKgamma in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 11:119-132 (Pubitemid 46209851)
-
(2007)
Cancer Cell
, vol.11
, Issue.2
, pp. 119-132
-
-
Luedde, T.1
Beraza, N.2
Kotsikoris, V.3
Van Loo, G.4
Nenci, A.5
De Vos, R.6
Roskams, T.7
Trautwein, C.8
Pasparakis, M.9
-
48
-
-
21244472975
-
IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis
-
DOI 10.1016/j.cell.2005.04.014, PII S0092867405003946
-
Maeda S, Kamata H, Luo JL, Leffert H, Karin M (2005) IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 121:977-990 (Pubitemid 40884391)
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 977-990
-
-
Maeda, S.1
Kamata, H.2
Luo, J.-L.3
Leffert, H.4
Karin, M.5
-
49
-
-
0035887011
-
FIH-1: A novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
-
DOI 10.1101/gad.924501
-
Mahon PC, Hirota K, Semenza GL (2001) FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 15:2675-2686 (Pubitemid 32988878)
-
(2001)
Genes and Development
, vol.15
, Issue.20
, pp. 2675-2686
-
-
Mahon, P.C.1
Hirota, K.2
Semenza, G.L.3
-
51
-
-
0035903468
-
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
-
DOI 10.1093/emboj/20.18.5197
-
Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ (2001) Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J 20:5197-5206 (Pubitemid 32910914)
-
(2001)
EMBO Journal
, vol.20
, Issue.18
, pp. 5197-5206
-
-
Masson, N.1
Willam, C.2
Maxwell, P.H.3
Pugh, C.W.4
Ratcliffe, P.J.5
-
52
-
-
33747691662
-
Transforming growth factor β1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression
-
DOI 10.1074/jbc.M604507200
-
McMahon S, Charbonneau M, Grandmont S, Richard DE, Dubois CM (2006) Transforming growth factor beta1 induces hypoxia-inducible factor-1 stabilization through selective inhibition of PHD2 expression. J Biol Chem 281:24171-24181 (Pubitemid 44274191)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.34
, pp. 24171-24181
-
-
McMahon, S.1
Charbonneau, M.2
Grandmont, S.3
Richard, D.E.4
Dubois, C.M.5
-
53
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser DM, Edwards JP (2008) Exploring the full spectrum of macrophage activation. Nat Rev Immunol 8:958-969
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
54
-
-
4944244259
-
Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues
-
DOI 10.1182/blood-2004-03-1109
-
Murdoch C, Giannoudis A, Lewis CE (2004) Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues. Blood 104:2224-2234 (Pubitemid 39331817)
-
(2004)
Blood
, vol.104
, Issue.8
, pp. 2224-2234
-
-
Murdoch, C.1
Giannoudis, A.2
Lewis, C.E.3
-
55
-
-
27744603002
-
Hypoxia regulates macrophage functions in inflammation
-
Murdoch C, Muthana M, Lewis CE (2005) Hypoxia regulates macrophage functions in inflammation. J Immunol 175:6257-6263 (Pubitemid 41598863)
-
(2005)
Journal of Immunology
, vol.175
, Issue.10
, pp. 6257-6263
-
-
Murdoch, C.1
Muthana, M.2
Lewis, C.E.3
-
56
-
-
67651212055
-
Hypoxia The role of hypoxia and HIFdependent signalling events in rheumatoid arthritis
-
Muz B, Khan MN, Kiriakidis S, Paleolog EM (2009) Hypoxia. The role of hypoxia and HIFdependent signalling events in rheumatoid arthritis. Arthritis Res Ther 11:201
-
(2009)
Arthritis Res Ther
, vol.11
, pp. 201
-
-
Muz, B.1
Khan, M.N.2
Kiriakidis, S.3
Paleolog, E.M.4
-
57
-
-
0029847088
-
Expression of very low density lipoprotein receptor mRNA in rabbit atherosclerotic lesions
-
Nakazato K, Ishibashi T, Shindo J, Shiomi M, Maruyama Y (1996) Expression of very low density lipoprotein receptor mRNA in rabbit atherosclerotic lesions. Am J Pathol 149: 1831-1838 (Pubitemid 26415204)
-
(1996)
American Journal of Pathology
, vol.149
, Issue.6
, pp. 1831-1838
-
-
Nakazato, K.1
Ishibashi, T.2
Shindo, J.3
Shiomi, M.4
Maruyama, Y.5
-
58
-
-
0035097980
-
Expression of very low density lipoprotein receptor mRNA in circulating human monocytes: Its up-regulation by hypoxia
-
DOI 10.1016/S0021-9150(00)00580-3, PII S0021915000005803
-
Nakazato K, Ishibashi T, Nagata K, Seino Y, Wada Y, Sakamoto T, Matsuoka R, Teramoto T, Sekimata M, Homma Y, Maruyama Y (2001) Expression of very low density lipoprotein receptor mRNA in circulating human monocytes: its up-regulation by hypoxia. Atherosclerosis 155:439-444 (Pubitemid 32209315)
-
(2001)
Atherosclerosis
, vol.155
, Issue.2
, pp. 439-444
-
-
Nakazato, K.1
Ishibashi, T.2
Nagata, K.3
Seino, Y.4
Wada, Y.5
Sakamoto, T.6
Matsuoka, R.7
Teramoto, T.8
Sekimata, M.9
Homma, Y.10
Maruyama, Y.11
-
59
-
-
34447327216
-
Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production
-
DOI 10.1126/science.1140485
-
Naugler WE, Sakurai T, Kim S, Maeda S, Kim K, Elsharkawy AM, Karin M (2007) Gender disparity in liver cancer due to sex differences in MyD88-dependent IL-6 production. Science 317:121-124 (Pubitemid 47056470)
-
(2007)
Science
, vol.317
, Issue.5834
, pp. 121-124
-
-
Naugler, W.E.1
Sakurai, T.2
Kim, S.3
Maeda, S.4
Kim, K.5
Elsharkawy, A.M.6
Karin, M.7
-
60
-
-
0030820388
-
Endotoxin-induced lethality in neonatal mice is counteracted by interleukin-10 (IL-10) and exacerbated by anti-IL-10
-
Nicoletti F, Mancuso G, Ciliberti FA, Beninati C, Carbone M, Franco S, Cusumano V (1997) Endotoxin-induced lethality in neonatal mice is counteracted by interleukin-10 (IL-10) and exacerbated by anti-IL-10. Clin Diagn Lab Immunol 4:607-610 (Pubitemid 27448631)
-
(1997)
Clinical and Diagnostic Laboratory Immunology
, vol.4
, Issue.5
, pp. 607-610
-
-
Nicoletti, F.1
Mancuso, G.2
Ciliberti, F.A.3
Beninati, C.4
Carbone, M.5
Franco, S.6
Cusumano, V.7
-
61
-
-
39749196227
-
LPS induces hypoxia-inducible factor 1 activation in macrophage- differentiated cells in a reactive oxygen species-dependent manner
-
DOI 10.1089/ars.2007.1825
-
Nishi K, Oda T, Takabuchi S, Oda S, Fukuda K, Adachi T, Semenza GL, Shingu K, Hirota K (2008) LPS induces hypoxia-inducible factor 1 activation in macrophage-differentiated cells in a reactive oxygen species-dependent manner. Antioxid Redox Signal 10:983-995 (Pubitemid 351301367)
-
(2008)
Antioxidants and Redox Signaling
, vol.10
, Issue.5
, pp. 983-995
-
-
Nishi, K.1
Oda, T.2
Takabuchi, S.3
Oda, S.4
Fukuda, K.5
Adachi, T.6
Semenza, G.L.7
Shingu, K.8
Hirota, K.9
-
62
-
-
33745686086
-
Activation of hypoxia-inducible factor 1 during macrophage differentiation
-
Oda T, Hirota K, Nishi K, Takabuchi S, Oda S, Yamada H, Arai T, Fukuda K, Kita T, Adachi T et al (2006) Activation of hypoxia-inducible factor 1 during macrophage differentiation. Am J Physiol Cell Physiol 291:C104-C113
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Oda, T.1
Hirota, K.2
Nishi, K.3
Takabuchi, S.4
Oda, S.5
Yamada, H.6
Arai, T.7
Fukuda, K.8
Kita, T.9
Adachi, T.10
-
63
-
-
0027920980
-
Pathogenetic mechanisms of septic shock
-
Parrillo JE (1993) Pathogenetic mechanisms of septic shock. N Engl J Med 328:1471-1477
-
(1993)
N Engl J Med
, vol.328
, pp. 1471-1477
-
-
Parrillo, J.E.1
-
64
-
-
0347719258
-
The Transcription Factors Hypoxia-Inducible Factor 1α and Ets-1 Colocalize in the Hypoxic Synovium of Inflamed Joints in Adjuvant-Induced Arthritis
-
DOI 10.1002/art.11473
-
Peters CL, Morris CJ, Mapp PI, Blake DR, Lewis CE, Winrow VR (2004) The transcription factors hypoxia-inducible factor 1alpha and Ets-1 colocalize in the hypoxic synovium of inflamed joints in adjuvant-induced arthritis. Arthritis Rheum 50:291-296 (Pubitemid 38084314)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.1
, pp. 291-296
-
-
Peters, C.L.1
Morris, C.J.2
Mapp, P.I.3
Blake, D.R.4
Lewis, C.E.5
Winrow, V.R.6
-
65
-
-
22144492953
-
HIF-1α expression regulates the bactericidal capacity of phagocytes
-
DOI 10.1172/JCI23865
-
Peyssonnaux C, Datta V, Cramer T, Doedens A, Theodorakis EA, Gallo RL, Hurtado-Ziola N, Nizet V, Johnson RS (2005) HIF-1alpha expression regulates the bactericidal capacity of phagocytes. J Clin Invest 115:1806-1815 (Pubitemid 40979719)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.7
, pp. 1806-1815
-
-
Peyssonnaux, C.1
Datta, V.2
Cramer, T.3
Doedens, A.4
Theodorakis, E.A.5
Gallo, R.L.6
Hurtado-Ziola, N.7
Nizet, V.8
Johnson, R.S.9
-
66
-
-
34250158361
-
Cutting edge: Essential role of hypoxia inducible factor-1α in development of lipopolysaccharide-induced sepsis
-
Peyssonnaux C, Cejudo-Martin P, Doedens A, Zinkernagel AS, Johnson RS, Nizet V (2007) Cutting edge: Essential role of hypoxia inducible factor-1alpha in development of lipopolysaccharide-induced sepsis. J Immunol 178:7516-7519 (Pubitemid 46898018)
-
(2007)
Journal of Immunology
, vol.178
, Issue.12
, pp. 7516-7519
-
-
Peyssonnaux, C.1
Cejudo-Martin, P.2
Doedens, A.3
Zinkernagel, A.S.4
Johnson, R.S.5
Nizet, V.6
-
67
-
-
0347123433
-
Tumour-educated macrophages promote tumour progression and metastasis
-
Pollard JW (2004) Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 4:71-78 (Pubitemid 38082155)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.1
, pp. 71-78
-
-
Pollard, J.W.1
-
68
-
-
70350635653
-
Host cholesterol and inflammation as common key regulators of toxoplasmosis and artherosclerosis development
-
Portugal LR, Fernandes LR, Alvarez-Leite JI (2009) Host cholesterol and inflammation as common key regulators of toxoplasmosis and artherosclerosis development. Expert Rev Anti Infect Ther 7:807-819
-
(2009)
Expert Rev Anti Infect Ther
, vol.7
, pp. 807-819
-
-
Portugal, L.R.1
Fernandes, L.R.2
Alvarez-Leite, J.I.3
-
69
-
-
44849100198
-
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
-
DOI 10.1038/nature06905, PII NATURE06905
-
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M (2008) NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha. Nature 453:807-811 (Pubitemid 351793778)
-
(2008)
Nature
, vol.453
, Issue.7196
, pp. 807-811
-
-
Rius, J.1
Guma, M.2
Schachtrup, C.3
Akassoglou, K.4
Zinkernagel, A.S.5
Nizet, V.6
Johnson, R.S.7
Haddad, G.G.8
Karin, M.9
-
70
-
-
0242493026
-
Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages
-
DOI 10.1016/S0021-9150(03)00302-2
-
Rydberg EK, Salomonsson L, Hulten LM, Noren K, Bondjers G, Wiklund O, Bjornheden T, Ohlsson BG (2003) Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages. Atherosclerosis 170:245-252 (Pubitemid 37377796)
-
(2003)
Atherosclerosis
, vol.170
, Issue.2
, pp. 245-252
-
-
Rydberg, E.K.1
Salomonsson, L.2
Hulten, L.M.3
Noren, K.4
Bondjers, G.5
Wiklund, O.6
Bjornheden, T.7
Ohlsson, B.G.8
-
71
-
-
0036232662
-
Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1α is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP
-
DOI 10.1128/MCB.22.9.2984-2992.2002
-
Sang N, Fang J, Srinivas V, Leshchinsky I, Caro J (2002) Carboxyl-terminal transactivation activity of hypoxia-inducible factor 1 alpha is governed by a von Hippel-Lindau protein-independent, hydroxylation-regulated association with p300/CBP. Mol Cell Biol 22:2984-2992 (Pubitemid 34437457)
-
(2002)
Molecular and Cellular Biology
, vol.22
, Issue.9
, pp. 2984-2992
-
-
Sang, N.1
Fang, J.2
Srinivas, V.3
Leshchinsky, I.4
Caro, J.5
-
72
-
-
85047682984
-
Regulation of oxygen homeostasis by hypoxia-inducible factor 1
-
Semenza GL (2009) Regulation of oxygen homeostasis by hypoxia-inducible factor 1. Physiology (Bethesda) 24:97-106
-
(2009)
Physiology (Bethesda)
, vol.24
, pp. 97-106
-
-
Semenza, G.L.1
-
73
-
-
33645991795
-
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anticancer therapy
-
Sica A, Schioppa T, Mantovani A, Allavena P (2006) Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anticancer therapy. Eur J Cancer 42:717-727
-
(2006)
Eur J Cancer
, vol.42
, pp. 717-727
-
-
Sica, A.1
Schioppa, T.2
Mantovani, A.3
Allavena, P.4
-
74
-
-
38849135497
-
Synovial Hypoxia as a Cause of Tendon Rupture in Rheumatoid Arthritis
-
DOI 10.1016/j.jhsa.2007.09.002, PII S0363502307007770
-
Sivakumar B, Akhavani MA, Winlove CP, Taylor PC, Paleolog EM, Kang N (2008) Synovial hypoxia as a cause of tendon rupture in rheumatoid arthritis. J Hand Surg Am 33:49-58 (Pubitemid 351193088)
-
(2008)
Journal of Hand Surgery
, vol.33
, Issue.1
, pp. 49-58
-
-
Sivakumar, B.1
Akhavani, M.A.2
Winlove, C.P.3
Taylor, P.C.4
Paleolog, E.M.5
Kang, N.6
-
75
-
-
0029164732
-
Neutralization of IL-10 increases lethality in endotoxemia. Cooperative effects of macrophage inflammatory protein-2 and tumor necrosis factor
-
Standiford TJ, Strieter RM, Lukacs NW, Kunkel SL (1995) Neutralization of IL-10 increases lethality in endotoxemia. Cooperative effects of macrophage inflammatory protein-2 and tumor necrosis factor. J Immunol 155:2222-2229
-
(1995)
J Immunol
, vol.155
, pp. 2222-2229
-
-
Standiford, T.J.1
Strieter, R.M.2
Lukacs, N.W.3
Kunkel, S.L.4
-
76
-
-
0031992840
-
Angiogenesis in rheumatoid arthritis: Pathogenic and clinical significance
-
Szekanecz Z, Szegedi G, Koch AE (1998) Angiogenesis in rheumatoid arthritis: pathogenic and clinical significance. J Investig Med 46:27-41 (Pubitemid 128452767)
-
(1998)
Journal of Investigative Medicine
, vol.46
, Issue.2
, pp. 27-41
-
-
Szekanecz, Z.1
Szegedi, G.2
Koch, A.E.3
-
77
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
-
Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL (2000) The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 157:411-421 (Pubitemid 30626905)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.2
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
Harris, A.L.7
-
78
-
-
0023491364
-
Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia
-
DOI 10.1038/330662a0
-
Tracey KJ, Fong Y, Hesse DG, Manogue KR, Lee AT, Kuo GC, Lowry SF, Cerami A (1987) Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330:662-664 (Pubitemid 18005583)
-
(1987)
Nature
, vol.330
, Issue.6149
, pp. 662-664
-
-
Tracey, K.J.1
Fong, Y.2
Hesse, D.G.3
Manogue, K.R.4
Lee, A.T.5
Kuo, G.C.6
Lowry, S.F.7
Cerami, A.8
-
79
-
-
13244288781
-
The "cytokine profile" a code for sepsis
-
Ulloa L, Tracey KJ (2005) The "cytokine profile": a code for sepsis. Trends Mol Med 11:56-63
-
(2005)
Trends Mol Med
, vol.11
, pp. 56-63
-
-
Ulloa, L.1
Tracey, K.J.2
-
80
-
-
0034743861
-
Oxygenation status of malignant tumors: Pathogenesis of hypoxia and significance for tumor therapy
-
Vaupel P, Kelleher DK, Hockel M (2001) Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy. Semin Oncol 28:29-35 (Pubitemid 32522235)
-
(2001)
Seminars in Oncology
, vol.28
, Issue.2 SUPPL. 8
, pp. 29-35
-
-
Vaupel, P.1
Kelleher, D.K.2
Hockel, M.3
-
81
-
-
22444445691
-
The role of HIF-1α in myeloid cell inflammation
-
DOI 10.1016/j.it.2005.06.007, PII S1471490605001596
-
Walmsley SR, Cadwallader KA, Chilvers ER (2005a) The role of HIF-1alpha in myeloid cell inflammation. Trends Immunol 26:434-439 (Pubitemid 41008080)
-
(2005)
Trends in Immunology
, vol.26
, Issue.8
, pp. 434-439
-
-
Walmsley, S.R.1
Cadwallader, K.A.2
Chilvers, E.R.3
-
82
-
-
19944432390
-
Hypoxia-induced neutrophil survival is mediated by HIF-1α-dependent NF-κB activity
-
DOI 10.1084/jem.20040624
-
Walmsley SR, Print C, Farahi N, Peyssonnaux C, Johnson RS, Cramer T, Sobolewski A, Condliffe AM, Cowburn AS, Johnson N, Chilvers ER (2005b) Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity. J Exp Med 201:105-115 (Pubitemid 40130088)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.1
, pp. 105-115
-
-
Walmsley, S.R.1
Print, C.2
Farahi, N.3
Peyssonnaux, C.4
Johnson, R.S.5
Cramer, T.6
Sobolewski, A.7
Condliffe, A.M.8
Cowburn, A.S.9
Johnson, N.10
Chilvers, E.R.11
-
83
-
-
0345118952
-
Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis
-
DOI 10.1016/S0888-7543(03)00215-5
-
White JR, Harris RA, Lee SR, Craigon MH, Binley K, Price T, Beard GL, Mundy CR, Naylor S (2004) Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis. Genomics 83:1-8 (Pubitemid 37518254)
-
(2004)
Genomics
, vol.83
, Issue.1
, pp. 1-8
-
-
White, J.R.1
Harris, R.A.2
Lee, S.R.3
Craigon, M.H.4
Binley, K.5
Price, T.6
Beard, G.L.7
Mundy, C.R.8
Naylor, S.9
-
84
-
-
0035872479
-
Dynamic, site-specific interaction of hypoxia-inducible factor-1α with the von Hippel-Lindau tumor suppressor protein
-
Yu F, White SB, Zhao Q, Lee FS (2001) Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. Cancer Res 61:4136-4142 (Pubitemid 32720982)
-
(2001)
Cancer Research
, vol.61
, Issue.10
, pp. 4136-4142
-
-
Yu, F.1
White, S.B.2
Zhao, Q.3
Lee, F.S.4
-
85
-
-
0024518598
-
Adaptation to arterial wall hypoxia demonstrated in vivo with oxygen microcathodes
-
DOI 10.1016/0021-9150(89)90101-9
-
Zemplenyi T, Crawford DW, Cole MA (1989) Adaptation to arterial wall hypoxia demonstrated in vivo with oxygen microcathodes. Atherosclerosis 76:173-179 (Pubitemid 19101037)
-
(1989)
Atherosclerosis
, vol.76
, Issue.2-3
, pp. 173-179
-
-
Zemplenyi, T.1
Crawford, D.W.2
Cole, M.A.3
-
86
-
-
0038308573
-
Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-κB- dependent pathway
-
DOI 10.1091/mbc.E02-09-0598
-
Zhou J, Schmid T, Brune B (2003) Tumor necrosis factor-alpha causes accumulation of a ubiquitinated form of hypoxia inducible factor-1alpha through a nuclear factor-kappaBdependent pathway. Mol Biol Cell 14:2216-2225 (Pubitemid 36724315)
-
(2003)
Molecular Biology of the Cell
, vol.14
, Issue.6
, pp. 2216-2225
-
-
Zhou, J.1
Schmid, T.2
Brune, B.3
-
87
-
-
0031264674
-
Anti-interleukin-12 therapy protects mice in lethal endotoxemia but impairs bacterial clearance in murine Escherichia coli peritoneal sepsis
-
Zisman DA, Kunkel SL, Strieter RM, Gauldie J, Tsai WC, Bramson J, Wilkowski JM, Bucknell KA, Standiford TJ (1997) Anti-interleukin-12 therapy protects mice in lethal endotoxemia but impairs bacterial clearance in murine Escherichia coli peritoneal sepsis. Shock 8:349-356 (Pubitemid 127654348)
-
(1997)
Shock
, vol.8
, Issue.5
, pp. 349-356
-
-
Zisman, D.A.1
Kunkel, S.L.2
Strieter, R.M.3
Gauldie, J.4
Tsai, W.C.5
Bramson, J.6
Wilkowski, J.M.7
Bucknell, K.A.8
Standiford, T.J.9
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